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MRPS21_ENST00000614145 ,MRPS21 ,P82921
  • Uniprot Accession= P82921
  • Ensembl Transcript= ENST00000614145.4
  • Uniprot Name= MRPS21
  • Name= 28S ribosomal protein S21, mitochondrial
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 25
  • Number of Interaction partner in biogrid: 80
  • Number of Interaction partner in hippie: 104
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABT1 ABT1 Q9ULW3 Activator of basal transcription 1 chr6 Not Cancer Driver No 1 hippie, biogrid 56 157 30 30 0
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 Not Cancer Driver No 1 hippie, biogrid 43 3 0 0 0
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 Not Cancer Driver No 1 intact, hippie 66 269 24 24 2
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 2 hippie, biogrid 18 104 8 8 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CCDC59 CCDC59 Q9P031 Thyroid transcription factor 1-associated protein 26 chr12 Not Cancer Driver No 1 hippie, biogrid 34 206 27 27 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 Not Cancer Driver No 1 hippie 61 138 15 15 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 48 0 0 0 2
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
DUSP11 DUSP11 O75319 RNA/RNP complex-1-interacting phosphatase chr2 Not Cancer Driver No 1 hippie 42 157 12 12 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 90 92 11 11 1
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FASTKD5 FASTKD5 Q7L8L6 FAST kinase domain-containing protein 5, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 86 94 8 8 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GATB GATB O75879 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial chr4 Not Cancer Driver No 1 biogrid 79 138 26 26 0
GFM1_ENST00000486715 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 74 79 7 7 4
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 Not Cancer Driver No 1 intact, hippie 84 134 27 27 0
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 49 147 20 20 0
GTF2H4 GTF2H4 Q92759 General transcription factor IIH subunit 4 chr6 Not Cancer Driver No 1 biogrid 46 30 5 5 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 intact, hippie 25 203 20 20 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 1 hippie, biogrid 67 304 25 25 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie, biogrid 77 504 45 45 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie, biogrid 36 25 6 6 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 Not Cancer Driver No 1 biogrid 68 73 19 19 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LDHD LDHD Q86WU2 Probable D-lactate dehydrogenase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 55 48 6 6 2
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 74 611 69 69 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 Census Yes 1 hippie 35 301 34 34 10
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 Not Cancer Driver No 1 biogrid 70 173 25 25 0
MAST1 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 204 1078 119 119 1
MCAT MCAT Q8IVS2 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 38 52 2 2 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
METTL15 METTL15 A6NJ78 12S rRNA N4-methylcytidine (m4C) methyltransferase chr11 Not Cancer Driver No 1 hippie, biogrid 46 92 14 14 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie, biogrid 110 101 8 8 0
MRPL2 MRPL2 Q5T653 39S ribosomal protein L2, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 43 132 17 17 0
MRPL36 MRPL36 Q9P0J6 39S ribosomal protein L36, mitochondrial chr5 Not Cancer Driver No 1 biogrid 12 4 0 0 0
MRPL37_ENST00000360840 MRPL37 Q9BZE1 39S ribosomal protein L37, mitochondrial chr1 Not Cancer Driver No 1 biogrid 44 36 5 5 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 Not Cancer Driver No 1 hippie 28 105 13 13 0
MRPS11 MRPS11 P82912 28S ribosomal protein S11, mitochondrial chr15 Not Cancer Driver No 2 intact, hippie, biogrid 23 114 12 12 0
MRPS15 MRPS15 P82914 28S ribosomal protein S15, mitochondrial chr1 Not Cancer Driver No 2 intact, hippie, biogrid 35 72 7 7 0
MRPS17 MRPS17 Q9Y2R5 28S ribosomal protein S17, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 14 9 3 3 0
MRPS18B MRPS18B Q9Y676 28S ribosomal protein S18b, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 31 112 12 12 0
MRPS18C MRPS18C Q9Y3D5 28S ribosomal protein S18c, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 16 5 1 1 0
MRPS2 MRPS2 Q9Y399 28S ribosomal protein S2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 32 57 6 6 3
MRPS23 MRPS23 Q9Y3D9 28S ribosomal protein S23, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 21 58 6 6 1
MRPS24 MRPS24 Q96EL2 28S ribosomal protein S24, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 1 0 0 0
MRPS25 MRPS25 P82663 28S ribosomal protein S25, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 24 38 5 5 1
MRPS26 MRPS26 Q9BYN8 28S ribosomal protein S26, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 18 102 6 6 0
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 Not Cancer Driver No 2 intact, hippie, biogrid 46 51 7 7 0
MRPS31 MRPS31 Q92665 28S ribosomal protein S31, mitochondrial chr13 Not Cancer Driver No 3 hippie, biogrid 46 231 28 28 0
MRPS34_ENST00000397375 MRPS34 P82930 28S ribosomal protein S34, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 13 56 2 2 1
MRPS36 MRPS36 P82909 Alpha-ketoglutarate dehydrogenase component 4 chr5 Not Cancer Driver No 1 intact 12 103 12 12 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 biogrid 52 157 20 20 0
MRPS6 MRPS6 P82932 28S ribosomal protein S6, mitochondrial chr21 Not Cancer Driver No 1 hippie, biogrid 17 13 1 1 0
MRPS9 MRPS9 P82933 28S ribosomal protein S9, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 49 75 9 9 0
MTERF3 MTERF3 Q96E29 Transcription termination factor 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 53 62 5 5 0
MTIF2_ENST00000403721 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 101 112 9 9 0
MTIF3_ENST00000381120 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 26 180 19 19 0
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 hippie, biogrid 19 70 13 13 0
NDUFAF3 NDUFAF3 Q9BU61 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 chr3 Not Cancer Driver No 1 hippie, biogrid 20 33 3 3 3
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 58 49 5 5 4
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
PADI4 PADI4 Q9UM07 Protein-arginine deiminase type-4 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 115 114 23 23 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 biogrid 61 40 5 5 9
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRR3 PRR3 P79522 Proline-rich protein 3 chr6 Not Cancer Driver No 1 hippie, biogrid 11 165 10 10 0
PRSS35 PRSS35 Q8N3Z0 Inactive serine protease 35 chr6 Not Cancer Driver No 1 intact, hippie 97 115 29 29 0
PSMC1 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 Not Cancer Driver No 1 biogrid 36 165 10 10 0
RBM42 RBM42 Q9BTD8 RNA-binding protein 42 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 78 338 48 48 0
RBMS2 RBMS2 Q15434 RNA-binding motif, single-stranded-interacting protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 53 265 38 38 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 hippie, biogrid 46 9 3 3 4
RPL35 RPL35 P42766 60S ribosomal protein L35 chr9 Not Cancer Driver No 1 hippie, biogrid 12 65 9 9 0
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 41 159 24 24 0
RPLP2_ENST00000530797 RPLP2 P05387 60S acidic ribosomal protein P2 chr11 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
RPS21 RPS21 P63220 40S ribosomal protein S21 chr20 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 1 hippie, biogrid 23 34 5 5 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SLIRP SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 41 3 3 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 intact, hippie 271 1573 232 232 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SRP14 SRP14 P37108 Signal recognition particle 14 kDa protein chr15 Not Cancer Driver No 1 hippie, biogrid 10 74 8 8 0
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 41 198 34 34 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 Census Yes 1 hippie, biogrid 31 125 27 27 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 69 259 49 49 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 1 intact, hippie 122 516 93 93 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 25 110 15 15 1
TRA2A TRA2A Q13595 Transformer-2 protein homolog alpha chr7 Not Cancer Driver No 1 hippie, biogrid 45 253 41 41 0
TRMT10B TRMT10B Q6PF06 tRNA methyltransferase 10 homolog B chr9 Not Cancer Driver No 3 intact, hippie, biogrid 35 75 13 13 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 37 73 7 7 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie 109 156 16 16 0
USP42 USP42 Q9H9J4 Ubiquitin carboxyl-terminal hydrolase 42 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 141 958 106 106 0
USP44_ENST00000537435 USP44 Q9H0E7 Ubiquitin carboxyl-terminal hydrolase 44 chr12 Census, Compendium Yes 1 intact, hippie, biogrid 94 114 14 14 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 biogrid 25 7 1 1 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 41 312 41 41 0
ZC3H3 ZC3H3 Q8IXZ2 Zinc finger CCCH domain-containing protein 3 chr8 Not Cancer Driver No 2 hippie, biogrid 130 750 99 99 0
ZNF460 ZNF460 Q14592 Zinc finger protein 460 chr19 Not Cancer Driver No 1 hippie, biogrid 83 131 16 16 0
ZNF467 ZNF467 Q7Z7K2 Zinc finger protein 467 chr7 Not Cancer Driver No 1 hippie, biogrid 75 345 37 37 0