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MPC2 ,MPC2 ,O95563
  • Uniprot Accession= O95563
  • Ensembl Transcript= ENST00000367846.8
  • Uniprot Name= MPC2
  • Name= Mitochondrial pyruvate carrier 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 26
  • Number of Interaction partner in hippie: 54
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADAM18 ADAM18 Q9Y3Q7 Disintegrin and metalloproteinase domain-containing protein 18 chr8 Not Cancer Driver No 1 hippie, biogrid 224 4 2 2 0
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 Not Cancer Driver No 1 intact, hippie 12 9 1 1 0
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 248 360 82 82 0
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 Not Cancer Driver No 1 hippie 7 14 1 1 0
C15orf48_ENST00000396650 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 14 10 1 1 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 Not Cancer Driver No 1 hippie 8 97 4 4 4
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 Not Cancer Driver No 1 intact, hippie 19 23 1 1 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 Not Cancer Driver No 1 hippie, biogrid 34 57 8 8 0
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie 62 54 8 8 1
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie 67 212 23 23 7
DR1_ENST00000370267 DR1 Q01658 Protein Dr1 chr1 Not Cancer Driver No 1 hippie 21 84 12 12 0
EEF1D_ENST00000395119 EEF1D P29692 Elongation factor 1-delta chr8 Not Cancer Driver No 1 intact, hippie 40 153 22 22 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 1 hippie, biogrid 29 125 8 8 1
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 56 20 3 3 0
FTL FTL P02792 Ferritin light chain chr19 Not Cancer Driver No 1 hippie, biogrid 19 36 7 7 2
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 Not Cancer Driver No 1 intact, hippie 109 195 22 22 0
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 Not Cancer Driver No 1 intact 37 210 35 35 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
IFNGR2_ENST00000290219 IFNGR2 P38484 Interferon gamma receptor 2 chr21 Not Cancer Driver No 1 hippie, biogrid 36 18 2 2 5
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAGEA8_ENST00000542674 MAGEA8 P43361 Melanoma-associated antigen 8 chrX Not Cancer Driver No 1 hippie, biogrid 65 112 19 19 0
MINOS1 MICOS10 Q5TGZ0 MICOS complex subunit MIC10 chr1 Not Cancer Driver No 1 intact, hippie 5 0 0 0 0
MPC1 MPC1 Q9Y5U8 Mitochondrial pyruvate carrier 1 chr6 Not Cancer Driver No 5 intact, hippie, biogrid 8 0 0 0 2
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 Not Cancer Driver No 1 intact, hippie 13 0 0 0 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 1 hippie 14 46 4 4 2
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie, biogrid 146 211 31 31 0
OGFOD3_ENST00000313056 OGFOD3 Q6PK18 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 52 51 5 5 0
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 49 28 5 5 0
RAB5IF_ENST00000373852 RAB5IF Q9BUV8 Respirasome Complex Assembly Factor 1 chr20 Not Cancer Driver No 1 hippie 7 13 0 0 0
RHBDD2 RHBDD2 Q6NTF9 Rhomboid domain-containing protein 2 chr7 Not Cancer Driver No 1 intact, hippie 48 120 23 23 0
RPLP1 RPLP1 P05386 60S acidic ribosomal protein P1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 6 45 2 2 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 48 187 30 30 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 31 29 1 1 0
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 Not Cancer Driver No 1 hippie, biogrid 105 23 7 7 1
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 Not Cancer Driver No 2 hippie, biogrid 69 17 4 4 1
SLC1A5 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 Not Cancer Driver No 1 hippie, biogrid 52 61 7 7 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 Not Cancer Driver No 1 hippie, biogrid 110 21 7 7 2
SLC39A12 SLC39A12 Q504Y0 Zinc transporter ZIP12 chr10 Not Cancer Driver No 1 hippie, biogrid 210 89 29 29 0
SLC39A9 SLC39A9 Q9NUM3 Zinc transporter ZIP9 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 34 44 4 4 0
SLCO1B1 SLCO1B1 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 chr12 Not Cancer Driver No 1 hippie, biogrid 177 33 3 3 0
SNX1_ENST00000559844 SNX1 Q13596 Sorting nexin-1 chr15 Not Cancer Driver No 1 intact, hippie 61 214 25 25 0
SPG21_ENST00000433215 SPG21 Q9NZD8 Maspardin chr15 Not Cancer Driver No 1 hippie 31 13 1 1 0
SYT16 SYT16 Q17RD7 Synaptotagmin-16 chr14 Not Cancer Driver No 1 intact, hippie 178 394 113 113 0
TEX44 TEX44 Q53QW1 Testis-expressed protein 44 chr2 Not Cancer Driver No 1 intact, hippie 47 326 41 41 0
TIMM17B_ENST00000376582 TIMM17B O60830 Mitochondrial import inner membrane translocase subunit Tim17-B chrX Not Cancer Driver No 1 intact, hippie 23 27 4 4 0
TMEM171 TMEM171 Q8WVE6 Transmembrane protein 171 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 54 150 18 18 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TTC30B TTC30B Q8N4P2 Tetratricopeptide repeat protein 30B chr2 Not Cancer Driver No 2 intact, hippie 80 74 13 13 0