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LEPR ,LEPR ,P48357
  • Uniprot Accession= P48357
  • Ensembl Transcript= ENST00000349533.10
  • Uniprot Name= LEPR
  • Name= Leptin receptor
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 6
  • Number of Interaction partner in biogrid: 12
  • Number of Interaction partner in hippie: 40
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 Not Cancer Driver No 1 hippie, biogrid 100 183 24 24 0
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 21 30 1 1 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 127 521 71 71 2
APOD APOD P05090 Apolipoprotein D chr3 Not Cancer Driver No 1 hippie 34 13 2 2 0
AS3MT AS3MT Q9HBK9 Arsenite methyltransferase chr10 Not Cancer Driver No 1 hippie, biogrid 36 4 0 0 0
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 2 hippie, biogrid 40 0 0 0 0
BTNL8 BTNL8 Q6UX41 Butyrophilin-like protein 8 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 132 84 22 22 0
CDCP1 CDCP1 Q9H5V8 CUB domain-containing protein 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 113 161 26 26 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 Not Cancer Driver No 1 hippie 69 156 27 27 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 20 19 0 0 4
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 Not Cancer Driver No 1 hippie 87 410 42 42 0
FAM19A2_ENST00000551619 TAFA2 Q8N3H0 Chemokine-like protein TAFA-2 chr12 Not Cancer Driver No 1 hippie 55 4 1 1 0
FAM19A4 TAFA4 Q96LR4 Chemokine-like protein TAFA-4 chr3 Not Cancer Driver No 1 intact, hippie 38 4 1 1 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 Not Cancer Driver No 1 hippie 85 4 0 0 2
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HCRTR1 HCRTR1 O43613 Orexin/Hypocretin receptor type 1 chr1 Not Cancer Driver No 1 hippie 52 28 0 0 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 167 63 10 10 7
LEP LEP P41159 Leptin chr7 Not Cancer Driver No 2 hippie, biogrid 29 0 0 0 2
LEPR LEPR P48357 Leptin receptor chr1 Not Cancer Driver No 2 intact, hippie 243 57 11 11 0
LEPROT_ENST00000371065 LEPROT O15243 Leptin receptor gene-related protein chr1 Not Cancer Driver No 1 hippie 16 0 0 0 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 hippie 123 117 42 42 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie, biogrid 17 115 12 12 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie 129 260 38 38 60
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 Census, Compendium Yes 1 hippie 315 462 107 107 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 Not Cancer Driver No 1 hippie 184 401 61 61 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 hippie 44 33 2 2 0
SCGB1D1 SCGB1D1 O95968 Secretoglobin family 1D member 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 22 0 0 0 0
SERPINI2_ENST00000476257 SERPINI2 O75830 Serpin I2 chr3 Not Cancer Driver No 1 hippie, biogrid 116 21 10 10 0
SLURP1 SLURP1 P55000 Secreted Ly-6/uPAR-related protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 8
SNX1_ENST00000559844 SNX1 Q13596 Sorting nexin-1 chr15 Not Cancer Driver No 1 hippie 61 214 25 25 0
SNX2 SNX2 O60749 Sorting nexin-2 chr5 Not Cancer Driver No 1 hippie 45 218 18 18 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 Not Cancer Driver No 1 hippie 31 101 5 5 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 Not Cancer Driver No 1 hippie 33 85 7 7 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 Not Cancer Driver No 1 hippie 27 111 14 14 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
UBC UBC P0CG48 Polyubiquitin-C chr12 Not Cancer Driver No 1 intact 97 312 53 53 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 Census, Compendium Yes 1 hippie 122 602 69 69 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 Not Cancer Driver No 1 hippie 213 577 65 65 0