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MED18_ENST00000398997 ,MED18 ,Q9BUE0
  • Uniprot Accession= Q9BUE0
  • Ensembl Transcript= ENST00000398997.2
  • Uniprot Name= MED18
  • Name= Mediator of RNA polymerase II transcription subunit 18
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 40
  • Number of Interaction partner in biogrid: 50
  • Number of Interaction partner in hippie: 66
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAD11 ACAD11 Q709F0 Acyl-CoA dehydrogenase family member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 108 33 4 4 0
AFMID_ENST00000409257 AFMID Q63HM1 Kynurenine formamidase chr17 Not Cancer Driver No 1 intact, hippie 46 12 1 1 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ATAD3B ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 hippie, biogrid 84 243 19 19 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 Not Cancer Driver No 2 hippie, biogrid 20 49 6 6 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 Not Cancer Driver No 1 intact, hippie 86 273 28 28 6
CCNC CCNC P24863 Cyclin-C chr6 Census Yes 5 intact, hippie, biogrid 32 33 3 3 0
CCNH CCNH P51946 Cyclin-H chr5 Not Cancer Driver No 1 hippie 40 28 4 4 0
CDK19 CDK19 Q9BWU1 Cyclin-dependent kinase 19 chr6 Not Cancer Driver No 6 intact, hippie, biogrid 63 191 28 28 8
CDK8 CDK8 P49336 Cyclin-dependent kinase 8 chr13 Not Cancer Driver No 6 intact, hippie, biogrid 76 152 18 18 7
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 1 hippie 120 449 53 53 6
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX Not Cancer Driver No 2 intact, hippie, biogrid 86 28 3 3 58
GPN3_ENST00000228827 GPN3 Q9UHW5 GPN-loop GTPase 3 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 28 19 0 0 0
HOMEZ HOMEZ Q8IX15 Homeobox and leucine zipper protein Homez chr14 Not Cancer Driver No 2 intact, hippie 83 401 70 70 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 Not Cancer Driver No 1 intact, hippie, biogrid 37 86 12 12 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 6 hippie, biogrid 162 1104 117 117 0
MED10 MED10 Q9BTT4 Mediator of RNA polymerase II transcription subunit 10 chr5 Not Cancer Driver No 8 intact, hippie, biogrid 14 13 3 3 0
MED11 MED11 Q9P086 Mediator of RNA polymerase II transcription subunit 11 chr17 Not Cancer Driver No 5 hippie, biogrid 12 24 4 4 0
MED12 MED12 Q93074 Mediator of RNA polymerase II transcription subunit 12 chrX Census, Compendium Yes 5 intact, hippie, biogrid 409 974 175 175 5
MED12L MED12L Q86YW9 Mediator of RNA polymerase II transcription subunit 12-like protein chr3 Not Cancer Driver No 3 intact, hippie, biogrid 372 822 153 153 0
MED13 MED13 Q9UHV7 Mediator of RNA polymerase II transcription subunit 13 chr17 Not Cancer Driver No 5 hippie, biogrid 288 905 127 127 3
MED13L MED13L Q71F56 Mediator of RNA polymerase II transcription subunit 13-like chr12 Not Cancer Driver No 3 hippie, biogrid 274 1074 142 142 0
MED14 MED14 O60244 Mediator of RNA polymerase II transcription subunit 14 chrX Not Cancer Driver No 6 hippie, biogrid 182 318 45 45 0
MED15 MED15 Q96RN5 Mediator of RNA polymerase II transcription subunit 15 chr22 Not Cancer Driver No 5 intact, hippie, biogrid 95 558 72 72 0
MED16 MED16 Q9Y2X0 Mediator of RNA polymerase II transcription subunit 16 chr19 Not Cancer Driver No 6 intact, hippie, biogrid 100 87 7 7 0
MED17 MED17 Q9NVC6 Mediator of RNA polymerase II transcription subunit 17 chr11 Not Cancer Driver No 6 intact, hippie, biogrid 75 182 17 17 1
MED18_ENST00000398997 MED18 Q9BUE0 Mediator of RNA polymerase II transcription subunit 18 chr1 Not Cancer Driver No 1 intact, hippie 35 10 2 2 0
MED20 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 7 intact, hippie, biogrid 22 0 0 0 0
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 5 hippie, biogrid 12 46 3 3 0
MED22_ENST00000343730 MED22 Q15528 Mediator of RNA polymerase II transcription subunit 22 chr9 Not Cancer Driver No 4 intact, hippie, biogrid 26 98 12 12 0
MED23 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 5 intact, hippie, biogrid 158 28 2 2 1
MED24_ENST00000394128 MED24 O75448 Mediator of RNA polymerase II transcription subunit 24 chr17 Not Cancer Driver No 6 hippie, biogrid 101 76 0 0 0
MED25 MED25 Q71SY5 Mediator of RNA polymerase II transcription subunit 25 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 103 432 54 54 2
MED26 MED26 O95402 Mediator of RNA polymerase II transcription subunit 26 chr19 Not Cancer Driver No 4 hippie, biogrid 71 541 61 61 0
MED27 MED27 Q6P2C8 Mediator of RNA polymerase II transcription subunit 27 chr9 Not Cancer Driver No 5 intact, hippie, biogrid 34 61 5 5 0
MED28 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 4 hippie, biogrid 24 101 18 18 0
MED29_ENST00000599213 MED29 Q9NX70 Mediator of RNA polymerase II transcription subunit 29 chr19 Not Cancer Driver No 8 intact, hippie, biogrid 21 119 10 10 0
MED30 MED30 Q96HR3 Mediator of RNA polymerase II transcription subunit 30 chr8 Not Cancer Driver No 4 hippie, biogrid 20 93 8 8 0
MED31 MED31 Q9Y3C7 Mediator of RNA polymerase II transcription subunit 31 chr17 Not Cancer Driver No 4 hippie, biogrid 16 15 1 1 0
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 6 hippie, biogrid 29 161 17 17 0
MED6_ENST00000256379 MED6 O75586 Mediator of RNA polymerase II transcription subunit 6 chr14 Not Cancer Driver No 5 hippie, biogrid 21 79 4 4 0
MED7 MED7 O43513 Mediator of RNA polymerase II transcription subunit 7 chr5 Not Cancer Driver No 4 intact, hippie, biogrid 32 132 19 19 0
MED8_ENST00000372457 MED8 Q96G25 Mediator of RNA polymerase II transcription subunit 8 chr1 Not Cancer Driver No 6 intact, hippie, biogrid 29 191 24 24 0
MED9 MED9 Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 chr17 Not Cancer Driver No 5 intact, hippie, biogrid 16 127 15 15 0
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 130 501 66 66 0
MTMR4 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 147 474 59 59 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 75 38 4 4 0
ODF3 ODF3 Q96PU9 Outer dense fiber protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 22 174 14 14 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 2 intact, hippie, biogrid 56 230 20 20 0
POLR2B_ENST00000314595 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 166 173 25 25 0
POLR2C POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 34 108 11 11 0
POLR2E POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 31 36 3 3 0
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 15 15 1 1 0
POLR2H_ENST00000456318 POLR2H P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 16 14 1 1 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 21 22 5 5 0
POLR2J POLR2J P52435 DNA-directed RNA polymerase II subunit RPB11-a chr7 Not Cancer Driver No 1 intact, hippie, biogrid 12 0 0 0 0
RAVER1_ENST00000615032 RAVER1 Q8IY67 Ribonucleoprotein PTB-binding 1 chr19 Not Cancer Driver No 1 intact 61 330 22 22 0
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 56 293 25 25 0
TEPSIN TEPSIN Q96N21 AP-4 complex accessory subunit Tepsin chr17 Not Cancer Driver No 1 intact, hippie 54 321 37 37 0
THOC7 THOC7 Q6I9Y2 THO complex subunit 7 homolog chr3 Not Cancer Driver No 1 hippie 26 63 5 5 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 227 1632 190 190 0
TRIM39 TRIM39 Q9HCM9 E3 ubiquitin-protein ligase TRIM39 chr6 Not Cancer Driver No 2 intact, hippie 74 62 8 8 0
USP49 USP49 Q70CQ1 Ubiquitin carboxyl-terminal hydrolase 49 chr6 Not Cancer Driver No 1 hippie 81 190 19 19 0