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KIF2C ,KIF2C ,Q99661
  • Uniprot Accession= Q99661
  • Ensembl Transcript= ENST00000372224.8
  • Uniprot Name= KIF2C
  • Name= Kinesin-like protein KIF2C
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 9
  • Number of Interaction partner in biogrid: 55
  • Number of Interaction partner in hippie: 129
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR3B ACTR3B Q9P1U1 Actin-related protein 3B chr7 Not Cancer Driver No 1 hippie, biogrid 55 5 0 0 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 hippie 86 129 13 13 0
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 21 30 1 1 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 Not Cancer Driver No 1 hippie 70 54 1 1 0
ANKS3_ENST00000614075 ANKS3 Q6ZW76 Ankyrin repeat and SAM domain-containing protein 3 chr16 Not Cancer Driver No 1 hippie, biogrid 58 292 28 28 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ATP6V0C ATP6V0C P27449 V-type proton ATPase 16 kDa proteolipid subunit c chr16 Not Cancer Driver No 1 hippie, biogrid 19 1 0 0 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 36 178 21 21 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCCIP_ENST00000278100 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 Not Cancer Driver No 1 hippie 35 99 16 16 0
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 Not Cancer Driver No 2 hippie, biogrid 119 154 25 25 3
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRPF1_ENST00000457855 BRPF1 P55201 Peregrin chr3 Not Cancer Driver No 1 hippie 148 753 95 95 2
CALML3 CALML3 P27482 Calmodulin-like protein 3 chr10 Not Cancer Driver No 1 hippie, biogrid 34 105 28 28 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 hippie 100 618 77 77 0
CDCA8_ENST00000327331 CDCA8 Q53HL2 Borealin chr1 Not Cancer Driver No 1 hippie 23 170 13 13 0
CENPB CENPB P07199 Major centromere autoantigen B chr20 Not Cancer Driver No 1 hippie 64 374 39 39 0
CENPH CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie 28 85 7 7 0
CEP170 CEP170 Q5SW79 Centrosomal protein of 170 kDa chr1 Not Cancer Driver No 1 hippie 264 1429 246 246 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 20 19 0 0 4
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 2 hippie, biogrid 172 817 111 111 11
DDHD1 DDHD1 Q8NEL9 Phospholipase DDHD1 chr14 Not Cancer Driver No 1 hippie, biogrid 120 393 40 40 0
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 Not Cancer Driver No 3 hippie, biogrid 166 257 45 45 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 21 4 1 1 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 86 208 30 30 10
ESPL1 ESPL1 Q14674 Separin chr12 Not Cancer Driver No 1 hippie 211 380 39 39 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FADD FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 26 45 10 10 1
FBXO11 FBXO11 Q86XK2 F-box only protein 11 chr2 Census, Compendium Yes 1 hippie, biogrid 113 242 22 22 8
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 48 113 13 13 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 56 35 5 5 0
GTF2F1 GTF2F1 P35269 General transcription factor IIF subunit 1 chr19 Not Cancer Driver No 1 hippie 63 426 48 48 0
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 Not Cancer Driver No 1 hippie, biogrid 32 413 32 32 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie, biogrid 44 219 32 32 2
HORMAD2 HORMAD2 Q8N7B1 HORMA domain-containing protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 28 29 3 3 0
HSPA14 HSPA14 Q0VDF9 Heat shock 70 kDa protein 14 chr10 Not Cancer Driver No 1 hippie, biogrid 52 22 0 0 0
INSYN1 INSYN1 Q2T9L4 Inhibitory synaptic factor 1 chr15 Not Cancer Driver No 1 hippie 44 253 41 41 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF18B KIF18B Q86Y91 Kinesin-like protein KIF18B chr17 Not Cancer Driver No 1 hippie 100 590 69 69 0
KIF2A_ENST00000401507 KIF2A O00139 Kinesin-like protein KIF2A chr5 Not Cancer Driver No 2 hippie, biogrid 74 336 37 37 2
KIF2B KIF2B Q8N4N8 Kinesin-like protein KIF2B chr17 Not Cancer Driver No 2 intact, hippie, biogrid 314 189 116 116 0
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 Not Cancer Driver No 1 hippie 110 337 63 63 0
KLHL40 KLHL40 Q2TBA0 Kelch-like protein 40 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 108 44 8 8 13
KRT38 KRT38 O76015 Keratin, type I cuticular Ha8 chr17 Not Cancer Driver No 1 hippie, biogrid 89 52 15 15 0
KRT79 KRT79 Q5XKE5 Keratin, type II cytoskeletal 79 chr12 Not Cancer Driver No 1 hippie 94 230 43 43 0
KXD1_ENST00000222307 KXD1 Q9BQD3 KxDL motif-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 24 104 17 17 0
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 Census Yes 1 hippie, biogrid 67 408 63 63 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 2 hippie, biogrid 26 109 11 11 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 2 hippie, biogrid 37 120 16 16 0
MBD1_ENST00000591416 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 Not Cancer Driver No 1 hippie 115 322 49 49 0
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 12 46 3 3 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRFAP1L1 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
MRPL52 MRPL52 Q86TS9 39S ribosomal protein L52, mitochondrial chr14 Not Cancer Driver No 1 hippie 11 75 7 7 0
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 Not Cancer Driver No 1 hippie 117 160 15 15 0
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 hippie 370 1208 329 329 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie, biogrid 268 1237 176 176 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 Not Cancer Driver No 1 hippie 32 202 16 16 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie, biogrid 194 722 162 162 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PAPLN_ENST00000644200 PAPLN O95428 Papilin chr14 Not Cancer Driver No 2 intact, hippie, biogrid 175 572 74 74 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 120 461 39 39 0
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 40 200 24 24 0
PCGF5 PCGF5 Q86SE9 Polycomb group RING finger protein 5 chr10 Not Cancer Driver No 1 hippie 31 52 5 5 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 Not Cancer Driver No 1 hippie 161 495 75 75 3
PRPF38B PRPF38B Q5VTL8 Pre-mRNA-splicing factor 38B chr1 Not Cancer Driver No 1 hippie, biogrid 70 387 52 52 0
PRRC2A_ENST00000376007 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 1 hippie, biogrid 253 2119 249 249 0
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 Not Cancer Driver No 1 hippie 139 214 28 28 0
RBM26_ENST00000438737 RBM26 Q5T8P6 RNA-binding protein 26 chr13 Not Cancer Driver No 1 hippie, biogrid 117 834 100 100 0
RBMX2 RBMX2 Q9Y388 RNA-binding motif protein, X-linked 2 chrX Not Cancer Driver No 1 hippie, biogrid 49 217 36 36 0
RBMXL1 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 Not Cancer Driver No 1 hippie, biogrid 77 371 75 75 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 49 151 19 19 2
RELL2 RELL2 Q8NC24 RELT-like protein 2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 39 259 37 37 0
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 Census Yes 1 hippie 57 96 17 17 2
RPL7 RPL7 P18124 60S ribosomal protein L7 chr8 Not Cancer Driver No 1 hippie 24 40 4 4 0
RPL9 RPL9 Q53Z07 60S ribosomal protein L9 chr4 Not Cancer Driver No 1 hippie 30 3 0 0 0
RPS25 RPS25 P62851 40S ribosomal protein S25 chr11 Not Cancer Driver No 1 hippie 16 60 8 8 0
RRP12 RRP12 Q5JTH9 RRP12-like protein chr10 Not Cancer Driver No 1 hippie 155 336 56 56 0
RRP36 RRP36 Q96EU6 Ribosomal RNA processing protein 36 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 28 215 24 24 0
SAR1B SAR1B Q9Y6B6 GTP-binding protein SAR1b chr5 Not Cancer Driver No 1 hippie, biogrid 17 4 0 0 5
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 Not Cancer Driver No 1 hippie 48 187 30 30 0
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 Not Cancer Driver No 1 hippie, biogrid 101 442 98 98 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 Not Cancer Driver No 1 hippie, biogrid 147 561 145 145 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 2 intact, hippie 31 131 17 17 0
SGMS2 SGMS2 Q8NHU3 Phosphatidylcholine:ceramide cholinephosphotransferase 2 chr4 Not Cancer Driver No 1 hippie 37 49 7 7 0
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 Not Cancer Driver No 1 hippie 57 360 39 39 1
SGO2 SGO2 Q562F6 Shugoshin 2 chr2 Not Cancer Driver No 1 hippie 164 1025 134 134 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 175 539 55 55 0
SNRNP27 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 1 hippie, biogrid 20 155 20 20 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SRGAP3 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 1 hippie 195 549 97 97 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 Not Cancer Driver No 1 hippie, biogrid 70 241 32 32 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 hippie, biogrid 70 231 30 30 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 hippie 42 302 26 26 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 Not Cancer Driver No 1 hippie 51 1 0 0 0
TCP10L TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 32 213 32 32 0
TEX10 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 Not Cancer Driver No 1 hippie 115 103 12 12 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 30 5 5 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie, biogrid 198 1350 151 151 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 2 intact, hippie, biogrid 58 111 15 15 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 hippie, biogrid 48 229 28 28 0
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 Not Cancer Driver No 1 hippie, biogrid 106 89 21 21 1
TYW3 TYW3 Q6IPR3 tRNA wybutosine-synthesizing protein 3 homolog chr1 Not Cancer Driver No 2 intact, hippie, biogrid 35 57 12 12 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie, biogrid 35 67 13 13 2
UTP11 UTP11 Q9Y3A2 Probable U3 small nucleolar RNA-associated protein 11 chr1 Not Cancer Driver No 1 hippie 35 104 11 11 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 hippie 188 110 28 28 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR18 WDR18 Q9BV38 WD repeat-containing protein 18 chr19 Not Cancer Driver No 1 hippie 38 60 2 2 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 Not Cancer Driver No 1 hippie 181 792 100 100 5
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 38 26 3 3 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
ZNF566_ENST00000434377 ZNF566 Q969W8 Zinc finger protein 566 chr19 Not Cancer Driver No 1 hippie 78 53 9 9 0
ZNF668_ENST00000535577 ZNF668 Q96K58 Zinc finger protein 668 chr16 Not Cancer Driver No 1 hippie 100 314 54 54 0