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MEFV ,MEFV ,O15553
  • Uniprot Accession= O15553
  • Ensembl Transcript= ENST00000219596.5
  • Uniprot Name= MEFV
  • Name= Pyrin
  • Chromosome= chr16
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 3
  • Number of Interaction partner in biogrid: 1
  • Number of Interaction partner in hippie: 20
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 45 190 19 19 0
CASP1 CASP1 P29466 Caspase-1 chr11 Not Cancer Driver No 1 hippie 79 87 18 18 0
COG5_ENST00000347053 COG5 Q9UP83 Conserved oligomeric Golgi complex subunit 5 chr7 Not Cancer Driver No 1 hippie 101 118 23 23 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie 15 133 6 6 0
LGALS8_ENST00000366584 LGALS8 O00214 Galectin-8 chr1 Not Cancer Driver No 1 hippie 43 31 6 6 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP1LC3C MAP1LC3C Q9BXW4 Microtubule-associated proteins 1A/1B light chain 3C chr1 Not Cancer Driver No 1 hippie 32 31 5 5 0
MEFV MEFV O15553 Pyrin chr16 Not Cancer Driver No 3 intact, hippie 196 397 119 119 47
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 Not Cancer Driver No 1 hippie 339 64 33 33 37
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 1 hippie 118 246 34 34 0
PSTPIP1 PSTPIP1 O43586 Proline-serine-threonine phosphatase-interacting protein 1 chr15 Not Cancer Driver No 1 hippie 46 225 26 26 3
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 Not Cancer Driver No 1 hippie 16 39 4 4 0
SIVA1 SIVA1 O15304 Apoptosis regulatory protein Siva chr14 Not Cancer Driver No 1 hippie 20 20 6 6 0
SPICE1 SPICE1 Q8N0Z3 Spindle and centriole-associated protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 112 729 92 92 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 Not Cancer Driver No 1 hippie 142 588 77 77 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 intact, hippie 29 41 6 6 0