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LAMTOR2 ,LAMTOR2 ,Q9Y2Q5
  • Uniprot Accession= Q9Y2Q5
  • Ensembl Transcript= ENST00000368305.8
  • Uniprot Name= LAMTOR2
  • Name= Ragulator complex protein LAMTOR2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 57
  • Number of Interaction partner in hippie: 75
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 103 47 0 0 0
ABHD11 ABHD11 Q8NFV4 Protein ABHD11 chr7 Not Cancer Driver No 1 hippie, biogrid 38 73 6 6 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 26 24 3 3 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie, biogrid 144 767 104 104 2
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 39 11 0 0 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 intact, hippie 56 0 0 0 2
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 1 hippie 40 0 0 0 0
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 86 31 2 2 4
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 intact, hippie 63 49 4 4 1
BORCS6 BORCS6 Q96GS4 BLOC-1-related complex subunit 6 chr17 Not Cancer Driver No 3 intact, hippie 17 269 11 11 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie, biogrid 27 192 24 24 0
CDC16_ENST00000356221 CDC16 Q13042 Cell division cycle protein 16 homolog chr13 Not Cancer Driver No 1 hippie, biogrid 68 54 7 7 0
CDC23 CDC23 Q9UJX2 Cell division cycle protein 23 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 57 45 6 6 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 179 289 75 75 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CPNE8 CPNE8 Q86YQ8 Copine-8 chr12 Not Cancer Driver No 1 hippie, biogrid 102 40 12 12 0
CSNK1G3_ENST00000361991 CSNK1G3 Q9Y6M4 Casein kinase I isoform gamma-3 chr5 Not Cancer Driver No 1 hippie, biogrid 61 151 22 22 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
DYNLRB1 DYNLRB1 Q9NP97 Dynein light chain roadblock-type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 23 19 4 4 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 Not Cancer Driver No 1 hippie, biogrid 118 99 26 26 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie 298 396 70 70 3
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
FTH1_ENST00000620041 FTH1 P02794 Ferritin heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 20 57 7 7 0
HCCS HCCS P53701 Holocytochrome c-type synthase chrX Not Cancer Driver No 1 hippie, biogrid 48 117 25 25 1
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 103 674 82 82 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 47 93 10 10 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 8 intact, hippie, biogrid 13 96 7 7 0
LAMTOR3 LAMTOR3 Q9UHA4 Ragulator complex protein LAMTOR3 chr4 Not Cancer Driver No 3 hippie, biogrid 12 0 0 0 0
LAMTOR4 LAMTOR4 Q0VGL1 Ragulator complex protein LAMTOR4 chr7 Not Cancer Driver No 4 intact, hippie, biogrid 8 4 0 0 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 Not Cancer Driver No 4 intact, hippie, biogrid 10 17 0 0 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 99 175 15 15 10
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 19 12 2 2 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 1 hippie 94 96 24 24 6
MRPS21_ENST00000614145 MRPS21 P82921 28S ribosomal protein S21, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
MSRB2 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 17 65 6 6 0
MTHFD2 MTHFD2 P13995 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 39 39 3 3 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 Census, Compendium Yes 1 intact, hippie 379 296 37 37 18
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 57 8 0 0 2
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 81 40 3 3 2
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 34 26 3 3 2
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 66 57 9 9 3
NNT_ENST00000344920 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 129 47 6 6 11
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 Not Cancer Driver No 1 hippie, biogrid 65 54 8 8 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 23 76 13 13 0
PLEKHM1 PLEKHM1 Q9Y4G2 Pleckstrin homology domain-containing family M member 1 chr17 Not Cancer Driver No 1 intact 140 373 55 55 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie, biogrid 62 93 4 4 9
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 intact, hippie 18 21 1 1 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 Not Cancer Driver No 1 hippie, biogrid 60 302 44 44 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 Not Cancer Driver No 2 hippie, biogrid 30 0 0 0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX Not Cancer Driver No 4 intact, hippie, biogrid 67 37 5 5 0
RRAGC RRAGC Q9HB90 Ras-related GTP-binding protein C chr1 Compendium Yes 2 hippie, biogrid 29 61 1 1 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 Not Cancer Driver No 2 intact, hippie, biogrid 42 83 5 5 0
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 Census Yes 1 hippie, biogrid 37 17 3 3 23
SLC38A9 SLC38A9 Q8NBW4 Sodium-coupled neutral amino acid transporter 9 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 57 33 2 2 0
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 Not Cancer Driver No 1 biogrid 20 30 2 2 0
TMEM185A TMEM185A Q8NFB2 Transmembrane protein 185A chrX Not Cancer Driver No 1 hippie, biogrid 29 19 0 0 0
TMEM192 TMEM192 Q8IY95 Transmembrane protein 192 chr4 Not Cancer Driver No 1 hippie 31 5 1 1 0
TPP1 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 67 92 7 7 37
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 Not Cancer Driver No 1 hippie, biogrid 9 20 1 1 0
TUBD1_ENST00000592426 TUBD1 Q9UJT1 Tubulin delta chain chr17 Not Cancer Driver No 1 hippie, biogrid 54 3 0 0 0
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 Not Cancer Driver No 1 hippie, biogrid 21 44 6 6 0
UQCRC1 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 57 55 6 6 2
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 65 62 10 10 0