Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKAP8L | AKAP8L | Q9ULX6 | A-kinase anchor protein 8-like | chr19 | Not Cancer Driver | No | 1 | hippie | 76 | 510 | 61 | 61 | 0 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
| ARHGAP19 | ARHGAP19 | Q14CB8 | Rho GTPase-activating protein 19 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 179 | 21 | 21 | 0 |
| ARHGAP36 | ARHGAP36 | Q6ZRI8 | Rho GTPase-activating protein 36 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 194 | 132 | 61 | 61 | 0 |
| ARHGEF16 | ARHGEF16 | Q5VV41 | Rho guanine nucleotide exchange factor 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 297 | 13 | 13 | 0 |
| ARHGEF17 | ARHGEF17 | Q96PE2 | Rho guanine nucleotide exchange factor 17 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 237 | 1408 | 170 | 170 | 0 |
| ARHGEF39 | ARHGEF39 | Q8N4T4 | Rho guanine nucleotide exchange factor 39 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 56 | 5 | 5 | 0 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 46 | 122 | 22 | 22 | 0 |
| ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
| B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
| BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
| BHLHA15 | BHLHA15 | Q7RTS1 | Class A basic helix-loop-helix protein 15 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 12 | 183 | 12 | 12 | 0 |
| BHLHE23_ENST00000370346 | BHLHE23 | Q8NDY6 | Class E basic helix-loop-helix protein 23 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 119 | 9 | 9 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 150 | 30 | 30 | 0 |
| BRD7_ENST00000394688 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | Compendium | Yes | 1 | hippie | 82 | 482 | 57 | 57 | 0 |
| BRD9 | BRD9 | Q9H8M2 | Bromodomain-containing protein 9 | chr5 | Not Cancer Driver | No | 1 | hippie | 77 | 385 | 44 | 44 | 0 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 14 | 103 | 6 | 6 | 2 |
| CALD1 | CALD1 | Q05682 | Caldesmon | chr7 | Not Cancer Driver | No | 1 | hippie | 133 | 793 | 133 | 133 | 0 |
| CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 334 | 38 | 38 | 0 |
| CBX1_ENST00000225603 | CBX1 | P83916 | Chromobox protein homolog 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 31 | 154 | 25 | 25 | 0 |
| CBX3_ENST00000396386 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 119 | 18 | 18 | 0 |
| CBX5 | CBX5 | P45973 | Chromobox protein homolog 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 21 | 116 | 12 | 12 | 0 |
| CD274 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | Census | Yes | 1 | hippie | 29 | 54 | 9 | 9 | 0 |
| CD81 | CD81 | P60033 | CD81 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 0 | 0 | 0 | 0 |
| CDC34 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 95 | 11 | 11 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
| CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
| CDK20 | CDK20 | Q8IZL9 | Cyclin-dependent kinase 20 | chr9 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 1 | 1 | 0 |
| CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 34 | 2 | 2 | 0 |
| CHCHD2 | CHCHD2 | Q9Y6H1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 114 | 21 | 21 | 1 |
| CHTOP_ENST00000368694 | CHTOP | Q9Y3Y2 | Chromatin target of PRMT1 protein | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 244 | 34 | 34 | 0 |
| CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 409 | 55 | 55 | 0 |
| CLEC3A | CLEC3A | O75596 | C-type lectin domain family 3 member A | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 65 | 21 | 3 | 3 | 0 |
| CLK3 | CLK3 | P49761 | Dual specificity protein kinase CLK3 | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 67 | 295 | 27 | 27 | 0 |
| COPE_ENST00000262812 | COPE | O14579 | Coatomer subunit epsilon | chr19 | Not Cancer Driver | No | 1 | hippie | 29 | 47 | 6 | 6 | 0 |
| CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | Not Cancer Driver | No | 1 | hippie | 44 | 46 | 3 | 3 | 0 |
| CTCF | CTCF | P49711 | Transcriptional repressor CTCF | chr16 | Census, Compendium | Yes | 1 | hippie | 151 | 481 | 83 | 83 | 1 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
| DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
| DDX54_ENST00000306014 | DDX54 | Q8TDD1 | ATP-dependent RNA helicase DDX54 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 113 | 458 | 52 | 52 | 0 |
| DEPDC1B | DEPDC1B | Q8WUY9 | DEP domain-containing protein 1B | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 52 | 6 | 6 | 0 |
| DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 11 | 1 | 1 | 0 |
| DHFR2_ENST00000314636 | DHFR2 | Q86XF0 | Dihydrofolate reductase 2, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 25 | 20 | 0 | 0 | 0 |
| DHX15 | DHX15 | O43143 | ATP-dependent RNA helicase DHX15 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 110 | 180 | 30 | 30 | 0 |
| DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | hippie, biogrid | 182 | 331 | 42 | 42 | 0 |
| DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 190 | 32 | 32 | 1 |
| DNAJC1 | DNAJC1 | Q96KC8 | DnaJ homolog subfamily C member 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 315 | 44 | 44 | 0 |
| DNAJC16 | DNAJC16 | Q9Y2G8 | DnaJ homolog subfamily C member 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 63 | 2 | 2 | 0 |
| DNAJC25 | DNAJC25 | Q9H1X3 | DnaJ homolog subfamily C member 25 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 39 | 3 | 3 | 0 |
| DOCK9 | DOCK9 | Q9BZ29 | Dedicator of cytokinesis protein 9 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 236 | 180 | 20 | 20 | 0 |
| EED_ENST00000263360 | EED | O75530 | Polycomb protein EED | chr11 | Census | Yes | 1 | hippie | 64 | 79 | 11 | 11 | 6 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EIF4A3 | EIF4A3 | P38919 | Eukaryotic initiation factor 4A-III | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 57 | 6 | 6 | 1 |
| ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 25 | 4 | 4 | 2 |
| EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
| ERH | ERH | P84090 | Enhancer of rudimentary homolog | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 11 | 0 | 0 | 0 |
| EVC2 | EVC2 | Q86UK5 | Limbin | chr4 | Not Cancer Driver | No | 1 | hippie | 240 | 335 | 71 | 71 | 2 |
| FAM20C | FAM20C | Q8IXL6 | Extracellular serine/threonine protein kinase FAM20C | chr7 | Not Cancer Driver | No | 1 | hippie | 33 | 188 | 3 | 3 | 9 |
| FBL | FBL | P22087 | rRNA 2'-O-methyltransferase fibrillarin | chr19 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 22 | 22 | 0 |
| FBXO32 | FBXO32 | Q969P5 | F-box only protein 32 | chr8 | Not Cancer Driver | No | 1 | hippie | 54 | 0 | 0 | 0 | 0 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 160 | 25 | 25 | 0 |
| FNBP4 | FNBP4 | Q8N3X1 | Formin-binding protein 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 119 | 926 | 106 | 106 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 70 | 13 | 13 | 0 |
| G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 352 | 65 | 65 | 0 |
| GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
| GNLY_ENST00000263863 | GNLY | P22749 | Granulysin | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 19 | 1 | 1 | 0 |
| GOLT1B | GOLT1B | Q9Y3E0 | Vesicle transport protein GOT1B | chr12 | Not Cancer Driver | No | 1 | hippie | 26 | 0 | 0 | 0 | 0 |
| HAUS2 | HAUS2 | Q9NVX0 | HAUS augmin-like complex subunit 2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 8 | 0 | 0 | 0 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 182 | 749 | 132 | 132 | 0 |
| HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 40 | 352 | 40 | 40 | 0 |
| HIPK4 | HIPK4 | Q8NE63 | Homeodomain-interacting protein kinase 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 258 | 23 | 23 | 0 |
| HNRNPR_ENST00000374612 | HNRNPR | O43390 | Heterogeneous nuclear ribonucleoprotein R | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 304 | 25 | 25 | 0 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 504 | 45 | 45 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
| HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
| HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 118 | 8 | 8 | 20 |
| ILF2 | ILF2 | Q12905 | Interleukin enhancer-binding factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 92 | 9 | 9 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
| KCND3 | KCND3 | Q9UK17 | Potassium voltage-gated channel subfamily D member 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 172 | 202 | 44 | 44 | 5 |
| KLF15 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | Not Cancer Driver | No | 1 | hippie | 66 | 273 | 48 | 48 | 0 |
| KLF16 | KLF16 | Q9BXK1 | Krueppel-like factor 16 | chr19 | Not Cancer Driver | No | 1 | hippie | 13 | 204 | 8 | 8 | 0 |
| KLF8 | KLF8 | O95600 | Krueppel-like factor 8 | chrX | Not Cancer Driver | No | 1 | hippie | 71 | 270 | 53 | 53 | 0 |
| KLHL20 | KLHL20 | Q9Y2M5 | Kelch-like protein 20 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 143 | 17 | 17 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 47 | 93 | 10 | 10 | 0 |
| LAMP2_ENST00000200639 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 55 | 7 | 7 | 1 |
| LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 350 | 44 | 44 | 0 |
| LBR_ENST00000272163 | LBR | Q14739 | Delta(14)-sterol reductase LBR | chr1 | Not Cancer Driver | No | 1 | hippie | 95 | 130 | 15 | 15 | 5 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
| LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 222 | 25 | 25 | 1 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 2 | hippie, biogrid | 68 | 544 | 49 | 49 | 131 |
| LMNB1 | LMNB1 | P20700 | Lamin-B1 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 60 | 404 | 42 | 42 | 4 |
| LNPK_ENST00000272748 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 62 | 257 | 43 | 43 | 0 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 122 | 15 | 15 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
| LUC7L | LUC7L | Q9NQ29 | Putative RNA-binding protein Luc7-like 1 | chr16 | Not Cancer Driver | No | 3 | hippie, biogrid | 50 | 254 | 41 | 41 | 0 |
| LUC7L2 | LUC7L2 | Q9Y383 | Putative RNA-binding protein Luc7-like 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 262 | 45 | 45 | 0 |
| MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 12 | 1 | 1 | 0 |
| MAD2L1BP_ENST00000372171 | MAD2L1BP | Q15013 | MAD2L1-binding protein | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 26 | 55 | 7 | 7 | 0 |
| MAGED2 | MAGED2 | Q9UNF1 | Melanoma-associated antigen D2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 326 | 53 | 53 | 1 |
| MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
| MCF2L2 | MCF2L2 | Q86YR7 | Probable guanine nucleotide exchange factor MCF2L2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 222 | 306 | 61 | 61 | 0 |
| MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | Census, Compendium | Yes | 1 | hippie | 287 | 749 | 159 | 159 | 3 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 75 | 483 | 74 | 74 | 46 |
| MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | Not Cancer Driver | No | 1 | hippie | 76 | 446 | 42 | 42 | 0 |
| METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| MYO3B | MYO3B | Q8WXR4 | Myosin-IIIb | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 242 | 308 | 58 | 58 | 0 |
| MZF1 | MZF1 | P28698 | Myeloid zinc finger 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 468 | 49 | 49 | 0 |
| NBR1 | NBR1 | Q14596 | Next to BRCA1 gene 1 protein | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 560 | 51 | 51 | 0 |
| NET1 | NET1 | Q7Z628 | Neuroepithelial cell-transforming gene 1 protein | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 294 | 37 | 37 | 0 |
| NEUROG3 | NEUROG3 | Q9Y4Z2 | Neurogenin-3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 156 | 34 | 34 | 2 |
| NKX2-5 | NKX2-5 | P52952 | Homeobox protein Nkx-2.5 | chr5 | Not Cancer Driver | No | 1 | hippie | 48 | 181 | 22 | 22 | 55 |
| NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 62 | 252 | 24 | 24 | 0 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 284 | 10 | 0 | 0 | 14 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 221 | 19 | 19 | 1 |
| OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
| OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | hippie | 31 | 33 | 2 | 2 | 0 |
| OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 59 | 21 | 0 | 0 | 0 |
| P2RY2_ENST00000393596 | P2RY2 | P41231 | P2Y purinoceptor 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 60 | 13 | 13 | 0 |
| PAGE4_ENST00000376141 | PAGE4 | O60829 | P antigen family member 4 | chrX | Not Cancer Driver | No | 1 | hippie | 20 | 102 | 20 | 20 | 0 |
| PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
| PASK_ENST00000234040 | PASK | Q96RG2 | PAS domain-containing serine/threonine-protein kinase | chr2 | Not Cancer Driver | No | 1 | intact | 181 | 412 | 62 | 62 | 0 |
| PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
| PHLDA3 | PHLDA3 | Q9Y5J5 | Pleckstrin homology-like domain family A member 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 0 |
| PLD3_ENST00000409735 | PLD3 | Q8IV08 | 5'-3' exonuclease PLD3 | chr19 | Not Cancer Driver | No | 1 | biogrid | 70 | 62 | 7 | 7 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 38 | 27 | 6 | 6 | 0 |
| PPP1CB_ENST00000358506 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | Not Cancer Driver | No | 1 | hippie | 47 | 25 | 5 | 5 | 5 |
| PPP1CC_ENST00000335007 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | Not Cancer Driver | No | 1 | hippie | 26 | 23 | 4 | 4 | 0 |
| PRKCB_ENST00000321728 | PRKCB | P05771 | Protein kinase C beta type | chr16 | Census, Compendium | Yes | 1 | hippie | 205 | 148 | 40 | 40 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
| PRM1 | PRM1 | P04553 | Sperm protamine P1 | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 20 | 4 | 4 | 0 |
| PSMD3 | PSMD3 | O43242 | 26S proteasome non-ATPase regulatory subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 69 | 152 | 19 | 19 | 0 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | Census, Compendium | Yes | 1 | hippie | 243 | 382 | 67 | 67 | 18 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 140 | 25 | 25 | 0 |
| PXMP2 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| RAB3B | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 25 | 6 | 6 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 50 | 4 | 4 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 27 | 11 | 0 | 0 | 4 |
| RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 21 | 1 | 1 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 4 | 1 | 1 | 0 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
| REEP5 | REEP5 | Q00765 | Receptor expression-enhancing protein 5 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 0 | 0 | 0 | 0 |
| RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 38 | 69 | 9 | 9 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
| RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| RMDN3 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 196 | 17 | 17 | 0 |
| RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| RPL10_ENST00000369817 | RPL10 | P27635 | 60S ribosomal protein L10 | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 46 | 9 | 3 | 3 | 4 |
| RPL17_ENST00000579248 | RPL17 | P18621 | 60S ribosomal protein L17 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 97 | 14 | 14 | 0 |
| RPL28_ENST00000559463 | RPL28 | P46779 | 60S ribosomal protein L28 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 115 | 24 | 24 | 0 |
| RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
| RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
| RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | Not Cancer Driver | No | 1 | hippie | 38 | 150 | 25 | 25 | 0 |
| RRP1B | RRP1B | Q14684 | Ribosomal RNA processing protein 1 homolog B | chr21 | Not Cancer Driver | No | 1 | hippie | 74 | 513 | 48 | 48 | 0 |
| RSRP1 | RSRP1 | Q9BUV0 | Arginine/serine-rich protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 284 | 23 | 23 | 0 |
| S1PR4 | S1PR4 | O95977 | Sphingosine 1-phosphate receptor 4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 11 | 2 | 2 | 0 |
| SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
| SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
| SEC63 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 266 | 37 | 37 | 0 |
| SLC15A3 | SLC15A3 | Q8IY34 | Solute carrier family 15 member 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 43 | 1 | 1 | 0 |
| SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
| SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 96 | 2 | 2 | 4 |
| SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 97 | 11 | 11 | 0 |
| SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
| SRPK1 | SRPK1 | Q96SB4 | SRSF protein kinase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 73 | 329 | 32 | 32 | 0 |
| SRPK2_ENST00000489828 | SRPK2 | P78362 | SRSF protein kinase 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 78 | 343 | 46 | 46 | 0 |
| SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
| ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 64 | 5 | 5 | 0 |
| STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 387 | 45 | 45 | 13 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
| STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 164 | 14 | 14 | 0 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
| SYP | SYP | P08247 | Synaptophysin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 93 | 8 | 8 | 1 |
| TCF3 | TCF3 | P15923 | Transcription factor E2-alpha | chr19 | Census | Yes | 1 | hippie | 52 | 649 | 52 | 52 | 0 |
| TCTN2 | TCTN2 | Q96GX1 | Tectonic-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 75 | 23 | 2 | 2 | 0 |
| TCTN3 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | hippie | 45 | 71 | 8 | 8 | 1 |
| TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 399 | 46 | 46 | 0 |
| TIFAB | TIFAB | Q6ZNK6 | TRAF-interacting protein with FHA domain-containing protein B | chr5 | Not Cancer Driver | No | 1 | hippie | 32 | 26 | 7 | 7 | 0 |
| TLX2 | TLX2 | O43763 | T-cell leukemia homeobox protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 24 | 220 | 15 | 15 | 0 |
| TMEM17 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | hippie | 22 | 14 | 2 | 2 | 0 |
| TMEM216 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | hippie | 11 | 0 | 0 | 0 | 7 |
| TMEM41B_ENST00000611268 | TMEM41B | Q5BJD5 | Transmembrane protein 41B | chr11 | Not Cancer Driver | No | 1 | hippie | 19 | 47 | 3 | 3 | 0 |
| TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 412 | 52 | 52 | 0 |
| TNFRSF13B | TNFRSF13B | O14836 | Tumor necrosis factor receptor superfamily member 13B | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 108 | 25 | 25 | 0 |
| TNP2 | TNP2 | Q05952 | Nuclear transition protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 138 | 23 | 23 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | hippie | 59 | 52 | 11 | 11 | 8 |
| UBE2A | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | Compendium | Yes | 1 | hippie | 35 | 67 | 13 | 13 | 2 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
| USP51 | USP51 | Q70EK9 | Ubiquitin carboxyl-terminal hydrolase 51 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 100 | 246 | 34 | 34 | 0 |
| VSTM4 | VSTM4 | Q8IW00 | V-set and transmembrane domain-containing protein 4 | chr10 | Not Cancer Driver | No | 1 | hippie | 91 | 47 | 9 | 9 | 0 |
| WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 35 | 3 | 3 | 0 |
| WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 108 | 9 | 9 | 3 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 66 | 140 | 12 | 12 | 0 |
| YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 109 | 4 | 4 | 0 |
| YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 26 | 77 | 9 | 9 | 2 |
| YWHAH | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | Not Cancer Driver | No | 1 | hippie | 15 | 55 | 3 | 3 | 0 |
| ZBTB2 | ZBTB2 | Q8N680 | Zinc finger and BTB domain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 75 | 216 | 30 | 30 | 0 |
| ZC3H18_ENST00000301011 | ZC3H18 | Q86VM9 | Zinc finger CCCH domain-containing protein 18 | chr16 | Not Cancer Driver | No | 1 | hippie | 139 | 929 | 134 | 134 | 0 |
| ZNF385C | ZNF385C | Q66K41 | Zinc finger protein 385C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 260 | 15 | 15 | 0 |
| ZNF524_ENST00000301073 | ZNF524 | Q96C55 | Zinc finger protein 524 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 182 | 19 | 19 | 0 |
| ZNF579 | ZNF579 | Q8NAF0 | Zinc finger protein 579 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 28 | 447 | 22 | 22 | 0 |
| ZNF747 | ZNF747 | Q9BV97 | Zinc finger protein 747 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 192 | 15 | 15 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|