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MEF2D ,MEF2D ,Q14814
  • Uniprot Accession= Q14814
  • Ensembl Transcript= ENST00000348159.8
  • Uniprot Name= MEF2D
  • Name= Myocyte-specific enhancer factor 2D
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 23
  • Number of Interaction partner in biogrid: 11
  • Number of Interaction partner in hippie: 74
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 Not Cancer Driver No 1 hippie 33 182 24 24 0
ASF1A ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 1 hippie, biogrid 18 69 2 2 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 Not Cancer Driver No 1 hippie 95 293 39 39 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BORCS8-MEF2B_ENST00000514819 BORCS8-MEF2B H3BNR1 BORCS8-MEF2B readthrough chr19 Not Cancer Driver No 1 hippie 40 325 32 32 0
CABIN1 CABIN1 Q9Y6J0 Calcineurin-binding protein cabin-1 chr22 Not Cancer Driver No 1 hippie 225 1008 95 95 0
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 Not Cancer Driver No 1 hippie 62 102 10 10 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 38 73 10 10 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 Census Yes 1 intact, hippie 40 24 3 3 1
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 Not Cancer Driver No 1 hippie 83 10 1 1 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 intact, hippie 95 296 54 54 0
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie, biogrid 51 524 51 51 20
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HIRA HIRA P54198 Protein HIRA chr22 Not Cancer Driver No 1 hippie 138 288 37 37 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie, biogrid 149 251 52 52 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 Census, Compendium Yes 1 hippie 99 155 45 45 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 1 hippie 107 266 27 27 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 13 204 8 8 0
KLF3 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 1 intact, hippie 53 243 38 38 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 Compendium Yes 1 hippie 77 366 40 40 0
KLF8 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 intact, hippie 71 270 53 53 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 1 hippie 773 4386 552 552 13
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 Not Cancer Driver No 1 intact, hippie 60 203 28 28 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 Not Cancer Driver No 1 intact, hippie 38 232 14 14 2
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 Not Cancer Driver No 1 intact, hippie 75 219 45 45 4
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 4 intact, hippie, biogrid 39 25 1 1 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 Not Cancer Driver No 1 hippie 92 490 50 50 0
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 Not Cancer Driver No 3 intact, hippie, biogrid 62 454 56 56 0
MEF2B MEF2B Q02080-2 Isoform 2 of Myocyte-specific enhancer factor 2B chr19 Compendium Yes 1 intact, hippie, biogrid 37 302 26 26 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 Not Cancer Driver No 1 hippie 92 408 81 81 0
MEF2D MEF2D Q14814 Myocyte-specific enhancer factor 2D chr1 Not Cancer Driver No 1 hippie 72 455 67 67 0
MEN1 MEN1 O00255 Menin chr11 Census, Compendium Yes 1 hippie 73 228 15 15 90
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie 194 722 162 162 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PAX7_ENST00000420770 PAX7 P23759 Paired box protein Pax-7 chr1 Census Yes 1 intact, hippie 97 401 77 77 1
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 Census Yes 1 intact, hippie 84 291 55 55 4
PAX9 PAX9 P55771 Paired box protein Pax-9 chr14 Not Cancer Driver No 1 intact, hippie 52 198 32 32 1
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 hippie 83 72 6 6 0
RAVER1_ENST00000615032 RAVER1 Q8IY67 Ribonucleoprotein PTB-binding 1 chr19 Not Cancer Driver No 1 intact 61 330 22 22 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 Not Cancer Driver No 1 hippie 57 218 19 19 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 Not Cancer Driver No 1 hippie 53 288 30 30 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie 52 52 6 6 0
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie 134 664 82 82 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 intact, hippie 130 744 118 118 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TAX1BP3 TAX1BP3 O14907 Tax1-binding protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 16 51 8 8 0
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 Not Cancer Driver No 1 hippie 52 157 24 24 1
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 310 16 16 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 Not Cancer Driver No 1 hippie 55 280 26 26 0
TLX1 TLX1 P31314 T-cell leukemia homeobox protein 1 chr10 Census Yes 1 intact, hippie 28 223 17 17 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 66 232 29 29 4
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 intact, hippie 29 41 6 6 0