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MIER1_ENST00000355356 ,MIER1 ,Q8N108
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 20
  • Number of Interaction partner in hippie: 45
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 Not Cancer Driver No 1 intact, hippie 31 297 21 21 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARID5B ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 Not Cancer Driver No 1 hippie, biogrid 162 769 95 95 0
C16orf87 C16orf87 Q6PH81 UPF0547 protein C16orf87 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 17 103 8 8 0
CDY2B_ENST00000382867 CDY2B Q9Y6F7 Testis-specific chromodomain protein Y 2 chrY Not Cancer Driver No 1 hippie 0 248 0 0 0
CDYL_ENST00000328908 CDYL Q9Y232 Chromodomain Y-like protein chr6 Not Cancer Driver No 3 hippie, biogrid 99 346 61 61 0
CENPU CENPU Q71F23 Centromere protein U chr4 Not Cancer Driver No 1 hippie 51 298 42 42 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CYBRD1 CYBRD1 Q53TN4 Plasma membrane ascorbate-dependent reductase CYBRD1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 34 59 10 10 0
DOK4_ENST00000340099 DOK4 Q8TEW6 Docking protein 4 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 42 45 3 3 0
DR1_ENST00000370267 DR1 Q01658 Protein Dr1 chr1 Not Cancer Driver No 1 hippie, biogrid 21 84 12 12 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 Not Cancer Driver No 1 hippie 142 585 71 71 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FAM170A_ENST00000515256 FAM170A A1A519 Protein FAM170A chr5 Not Cancer Driver No 2 intact, hippie, biogrid 78 245 58 58 0
FAN1 FAN1 Q9Y2M0 Fanconi-associated nuclease 1 chr15 Not Cancer Driver No 1 hippie 124 212 27 27 4
FOXF2 FOXF2 Q12947 Forkhead box protein F2 chr6 Not Cancer Driver No 1 hippie, biogrid 44 277 10 10 0
GON4L GON4L Q3T8J9 GON-4-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 257 1708 210 210 0
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 2 intact 20 68 10 10 0
H2BFS H2BC12L P57053 Histone H2B type F-S chr21 Not Cancer Driver No 1 intact 1 86 1 1 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 6 intact, hippie, biogrid 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 4 intact, hippie, biogrid 46 145 14 14 0
HMG20A HMG20A Q9NP66 High mobility group protein 20A chr15 Not Cancer Driver No 1 hippie, biogrid 58 308 44 44 0
LIG1 LIG1 P18858 DNA ligase 1 chr19 Not Cancer Driver No 1 hippie 137 397 62 62 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie, biogrid 26 12 1 1 0
MRPL39_ENST00000352957 MRPL39 Q9NYK5 39S ribosomal protein L39, mitochondrial chr21 Not Cancer Driver No 1 hippie, biogrid 41 38 6 6 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie 284 10 0 0 14
PHF14 PHF14 O94880 PHD finger protein 14 chr7 Not Cancer Driver No 1 hippie, biogrid 102 565 56 56 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 Not Cancer Driver No 1 intact, hippie 120 459 54 54 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 intact, hippie 56 230 20 20 0
PPM1G PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie, biogrid 51 359 39 39 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 1 hippie, biogrid 30 305 30 30 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie, biogrid 198 195 17 17 8
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 Compendium Yes 1 intact, hippie 81 378 59 59 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 2 intact, hippie 39 312 39 39 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 73 141 24 24 3
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 intact, hippie 51 202 15 15 27
TMEM171 TMEM171 Q8WVE6 Transmembrane protein 171 chr5 Not Cancer Driver No 1 intact, hippie 54 150 18 18 0
TUBB1 TUBB1 Q9H4B7 Tubulin beta-1 chain chr20 Not Cancer Driver No 1 hippie, biogrid 71 38 4 4 1
UQCRC1 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie 57 55 6 6 2
WIZ_ENST00000263381 WIZ O95785-2 Isoform 2 of Protein Wiz chr19 Not Cancer Driver No 1 hippie 148 651 135 135 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 137 648 73 73 0