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MRTO4 ,MRTO4 ,Q9UKD2
  • Uniprot Accession= Q9UKD2
  • Ensembl Transcript= ENST00000330263.4
  • Uniprot Name= MRTO4
  • Name= mRNA turnover protein 4 homolog
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 37
  • Number of Interaction partner in biogrid: 48
  • Number of Interaction partner in hippie: 133
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact 108 912 75 75 0
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 Not Cancer Driver No 2 hippie, biogrid 102 348 34 34 1
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
BET1 BET1 O15155 BET1 homolog chr7 Not Cancer Driver No 1 hippie 14 7 2 2 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 2 intact, hippie 50 150 30 30 0
BRIX1 BRIX1 Q8TDN6 Ribosome biogenesis protein BRX1 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 34 149 10 10 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CCDC86 CCDC86 Q9H6F5 Coiled-coil domain-containing protein 86 chr11 Not Cancer Driver No 1 hippie 36 360 36 36 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 40 1 0 0 0
CDKL2_ENST00000429927 CDKL2 Q92772 Cyclin-dependent kinase-like 2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 63 171 21 21 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 1 hippie 12 342 12 12 1
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 Not Cancer Driver No 1 hippie 50 173 7 7 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CTSS CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact, hippie 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX24 DDX24 Q9GZR7 ATP-dependent RNA helicase DDX24 chr14 Not Cancer Driver No 1 hippie, biogrid 86 452 40 40 0
DDX56 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 Not Cancer Driver No 1 hippie, biogrid 50 107 13 13 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 2 hippie, biogrid 33 198 17 17 3
DNAJC9 DNAJC9 Q8WXX5 DnaJ homolog subfamily C member 9 chr10 Not Cancer Driver No 1 hippie, biogrid 28 126 15 15 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
EBNA1BP2_ENST00000236051 EBNA1BP2 Q99848 Probable rRNA-processing protein EBP2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 254 34 34 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie, biogrid 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 1 hippie, biogrid 59 188 22 22 0
EIF2S2 EIF2S2 P20042 Eukaryotic translation initiation factor 2 subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 37 185 12 12 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact 147 211 38 38 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FBL FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 Not Cancer Driver No 2 hippie, biogrid 46 145 22 22 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 intact 238 228 44 44 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact 173 241 26 26 37
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 2 hippie, biogrid 103 533 66 66 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 Not Cancer Driver No 1 hippie, biogrid 93 283 35 35 0
GNL2 GNL2 Q13823 Nucleolar GTP-binding protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 87 446 51 51 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 Not Cancer Driver No 1 hippie 77 103 18 18 0
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 49 147 20 20 0
GTPBP4 GTPBP4 Q9BZE4 GTP-binding protein 4 chr10 Not Cancer Driver No 4 intact, hippie, biogrid 79 232 34 34 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 Not Cancer Driver No 1 intact 59 171 32 32 0
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 Not Cancer Driver No 1 hippie 32 413 32 32 0
HBP1_ENST00000468410 HBP1 O60381 HMG box-containing protein 1 chr7 Not Cancer Driver No 1 hippie 48 263 16 16 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 intact, hippie 35 203 29 29 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 intact, hippie 77 504 45 45 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie, biogrid 155 419 90 90 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KLF6 KLF6 Q99612 Krueppel-like factor 6 chr10 Census Yes 1 hippie 47 139 26 26 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 Not Cancer Driver No 1 intact, hippie 34 154 24 24 0
KRR1 KRR1 Q13601 KRR1 small subunit processome component homolog chr12 Not Cancer Driver No 1 hippie, biogrid 37 194 23 23 0
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 Not Cancer Driver No 1 intact, hippie 60 203 28 28 0
MAGEB10_ENST00000614159 MAGEB10 Q96LZ2 Melanoma-associated antigen B10 chrX Not Cancer Driver No 2 intact, hippie, biogrid 97 160 49 49 0
MAST1 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 204 1078 119 119 1
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 Not Cancer Driver No 1 intact, hippie, biogrid 180 172 76 76 0
MRPL1 MRPL1 Q9BYD6 39S ribosomal protein L1, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 44 46 5 5 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 Not Cancer Driver No 1 hippie 70 140 16 16 1
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 hippie 85 569 68 68 0
NIFK NIFK Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein chr2 Not Cancer Driver No 1 hippie, biogrid 32 148 15 15 0
NMD3_ENST00000351193 NMD3 Q96D46 60S ribosomal export protein NMD3 chr3 Not Cancer Driver No 1 hippie 67 104 20 20 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 77 281 31 31 0
NOL10 NOL10 Q9BSC4 Nucleolar protein 10 chr2 Not Cancer Driver No 1 hippie, biogrid 52 182 22 22 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 hippie, biogrid 116 510 72 72 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 intact, hippie 83 191 34 34 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NSA2 NSA2 O95478 Ribosome biogenesis protein NSA2 homolog chr5 Not Cancer Driver No 3 intact, hippie, biogrid 29 134 17 17 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 75 38 4 4 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PES1 PES1 O00541 Pescadillo homolog chr22 Not Cancer Driver No 1 hippie, biogrid 78 248 33 33 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 Not Cancer Driver No 1 hippie, biogrid 75 202 15 15 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 112 312 34 34 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
PTP4A1 PTP4A1 Q93096 Protein tyrosine phosphatase type IVA 1 chr6 Not Cancer Driver No 1 hippie 21 2 0 0 0
PUM3 PUM3 Q15397 Pumilio homolog 3 chr9 Not Cancer Driver No 1 hippie 74 170 19 19 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 174 291 99 99 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie 31 43 4 4 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 Not Cancer Driver No 1 hippie 25 15 4 4 3
RARA RARA P10276 Retinoic acid receptor alpha chr17 Census, Compendium Yes 1 hippie 70 167 14 14 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 52 19 2 2 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 Not Cancer Driver No 1 intact 144 280 43 43 1
RPL10A RPL10A P62906 60S ribosomal protein L10a chr6 Not Cancer Driver No 1 hippie, biogrid 22 16 0 0 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 intact, hippie 46 9 3 3 4
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 hippie 21 70 13 13 0
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 Not Cancer Driver No 1 hippie, biogrid 21 13 3 3 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie, biogrid 19 69 14 14 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 Census Yes 1 hippie, biogrid 57 96 17 17 2
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 intact, hippie 38 150 25 25 0
RRP15 RRP15 Q9Y3B9 RRP15-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 50 278 48 48 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
RSL24D1 RSL24D1 Q9UHA3 Probable ribosome biogenesis protein RLP24 chr15 Not Cancer Driver No 1 hippie 9 76 4 4 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 Not Cancer Driver No 1 intact 55 85 4 4 0
SDAD1 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 Not Cancer Driver No 1 hippie, biogrid 65 288 29 29 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SNU13_ENST00000355257 SNU13 P55769 NHP2-like protein 1 chr22 Not Cancer Driver No 1 hippie 17 2 0 0 0
SOX15_ENST00000538513 SOX15 O60248 Protein SOX-15 chr17 Not Cancer Driver No 1 intact, hippie 18 227 18 18 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie, biogrid 73 329 32 32 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 78 343 46 46 0
SRPK3 SRPK3 Q9UPE1 SRSF protein kinase 3 chrX Not Cancer Driver No 1 intact, hippie, biogrid 63 217 30 30 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 165 572 87 87 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 1 intact, hippie 122 516 93 93 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 Not Cancer Driver No 1 intact 219 126 22 22 10
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie 28 310 16 16 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 Not Cancer Driver No 1 intact, hippie 24 220 15 15 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 hippie, biogrid 24 184 14 14 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
WDR12 WDR12 Q9GZL7 Ribosome biogenesis protein WDR12 chr2 Not Cancer Driver No 1 hippie, biogrid 39 36 1 1 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie 112 64 7 7 0
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 75 216 30 30 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZFP41_ENST00000520584 ZFP41 Q8N8Y5 Zinc finger protein 41 homolog chr8 Not Cancer Driver No 3 intact, hippie, biogrid 33 100 17 17 0
ZNF622 ZNF622 Q969S3 Zinc finger protein 622 chr5 Not Cancer Driver No 1 hippie, biogrid 66 220 33 33 0
ZNF746_ENST00000340622 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 93 436 56 56 0