Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AARS2 | AARS2 | Q5JTZ9 | Alanine--tRNA ligase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 123 | 203 | 25 | 25 | 5 |
ABCC2 | ABCC2 | Q92887 | ATP-binding cassette sub-family C member 2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 202 | 102 | 23 | 23 | 4 |
ABT1 | ABT1 | Q9ULW3 | Activator of basal transcription 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 157 | 30 | 30 | 0 |
ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 28 | 5 | 5 | 12 |
APOBEC3D | APOBEC3D | Q96AK3 | DNA dC->dU-editing enzyme APOBEC-3D | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 3 | 0 | 0 | 0 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
ATAD3A | ATAD3A | Q9NVI7 | ATPase family AAA domain-containing protein 3A | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 269 | 24 | 24 | 2 |
AUH | AUH | Q13825 | Methylglutaconyl-CoA hydratase, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 29 | 0 | 0 | 1 |
AURKAIP1_ENST00000321751 | AURKAIP1 | Q9NWT8 | Aurora kinase A-interacting protein | chr1 | Not Cancer Driver | No | 1 | hippie | 18 | 104 | 8 | 8 | 0 |
AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 178 | 21 | 21 | 0 |
BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BTRC | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | Not Cancer Driver | No | 1 | hippie | 80 | 45 | 4 | 4 | 0 |
C17orf80_ENST00000535032 | C17orf80 | Q9BSJ5 | Uncharacterized protein C17orf80 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 455 | 53 | 53 | 0 |
C19orf70_ENST00000309324 | MICOS13 | Q5XKP0 | MICOS complex subunit MIC13 | chr19 | Not Cancer Driver | No | 1 | hippie | 12 | 3 | 0 | 0 | 0 |
C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 103 | 6 | 6 | 2 |
C8orf82 | C8orf82 | Q6P1X6 | UPF0598 protein C8orf82 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 11 | 0 | 0 | 0 |
CENPE | CENPE | Q02224 | Centromere-associated protein E | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 343 | 1620 | 228 | 228 | 2 |
CGAS | CGAS | Q8N884 | Cyclic GMP-AMP synthase | chr6 | Not Cancer Driver | No | 1 | hippie | 50 | 173 | 7 | 7 | 0 |
CHCHD1 | CHCHD1 | Q96BP2 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 67 | 8 | 8 | 0 |
CIAO1 | CIAO1 | O76071 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 20 | 2 | 2 | 0 |
COP1 | COP1 | Q8NHY2 | E3 ubiquitin-protein ligase COP1 | chr1 | Not Cancer Driver | No | 1 | intact | 106 | 147 | 11 | 11 | 0 |
COX8A | COX8A | P10176 | Cytochrome c oxidase subunit 8A, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 1 | 0 | 0 | 0 |
CS | CS | O75390 | Citrate synthase, mitochondrial | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 50 | 13 | 2 | 2 | 0 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 123 | 167 | 23 | 23 | 3 |
DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
DDX28 | DDX28 | Q9NUL7 | Probable ATP-dependent RNA helicase DDX28 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 127 | 3 | 3 | 0 |
DNAJC15 | DNAJC15 | Q9Y5T4 | DnaJ homolog subfamily C member 15 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 25 | 4 | 4 | 0 |
DUSP11 | DUSP11 | O75319 | RNA/RNP complex-1-interacting phosphatase | chr2 | Not Cancer Driver | No | 1 | hippie | 42 | 157 | 12 | 12 | 0 |
DYRK2 | DYRK2 | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 294 | 39 | 39 | 0 |
ECH1 | ECH1 | Q13011 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 23 | 2 | 2 | 0 |
EMC2 | EMC2 | Q15006 | ER membrane protein complex subunit 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 48 | 29 | 3 | 3 | 0 |
ENG | ENG | P17813 | Endoglin | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 114 | 15 | 15 | 32 |
ERLEC1 | ERLEC1 | Q96DZ1 | Endoplasmic reticulum lectin 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 134 | 17 | 17 | 0 |
EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 176 | 15 | 15 | 0 |
FAHD1_ENST00000427358 | FAHD1 | Q6P587 | Acylpyruvase FAHD1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 12 | 0 | 0 | 0 |
FASTKD2_ENST00000402774 | FASTKD2 | Q9NYY8 | FAST kinase domain-containing protein 2, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 30 | 2 | 2 | 0 |
FASTKD3 | FASTKD3 | Q14CZ7 | FAST kinase domain-containing protein 3, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 6 | 1 | 1 | 0 |
FASTKD5 | FASTKD5 | Q7L8L6 | FAST kinase domain-containing protein 5, mitochondrial | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 94 | 8 | 8 | 0 |
FOXB1 | FOXB1 | Q99853 | Forkhead box protein B1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 114 | 5 | 5 | 0 |
FOXL2 | FOXL2 | P58012 | Forkhead box protein L2 | chr3 | Census, Compendium | Yes | 1 | intact, hippie | 39 | 257 | 20 | 20 | 26 |
GADD45GIP1 | GADD45GIP1 | Q8TAE8 | Growth arrest and DNA damage-inducible proteins-interacting protein 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 19 | 193 | 19 | 19 | 0 |
GFM1_ENST00000486715 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 79 | 7 | 7 | 4 |
GFM2_ENST00000509430 | GFM2 | Q969S9 | Ribosome-releasing factor 2, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 100 | 10 | 10 | 2 |
GRSF1 | GRSF1 | Q12849 | G-rich sequence factor 1 | chr4 | Not Cancer Driver | No | 2 | hippie, biogrid | 49 | 147 | 20 | 20 | 0 |
HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 40 | 352 | 40 | 40 | 0 |
HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 29 | 2 | 2 | 0 |
HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | Not Cancer Driver | No | 1 | hippie | 70 | 290 | 58 | 58 | 4 |
HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 504 | 45 | 45 | 0 |
HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 25 | 6 | 6 | 0 |
HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 82 | 6 | 6 | 2 |
HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | Compendium | Yes | 1 | hippie | 44 | 127 | 9 | 9 | 2 |
ILF2 | ILF2 | Q12905 | Interleukin enhancer-binding factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 92 | 9 | 9 | 0 |
IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 7 | 7 | 0 |
KLF15 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | Not Cancer Driver | No | 1 | hippie | 66 | 273 | 48 | 48 | 0 |
LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 350 | 44 | 44 | 0 |
LEO1 | LEO1 | Q8WVC0 | RNA polymerase-associated protein LEO1 | chr15 | Not Cancer Driver | No | 1 | biogrid | 74 | 611 | 69 | 69 | 0 |
LIN28A_ENST00000254231 | LIN28A | Q9H9Z2 | Protein lin-28 homolog A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 86 | 12 | 12 | 0 |
LRPPRC | LRPPRC | P42704 | Leucine-rich PPR motif-containing protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 18 | 2 | 2 | 1 |
LTN1_ENST00000361371 | LTN1 | O94822 | E3 ubiquitin-protein ligase listerin | chr21 | Not Cancer Driver | No | 1 | hippie | 192 | 124 | 23 | 23 | 0 |
MALSU1 | MALSU1 | Q96EH3 | Mitochondrial assembly of ribosomal large subunit protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 34 | 0 | 0 | 0 |
MAST1 | MAST1 | Q9Y2H9 | Microtubule-associated serine/threonine-protein kinase 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 204 | 1078 | 119 | 119 | 1 |
MCU | MCU | Q8NE86 | Calcium uniporter protein, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 13 | 0 | 0 | 0 |
MCUB | MCUB | Q9NWR8 | Calcium uniporter regulatory subunit MCUb, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 24 | 1 | 1 | 0 |
MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 8 | 1 | 1 | 3 |
MED24_ENST00000394128 | MED24 | O75448 | Mediator of RNA polymerase II transcription subunit 24 | chr17 | Not Cancer Driver | No | 1 | biogrid | 101 | 76 | 0 | 0 | 0 |
MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | Not Cancer Driver | No | 1 | hippie | 76 | 446 | 42 | 42 | 0 |
METTL15 | METTL15 | A6NJ78 | 12S rRNA N4-methylcytidine (m4C) methyltransferase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 92 | 14 | 14 | 0 |
METTL17_ENST00000339374 | METTL17 | Q9H7H0 | Methyltransferase-like protein 17, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 95 | 16 | 16 | 0 |
MGST3 | MGST3 | O14880 | Microsomal glutathione S-transferase 3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 0 | 0 | 0 | 0 |
MRPL10_ENST00000351111 | MRPL10 | Q7Z7H8 | 39S ribosomal protein L10, mitochondrial | chr17 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 37 | 40 | 6 | 6 | 0 |
MRPL11 | MRPL11 | Q9Y3B7 | 39S ribosomal protein L11, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 12 | 1 | 1 | 0 |
MRPL12 | MRPL12 | P52815 | 39S ribosomal protein L12, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 22 | 6 | 6 | 1 |
MRPL13 | MRPL13 | Q9BYD1 | 39S ribosomal protein L13, mitochondrial | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 28 | 10 | 1 | 1 | 0 |
MRPL17 | MRPL17 | Q9NRX2 | 39S ribosomal protein L17, mitochondrial | chr11 | Not Cancer Driver | No | 1 | intact | 13 | 39 | 2 | 2 | 0 |
MRPL18 | MRPL18 | Q9H0U6 | 39S ribosomal protein L18, mitochondrial | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 26 | 35 | 2 | 2 | 0 |
MRPL19_ENST00000409374 | MRPL19 | P49406 | 39S ribosomal protein L19, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 63 | 4 | 4 | 0 |
MRPL2 | MRPL2 | Q5T653 | 39S ribosomal protein L2, mitochondrial | chr6 | Not Cancer Driver | No | 3 | hippie, biogrid | 43 | 132 | 17 | 17 | 0 |
MRPL20 | MRPL20 | Q9BYC9 | 39S ribosomal protein L20, mitochondrial | chr1 | Not Cancer Driver | No | 1 | intact | 20 | 0 | 0 | 0 | 0 |
MRPL21 | MRPL21 | Q7Z2W9 | 39S ribosomal protein L21, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 20 | 0 | 0 | 0 |
MRPL22 | MRPL22 | Q9NWU5 | 39S ribosomal protein L22, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 28 | 2 | 2 | 0 |
MRPL23 | MRPL23 | Q16540 | 39S ribosomal protein L23, mitochondrial | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 29 | 68 | 12 | 12 | 0 |
MRPL27 | MRPL27 | Q9P0M9 | 39S ribosomal protein L27, mitochondrial | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 16 | 35 | 2 | 2 | 0 |
MRPL28_ENST00000389675 | MRPL28 | Q13084 | 39S ribosomal protein L28, mitochondrial | chr16 | Not Cancer Driver | No | 5 | hippie, biogrid | 21 | 52 | 3 | 3 | 0 |
MRPL30 | MRPL30 | Q8TCC3 | 39S ribosomal protein L30, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 75 | 11 | 11 | 0 |
MRPL33 | MRPL33 | O75394 | 39S ribosomal protein L33, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 0 | 0 | 0 | 0 |
MRPL37_ENST00000360840 | MRPL37 | Q9BZE1 | 39S ribosomal protein L37, mitochondrial | chr1 | Not Cancer Driver | No | 5 | hippie, biogrid | 44 | 36 | 5 | 5 | 0 |
MRPL38 | MRPL38 | Q96DV4 | 39S ribosomal protein L38, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 88 | 13 | 13 | 0 |
MRPL39_ENST00000352957 | MRPL39 | Q9NYK5 | 39S ribosomal protein L39, mitochondrial | chr21 | Not Cancer Driver | No | 4 | hippie, biogrid | 41 | 38 | 6 | 6 | 0 |
MRPL40 | MRPL40 | Q9NQ50 | 39S ribosomal protein L40, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 104 | 9 | 9 | 0 |
MRPL41 | MRPL41 | Q8IXM3 | 39S ribosomal protein L41, mitochondrial | chr9 | Not Cancer Driver | No | 3 | hippie, biogrid | 18 | 23 | 1 | 1 | 0 |
MRPL42 | MRPL42 | Q9Y6G3 | 39S ribosomal protein L42, mitochondrial | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 52 | 5 | 5 | 0 |
MRPL44 | MRPL44 | Q9H9J2 | 39S ribosomal protein L44, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 45 | 2 | 2 | 1 |
MRPL46 | MRPL46 | Q9H2W6 | 39S ribosomal protein L46, mitochondrial | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 24 | 58 | 0 | 0 | 0 |
MRPL47 | MRPL47 | Q9HD33 | 39S ribosomal protein L47, mitochondrial | chr3 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 44 | 34 | 7 | 7 | 0 |
MRPL4_ENST00000307422 | MRPL4 | Q9BYD3 | 39S ribosomal protein L4, mitochondrial | chr19 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 29 | 105 | 14 | 14 | 0 |
MRPL50 | MRPL50 | Q8N5N7 | 39S ribosomal protein L50, mitochondrial | chr9 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 27 | 3 | 0 | 0 | 0 |
MRPL51 | MRPL51 | Q4U2R6 | 39S ribosomal protein L51, mitochondrial | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
MRPL52 | MRPL52 | Q86TS9 | 39S ribosomal protein L52, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 75 | 7 | 7 | 0 |
MRPL53 | MRPL53 | Q96EL3 | 39S ribosomal protein L53, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 22 | 1 | 1 | 0 |
MRPL58 | MRPL58 | Q14197 | Peptidyl-tRNA hydrolase ICT1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 28 | 105 | 13 | 13 | 0 |
MRPL9 | MRPL9 | Q9BYD2 | 39S ribosomal protein L9, mitochondrial | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 24 | 54 | 3 | 3 | 0 |
MRPS10 | MRPS10 | P82664 | 28S ribosomal protein S10, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 22 | 3 | 3 | 0 |
MRPS12_ENST00000402029 | MRPS12 | O15235 | 28S ribosomal protein S12, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 59 | 11 | 11 | 0 |
MRPS18A | MRPS18A | Q9NVS2 | 39S ribosomal protein S18a, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 82 | 5 | 5 | 0 |
MRPS26 | MRPS26 | Q9BYN8 | 28S ribosomal protein S26, mitochondrial | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 102 | 6 | 6 | 0 |
MRPS30 | MRPS30 | Q9NP92 | 39S ribosomal protein S30, mitochondrial | chr5 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 54 | 53 | 10 | 10 | 0 |
MRPS5 | MRPS5 | P82675 | 28S ribosomal protein S5, mitochondrial | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 157 | 20 | 20 | 0 |
MRRF | MRRF | Q96E11 | Ribosome-recycling factor, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 118 | 9 | 9 | 0 |
MTERF3 | MTERF3 | Q96E29 | Transcription termination factor 3, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 62 | 5 | 5 | 0 |
MTFMT | MTFMT | Q96DP5 | Methionyl-tRNA formyltransferase, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 56 | 3 | 3 | 3 |
MTG1 | MTG1 | Q9BT17 | Mitochondrial ribosome-associated GTPase 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 16 | 3 | 3 | 0 |
MTG2 | MTG2 | Q9H4K7 | Mitochondrial ribosome-associated GTPase 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 47 | 9 | 9 | 0 |
MTIF2_ENST00000403721 | MTIF2 | P46199 | Translation initiation factor IF-2, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 112 | 9 | 9 | 0 |
MTIF3_ENST00000381120 | MTIF3 | Q9H2K0 | Translation initiation factor IF-3, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 180 | 19 | 19 | 0 |
MTRF1 | MTRF1 | O75570 | Peptide chain release factor 1, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 71 | 9 | 9 | 0 |
MTRF1L | MTRF1L | Q9UGC7 | Peptide chain release factor 1-like, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 183 | 12 | 12 | 0 |
NDUFAB1_ENST00000007516 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 0 | 0 | 0 | 0 |
NGRN | NGRN | Q9NPE2 | Neugrin | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 215 | 21 | 21 | 0 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | Census, Compendium | Yes | 1 | hippie | 29 | 249 | 22 | 22 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
PDK1_ENST00000282077 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 50 | 10 | 10 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PMPCA | PMPCA | Q10713 | Mitochondrial-processing peptidase subunit alpha | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 23 | 3 | 3 | 4 |
PMPCB | PMPCB | O75439 | Mitochondrial-processing peptidase subunit beta | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 22 | 3 | 3 | 5 |
POLR3A | POLR3A | O14802 | DNA-directed RNA polymerase III subunit RPC1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 155 | 113 | 17 | 17 | 15 |
PRR3 | PRR3 | P79522 | Proline-rich protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 165 | 10 | 10 | 0 |
PSKH1 | PSKH1 | P11801 | Serine/threonine-protein kinase H1 | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 56 | 122 | 24 | 24 | 0 |
RAE1_ENST00000371242 | RAE1 | P78406 | mRNA export factor RAE1 | chr20 | Not Cancer Driver | No | 1 | intact | 64 | 73 | 11 | 11 | 0 |
RASA1 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | Compendium | Yes | 1 | hippie | 154 | 181 | 25 | 25 | 3 |
RBM4_ENST00000310092 | RBM4 | Q9BWF3 | RNA-binding protein 4 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 129 | 12 | 12 | 0 |
RBMS2 | RBMS2 | Q15434 | RNA-binding motif, single-stranded-interacting protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 265 | 38 | 38 | 0 |
RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 158 | 796 | 115 | 115 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
REST | REST | Q13127 | RE1-silencing transcription factor | chr4 | Not Cancer Driver | No | 1 | hippie | 142 | 868 | 113 | 113 | 4 |
RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
RIOX1 | RIOX1 | Q9H6W3 | Ribosomal oxygenase 1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 215 | 15 | 15 | 0 |
RPL10_ENST00000369817 | RPL10 | P27635 | 60S ribosomal protein L10 | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 46 | 9 | 3 | 3 | 4 |
RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 12 | 1 | 1 | 1 |
RPL13A | RPL13A | P40429 | 60S ribosomal protein L13a | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 33 | 2 | 2 | 0 |
RPL17_ENST00000579248 | RPL17 | P18621 | 60S ribosomal protein L17 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 97 | 14 | 14 | 0 |
RPL18 | RPL18 | Q07020 | 60S ribosomal protein L18 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 16 | 98 | 6 | 6 | 0 |
RPL19 | RPL19 | P84098 | 60S ribosomal protein L19 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 121 | 21 | 21 | 0 |
RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 114 | 13 | 13 | 0 |
RPL27A | RPL27A | P46776 | 60S ribosomal protein L27a | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 56 | 2 | 2 | 0 |
RPL32_ENST00000435983 | RPL32 | P62910 | 60S ribosomal protein L32 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 75 | 5 | 5 | 0 |
RPL35 | RPL35 | P42766 | 60S ribosomal protein L35 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 65 | 9 | 9 | 0 |
RPL36AL | RPL36AL | Q969Q0 | 60S ribosomal protein L36a-like | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 64 | 7 | 7 | 0 |
RPL37 | RPL37 | P61927 | 60S ribosomal protein L37 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 83 | 10 | 10 | 0 |
RPL6 | RPL6 | Q02878 | 60S ribosomal protein L6 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 41 | 159 | 24 | 24 | 0 |
RPL8_ENST00000528957 | RPL8 | P62917 | 60S ribosomal protein L8 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 115 | 17 | 17 | 0 |
RPS11 | RPS11 | P62280 | 40S ribosomal protein S11 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 6 | 0 | 0 | 0 |
RPS15_ENST00000592588 | RPS15 | P62841 | 40S ribosomal protein S15 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 59 | 7 | 7 | 0 |
RPS18 | RPS18 | P62269 | 40S ribosomal protein S18 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 27 | 8 | 8 | 0 |
RPS5_ENST00000601521 | RPS5 | P46782 | 40S ribosomal protein S5 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 40 | 8 | 8 | 0 |
RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 38 | 150 | 25 | 25 | 0 |
RPS6KA5 | RPS6KA5 | O75582 | Ribosomal protein S6 kinase alpha-5 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 187 | 18 | 18 | 0 |
RPS8 | RPS8 | P62241 | 40S ribosomal protein S8 | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 23 | 81 | 7 | 7 | 0 |
RPS9_ENST00000391752 | RPS9 | P46781 | 40S ribosomal protein S9 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 34 | 5 | 5 | 0 |
RPUSD4 | RPUSD4 | Q96CM3 | Pseudouridylate synthase RPUSD4, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 97 | 15 | 15 | 0 |
SH3GL3_ENST00000427482 | SH3GL3 | Q99963 | Endophilin-A3 | chr15 | Not Cancer Driver | No | 1 | hippie | 88 | 83 | 23 | 23 | 0 |
SLC25A12 | SLC25A12 | O75746 | Calcium-binding mitochondrial carrier protein Aralar1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 110 | 21 | 7 | 7 | 2 |
SMYD3 | SMYD3 | Q9H7B4 | Histone-lysine N-methyltransferase SMYD3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 59 | 2 | 0 | 0 | 0 |
SNIP1 | SNIP1 | Q8TAD8 | Smad nuclear-interacting protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 58 | 285 | 40 | 40 | 1 |
SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 416 | 37 | 37 | 0 |
SORT1 | SORT1 | Q99523 | Sortilin | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 69 | 110 | 2 | 2 | 0 |
SRSF3_ENST00000620941 | SRSF3 | P84103 | Serine/arginine-rich splicing factor 3 | chr6 | Census | Yes | 1 | hippie, biogrid | 31 | 125 | 27 | 27 | 0 |
SRSF4 | SRSF4 | Q08170 | Serine/arginine-rich splicing factor 4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 409 | 55 | 55 | 0 |
SRSF5_ENST00000557154 | SRSF5 | Q13243 | Serine/arginine-rich splicing factor 5 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 189 | 40 | 40 | 0 |
SSBP1_ENST00000484178 | SSBP1 | Q04837 | Single-stranded DNA-binding protein, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 0 | 0 | 0 | 6 |
STK32C | STK32C | Q86UX6 | Serine/threonine-protein kinase 32C | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 172 | 10 | 10 | 0 |
TACO1 | TACO1 | Q9BSH4 | Translational activator of cytochrome c oxidase 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 111 | 2 | 2 | 0 |
TBRG4_ENST00000494076 | TBRG4 | Q969Z0 | FAST kinase domain-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 60 | 2 | 2 | 0 |
TEFM | TEFM | Q96QE5 | Transcription elongation factor, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 26 | 5 | 5 | 0 |
TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | Not Cancer Driver | No | 1 | intact | 219 | 126 | 22 | 22 | 10 |
TFAM | TFAM | Q00059 | Transcription factor A, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 110 | 15 | 15 | 1 |
TMEM177 | TMEM177 | Q53S58 | Transmembrane protein 177 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 0 | 0 | 0 | 0 |
TMEM70 | TMEM70 | Q9BUB7 | Transmembrane protein 70, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 24 | 4 | 4 | 1 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TRAP1 | TRAP1 | Q12931 | Heat shock protein 75 kDa, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 110 | 11 | 11 | 0 |
TRIM14 | TRIM14 | Q14142 | Tripartite motif-containing protein 14 | chr9 | Not Cancer Driver | No | 1 | hippie | 36 | 93 | 7 | 7 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TRMT61B | TRMT61B | Q9BVS5 | tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 123 | 10 | 10 | 0 |
TRUB2 | TRUB2 | O95900 | Pseudouridylate synthase TRUB2, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 73 | 7 | 7 | 0 |
TSFM_ENST00000454289 | TSFM | P43897 | Elongation factor Ts, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 74 | 7 | 7 | 2 |
TSR1 | TSR1 | Q2NL82 | Pre-rRNA-processing protein TSR1 homolog | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 332 | 32 | 32 | 0 |
TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | Not Cancer Driver | No | 3 | hippie, biogrid | 51 | 50 | 3 | 3 | 1 |
YBX1 | YBX1 | P67809 | Y-box-binding protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 312 | 41 | 41 | 0 |
YBX2 | YBX2 | Q9Y2T7 | Y-box-binding protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 342 | 46 | 46 | 0 |
ZC3HAV1 | ZC3HAV1 | Q7Z2W4 | Zinc finger CCCH-type antiviral protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 344 | 63 | 63 | 0 |
ZNF467 | ZNF467 | Q7Z7K2 | Zinc finger protein 467 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 345 | 37 | 37 | 0 |
ZNF574_ENST00000359044 | ZNF574 | Q6ZN55 | Zinc finger protein 574 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 410 | 51 | 51 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|