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LRP8 ,LRP8 ,Q14114
  • Number of Interaction partner in intact: 5
  • Number of Interaction partner in biogrid: 19
  • Number of Interaction partner in hippie: 81
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALB ALB P02768 Albumin chr4 Compendium Yes 1 hippie 162 6 0 0 3
ANAPC10_ENST00000507656 ANAPC10 Q9UM13 Anaphase-promoting complex subunit 10 chr4 Not Cancer Driver No 1 hippie 12 65 0 0 0
ANGEL2 ANGEL2 Q5VTE6 Protein angel homolog 2 chr1 Not Cancer Driver No 1 hippie 56 48 6 6 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
APBA1 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 Not Cancer Driver No 1 hippie 149 556 103 103 0
APBA2_ENST00000561069 APBA2 Q99767 Amyloid-beta A4 precursor protein-binding family A member 2 chr15 Not Cancer Driver No 1 hippie 184 429 117 117 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 hippie 412 2406 345 345 22
APLP2 APLP2 Q06481 Amyloid beta precursor like protein 2 chr11 Not Cancer Driver No 1 intact, hippie 96 393 48 48 0
APOE APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 2 intact, hippie 25 124 6 6 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 Not Cancer Driver No 1 hippie 67 0 0 0 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ARHGAP39_ENST00000276826 ARHGAP39 Q9C0H5 Rho GTPase-activating protein 39 chr8 Not Cancer Driver No 1 hippie 120 613 61 61 0
C19orf47 C19orf47 Q8N9M1 Uncharacterized protein C19orf47 chr19 Not Cancer Driver No 1 hippie 41 301 30 30 0
CAMSAP3_ENST00000160298 CAMSAP3 Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 chr19 Not Cancer Driver No 1 hippie 132 889 81 81 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 Not Cancer Driver No 1 hippie 69 156 27 27 0
CRCT1 CRCT1 Q9UGL9 Cysteine-rich C-terminal protein 1 chr1 Not Cancer Driver No 1 hippie 18 19 6 6 0
CRTC3 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 Census Yes 1 hippie 70 608 68 68 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 hippie 59 132 16 16 2
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 Not Cancer Driver No 1 hippie 200 393 143 143 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 Not Cancer Driver No 1 hippie 144 680 125 125 0
DENND6A DENND6A Q8IWF6 Protein DENND6A chr3 Not Cancer Driver No 1 hippie, biogrid 54 69 2 2 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 Not Cancer Driver No 1 hippie 116 232 55 55 0
DOCK6 DOCK6 Q96HP0 Dedicator of cytokinesis protein 6 chr19 Not Cancer Driver No 1 hippie 203 496 57 57 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
GGA1 GGA1 Q9UJY5 ADP-ribosylation factor-binding protein GGA1 chr22 Not Cancer Driver No 1 hippie 75 385 33 33 0
GHDC_ENST00000587427 GHDC Q8N2G8 GH3 domain-containing protein chr17 Not Cancer Driver No 1 hippie 49 111 11 11 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 Not Cancer Driver No 1 hippie 47 138 17 17 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 Not Cancer Driver No 1 hippie 88 190 15 15 13
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 Not Cancer Driver No 1 hippie 26 58 11 11 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 intact, hippie 65 173 21 21 3
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 Census, Compendium Yes 1 hippie 357 275 55 55 2
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 788 7 2 2 27
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie 65 221 37 37 3
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 Not Cancer Driver No 1 hippie 94 190 24 24 0
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 Not Cancer Driver No 3 hippie, biogrid 41 188 20 20 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 Not Cancer Driver No 1 hippie 79 444 40 40 1
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 Not Cancer Driver No 1 hippie 49 568 27 27 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 Not Cancer Driver No 1 hippie 15 20 2 2 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 Not Cancer Driver No 1 hippie 56 11 2 2 0
NECAB3 NECAB3 Q96P71 N-terminal EF-hand calcium-binding protein 3 chr20 Not Cancer Driver No 1 intact, hippie 39 169 17 17 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 Not Cancer Driver No 1 intact 92 285 39 39 12
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 Not Cancer Driver No 1 hippie 94 255 53 53 1
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie 284 10 0 0 14
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PPP1R9A_ENST00000433881 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 1 hippie 217 887 174 174 0
PRCC PRCC Q92733 Proline-rich protein PRCC chr1 Census Yes 1 hippie 58 469 57 57 0
PRKRIP1_ENST00000397912 PRKRIP1 Q9H875 PRKR-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 22 184 22 22 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie, biogrid 36 25 6 6 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 18 21 1 1 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 Not Cancer Driver No 1 hippie 42 47 5 5 3
RELN RELN P78509 Reelin chr7 Not Cancer Driver No 1 hippie 761 107 19 19 7
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
SCN3A_ENST00000360093 SCN3A Q9NY46 Sodium channel protein type 3 subunit alpha chr2 Not Cancer Driver No 1 hippie 415 432 83 83 6
SNX17 SNX17 Q15036 Sorting nexin-17 chr2 Not Cancer Driver No 1 hippie 55 118 10 10 0
SS18 SS18 Q15532 Protein SSXT chr18 Census Yes 1 hippie 52 416 52 52 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 Not Cancer Driver No 1 hippie 27 12 4 4 0
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 hippie 51 399 46 46 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 hippie 22 14 2 2 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TXN TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie 6 0 0 0 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 1 hippie 148 213 29 29 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VLDLR VLDLR P98155 Very low-density lipoprotein receptor chr9 Not Cancer Driver No 1 hippie 90 55 3 3 0