Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADAM30 | ADAM30 | Q9UKF2 | Disintegrin and metalloproteinase domain-containing protein 30 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 133 | 73 | 12 | 12 | 0 |
ADGRG5_ENST00000349457 | ADGRG5 | Q8IZF4 | Adhesion G-protein coupled receptor G5 | chr16 | Not Cancer Driver | No | 1 | hippie | 70 | 30 | 5 | 5 | 0 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
AKAP1_ENST00000539273 | AKAP1 | Q92667 | A-kinase anchor protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 537 | 67 | 67 | 0 |
ALG13 | ALG13 | Q9NP73 | Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 | chrX | Not Cancer Driver | No | 1 | hippie | 163 | 520 | 83 | 83 | 2 |
AMOT | AMOT | Q4VCS5 | Angiomotin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 161 | 909 | 128 | 128 | 0 |
ANO4 | ANO4 | Q32M45 | Anoctamin-4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 320 | 133 | 35 | 35 | 0 |
ANO6_ENST00000320560 | ANO6 | Q4KMQ2 | Anoctamin-6 | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 134 | 80 | 11 | 11 | 0 |
APOB | APOB | P04114 | Apolipoprotein B-100 | chr2 | Not Cancer Driver | No | 1 | hippie | 1022 | 315 | 72 | 72 | 3 |
ASPH | ASPH | Q12797 | Aspartyl/asparaginyl beta-hydroxylase | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 373 | 53 | 53 | 1 |
ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 63 | 8 | 8 | 0 |
B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
BACE2 | BACE2 | Q9Y5Z0 | Beta-secretase 2 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 23 | 2 | 2 | 0 |
BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
BRK1 | BRK1 | Q8WUW1 | Protein BRICK1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 14 | 1 | 1 | 0 |
CACNA1A_ENST00000360228 | CACNA1A | O00555 | Voltage-dependent P/Q-type calcium channel subunit alpha-1A | chr19 | Not Cancer Driver | No | 1 | hippie | 436 | 1144 | 132 | 132 | 46 |
CALR3 | CALR3 | Q96L12 | Calreticulin-3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 101 | 16 | 16 | 0 |
CALU_ENST00000249364 | CALU | O43852 | Calumenin | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 130 | 12 | 12 | 0 |
CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 334 | 38 | 38 | 0 |
CEP135 | CEP135 | Q66GS9 | Centrosomal protein of 135 kDa | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 690 | 72 | 72 | 0 |
CEP55 | CEP55 | Q53EZ4 | Centrosomal protein of 55 kDa | chr10 | Not Cancer Driver | No | 1 | hippie | 59 | 264 | 26 | 26 | 0 |
CFC1 | CFC1 | P0CG37 | Cryptic protein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 68 | 23 | 23 | 1 |
CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 409 | 55 | 55 | 0 |
CLEC4E | CLEC4E | Q9ULY5 | C-type lectin domain family 4 member E | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 5 | 2 | 2 | 0 |
CLIC3 | CLIC3 | O95833 | Chloride intracellular channel protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 23 | 36 | 3 | 3 | 0 |
CLTA | CLTA | P09496 | Clathrin light chain A | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 192 | 12 | 12 | 0 |
COL7A1 | COL7A1 | Q02388 | Collagen alpha-1(VII) chain | chr3 | Not Cancer Driver | No | 1 | hippie | 462 | 2303 | 397 | 397 | 77 |
COLEC10 | COLEC10 | Q9Y6Z7 | Collectin-10 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 95 | 23 | 23 | 1 |
CRTAP | CRTAP | O75718 | Cartilage-associated protein | chr3 | Not Cancer Driver | No | 3 | hippie, biogrid | 29 | 0 | 0 | 0 | 3 |
CTAGE1 | CTAGE1 | Q96RT6 | cTAGE family member 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 169 | 493 | 106 | 106 | 0 |
CTAGE15 | CTAGE15 | A4D2H0 | cTAGE family member 15 | chr7 | Not Cancer Driver | No | 1 | hippie | 34 | 502 | 14 | 14 | 0 |
CTAGE6 | CTAGE6 | Q86UF2 | cTAGE family member 6 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 88 | 501 | 48 | 48 | 0 |
CTSB | CTSB | P07858 | Cathepsin B | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 7 | 2 | 2 | 0 |
CTSL | CTSL | P07711 | Procathepsin L | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 34 | 4 | 4 | 0 |
CTSS | CTSS | P25774 | Cathepsin S | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 0 | 0 | 0 | 0 |
CYP2C9 | CYP2C9 | P11712 | Cytochrome P450 2C9 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 122 | 36 | 14 | 14 | 0 |
DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 11 | 1 | 1 | 0 |
DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 54 | 8 | 8 | 1 |
DNAJB11_ENST00000265028 | DNAJB11 | Q9UBS4 | DnaJ homolog subfamily B member 11 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 141 | 21 | 21 | 2 |
DNAJB12_ENST00000444643 | DNAJB12 | Q9NXW2 | DnaJ homolog subfamily B member 12 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 227 | 20 | 20 | 0 |
DNAJB9 | DNAJB9 | Q9UBS3 | DnaJ homolog subfamily B member 9 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 30 | 107 | 15 | 15 | 0 |
DNAJC1 | DNAJC1 | Q96KC8 | DnaJ homolog subfamily C member 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 315 | 44 | 44 | 0 |
DNAJC10 | DNAJC10 | Q8IXB1 | DnaJ homolog subfamily C member 10 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 110 | 36 | 3 | 3 | 0 |
DNAJC16 | DNAJC16 | Q9Y2G8 | DnaJ homolog subfamily C member 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 63 | 2 | 2 | 0 |
DNAJC25 | DNAJC25 | Q9H1X3 | DnaJ homolog subfamily C member 25 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 39 | 3 | 3 | 0 |
DNAJC3 | DNAJC3 | Q13217 | DnaJ homolog subfamily C member 3 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 131 | 17 | 17 | 0 |
DNAJC30 | DNAJC30 | Q96LL9 | DnaJ homolog subfamily C member 30, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 83 | 7 | 7 | 3 |
DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
ECEL1 | ECEL1 | O95672 | Endothelin-converting enzyme-like 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 103 | 22 | 2 | 2 | 4 |
EDN3_ENST00000371028 | EDN3 | P14138 | Endothelin-3 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 140 | 44 | 44 | 3 |
EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
ERGIC1 | ERGIC1 | Q969X5 | Endoplasmic reticulum-Golgi intermediate compartment protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 26 | 2 | 2 | 0 |
ERGIC2 | ERGIC2 | Q96RQ1 | Endoplasmic reticulum-Golgi intermediate compartment protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 25 | 2 | 2 | 0 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
EWSR1_ENST00000397938 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | hippie | 94 | 646 | 93 | 93 | 0 |
EYA2 | EYA2 | O00167 | Eyes absent homolog 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 107 | 204 | 50 | 50 | 0 |
FAM120C | FAM120C | Q9NX05 | Constitutive coactivator of PPAR-gamma-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 162 | 508 | 77 | 77 | 0 |
FAM167A | FAM167A | Q96KS9 | Protein FAM167A | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 116 | 17 | 17 | 0 |
FAM19A4 | TAFA4 | Q96LR4 | Chemokine-like protein TAFA-4 | chr3 | Not Cancer Driver | No | 1 | hippie | 38 | 4 | 1 | 1 | 0 |
FBXO2 | FBXO2 | Q9UK22 | F-box only protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 75 | 1 | 1 | 0 |
FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 160 | 25 | 25 | 0 |
FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | Not Cancer Driver | No | 1 | hippie | 124 | 327 | 70 | 70 | 3 |
FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 88 | 312 | 53 | 53 | 0 |
FXR2 | FXR2 | P51116 | Fragile X mental retardation syndrome-related protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 68 | 388 | 42 | 42 | 0 |
GABRE | GABRE | P78334 | Gamma-aminobutyric acid receptor subunit epsilon | chrX | Not Cancer Driver | No | 3 | hippie, biogrid | 133 | 73 | 19 | 19 | 0 |
GGH | GGH | Q92820 | Gamma-glutamyl hydrolase | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 5 | 0 | 0 | 0 |
GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 110 | 26 | 26 | 50 |
GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
GPRC5B_ENST00000569479 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 75 | 19 | 19 | 0 |
GXYLT1 | GXYLT1 | Q4G148 | Glucoside xylosyltransferase 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 7 | 0 | 0 | 0 |
HAO2_ENST00000325945 | HAO2 | Q9NYQ3 | 2-Hydroxyacid oxidase 2 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 102 | 12 | 5 | 5 | 0 |
HLA-DRA | HLA-DRA | P01903 | HLA class II histocompatibility antigen, DR alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 12 | 1 | 1 | 0 |
HLA-DRB1 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 12 | 1 | 1 | 0 |
HNRNPA1L2 | HNRNPA1L2 | Q32P51 | Heterogeneous nuclear ribonucleoprotein A1-like 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 29 | 235 | 23 | 23 | 0 |
HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
HOMER3_ENST00000542541 | HOMER3 | Q9NSC5 | Homer protein homolog 3 | chr19 | Not Cancer Driver | No | 1 | hippie | 31 | 251 | 15 | 15 | 0 |
HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
HSD17B14 | HSD17B14 | Q9BPX1 | 17-beta-hydroxysteroid dehydrogenase 14 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 42 | 10 | 10 | 0 |
HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
HSPA13 | HSPA13 | P48723 | Heat shock 70 kDa protein 13 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 48 | 7 | 7 | 0 |
HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 282 | 35 | 35 | 0 |
ITGAX_ENST00000268296 | ITGAX | P20702 | Integrin alpha-X | chr16 | Not Cancer Driver | No | 1 | hippie | 245 | 82 | 15 | 15 | 0 |
KRT8_ENST00000546897 | KRT8 | P05787 | Keratin, type II cytoskeletal 8 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 221 | 37 | 37 | 3 |
LATS1 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | Census, Compendium | Yes | 1 | hippie, biogrid | 161 | 788 | 100 | 100 | 0 |
LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | Census, Compendium | Yes | 1 | hippie, biogrid | 178 | 687 | 116 | 116 | 0 |
LENG8 | LENG8 | Q96PV6 | Leukocyte receptor cluster member 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 137 | 515 | 97 | 97 | 0 |
LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 222 | 25 | 25 | 1 |
LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
LNPK_ENST00000272748 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 62 | 257 | 43 | 43 | 0 |
LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 122 | 15 | 15 | 0 |
METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
MIA2_ENST00000640607 | MIA2 | Q96PC5 | Melanoma inhibitory activity protein 2 | chr14 | Not Cancer Driver | No | 2 | hippie | 214 | 961 | 155 | 155 | 0 |
MIA3 | MIA3 | Q5JRA6 | Transport and Golgi organization protein 1 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 1490 | 178 | 178 | 0 |
MINOS1 | MICOS10 | Q5TGZ0 | MICOS complex subunit MIC10 | chr1 | Not Cancer Driver | No | 1 | hippie | 5 | 0 | 0 | 0 | 0 |
MTMR14 | MTMR14 | Q8NCE2 | Myotubularin-related protein 14 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 150 | 8 | 8 | 2 |
MTMR7 | MTMR7 | Q9Y216 | Myotubularin-related protein 7 | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 98 | 160 | 26 | 26 | 0 |
MTNR1B | MTNR1B | P49286 | Melatonin receptor type 1B | chr11 | Not Cancer Driver | No | 1 | hippie | 104 | 8 | 1 | 1 | 0 |
NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | Not Cancer Driver | No | 1 | hippie | 89 | 88 | 19 | 19 | 0 |
NCR3 | NCR3 | O14931 | Natural cytotoxicity triggering receptor 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 31 | 2 | 2 | 0 |
NDC80 | NDC80 | O14777 | Kinetochore protein NDC80 homolog | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 313 | 45 | 45 | 0 |
NIN | NIN | Q8N4C6 | Ninein | chr14 | Census, Compendium | Yes | 1 | hippie | 239 | 1392 | 164 | 164 | 2 |
NOP56 | NOP56 | O00567 | Nucleolar protein 56 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 191 | 34 | 34 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 221 | 19 | 19 | 1 |
NXPH3 | NXPH3 | O95157 | Neurexophilin-3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 82 | 14 | 14 | 0 |
OCLN | OCLN | Q16625 | Occludin | chr5 | Not Cancer Driver | No | 1 | biogrid | 54 | 244 | 21 | 21 | 1 |
P3H1_ENST00000296388 | P3H1 | Q32P28 | Prolyl 3-hydroxylase 1 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 91 | 177 | 18 | 18 | 0 |
PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
PATL1 | PATL1 | Q86TB9 | Protein PAT1 homolog 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 79 | 499 | 49 | 49 | 0 |
PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
PPFIBP2 | PPFIBP2 | Q8ND30 | Liprin-beta-2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 494 | 58 | 58 | 0 |
PRDM14 | PRDM14 | Q9GZV8 | PR domain zinc finger protein 14 | chr8 | Not Cancer Driver | No | 1 | hippie | 122 | 179 | 37 | 37 | 0 |
PRG2 | PRG2 | P13727 | Bone marrow proteoglycan | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 65 | 15 | 15 | 0 |
PRRC2B | PRRC2B | Q5JSZ5 | Protein PRRC2B | chr9 | Not Cancer Driver | No | 1 | hippie | 279 | 2199 | 278 | 278 | 0 |
PRTN3 | PRTN3 | P24158 | Myeloblastin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 46 | 1 | 1 | 0 |
PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 140 | 25 | 25 | 0 |
PTPRN | PTPRN | Q16849 | Receptor-type tyrosine-protein phosphatase-like N | chr2 | Not Cancer Driver | No | 1 | hippie | 142 | 498 | 73 | 73 | 0 |
PXMP2 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
PXN_ENST00000228307 | PXN | P49023 | Paxillin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 341 | 24 | 24 | 0 |
QPRT | QPRT | Q15274 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 7 | 1 | 1 | 0 |
RAB4A | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 32 | 11 | 11 | 0 |
RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 65 | 15 | 15 | 0 |
RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 21 | 1 | 1 | 0 |
REEP5 | REEP5 | Q00765 | Receptor expression-enhancing protein 5 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 0 | 0 | 0 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 79 | 5 | 5 | 0 |
RIPK4_ENST00000352483 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | hippie | 119 | 232 | 34 | 34 | 3 |
RMDN3 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 196 | 17 | 17 | 0 |
RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
SAV1 | SAV1 | Q9H4B6 | Protein salvador homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 243 | 17 | 17 | 0 |
SCFD1 | SCFD1 | Q8WVM8 | Sec1 family domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 66 | 117 | 12 | 12 | 0 |
SDF2L1 | SDF2L1 | Q9HCN8 | Stromal cell-derived factor 2-like protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 130 | 9 | 9 | 0 |
SEC11A_ENST00000268220 | SEC11A | P67812 | Signal peptidase complex catalytic subunit SEC11A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
SEC16A | SEC16A | O15027 | Protein transport protein Sec16A | chr9 | Not Cancer Driver | No | 1 | hippie | 285 | 1923 | 235 | 235 | 0 |
SEC23A | SEC23A | Q15436 | Protein transport protein Sec23A | chr14 | Not Cancer Driver | No | 1 | hippie | 100 | 73 | 8 | 8 | 1 |
SEC24C | SEC24C | P53992 | Protein transport protein Sec24C | chr10 | Not Cancer Driver | No | 1 | hippie | 121 | 402 | 38 | 38 | 0 |
SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
SERPINA10 | SERPINA10 | Q9UK55 | Protein Z-dependent protease inhibitor | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 108 | 74 | 18 | 18 | 0 |
SERPINA12 | SERPINA12 | Q8IW75 | Serpin A12 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 90 | 22 | 3 | 3 | 0 |
SERPINA3_ENST00000393080 | SERPINA3 | P01011 | Alpha-1-antichymotrypsin | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 18 | 10 | 10 | 0 |
SERPINA5_ENST00000554276 | SERPINA5 | P05154 | Plasma serine protease inhibitor | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 103 | 24 | 17 | 17 | 0 |
SERPINA7 | SERPINA7 | P05543 | Thyroxine-binding globulin | chrX | Not Cancer Driver | No | 3 | hippie, biogrid | 108 | 11 | 2 | 2 | 0 |
SIDT2_ENST00000620360 | SIDT2 | Q8NBJ9 | SID1 transmembrane family member 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 113 | 23 | 6 | 6 | 0 |
SIGLEC12 | SIGLEC12 | Q96PQ1 | Sialic acid-binding Ig-like lectin 12 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 150 | 213 | 56 | 56 | 0 |
SIRPD | SIRPD | Q9H106 | Signal-regulatory protein delta | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 66 | 17 | 17 | 0 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 164 | 12 | 12 | 0 |
SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 96 | 2 | 2 | 4 |
SLC39A5 | SLC39A5 | Q6ZMH5 | Zinc transporter ZIP5 | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 67 | 139 | 18 | 18 | 1 |
SLC39A7 | SLC39A7 | Q92504 | Zinc transporter SLC39A7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 192 | 17 | 17 | 0 |
SMAP2 | SMAP2 | Q8WU79 | Stromal membrane-associated protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 50 | 214 | 30 | 30 | 0 |
SORT1 | SORT1 | Q99523 | Sortilin | chr1 | Not Cancer Driver | No | 1 | hippie | 69 | 110 | 2 | 2 | 0 |
SPCS2 | SPCS2 | Q15005 | Signal peptidase complex subunit 2 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 17 | 0 | 0 | 0 | 0 |
SPCS3 | SPCS3 | P61009 | Signal peptidase complex subunit 3 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 0 | 0 | 0 | 0 |
SRPRB | SRPRB | Q9Y5M8 | Signal recognition particle receptor subunit beta | chr3 | Not Cancer Driver | No | 3 | hippie, biogrid | 30 | 23 | 3 | 3 | 0 |
SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 64 | 5 | 5 | 0 |
STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 387 | 45 | 45 | 13 |
STX1A | STX1A | Q16623 | Syntaxin-1A | chr7 | Not Cancer Driver | No | 1 | hippie | 35 | 136 | 11 | 11 | 0 |
STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
STX6 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 78 | 11 | 11 | 0 |
STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 164 | 14 | 14 | 0 |
SYCE1_ENST00000343131 | SYCE1 | Q8N0S2 | Synaptonemal complex central element protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 251 | 50 | 50 | 0 |
SYNE3 | SYNE3 | Q6ZMZ3 | Nesprin-3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 236 | 42 | 42 | 0 |
TACC3 | TACC3 | Q9Y6A5 | Transforming acidic coiled-coil-containing protein 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 98 | 707 | 81 | 81 | 0 |
TAX1BP1 | TAX1BP1 | Q86VP1 | Tax1-binding protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 78 | 429 | 50 | 50 | 0 |
TCTN1_ENST00000551590 | TCTN1 | Q2MV58 | Tectonic-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 63 | 47 | 6 | 6 | 0 |
TDRD3_ENST00000196169 | TDRD3 | Q9H7E2 | Tudor domain-containing protein 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 97 | 518 | 77 | 77 | 0 |
TMEM106A | TMEM106A | Q96A25 | Transmembrane protein 106A | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 9 | 1 | 1 | 0 |
TMEM106B | TMEM106B | Q9NUM4 | Transmembrane protein 106B | chr7 | Not Cancer Driver | No | 1 | hippie | 31 | 56 | 4 | 4 | 1 |
TMEM87A | TMEM87A | Q8NBN3 | Transmembrane protein 87A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 71 | 10 | 10 | 0 |
TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 412 | 52 | 52 | 0 |
TMPRSS11B | TMPRSS11B | Q86T26 | Transmembrane protease serine 11B | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 5 | 0 | 0 | 0 |
TMPRSS2_ENST00000458356 | TMPRSS2 | O15393 | Transmembrane protease serine 2 | chr21 | Census | Yes | 1 | hippie, biogrid | 66 | 25 | 5 | 5 | 0 |
TOMM20 | TOMM20 | Q15388 | Mitochondrial import receptor subunit TOM20 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 8 | 25 | 1 | 1 | 0 |
TPR | TPR | P12270 | Nucleoprotein TPR | chr1 | Census | Yes | 1 | hippie | 311 | 1990 | 266 | 266 | 0 |
TRIM27 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | Census | Yes | 1 | hippie | 59 | 87 | 11 | 11 | 0 |
TTYH1_ENST00000376530 | TTYH1 | Q9H313 | Protein tweety homolog 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 21 | 3 | 3 | 0 |
UQCC1 | UQCC1 | Q9NVA1 | Ubiquinol-cytochrome-c reductase complex assembly factor 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 59 | 10 | 10 | 0 |
VAPA_ENST00000400000 | VAPA | Q9P0L0 | Vesicle-associated membrane protein-associated protein A | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 184 | 14 | 14 | 0 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
VNN2 | VNN2 | O95498 | Pantetheine hydrolase VNN2 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 96 | 15 | 3 | 3 | 0 |
VPS18 | VPS18 | Q9P253 | Vacuolar protein sorting-associated protein 18 homolog | chr15 | Not Cancer Driver | No | 1 | hippie | 96 | 86 | 7 | 7 | 0 |
VPS33B | VPS33B | Q9H267 | Vacuolar protein sorting-associated protein 33B | chr15 | Not Cancer Driver | No | 1 | hippie | 54 | 17 | 0 | 0 | 2 |
WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 108 | 9 | 9 | 3 |
XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 213 | 577 | 65 | 65 | 0 |
ZNF444 | ZNF444 | Q8N0Y2 | Zinc finger protein 444 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 17 | 221 | 13 | 13 | 0 |
ZRANB1 | ZRANB1 | Q9UGI0 | Ubiquitin thioesterase ZRANB1 | chr10 | Not Cancer Driver | No | 1 | hippie | 87 | 158 | 25 | 25 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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