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MECP2_ENST00000303391 ,MECP2 ,P51608
  • Uniprot Accession= P51608
  • Ensembl Transcript= ENST00000303391.10
  • Uniprot Name= MECP2
  • Name= Methyl-CpG-binding protein 2
  • Chromosome= chrX
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 121
  • Number of Interaction partner in biogrid: 148
  • Number of Interaction partner in hippie: 257
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD17C ABHD17C Q6PCB6 Alpha/beta hydrolase domain-containing protein 17C chr15 Not Cancer Driver No 1 intact, hippie 21 53 0 0 0
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 78 22 22 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 1 hippie 85 95 12 12 0
AP4S1_ENST00000616371 AP4S1 Q9Y587 AP-4 complex subunit sigma-1 chr14 Not Cancer Driver No 1 intact, hippie 11 0 0 0 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARHGAP22_ENST00000249601 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 138 449 90 90 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 Not Cancer Driver No 1 hippie, biogrid 68 297 13 13 0
ARHGEF19 ARHGEF19 Q8IW93 Rho guanine nucleotide exchange factor 19 chr1 Not Cancer Driver No 1 hippie, biogrid 82 365 36 36 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 Not Cancer Driver No 1 hippie, biogrid 170 1141 127 127 0
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 intact, hippie 71 0 0 0 0
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 Not Cancer Driver No 1 hippie 8 85 7 7 0
ATRX ATRX P46100 Transcriptional regulator ATRX chrX Census, Compendium Yes 1 intact, hippie 487 1672 301 301 33
ATXN2L_ENST00000336783 ATXN2L Q8WWM7 Ataxin-2-like protein chr16 Not Cancer Driver No 1 hippie, biogrid 135 1000 131 131 0
BAZ1A_ENST00000382422 BAZ1A Q9NRL2 Bromodomain adjacent to zinc finger domain protein 1A chr14 Census Yes 2 intact, hippie, biogrid 156 752 65 65 0
BBX BBX Q8WY36 HMG box transcription factor BBX chr3 Not Cancer Driver No 2 intact, hippie, biogrid 147 842 125 125 0
BLM BLM P54132 Bloom syndrome protein chr15 Census Yes 2 hippie, biogrid 153 667 70 70 8
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRD3 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie 87 566 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRIX1 BRIX1 Q8TDN6 Ribosome biogenesis protein BRX1 homolog chr5 Not Cancer Driver No 2 intact, hippie, biogrid 34 149 10 10 0
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 Not Cancer Driver No 1 hippie 7 14 1 1 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
C18orf21 C18orf21 Q32NC0 UPF0711 protein C18orf21 chr18 Not Cancer Driver No 2 intact, hippie, biogrid 21 112 12 12 0
CAT CAT P04040 Catalase chr11 Not Cancer Driver No 1 hippie, biogrid 70 176 18 18 0
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 Not Cancer Driver No 1 hippie 31 154 25 25 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 2 hippie, biogrid 23 119 18 18 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 hippie 21 116 12 12 0
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 85 495 61 61 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 39 23 2 2 1
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX Not Cancer Driver No 1 hippie 165 685 120 120 18
CEBPZ CEBPZ Q03701 CCAAT/enhancer-binding protein zeta chr2 Not Cancer Driver No 2 hippie, biogrid 95 488 44 44 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 1 hippie, biogrid 15 50 4 4 0
CENPV CENPV Q7Z7K6 Centromere protein V chr17 Not Cancer Driver No 2 intact, hippie, biogrid 16 154 2 2 0
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 Not Cancer Driver No 2 intact, hippie, biogrid 18 110 6 6 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 55 55 0
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 Not Cancer Driver No 1 intact, hippie 55 67 10 10 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie, biogrid 55 398 52 52 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 intact, hippie 25 277 23 23 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 hippie, biogrid 59 132 16 16 2
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 Not Cancer Driver No 1 hippie, biogrid 78 465 56 56 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 Not Cancer Driver No 1 hippie 46 96 0 0 0
DCAF13_ENST00000612750 DCAF13 Q9NV06 DDB1- and CUL4-associated factor 13 chr8 Not Cancer Driver No 1 hippie, biogrid 85 101 18 18 0
DDX20 DDX20 Q9UHI6 Probable ATP-dependent RNA helicase DDX20 chr1 Not Cancer Driver No 1 intact, hippie 89 299 33 33 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 72 342 30 30 0
DDX24 DDX24 Q9GZR7 ATP-dependent RNA helicase DDX24 chr14 Not Cancer Driver No 2 hippie, biogrid 86 452 40 40 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 Not Cancer Driver No 2 hippie, biogrid 99 342 38 38 0
DDX42 DDX42 Q86XP3 ATP-dependent RNA helicase DDX42 chr17 Not Cancer Driver No 1 hippie, biogrid 126 607 79 79 0
DDX51 DDX51 Q8N8A6 ATP-dependent RNA helicase DDX51 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 51 244 8 8 0
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 113 458 52 52 0
DDX56 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 50 107 13 13 0
DEAF1 DEAF1 O75398 Deformed epidermal autoregulatory factor 1 homolog chr11 Not Cancer Driver No 1 hippie 75 370 51 51 4
DGCR8 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 Census, Compendium Yes 2 intact, hippie, biogrid 102 466 57 57 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 203 702 78 78 4
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 Not Cancer Driver No 1 hippie 83 10 1 1 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 2 hippie, biogrid 59 188 22 22 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EPB41L2_ENST00000368128 EPB41L2 O43491 Band 4.1-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 157 708 113 113 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact 147 211 38 38 0
ESF1 ESF1 Q9H501 ESF1 homolog chr20 Not Cancer Driver No 1 hippie, biogrid 129 684 109 109 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 Not Cancer Driver No 1 intact, hippie 34 23 0 0 0
EYA3 EYA3 Q99504 Eyes absent homolog 3 chr1 Not Cancer Driver No 1 intact, hippie 58 310 40 40 0
EZH1 EZH1 Q92800 Histone-lysine N-methyltransferase EZH1 chr17 Not Cancer Driver No 1 hippie, biogrid 82 213 21 21 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FBL FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 Not Cancer Driver No 1 hippie, biogrid 46 145 22 22 0
FCF1 FCF1 Q9Y324 rRNA-processing protein FCF1 homolog chr14 Not Cancer Driver No 1 intact, hippie, biogrid 28 46 4 4 0
FGD1 FGD1 P98174 FYVE, RhoGEF and PH domain-containing protein 1 chrX Not Cancer Driver No 1 intact, hippie, biogrid 139 520 74 74 5
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 Not Cancer Driver No 1 hippie 33 411 24 24 32
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 Not Cancer Driver No 1 hippie 38 133 5 5 4
FOXI2 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 Not Cancer Driver No 1 intact, hippie 32 165 22 22 0
FOXR1 FOXR1 Q6PIV2 Forkhead box protein R1 chr11 Census Yes 1 intact, hippie 43 153 26 26 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 68 388 42 42 0
GNL2 GNL2 Q13823 Nucleolar GTP-binding protein 2 chr1 Not Cancer Driver No 2 hippie, biogrid 87 446 51 51 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 Not Cancer Driver No 1 hippie 33 80 6 6 0
GTPBP10 GTPBP10 A4D1E9 GTP-binding protein 10 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 50 52 4 4 0
GTPBP4 GTPBP4 Q9BZE4 GTP-binding protein 4 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 79 232 34 34 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 Not Cancer Driver No 1 intact 46 125 19 19 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 intact, hippie 65 61 8 8 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 348 845 195 195 4
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 40 352 40 40 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 Not Cancer Driver No 1 intact, hippie 154 686 96 96 0
HIRA HIRA P54198 Protein HIRA chr22 Not Cancer Driver No 2 intact, hippie, biogrid 138 288 37 37 0
HIST1H1T H1-6 P22492 Histone H1t chr6 Not Cancer Driver No 1 intact 49 158 38 38 0
HIST2H2BF_ENST00000369167 H2BC18 Q5QNW6 Histone H2B type 2-F chr1 Not Cancer Driver No 1 intact 33 77 23 23 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 hippie 25 203 20 20 0
HPDL HPDL Q96IR7 4-hydroxyphenylpyruvate dioxygenase-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 30 58 11 11 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 20
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
IQSEC1_ENST00000273221 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 141 610 97 97 2
ISY1_ENST00000393295 ISY1 Q9ULR0 Pre-mRNA-splicing factor ISY1 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 29 171 18 18 0
ITGB3BP_ENST00000271002 ITGB3BP Q13352 Centromere protein R chr1 Not Cancer Driver No 1 hippie, biogrid 19 122 14 14 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 intact, hippie 65 173 21 21 3
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 83 143 17 17 0
KPNA3 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 3 intact, hippie, biogrid 65 108 11 11 0
KPNA4 KPNA4 O00629 Importin subunit alpha-3 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 59 112 12 12 0
KRTAP8-1 KRTAP8-1 Q8IUC2 Keratin-associated protein 8-1 chr21 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
LBR_ENST00000272163 LBR Q14739 Delta(14)-sterol reductase LBR chr1 Not Cancer Driver No 1 hippie 95 130 15 15 5
LENG8 LENG8 Q96PV6 Leukocyte receptor cluster member 8 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 137 515 97 97 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie, biogrid 68 544 49 49 131
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 Not Cancer Driver No 1 hippie, biogrid 41 188 20 20 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 Not Cancer Driver No 1 hippie, biogrid 50 249 31 31 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MAX MAX P61244 Protein max chr14 Census, Compendium Yes 1 intact, hippie 45 160 45 45 9
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 76 446 42 42 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 54 176 19 19 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MFAP1 MFAP1 P55081 Microfibrillar-associated protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 58 377 53 53 0
MGARP MGARP Q8TDB4 Protein MGARP chr4 Not Cancer Driver No 1 intact, hippie 25 207 22 22 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 540 3169 529 529 0
MSH5_ENST00000375755 MSH5 O43196 MutS protein homolog 5 chr6 Not Cancer Driver No 1 intact, hippie 101 86 4 4 1
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 1 intact 104 8 1 1 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 Not Cancer Driver No 1 intact, hippie, biogrid 144 463 47 47 0
NAP1L3 NAP1L3 Q99457 Nucleosome assembly protein 1-like 3 chrX Not Cancer Driver No 1 intact, hippie 116 326 78 78 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 Not Cancer Driver No 1 intact, hippie, biogrid 109 142 18 18 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 hippie 352 2347 340 340 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 Not Cancer Driver No 1 hippie 92 285 39 39 12
NEPRO NEPRO Q6NW34 Nucleolus and neural progenitor protein chr3 Not Cancer Driver No 1 intact, hippie 62 147 28 28 0
NKAPD1_ENST00000420986 NKAPD1 Q6ZUT1 Uncharacterized protein NKAPD1 chr11 Not Cancer Driver No 1 intact, hippie 35 261 31 31 0
NKTR NKTR P30414 NK-tumor recognition protein chr3 Compendium Yes 1 hippie, biogrid 172 1299 153 153 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 60 21 3 3 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 2 hippie, biogrid 77 281 31 31 0
NOL6 NOL6 Q9H6R4 Nucleolar protein 6 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 156 176 26 26 0
NOL8_ENST00000442668 NOL8 Q76FK4 Nucleolar protein 8 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 127 978 109 109 0
NOP16_ENST00000614830 NOP16 Q9Y3C1 Nucleolar protein 16 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 19 118 12 12 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 intact, hippie, biogrid 116 510 72 72 0
NSD1 NSD1 Q96L73 Histone-lysine N-methyltransferase, H3 lysine-36 specific chr5 Census, Compendium Yes 2 hippie, biogrid 343 1864 206 206 14
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
NSRP1 NSRP1 Q9H0G5 Nuclear speckle splicing regulatory protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 61 521 56 56 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie, biogrid 21 37 3 3 0
NUFIP2 NUFIP2 Q7Z417 Nuclear fragile X mental retardation-interacting protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 67 623 62 62 0
NUP50 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 hippie, biogrid 58 333 40 40 0
NUSAP1 NUSAP1 Q9BXS6 Nucleolar and spindle-associated protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 49 415 42 42 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 2 intact, hippie, biogrid 90 267 31 31 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 Not Cancer Driver No 1 intact, hippie 124 537 87 87 0
PDCD11 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 2 intact, hippie, biogrid 212 487 64 64 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 1 hippie 80 241 43 43 0
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 Not Cancer Driver No 1 hippie, biogrid 56 123 15 15 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 Not Cancer Driver No 1 hippie, biogrid 161 495 75 75 3
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPIE_ENST00000324379 PPIE Q9UNP9 Peptidyl-prolyl cis-trans isomerase E chr1 Not Cancer Driver No 1 hippie, biogrid 51 102 17 17 0
PPIL4 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 Not Cancer Driver No 1 hippie, biogrid 62 237 34 34 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 Not Cancer Driver No 1 hippie, biogrid 114 798 100 100 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRPF38A PRPF38A Q8NAV1 Pre-mRNA-splicing factor 38A chr1 Not Cancer Driver No 1 hippie, biogrid 39 142 22 22 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PRPF40B_ENST00000380281 PRPF40B Q6NWY9 Pre-mRNA-processing factor 40 homolog B chr12 Census Yes 1 hippie 116 629 92 92 0
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX Not Cancer Driver No 1 hippie 50 0 0 0 14
PSPC1_ENST00000619300 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 1 hippie, biogrid 97 367 81 81 0
PWP2 PWP2 Q15269 Periodic tryptophan protein 2 homolog chr21 Not Cancer Driver No 2 intact, hippie, biogrid 99 101 9 9 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 174 291 99 99 0
RAB38 RAB38 P57729 Ras-related protein Rab-38 chr11 Not Cancer Driver No 1 intact, hippie 27 0 0 0 0
RASSF1 RASSF1 Q9NS23 Ras association domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 36 79 3 3 0
RASSF5 RASSF5 Q8WWW0 Ras association domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie 37 183 11 11 0
RBAK_ENST00000353796 RBAK Q9NYW8 RB-associated KRAB zinc finger protein chr7 Not Cancer Driver No 2 intact, hippie, biogrid 106 131 15 15 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 hippie, biogrid 124 549 88 88 0
RBM28 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 97 512 66 66 1
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 49 151 19 19 2
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 Not Cancer Driver No 1 hippie 47 324 28 28 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 Not Cancer Driver No 1 intact, hippie, biogrid 60 244 26 26 0
RIOX2_ENST00000394198 RIOX2 Q8IUF8 Ribosomal oxygenase 2 chr3 Not Cancer Driver No 1 intact, hippie 49 74 10 10 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 Not Cancer Driver No 1 intact, hippie 86 168 26 26 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 Not Cancer Driver No 1 intact, hippie 22 29 1 1 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPF1 RPF1 Q9H9Y2 Ribosome production factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 39 191 23 23 0
RPF2 RPF2 Q9H7B2 Ribosome production factor 2 homolog chr6 Not Cancer Driver No 2 intact, hippie, biogrid 37 92 9 9 0
RPL10A RPL10A P62906 60S ribosomal protein L10a chr6 Not Cancer Driver No 1 intact, hippie, biogrid 22 16 0 0 0
RPL12 RPL12 P30050 60S ribosomal protein L12 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 13 75 6 6 0
RPL13_ENST00000393099 RPL13 P26373 60S ribosomal protein L13 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 14 160 11 11 1
RPL15_ENST00000413699 RPL15 P61313 60S ribosomal protein L15 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 18 84 9 9 0
RPL17_ENST00000579248 RPL17 P18621 60S ribosomal protein L17 chr18 Not Cancer Driver No 1 hippie, biogrid 26 97 14 14 0
RPL18 RPL18 Q07020 60S ribosomal protein L18 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 16 98 6 6 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 21 107 11 11 0
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 21 13 3 3 0
RPL29_ENST00000475248 RPL29 P47914 60S ribosomal protein L29 chr3 Not Cancer Driver No 1 hippie, biogrid 9 159 9 9 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 34 79 3 3 0
RPL32_ENST00000435983 RPL32 P62910 60S ribosomal protein L32 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 11 75 5 5 0
RPL36_ENST00000347512 RPL36 Q9Y3U8 60S ribosomal protein L36 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 7 66 4 4 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 Census Yes 2 intact, hippie, biogrid 57 96 17 17 2
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 hippie, biogrid 41 159 24 24 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 2 intact, hippie, biogrid 27 100 5 5 0
RPL8_ENST00000528957 RPL8 P62917 60S ribosomal protein L8 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 32 115 17 17 0
RPLP2_ENST00000530797 RPLP2 P05387 60S acidic ribosomal protein P2 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 12 59 5 5 0
RPP40 RPP40 O75818 Ribonuclease P protein subunit p40 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 51 5 0 0 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie, biogrid 15 61 3 3 23
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 hippie, biogrid 38 150 25 25 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 23 81 7 7 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 2 intact, hippie, biogrid 74 513 48 48 0
RRP7A RRP7A Q9Y3A4 Ribosomal RNA-processing protein 7 homolog A chr22 Not Cancer Driver No 2 hippie, biogrid 25 97 14 14 1
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 66 270 44 44 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 71 685 63 63 0
SDAD1 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 Not Cancer Driver No 1 intact, hippie, biogrid 65 288 29 29 0
SH3BGRL SH3BGRL O75368 SH3 domain-binding glutamic acid-rich-like protein chrX Not Cancer Driver No 1 hippie, biogrid 23 51 8 8 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 2 intact, hippie 172 617 73 73 0
SIN3B SIN3B O75182 Paired amphipathic helix protein Sin3b chr19 Not Cancer Driver No 1 hippie 130 316 32 32 0
SKI SKI P12755 Ski oncogene chr1 Census Yes 1 hippie 44 432 26 26 14
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 2 intact, hippie 64 141 35 35 3
SMARCE1 SMARCE1 Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 chr17 Census Yes 1 hippie 47 332 36 36 2
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 1 hippie 149 605 70 70 0
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 hippie 2 181 2 2 0
SOX18 SOX18 P35713 Transcription factor SOX-18 chr20 Not Cancer Driver No 1 intact, hippie 10 321 10 10 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 Not Cancer Driver No 1 hippie, biogrid 136 680 101 101 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 Not Cancer Driver No 1 hippie 66 587 37 37 0
SPATA12 SPATA12 Q7Z6I5 Spermatogenesis-associated protein 12 chr3 Not Cancer Driver No 1 intact, hippie 15 68 5 5 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 Not Cancer Driver No 1 hippie 46 187 34 34 0
SPOUT1 SPOUT1 Q5T280 Putative methyltransferase C9orf114 chr9 Not Cancer Driver No 1 intact, hippie 35 166 18 18 0
SRBD1 SRBD1 Q8N5C6 S1 RNA-binding domain-containing protein 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 110 279 29 29 0
SRSF8 SRSF8 Q9BRL6 Serine/arginine-rich splicing factor 8 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 23 282 23 23 0
STX11 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 1 intact, hippie 71 48 7 7 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie, biogrid 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 59 15 1 1 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 21 111 2 2 0
TAF1A TAF1A Q15573 TATA box-binding protein-associated factor RNA polymerase I subunit A chr1 Not Cancer Driver No 2 intact, hippie, biogrid 49 27 4 4 0
TAF1B TAF1B Q53T94 TATA box-binding protein-associated factor RNA polymerase I subunit B chr2 Not Cancer Driver No 2 intact, hippie, biogrid 61 54 7 7 0
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 Not Cancer Driver No 2 hippie, biogrid 114 312 35 35 0
TAF1D TAF1D Q9H5J8 TATA box-binding protein-associated factor RNA polymerase I subunit D chr11 Not Cancer Driver No 2 hippie, biogrid 33 180 23 23 0
TBL1X TBL1X O60907 F-box-like/WD repeat-containing protein TBL1X chrX Not Cancer Driver No 1 hippie 85 181 35 35 0
TBL1XR1 TBL1XR1 Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 chr3 Census, Compendium Yes 1 hippie 82 136 19 19 4
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 Not Cancer Driver No 1 intact, hippie 66 220 31 31 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TEX10 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 115 103 12 12 0
TFB1M TFB1M Q8WVM0 Dimethyladenosine transferase 1, mitochondrial chr6 Not Cancer Driver No 2 hippie, biogrid 50 26 3 3 0
TMA16 TMA16 Q96EY4 Translation machinery-associated protein 16 chr4 Not Cancer Driver No 1 hippie, biogrid 25 112 10 10 0
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 Census, Compendium Yes 1 hippie, biogrid 93 391 53 53 0
TOP3A TOP3A Q13472 DNA topoisomerase 3-alpha chr17 Not Cancer Driver No 2 intact, hippie, biogrid 103 293 31 31 2
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIM69_ENST00000329464 TRIM69 Q86WT6 E3 ubiquitin-protein ligase TRIM69 chr15 Not Cancer Driver No 1 hippie 78 62 15 15 0
TRIM74 TRIM74 Q86UV6 Tripartite motif-containing protein 74 chr7 Not Cancer Driver No 1 hippie 25 12 1 1 0
TRIP12_ENST00000283943 TRIP12 Q14669 E3 ubiquitin-protein ligase TRIP12 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 224 845 117 117 4
TRMT1L TRMT1L Q7Z2T5 TRMT1-like protein chr1 Not Cancer Driver No 2 intact, hippie, biogrid 71 241 19 19 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 Not Cancer Driver No 1 intact, hippie 95 135 11 11 38
TXN TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie 6 0 0 0 0
URB1 URB1 O60287 Nucleolar pre-ribosomal-associated protein 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 93 180 2 2 0
URB2 URB2 Q14146 Unhealthy ribosome biogenesis protein 2 homolog chr1 Not Cancer Driver No 2 intact, hippie, biogrid 186 18 2 2 0
UTP23 UTP23 Q9BRU9 rRNA-processing protein UTP23 homolog chr8 Not Cancer Driver No 1 hippie, biogrid 35 97 16 16 0
WDR36 WDR36 Q8NI36 WD repeat-containing protein 36 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 140 89 11 11 2
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 105 203 10 10 39
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 Not Cancer Driver No 1 hippie, biogrid 128 127 17 17 0
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 Census, Compendium Yes 1 hippie, biogrid 88 479 48 48 2
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 hippie 41 312 41 41 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 2 hippie, biogrid 37 336 26 26 2
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 75 216 30 30 0
ZCCHC17_ENST00000373714 ZCCHC17 Q9NP64 Zinc finger CCHC domain-containing protein 17 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 25 153 16 16 0
ZNF263 ZNF263 O14978 Zinc finger protein 263 chr16 Not Cancer Driver No 1 hippie 90 403 58 58 0
ZNF330 ZNF330 Q9Y3S2 Zinc finger protein 330 chr4 Not Cancer Driver No 1 hippie, biogrid 44 127 19 19 0
ZNF354A ZNF354A O60765 Zinc finger protein 354A chr5 Not Cancer Driver No 1 hippie, biogrid 98 180 36 36 0
ZNF483 ZNF483 Q8TF39 Zinc finger protein 483 chr9 Not Cancer Driver No 2 hippie, biogrid 115 248 47 47 0
ZNF593 ZNF593 O00488 Zinc finger protein 593 chr1 Not Cancer Driver No 1 hippie, biogrid 9 117 8 8 0
ZNF800_ENST00000393312 ZNF800 Q2TB10 Zinc finger protein 800 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 108 397 72 72 0