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KIAA2013_ENST00000616327 ,KIAA2013 ,Q8IYS2
  • Number of Interaction partner in intact: 30
  • Number of Interaction partner in biogrid: 75
  • Number of Interaction partner in hippie: 102
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACKR2 ACKR2 O00590 Atypical chemokine receptor 2 chr3 Not Cancer Driver No 1 hippie, biogrid 70 25 6 6 0
ADGRE5 ADGRE5 P48960 Adhesion G protein-coupled receptor E5 chr19 Not Cancer Driver No 1 hippie 115 109 10 10 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 Not Cancer Driver No 1 hippie 130 40 8 8 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 46 85 7 7 0
ATP1B3 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 Not Cancer Driver No 1 hippie, biogrid 36 6 1 1 0
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 2 hippie, biogrid 67 0 0 0 4
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 3 intact, hippie, biogrid 56 0 0 0 2
ATP6V0A1_ENST00000343619 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 Not Cancer Driver No 2 hippie, biogrid 98 85 14 14 0
ATP6V0A2 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 Not Cancer Driver No 2 hippie, biogrid 88 36 6 6 0
ATP6V0C ATP6V0C P27449 V-type proton ATPase 16 kDa proteolipid subunit c chr16 Not Cancer Driver No 1 intact, hippie, biogrid 19 1 0 0 0
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 2 hippie, biogrid 40 0 0 0 0
ATP6V0D2 ATP6V0D2 Q8N8Y2 V-type proton ATPase subunit d 2 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 81 0 0 0 0
ATP6V1F_ENST00000249289 ATP6V1F Q16864 V-type proton ATPase subunit F chr7 Not Cancer Driver No 1 hippie, biogrid 14 12 1 1 0
B3GAT3 B3GAT3 O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 chr11 Not Cancer Driver No 1 hippie, biogrid 42 139 17 17 2
BSCL2_ENST00000421906 BSCL2 Q96G97 Seipin chr11 Not Cancer Driver No 2 hippie, biogrid 55 125 15 15 5
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 71 0 0 0 0
CAMKK1_ENST00000348335 CAMKK1 Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 chr17 Not Cancer Driver No 1 intact, hippie 82 246 32 32 0
CCDC115 CCDC115 Q96NT0 Coiled-coil domain-containing protein 115 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 21 89 8 8 2
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 Not Cancer Driver No 1 hippie, biogrid 56 13 2 2 0
CEACAM21 CEACAM21 Q3KPI0 Carcinoembryonic antigen-related cell adhesion molecule 21 chr19 Not Cancer Driver No 1 hippie, biogrid 51 73 14 14 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 Not Cancer Driver No 1 hippie, biogrid 144 186 33 33 2
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 Not Cancer Driver No 2 intact, hippie, biogrid 110 71 19 19 7
CLDND1_ENST00000510545 CLDND1 Q9NY35 Claudin domain-containing protein 1 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 32 0 0 0 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 Not Cancer Driver No 1 hippie, biogrid 34 57 8 8 0
CLEC2B CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 Not Cancer Driver No 1 hippie, biogrid 107 24 13 13 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 Not Cancer Driver No 1 intact, hippie 57 21 4 4 0
COMTD1 COMTD1 Q86VU5 Catechol O-methyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 11 23 0 0 0
CRELD1_ENST00000383811 CRELD1 Q96HD1 Protein disulfide isomerase CRELD1 chr3 Not Cancer Driver No 1 hippie, biogrid 45 44 7 7 4
CSGALNACT2 CSGALNACT2 Q8N6G5 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 99 109 23 23 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 Not Cancer Driver No 1 hippie, biogrid 55 7 2 2 0
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR34_ENST00000378138 GPR34 Q9UPC5 Probable G-protein coupled receptor 34 chrX Not Cancer Driver No 1 hippie, biogrid 57 9 0 0 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 Not Cancer Driver No 1 hippie, biogrid 57 0 0 0 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 Not Cancer Driver No 1 hippie, biogrid 82 75 19 19 0
GPRC5C_ENST00000392629 GPRC5C Q9NQ84 G-protein coupled receptor family C group 5 member C chr17 Not Cancer Driver No 1 hippie, biogrid 77 58 15 15 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 Not Cancer Driver No 1 hippie, biogrid 48 12 1 1 0
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 Not Cancer Driver No 1 hippie 31 202 11 11 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 1 hippie, biogrid 67 304 25 25 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie, biogrid 77 504 45 45 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 119 141 28 28 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 intact, hippie, biogrid 73 282 35 35 0
HTR3C HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C chr3 Not Cancer Driver No 1 hippie, biogrid 82 35 7 7 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 Not Cancer Driver No 1 intact, hippie 27 112 17 17 0
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 65 21 4 4 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 Not Cancer Driver No 1 hippie, biogrid 37 0 0 0 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 intact, hippie 65 121 18 18 0
KRTCAP3 KRTCAP3 Q53RY4 Keratinocyte-associated protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 19 37 4 4 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 Not Cancer Driver No 1 hippie, biogrid 79 21 6 6 0
LPAR2_ENST00000586703 LPAR2 Q9HBW0 Lysophosphatidic acid receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 47 2 0 0 0
LY86 LY86 O95711 Lymphocyte antigen 86 chr6 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
NIPAL1 NIPAL1 Q6NVV3 Magnesium transporter NIPA3 chr4 Not Cancer Driver No 1 hippie, biogrid 51 2 0 0 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 Not Cancer Driver No 1 intact, hippie 339 64 33 33 37
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 Census, Compendium Yes 2 hippie, biogrid 159 528 132 132 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 57 21 2 2 3
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 Not Cancer Driver No 1 hippie, biogrid 67 60 13 13 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX Census, Compendium Yes 1 hippie, biogrid 126 23 5 5 0
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 1 intact, hippie 50 166 23 23 0
PCDHB3 PCDHB3 Q9Y5E6 Protocadherin beta-3 chr5 Not Cancer Driver No 1 hippie, biogrid 258 119 30 30 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie, biogrid 50 49 3 3 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 Not Cancer Driver No 1 hippie, biogrid 42 0 0 0 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 Census, Compendium Yes 1 hippie, biogrid 243 382 67 67 18
RAB32 RAB32 Q13637 Ras-related protein Rab-32 chr6 Not Cancer Driver No 1 intact, hippie 18 40 2 2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 intact, hippie 66 2 1 1 6
RALA RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 34 34 3 3 5
RBM45_ENST00000616198 RBM45 Q8IUH3 RNA-binding protein 45 chr2 Not Cancer Driver No 1 intact, hippie 56 105 20 20 0
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 Not Cancer Driver No 1 hippie 76 68 4 4 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 86 29 6 6 0
S1PR4 S1PR4 O95977 Sphingosine 1-phosphate receptor 4 chr19 Not Cancer Driver No 1 hippie, biogrid 68 11 2 2 0
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 1 hippie, biogrid 63 16 5 5 3
SFTPC SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 1 hippie, biogrid 21 19 2 2 5
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 intact, hippie 110 440 72 72 0
SKA3 SKA3 Q8IX90 Spindle and kinetochore-associated protein 3 chr13 Not Cancer Driver No 1 intact, hippie 56 230 32 32 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 68 99 17 17 0
SRPRA SRPRA P08240 Signal recognition particle receptor subunit alpha chr11 Not Cancer Driver No 1 intact, hippie 95 232 40 40 0
ST8SIA5_ENST00000315087 ST8SIA5 O15466 Alpha-2,8-sialyltransferase 8E chr18 Not Cancer Driver No 1 hippie, biogrid 98 0 0 0 0
STARD3NL STARD3NL O95772 STARD3 N-terminal-like protein chr7 Not Cancer Driver No 1 hippie, biogrid 34 32 2 2 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 Compendium Yes 1 hippie, biogrid 68 102 6 6 5
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 Not Cancer Driver No 2 hippie, biogrid 16 3 0 0 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 Not Cancer Driver No 1 hippie, biogrid 26 9 1 1 0
TMEM185A TMEM185A Q8NFB2 Transmembrane protein 185A chrX Not Cancer Driver No 1 hippie, biogrid 29 19 0 0 0
TMEM199 TMEM199 Q8N511 Transmembrane protein 199 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 24 54 5 5 3
TMEM60 TMEM60 Q9H2L4 Transmembrane protein 60 chr7 Not Cancer Driver No 1 intact, hippie 13 0 0 0 0
TMEM63A TMEM63A O94886 CSC1-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 87 36 1 1 3
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 1 intact, hippie 284 1830 265 265 0
TSPAN15 TSPAN15 O95858 Tetraspanin-15 chr10 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
TSPAN17_ENST00000515708 TSPAN17 Q96FV3 Tetraspanin-17 chr5 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
TTYH3 TTYH3 Q9C0H2 Protein tweety homolog 3 chr7 Not Cancer Driver No 1 hippie, biogrid 48 91 14 14 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 intact, hippie 170 215 45 45 0
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 41 10 2 2 0
VIPR2 VIPR2 P41587 Vasoactive intestinal polypeptide receptor 2 chr7 Not Cancer Driver No 1 hippie, biogrid 74 0 0 0 0
VMA21 VMA21 Q3ZAQ7 Vacuolar ATPase assembly integral membrane protein VMA21 chrX Not Cancer Driver No 2 intact, hippie, biogrid 18 7 1 1 0
ZACN ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 Not Cancer Driver No 3 hippie, biogrid 46 48 6 6 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 67 23 0 0 3
ZNF687 ZNF687 Q8N1G0 Zinc finger protein 687 chr1 Not Cancer Driver No 1 intact, hippie 138 776 83 83 1
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 1 hippie 115 99 26 26 0