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LAD1 ,LAD1 ,O00515
  • Number of Interaction partner in intact: 4
  • Number of Interaction partner in biogrid: 23
  • Number of Interaction partner in hippie: 38
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACOX1_ENST00000301608 ACOX1 Q15067 Peroxisomal acyl-coenzyme A oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 71 63 11 11 7
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 Not Cancer Driver No 1 hippie, biogrid 120 500 56 56 6
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARMC8_ENST00000469044 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie, biogrid 71 7 0 0 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
COL17A1 COL17A1 Q9UMD9 Collagen alpha-1(XVII) chain chr10 Not Cancer Driver No 1 hippie 196 1275 164 164 5
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 90 92 11 11 1
FEM1A FEM1A Q9BSK4 Protein fem-1 homolog A chr19 Not Cancer Driver No 1 hippie, biogrid 68 162 22 22 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie, biogrid 416 1456 214 214 28
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie, biogrid 362 1183 170 170 19
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie, biogrid 546 1442 288 288 7
GID4 GID4 Q8IVV7 Glucose-induced degradation protein 4 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 24 143 4 4 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 56 35 5 5 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HECTD3 HECTD3 Q5T447 E3 ubiquitin-protein ligase HECTD3 chr1 Not Cancer Driver No 1 hippie, biogrid 88 55 5 5 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
KLHL18 KLHL18 O94889 Kelch-like protein 18 chr3 Not Cancer Driver No 1 hippie, biogrid 82 31 10 10 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 intact, hippie 101 128 22 22 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 Not Cancer Driver No 1 hippie, biogrid 54 176 19 19 0
MKLN1 MKLN1 Q9UL63 Muskelin chr7 Not Cancer Driver No 1 hippie, biogrid 85 91 13 13 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie, biogrid 48 111 17 17 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie, biogrid 101 76 22 22 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
RMND5A RMND5A Q9H871 E3 ubiquitin-protein transferase RMND5A chr2 Not Cancer Driver No 1 hippie, biogrid 46 0 0 0 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie, biogrid 27 100 5 5 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 Not Cancer Driver No 1 hippie 47 25 2 2 0
TIPARP TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 Not Cancer Driver No 1 hippie, biogrid 65 200 20 20 0
TUBB2B TUBB2B Q9BVA1 Tubulin beta-2B chain chr6 Not Cancer Driver No 1 hippie, biogrid 43 68 10 10 10
WDR26 WDR26 Q9H7D7 WD repeat-containing protein 26 chr1 Not Cancer Driver No 1 hippie, biogrid 71 187 9 9 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 Not Cancer Driver No 1 hippie, biogrid 73 324 45 45 0
ZMYND19 ZMYND19 Q96E35 Zinc finger MYND domain-containing protein 19 chr9 Not Cancer Driver No 1 hippie, biogrid 21 20 4 4 0
ZZEF1 ZZEF1 O43149 Zinc finger ZZ-type and EF-hand domain-containing protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 292 580 69 69 0