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KIAA1522_ENST00000373480 ,KIAA1522 ,Q9P206
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 62
  • Number of Interaction partner in hippie: 91
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 3 intact, hippie, biogrid 55 360 39 39 0
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 56 361 38 38 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 1 hippie, biogrid 104 68 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
ANAPC15_ENST00000538393 ANAPC15 P60006 Anaphase-promoting complex subunit 15 chr11 Not Cancer Driver No 1 hippie, biogrid 15 117 14 14 0
ANKRD50 ANKRD50 Q9ULJ7 Ankyrin repeat domain-containing protein 50 chr4 Not Cancer Driver No 1 hippie, biogrid 205 432 71 71 0
ARHGAP12 ARHGAP12 Q8IWW6 Rho GTPase-activating protein 12 chr10 Not Cancer Driver No 1 hippie, biogrid 97 497 56 56 0
ARHGAP26 ARHGAP26 Q9UNA1 Rho GTPase-activating protein 26 chr5 Census Yes 1 hippie, biogrid 99 259 26 26 1
ASAP1 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 183 584 108 108 0
ASAP2 ASAP2 O43150 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 141 453 63 63 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 85 330 52 52 0
BAIAP2L1 BAIAP2L1 Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 76 293 42 42 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 Not Cancer Driver No 1 hippie 86 142 26 26 5
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 Not Cancer Driver No 1 hippie, biogrid 7 14 1 1 0
C11orf52 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 15 108 12 12 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 6 6 2
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CCDC61 CCDC61 Q9Y6R9 Centrosomal protein CCDC61 chr19 Not Cancer Driver No 1 intact, hippie 44 348 32 32 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie, biogrid 24 114 21 21 1
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 Not Cancer Driver No 1 hippie 121 624 87 87 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 46 96 0 0 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 211 86 11 11 3
DHPS DHPS P49366 Deoxyhypusine synthase chr19 Not Cancer Driver No 1 hippie, biogrid 52 69 4 4 1
ENAH ENAH Q8N8S7 Protein enabled homolog chr1 Not Cancer Driver No 1 hippie, biogrid 65 514 61 61 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
EVL_ENST00000402714 EVL Q9UI08 Ena/VASP-like protein chr14 Not Cancer Driver No 1 hippie, biogrid 42 335 37 37 0
FAAP100 FAAP100 Q0VG06 Fanconi anemia core complex-associated protein 100 chr17 Not Cancer Driver No 1 hippie 93 207 31 31 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 intact 152 230 43 43 74
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
GNL2 GNL2 Q13823 Nucleolar GTP-binding protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 87 446 51 51 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
ITIH6 ITIH6 Q6UXX5 Inter-alpha-trypsin inhibitor heavy chain H6 chrX Not Cancer Driver No 1 hippie, biogrid 257 528 119 119 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KHDRBS2 KHDRBS2 Q5VWX1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 168 268 140 140 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 86 94 13 13 1
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
MAK16 MAK16 Q9BXY0 Protein MAK16 homolog chr8 Not Cancer Driver No 1 hippie, biogrid 41 130 19 19 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MMGT1 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 1 intact, hippie 24 17 4 4 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 48 111 17 17 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 3 hippie, biogrid 89 88 19 19 0
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 129 44 3 3 0
NHS NHS Q6T4R5 Nance-Horan syndrome protein chrX Not Cancer Driver No 1 hippie, biogrid 277 1515 254 254 0
NHSL1 NHSL1 Q5SYE7 NHS-like protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 60 1535 58 58 0
NIP7 NIP7 Q9Y221 60S ribosome subunit biogenesis protein NIP7 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 16 1 0 0 0
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 39 49 7 7 28
NPM3 NPM3 O75607 Nucleoplasmin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 23 78 11 11 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie 284 10 0 0 14
NSA2 NSA2 O95478 Ribosome biogenesis protein NSA2 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 29 134 17 17 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 30 22 3 3 1
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie, biogrid 158 186 21 21 0
POLR1A POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 intact, hippie 208 361 64 64 2
PPAN PPAN Q9NQ55 Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 hippie 65 257 42 42 0
PPAN-P2RY11_ENST00000428358 PPAN-P2RY11 Q9NQ55-3 Isoform 3 of Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 biogrid 81 275 52 52 0
PPP1R13L_ENST00000360957 PPP1R13L Q8WUF5 RelA-associated inhibitor chr19 Not Cancer Driver No 1 hippie, biogrid 117 657 90 90 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 1 hippie, biogrid 50 65 9 9 0
PUM3 PUM3 Q15397 Pumilio homolog 3 chr9 Not Cancer Driver No 1 hippie 74 170 19 19 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 hippie, biogrid 21 107 11 11 0
RRS1 RRS1 Q15050 Ribosome biogenesis regulatory protein homolog chr8 Not Cancer Driver No 1 hippie, biogrid 23 315 18 18 0
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie, biogrid 35 221 26 26 2
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 Not Cancer Driver No 1 intact, hippie 40 39 7 7 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 102 530 82 82 0
SLMAP SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 Not Cancer Driver No 2 intact, hippie, biogrid 77 464 38 38 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SORBS3 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 hippie, biogrid 62 577 56 56 0
STRN STRN O43815 Striatin chr2 Census, Compendium Yes 1 hippie, biogrid 97 348 43 43 0
TACC3 TACC3 Q9Y6A5 Transforming acidic coiled-coil-containing protein 3 chr4 Not Cancer Driver No 1 hippie, biogrid 98 707 81 81 0
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 Not Cancer Driver No 1 intact, hippie 88 173 25 25 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 hippie, biogrid 129 716 68 68 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 intact 170 215 45 45 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 3 intact, hippie, biogrid 39 335 34 34 0
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 Not Cancer Driver No 1 hippie, biogrid 63 445 49 49 0
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 61 400 43 43 0
WASF3 WASF3 Q9UPY6 Wiskott-Aldrich syndrome protein family member 3 chr13 Not Cancer Driver No 1 hippie, biogrid 108 386 84 84 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, hippie, biogrid 26 77 9 9 2