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MPL ,MPL ,P40238
  • Uniprot Accession= P40238
  • Ensembl Transcript= ENST00000372470.8
  • Uniprot Name= MPL
  • Name= Thrombopoietin receptor
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 26
  • Number of Interaction partner in hippie: 38
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACOT9_ENST00000336430 ACOT9 Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 45 45 3 3 0
ADGRL3 ADGRL3 Q9HAR2 Adhesion G protein-coupled receptor L3 chr4 Not Cancer Driver No 1 hippie 440 517 130 130 0
ALCAM ALCAM Q13740 CD166 antigen chr3 Not Cancer Driver No 1 hippie, biogrid 89 96 19 19 0
ALX1 ALX1 Q15699 ALX homeobox protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 75 190 48 48 0
ANKRA2 ANKRA2 Q9H9E1 Ankyrin repeat family A protein 2 chr5 Not Cancer Driver No 1 hippie 31 97 11 11 0
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 130 147 16 16 0
ATXN2L_ENST00000336783 ATXN2L Q8WWM7 Ataxin-2-like protein chr16 Not Cancer Driver No 1 hippie 135 1000 131 131 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 Not Cancer Driver No 1 hippie, biogrid 92 24 2 2 0
CCDC51 CCDC51 Q96ER9 Mitochondrial potassium channel chr3 Not Cancer Driver No 1 hippie, biogrid 51 137 21 21 0
CISD2 CISD2 Q8N5K1 CDGSH iron-sulfur domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 11 7 0 0 0
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 Not Cancer Driver No 1 hippie, biogrid 45 49 6 6 2
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 444 223 35 35 1
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 Not Cancer Driver No 1 hippie, biogrid 149 410 51 51 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie, biogrid 211 829 117 117 9
FAAP100 FAAP100 Q0VG06 Fanconi anemia core complex-associated protein 100 chr17 Not Cancer Driver No 1 hippie 93 207 31 31 0
FAM171A2 FAM171A2 A8MVW0 Protein FAM171A2 chr17 Not Cancer Driver No 1 hippie, biogrid 13 478 4 4 0
GOLGA7_ENST00000518270 GOLGA7 Q7Z5G4 Golgin subfamily A member 7 chr8 Not Cancer Driver No 1 hippie, biogrid 8 6 0 0 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 27 112 17 17 0
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 Not Cancer Driver No 1 hippie 69 1112 57 57 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
KCNT2 KCNT2 Q6UVM3 Potassium channel subfamily T member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 353 245 89 89 1
LRP12 LRP12 Q9Y561 Low-density lipoprotein receptor-related protein 12 chr8 Not Cancer Driver No 1 hippie, biogrid 199 240 54 54 0
NSUN3 NSUN3 Q9H649 tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
PAX3_ENST00000350526 PAX3 P23760 Paired box protein Pax-3 chr2 Census Yes 1 hippie, biogrid 113 391 95 95 28
PDXP PDXP Q96GD0 Chronophin chr22 Not Cancer Driver No 1 hippie, biogrid 14 38 4 4 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie 129 260 38 38 60
RETSAT RETSAT Q6NUM9 All-trans-retinol 13,14-reductase chr2 Not Cancer Driver No 1 hippie, biogrid 98 25 5 5 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 353 1122 234 234 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 Census, Compendium Yes 1 hippie 22 66 3 3 2
THPO THPO P40225 Thrombopoietin chr3 Not Cancer Driver No 1 hippie 63 163 25 25 0
TSC2 TSC2 P49815 Tuberin chr16 Census, Compendium Yes 1 hippie, biogrid 192 563 50 50 53
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 1 hippie, biogrid 148 213 29 29 0
TYW1 TYW1 Q9NV66 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 chr7 Not Cancer Driver No 1 hippie, biogrid 102 152 21 21 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
ZNF282 ZNF282 Q9UDV7 Zinc finger protein 282 chr7 Not Cancer Driver No 1 hippie, biogrid 89 440 43 43 0