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LUZP1_ENST00000418342 ,LUZP1 ,Q86V48
  • Uniprot Accession= Q86V48
  • Ensembl Transcript= ENST00000418342.5
  • Uniprot Name= LUZP1
  • Name= Leucine zipper protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 53
  • Number of Interaction partner in biogrid: 37
  • Number of Interaction partner in hippie: 143
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAK1 AAK1 Q2M2I8 AP2-associated protein kinase 1 chr2 Not Cancer Driver No 2 intact, hippie 109 654 70 70 0
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 40 157 20 20 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 6 2 2 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BORCS6 BORCS6 Q96GS4 BLOC-1-related complex subunit 6 chr17 Not Cancer Driver No 2 intact, hippie 17 269 11 11 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 intact, hippie 224 1458 174 174 35
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 Not Cancer Driver No 1 hippie 90 399 45 45 4
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 176 1025 127 127 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CARNMT1 CARNMT1 Q8N4J0 Carnosine N-methyltransferase chr9 Not Cancer Driver No 2 intact, hippie 42 75 1 1 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 Not Cancer Driver No 2 intact, hippie 226 1481 173 173 0
CDC14A_ENST00000336454 CDC14A Q9UNH5 Dual specificity protein phosphatase CDC14A chr1 Not Cancer Driver No 1 intact, hippie 91 246 43 43 3
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
CEP104 CEP104 O60308 Centrosomal protein of 104 kDa chr1 Not Cancer Driver No 1 hippie 116 306 43 43 0
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 102 448 52 52 1
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 2 hippie, biogrid 127 690 72 72 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 204 986 110 110 2
CEP162 CEP162 Q5TB80 Centrosomal protein of 162 kDa chr6 Not Cancer Driver No 1 intact, hippie 162 1056 128 128 0
CEP170 CEP170 Q5SW79 Centrosomal protein of 170 kDa chr1 Not Cancer Driver No 1 intact, hippie 264 1429 246 246 0
CEP290 CEP290 O15078 Centrosomal protein of 290 kDa chr12 Not Cancer Driver No 1 intact, hippie 255 1421 152 152 3
CEP63 CEP63 Q96MT8 Centrosomal protein of 63 kDa chr3 Not Cancer Driver No 1 intact, hippie 100 507 68 68 0
CEP89 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 1 hippie 96 540 72 72 0
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 Not Cancer Driver No 1 hippie 50 173 7 7 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 234 1556 159 159 0
CNTROB_ENST00000563694 CNTROB Q8N137 Centrobin chr17 Not Cancer Driver No 1 intact, hippie 97 837 93 93 0
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CUL5 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact, hippie 97 5 1 1 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 56 82 7 7 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 2 intact, hippie, biogrid 172 817 111 111 11
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 Not Cancer Driver No 3 intact, hippie, biogrid 55 0 0 0 6
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 70 273 34 34 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EYA4_ENST00000367895 EYA4 O95677 Eyes absent homolog 4 chr6 Not Cancer Driver No 2 intact, hippie 183 337 108 108 2
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie, biogrid 66 295 35 35 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 1 hippie 68 120 4 4 0
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 hippie, biogrid 275 915 180 180 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 hippie 124 327 70 70 3
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 hippie 68 388 42 42 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 hippie, biogrid 65 288 42 42 62
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
HAUS3 HAUS3 Q68CZ6 HAUS augmin-like complex subunit 3 chr4 Not Cancer Driver No 1 hippie, biogrid 61 55 7 7 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie 79 493 55 55 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 24 200 13 13 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 20
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
KIAA0753 KIAA0753 Q2KHM9 Protein moonraker chr17 Not Cancer Driver No 1 intact, hippie 109 647 82 82 0
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 intact, hippie 90 389 26 26 4
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF2A_ENST00000401507 KIF2A O00139 Kinesin-like protein KIF2A chr5 Not Cancer Driver No 1 hippie, biogrid 74 336 37 37 2
KLHDC3 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 Not Cancer Driver No 2 hippie, biogrid 43 12 1 1 0
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 Not Cancer Driver No 1 hippie, biogrid 57 165 19 19 0
KXD1_ENST00000222307 KXD1 Q9BQD3 KxDL motif-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 24 104 17 17 0
LCA5 LCA5 Q86VQ0 Lebercilin chr6 Not Cancer Driver No 1 intact, hippie 102 597 82 82 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LUZP4 LUZP4 Q9P127 Leucine zipper protein 4 chrX Not Cancer Driver No 1 hippie 74 313 74 74 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie, biogrid 26 12 1 1 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 Not Cancer Driver No 1 hippie 78 243 23 23 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 2 hippie, biogrid 26 109 11 11 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 37 120 16 16 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 hippie, biogrid 136 589 92 92 0
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie 29 161 17 17 0
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 Not Cancer Driver No 2 hippie, biogrid 33 95 7 7 1
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie 122 282 34 34 1
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 1 hippie, biogrid 80 313 45 45 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 intact, hippie 230 881 150 150 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
ODF2 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 intact, hippie 123 607 90 90 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 2 intact, hippie, biogrid 152 1665 134 134 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 48 244 20 20 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 2 intact, hippie 677 2130 272 272 2
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
POC1A POC1A Q8NBT0 POC1 centriolar protein homolog A chr3 Not Cancer Driver No 1 hippie 51 88 8 8 1
PPIP5K2_ENST00000358359 PPIP5K2 O43314 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 chr5 Not Cancer Driver No 2 intact, hippie 146 419 54 54 1
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 177 586 94 94 8
SCGN SCGN O76038 Secretagogin chr6 Not Cancer Driver No 1 hippie, biogrid 77 12 1 1 0
SCLT1 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 intact, hippie 98 398 61 61 0
SCOC SCOC Q9UIL1 Short coiled-coil protein chr4 Not Cancer Driver No 2 intact, hippie, biogrid 13 82 8 8 0
SEC24B_ENST00000265175 SEC24B O95487 Protein transport protein Sec24B chr4 Not Cancer Driver No 2 intact, hippie 135 526 55 55 0
SEC31A_ENST00000355196 SEC31A O94979 Protein transport protein Sec31A chr4 Not Cancer Driver No 1 intact, hippie 139 519 58 58 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SPICE1 SPICE1 Q8N0Z3 Spindle and centriole-associated protein 1 chr3 Not Cancer Driver No 1 hippie 112 729 92 92 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 intact, hippie 82 265 31 31 0
SYCE1_ENST00000343131 SYCE1 Q8N0S2 Synaptonemal complex central element protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 70 251 50 50 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TCTE1 TCTE1 Q5JU00 Dynein regulatory complex subunit 5 chr6 Not Cancer Driver No 1 hippie 101 125 20 20 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 149 919 113 113 1
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 hippie, biogrid 48 229 28 28 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 Not Cancer Driver No 1 hippie 38 81 12 12 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 Not Cancer Driver No 1 hippie, biogrid 106 89 21 21 1
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 Not Cancer Driver No 1 hippie 71 176 27 27 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 Compendium Yes 1 hippie 19 13 1 1 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 3 intact, hippie, biogrid 22 109 4 4 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 intact, hippie, biogrid 15 55 3 3 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZMYND8_ENST00000311275 ZMYND8 Q9ULU4 Protein kinase C-binding protein 1 chr20 Not Cancer Driver No 1 hippie 176 830 124 124 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 83 385 52 52 0