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LHX8 ,LHX8 ,Q68G74
  • Uniprot Accession= Q68G74
  • Ensembl Transcript= ENST00000294638.9
  • Uniprot Name= LHX8
  • Name= LIM/homeobox protein Lhx8
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 40
  • Number of Interaction partner in biogrid: 3
  • Number of Interaction partner in hippie: 61
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 intact, hippie 56 361 38 38 0
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 Census, Compendium Yes 1 hippie 272 1143 141 141 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 65 451 58 58 0
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 Not Cancer Driver No 1 intact, hippie 70 557 59 59 0
AXIN1 AXIN1 O15169 Axin-1 chr16 Census, Compendium Yes 1 intact, hippie 120 619 88 88 4
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 intact, hippie 74 311 43 43 0
BCL9 BCL9 O00512 B-cell CLL/lymphoma 9 protein chr1 Census, Compendium Yes 1 hippie 219 1426 219 219 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
CCHCR1_ENST00000376266 CCHCR1 Q8TD31 Coiled-coil alpha-helical rod protein 1 chr6 Not Cancer Driver No 1 hippie 116 565 88 88 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 intact, hippie 83 72 10 10 1
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 intact, hippie 71 75 8 8 4
DMWD DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 intact 66 374 24 24 0
DPF1_ENST00000456296 DPF1 Q92782 Zinc finger protein neuro-d4 chr19 Not Cancer Driver No 1 hippie 32 85 7 7 0
ECH1 ECH1 Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 35 23 2 2 0
EFS EFS O43281 Embryonal Fyn-associated substrate chr14 Not Cancer Driver No 1 hippie 74 414 57 57 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 173 241 26 26 37
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 Not Cancer Driver No 2 intact, hippie, biogrid 22 154 17 17 0
FOSL2 FOSL2 P15408 Fos-related antigen 2 chr2 Not Cancer Driver No 1 intact, hippie 54 323 54 54 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 Not Cancer Driver No 1 intact, hippie 90 483 65 65 2
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 Not Cancer Driver No 1 hippie 32 77 14 14 0
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 intact, hippie 64 299 29 29 3
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 intact, hippie 111 276 6 6 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GRPEL1 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie 22 88 7 7 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
ISL2 ISL2 Q96A47 Insulin gene enhancer protein ISL-2 chr15 Not Cancer Driver No 1 intact, hippie 42 167 16 16 0
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 intact, hippie 253 633 106 106 1
KLF3 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 2 intact, hippie 53 243 38 38 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 1 intact, hippie 773 4386 552 552 13
KRT85 KRT85 P78386 Keratin, type II cuticular Hb5 chr12 Not Cancer Driver No 1 hippie 97 29 4 4 1
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 Compendium Yes 2 intact, hippie 56 177 29 29 0
LDB2 LDB2 O43679 LIM domain-binding protein 2 chr4 Not Cancer Driver No 1 intact, hippie 122 145 54 54 0
LHX6_ENST00000373755 LHX6 Q9UPM6 LIM/homeobox protein Lhx6 chr9 Not Cancer Driver No 1 intact, hippie 36 134 10 10 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 1 intact 26 384 25 25 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 Not Cancer Driver No 1 intact, hippie 106 516 72 72 0
NUTM1_ENST00000614490 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 intact, hippie 202 967 175 175 0
PBRM1_ENST00000296302 PBRM1 Q86U86 Protein polybromo-1 chr3 Census, Compendium Yes 1 hippie 209 703 77 77 0
PCGF1 PCGF1 Q9BSM1 Polycomb group RING finger protein 1 chr2 Not Cancer Driver No 1 hippie 28 8 0 0 0
PEX1 PEX1 O43933 Peroxisome biogenesis factor 1 chr7 Not Cancer Driver No 1 hippie 143 304 36 36 14
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 Not Cancer Driver No 1 intact 37 4 1 1 0
PHF10 PHF10 Q8WUB8 PHD finger protein 10 chr6 Not Cancer Driver No 1 hippie 39 298 26 26 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 248 142 30 30 1
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 58 213 17 17 2
PYGO1 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 71 362 60 60 0
PYGO2 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 Not Cancer Driver No 1 intact, hippie 51 340 43 43 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
SCYL3_ENST00000367770 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 Not Cancer Driver No 1 intact, hippie 81 249 28 28 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SMARCD2 SMARCD2 Q92925 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 chr17 Not Cancer Driver No 1 hippie 58 251 26 26 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 71 194 35 35 2
SSBP2_ENST00000320672 SSBP2 P81877 Single-stranded DNA-binding protein 2 chr5 Not Cancer Driver No 1 hippie 36 296 29 29 0
SSBP3 SSBP3 Q9BWW4 Single-stranded DNA-binding protein 3 chr1 Not Cancer Driver No 1 intact, hippie 51 321 42 42 0
SSBP4 SSBP4 Q9BWG4 Single-stranded DNA-binding protein 4 chr19 Not Cancer Driver No 4 intact, hippie, biogrid 32 316 21 21 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 intact, hippie 59 15 1 1 0
TBC1D1 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 Not Cancer Driver No 1 intact, hippie 138 455 58 58 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 1 intact, hippie 55 205 27 27 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie 25 110 15 15 1
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 intact, hippie 111 381 53 53 0
TSC1 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 intact 135 732 78 78 11
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 105 203 10 10 39
ZBTB24 ZBTB24 O43167 Zinc finger and BTB domain-containing protein 24 chr6 Not Cancer Driver No 1 hippie 71 383 43 43 1
ZNF609 ZNF609 O15014 Zinc finger protein 609 chr15 Not Cancer Driver No 1 intact, hippie 141 1333 133 133 0