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MARCKSL1 ,MARCKSL1 ,P49006
  • Uniprot Accession= P49006
  • Ensembl Transcript= ENST00000329421.7
  • Uniprot Name= MARCKSL1
  • Name= MARCKS-related protein
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 29
  • Number of Interaction partner in biogrid: 58
  • Number of Interaction partner in hippie: 98
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ATP11C ATP11C Q8NB49 Phospholipid-transporting ATPase IG chrX Not Cancer Driver No 1 intact, hippie, biogrid 198 32 5 5 1
ATP6V0A1_ENST00000343619 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 Not Cancer Driver No 2 hippie, biogrid 98 85 14 14 0
ATP6V0A2 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 Not Cancer Driver No 2 hippie, biogrid 88 36 6 6 0
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 86 31 2 2 4
ATP6V1D ATP6V1D Q9Y5K8 V-type proton ATPase subunit D chr14 Not Cancer Driver No 1 hippie, biogrid 28 14 2 2 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCCIP_ENST00000278100 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 Not Cancer Driver No 2 intact, hippie, biogrid 35 99 16 16 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 42 212 19 19 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 1 hippie 46 253 32 32 0
DNAJB14 DNAJB14 Q8TBM8 DnaJ homolog subfamily B member 14 chr4 Not Cancer Driver No 1 hippie, biogrid 38 200 19 19 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie, biogrid 23 46 6 6 1
DNAJC5B DNAJC5B Q9UF47 DnaJ homolog subfamily C member 5B chr8 Not Cancer Driver No 1 hippie, biogrid 64 31 7 7 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact 147 211 38 38 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 Not Cancer Driver No 1 hippie, biogrid 106 459 54 54 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 87 373 36 36 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie, biogrid 107 16 4 4 18
KBTBD7 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 92 105 6 6 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 2 hippie, biogrid 47 93 10 10 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 Not Cancer Driver No 1 intact, hippie 134 39 4 4 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 104 333 66 66 6
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MRM3 MRM3 Q9HC36 rRNA methyltransferase 3, mitochondrial chr17 Not Cancer Driver No 1 hippie 45 83 8 8 0
MRPL16 MRPL16 Q9NX20 39S ribosomal protein L16, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 38 57 11 11 0
MRPL22 MRPL22 Q9NWU5 39S ribosomal protein L22, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 23 28 2 2 0
MRPL30 MRPL30 Q8TCC3 39S ribosomal protein L30, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 29 75 11 11 0
MRPL46 MRPL46 Q9H2W6 39S ribosomal protein L46, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 24 58 0 0 0
MYLK4 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 67 77 14 14 0
NDUFB5 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 28 9 1 1 0
NMT1_ENST00000258960 NMT1 P30419 Glycylpeptide N-tetradecanoyltransferase 1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 62 169 22 22 0
NMT2 NMT2 O60551 Glycylpeptide N-tetradecanoyltransferase 2 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 60 154 20 20 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie, biogrid 146 211 31 31 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PCDH7_ENST00000361762 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 hippie, biogrid 167 550 76 76 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PPP4R2 PPP4R2 Q9NY27 Serine/threonine-protein phosphatase 4 regulatory subunit 2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 32 314 26 26 0
PPP4R3A_ENST00000554943 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 Not Cancer Driver No 1 intact, hippie 89 255 29 29 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie, biogrid 53 24 0 0 2
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie, biogrid 70 116 11 11 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 49 140 25 25 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RALA RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie, biogrid 34 34 3 3 5
RALB RALB P11234 Ras-related protein Ral-B chr2 Not Cancer Driver No 1 hippie, biogrid 36 35 5 5 0
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 30 8 1 1 4
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 34 63 6 6 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie, biogrid 119 232 34 34 3
RMI1 RMI1 Q9H9A7 RecQ-mediated genome instability protein 1 chr9 Not Cancer Driver No 2 hippie, biogrid 67 243 26 26 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 Not Cancer Driver No 1 hippie 133 91 15 15 0
SCRN2 SCRN2 Q96FV2 Secernin-2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 65 145 24 24 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 intact, hippie 110 440 72 72 0
SNX21 SNX21 Q969T3 Sorting nexin-21 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 29 174 14 14 0
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 49 4 4 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 16 93 9 9 79
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 Not Cancer Driver No 1 hippie 47 25 2 2 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM216 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 11 0 0 0 7
TMEM63B TMEM63B Q5T3F8 CSC1-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 108 78 12 12 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOP3A TOP3A Q13472 DNA topoisomerase 3-alpha chr17 Not Cancer Driver No 2 intact, hippie, biogrid 103 293 31 31 2
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 intact, hippie, biogrid 120 537 61 61 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 75 216 30 30 0
ZBTB43_ENST00000449886 ZBTB43 O43298 Zinc finger and BTB domain-containing protein 43 chr9 Not Cancer Driver No 1 hippie, biogrid 56 252 33 33 0