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MKNK1 ,MKNK1 ,Q9BUB5
  • Uniprot Accession= Q9BUB5
  • Ensembl Transcript= ENST00000371946.8
  • Uniprot Name= MKNK1
  • Name= MAP kinase-interacting serine/threonine-protein kinase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 21
  • Number of Interaction partner in hippie: 68
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 38 7 2 2 0
AHNAK2 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 hippie, biogrid 1074 5470 1018 1018 0
AMOTL2_ENST00000422605 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 94 741 93 93 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 hippie 193 604 168 168 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 Not Cancer Driver No 1 hippie 387 3023 384 384 0
BPIFA1_ENST00000375413 BPIFA1 Q9NP55 BPI fold-containing family A member 1 chr20 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 0
CAMKK1_ENST00000348335 CAMKK1 Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 82 246 32 32 0
CCDC149_ENST00000504487 CCDC149 Q6ZUS6-4 Isoform 4 of Coiled-coil domain-containing protein 149 chr4 Not Cancer Driver No 1 hippie, biogrid 35 415 26 26 0
CPSF6_ENST00000435070 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 Not Cancer Driver No 1 hippie, biogrid 85 484 75 75 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CREM_ENST00000429130 CREM Q03060 cAMP-responsive element modulator chr10 Not Cancer Driver No 1 hippie 32 289 26 26 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 Not Cancer Driver No 1 hippie 24 96 6 6 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie 41 102 9 9 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 1 hippie 26 54 6 6 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 Not Cancer Driver No 2 hippie, biogrid 229 1079 153 153 2
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 Not Cancer Driver No 1 hippie 104 382 43 43 0
EIF4G3_ENST00000264211 EIF4G3 O43432 Eukaryotic translation initiation factor 4 gamma 3 chr1 Not Cancer Driver No 1 hippie 200 1018 127 127 0
FANCA FANCA O15360 Fanconi anemia group A protein chr16 Census, Compendium Yes 1 hippie 160 154 15 15 27
FRK FRK P42685 Tyrosine-protein kinase FRK chr6 Not Cancer Driver No 1 hippie, biogrid 87 18 2 2 0
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 109 528 74 74 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 Not Cancer Driver No 1 hippie 154 686 96 96 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 hippie 336 666 69 69 2
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 Not Cancer Driver No 1 hippie 20 17 6 6 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 Not Cancer Driver No 1 hippie 114 405 60 60 0
KIF1C KIF1C O43896 Kinesin-like protein KIF1C chr17 Not Cancer Driver No 1 hippie 131 695 94 94 1
LLGL2 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 Not Cancer Driver No 1 hippie 120 266 26 26 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 Not Cancer Driver No 1 hippie 23 64 2 2 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 5 hippie, biogrid 39 25 1 1 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 3 hippie, biogrid 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 2 hippie, biogrid 38 49 5 5 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 Not Cancer Driver No 1 hippie 52 304 52 52 0
MKNK1 MKNK1 Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 chr1 Not Cancer Driver No 1 hippie 54 149 24 24 0
MKNK2_ENST00000591601 MKNK2 Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 chr19 Not Cancer Driver No 1 hippie, biogrid 42 124 8 8 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MYH13 MYH13 Q9UKX3 Myosin-13 chr17 Not Cancer Driver No 1 hippie 452 1082 237 237 0
NUP210 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie, biogrid 262 156 19 19 0
NUP214 NUP214 P35658 Nuclear pore complex protein Nup214 chr9 Census, Compendium Yes 1 hippie, biogrid 217 1479 146 146 2
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 1 hippie 89 242 49 49 0
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 1 hippie 50 166 23 23 0
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 52 50 10 10 0
PHAX PHAX Q9H814 Phosphorylated adapter RNA export protein chr5 Not Cancer Driver No 1 hippie 32 331 29 29 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 Not Cancer Driver No 1 hippie 149 129 28 28 1
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 11 24 3 3 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 41 12 1 1 8
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 538 421 61 61 2
PUSL1 PUSL1 Q8N0Z8 tRNA pseudouridine synthase-like 1 chr1 Not Cancer Driver No 1 hippie, biogrid 15 76 1 1 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie 32 65 15 15 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie, biogrid 157 730 84 84 0
RCN3 RCN3 Q96D15 Reticulocalbin-3 chr19 Not Cancer Driver No 1 hippie 44 243 39 39 0
RNASEH2B RNASEH2B Q5TBB1 Ribonuclease H2 subunit B chr13 Not Cancer Driver No 1 hippie 34 84 9 9 14
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie 16 6 2 2 0
S100A4_ENST00000354332 S100A4 P26447 Protein S100-A4 chr1 Not Cancer Driver No 1 hippie 9 6 2 2 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 hippie 5 4 0 0 0
S100P S100P P25815 Protein S100-P chr4 Not Cancer Driver No 1 hippie 7 3 1 1 0
SEC16A SEC16A O15027 Protein transport protein Sec16A chr9 Not Cancer Driver No 1 hippie, biogrid 285 1923 235 235 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 Not Cancer Driver No 1 hippie 46 169 29 29 1
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 hippie, biogrid 48 229 28 28 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie, biogrid 2891 282 1466 1466 83
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 Not Cancer Driver No 1 hippie 13 14 0 0 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie, biogrid 340 1296 162 162 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0