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MPZL1 ,MPZL1 ,O95297
  • Uniprot Accession= O95297
  • Ensembl Transcript= ENST00000359523.6
  • Uniprot Name= MPZL1
  • Name= Myelin protein zero-like protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 30
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 108
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABTB2 ABTB2 Q8N961 Ankyrin repeat and BTB/POZ domain-containing protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 95 215 20 20 0
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 73 29 5 5 0
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 100 56 13 13 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 46 85 7 7 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 1 hippie 85 330 52 52 0
BTNL9 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 69 87 4 4 0
C11orf52 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 15 108 12 12 0
C6orf136_ENST00000376473 C6orf136 Q5SQH8 Uncharacterized protein C6orf136 chr6 Not Cancer Driver No 1 hippie, biogrid 39 119 6 6 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 27 62 8 8 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 Not Cancer Driver No 1 hippie, biogrid 144 186 33 33 2
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 Not Cancer Driver No 1 hippie, biogrid 35 22 4 4 0
CLGN_ENST00000414773 CLGN O14967 Calmegin chr4 Not Cancer Driver No 1 hippie, biogrid 86 255 36 36 0
CPA2 CPA2 P48052 Carboxypeptidase A2 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 62 26 2 2 0
CPA5_ENST00000461828 CPA5 Q8WXQ8 Carboxypeptidase A5 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 79 40 4 4 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 intact, hippie 38 160 25 25 0
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX Census Yes 1 hippie, biogrid 54 62 3 3 0
CTDSPL CTDSPL O15194 CTD small phosphatase-like protein chr3 Not Cancer Driver No 1 intact, hippie 32 60 4 4 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 37 3 0 0 1
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
CYP2S1 CYP2S1 Q96SQ9 Cytochrome P450 2S1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 75 46 10 10 0
DIRAS3_ENST00000646789 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie, biogrid 38 21 3 3 0
DOK7 DOK7 Q18PE1 Protein Dok-7 chr4 Not Cancer Driver No 1 hippie 52 286 27 27 19
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EVA1B EVA1B Q9NVM1 Protein eva-1 homolog B chr1 Not Cancer Driver No 1 hippie, biogrid 18 118 9 9 0
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 Not Cancer Driver No 1 intact, hippie 34 23 0 0 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FCGRT_ENST00000426395 FCGRT P55899 IgG receptor FcRn large subunit p51 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 54 65 12 12 0
FHL3 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 hippie 33 0 0 0 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 Not Cancer Driver No 1 intact, hippie, biogrid 67 53 10 10 3
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 Not Cancer Driver No 1 hippie, biogrid 57 33 5 5 19
GGT7 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 77 170 14 14 0
GPRC5D GPRC5D Q9NZD1 G-protein coupled receptor family C group 5 member D chr12 Not Cancer Driver No 1 hippie, biogrid 32 32 1 1 0
GYPA_ENST00000360771 GYPA P02724 Glycophorin-A chr4 Not Cancer Driver No 1 hippie, biogrid 46 94 31 31 0
HCCS HCCS P53701 Holocytochrome c-type synthase chrX Not Cancer Driver No 3 hippie, biogrid 48 117 25 25 1
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie, biogrid 107 16 4 4 18
HSD17B1_ENST00000585807 HSD17B1 P14061 17-beta-hydroxysteroid dehydrogenase type 1 chr17 Not Cancer Driver No 1 hippie, biogrid 48 59 28 28 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie, biogrid 149 251 52 52 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 109 287 36 36 9
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 Not Cancer Driver No 2 intact, hippie, biogrid 55 43 3 3 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 103 49 11 11 12
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 Not Cancer Driver No 1 intact, hippie 150 844 104 104 5
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 15 133 6 6 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 3 hippie, biogrid 54 65 16 16 0
LIPF_ENST00000238983 LIPF P07098 Gastric triacylglycerol lipase chr10 Not Cancer Driver No 3 intact, hippie, biogrid 74 0 0 0 0
LY6G5B LY6G5B Q8NDX9 Lymphocyte antigen 6 complex locus protein G5b chr6 Not Cancer Driver No 1 hippie, biogrid 20 2 0 0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 12 46 3 3 0
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 Not Cancer Driver No 1 intact, hippie 59 264 47 47 0
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 hippie, biogrid 37 45 3 3 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NHLRC3 NHLRC3 Q5JS37 NHL repeat-containing protein 3 chr13 Not Cancer Driver No 1 hippie, biogrid 40 7 0 0 0
NOXRED1 NOXRED1 Q6NXP6 NADP-dependent oxidoreductase domain-containing protein 1 chr14 Not Cancer Driver No 3 hippie, biogrid 50 4 1 1 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 227 1008 107 107 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie, biogrid 50 49 3 3 0
PLAC9 PLAC9 Q5JTB6 Placenta-specific protein 9 chr10 Not Cancer Driver No 1 hippie, biogrid 10 46 6 6 0
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 1 hippie, biogrid 63 102 16 16 0
PRPH2 PRPH2 P23942 Peripherin-2 chr6 Not Cancer Driver No 1 hippie, biogrid 54 35 2 2 44
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 4 intact, hippie, biogrid 129 260 38 38 60
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 52 19 2 2 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
SAAL1 SAAL1 Q96ER3 Protein SAAL1 chr11 Not Cancer Driver No 1 hippie, biogrid 46 75 11 11 0
SFTPC SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 2 hippie, biogrid 21 19 2 2 5
SIGLECL1 SIGLECL1 Q8N7X8 SIGLEC family-like protein 1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 56 35 14 14 0
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 77 116 11 11 9
SPACA1 SPACA1 Q9HBV2 Sperm acrosome membrane-associated protein 1 chr6 Not Cancer Driver No 3 hippie, biogrid 65 79 9 9 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 1
TENT4B TENT4B Q8NDF8-5 Isoform 5 of Terminal nucleotidyltransferase 4B chr16 Not Cancer Driver No 1 hippie 62 409 30 30 0
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM206_ENST00000261455 PACC1 Q9H813 Proton-activated chloride channel chr1 Not Cancer Driver No 1 intact 51 32 5 5 0
TMEM30B TMEM30B Q3MIR4 Cell cycle control protein 50B chr14 Not Cancer Driver No 2 hippie, biogrid 18 17 0 0 0
TMEM65 TMEM65 Q6PI78 Transmembrane protein 65 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 23 50 1 1 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TNPO2 TNPO2 O14787 Transportin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 99 76 10 10 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 Not Cancer Driver No 1 hippie 38 81 12 12 0
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie, biogrid 134 276 78 78 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie, biogrid 47 71 13 13 0
TRPC4AP TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 Not Cancer Driver No 1 intact, hippie, biogrid 84 70 7 7 0
TSPAN31 TSPAN31 Q12999 Tetraspanin-31 chr12 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
VAC14 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 97 116 19 19 3
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 41 10 2 2 0