Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | Census, Compendium | Yes | 3 | intact, hippie, biogrid | 55 | 360 | 39 | 39 | 0 |
ABI2_ENST00000261018 | ABI2 | Q9NYB9 | Abl interactor 2 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 56 | 361 | 38 | 38 | 0 |
ACE2 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 68 | 5 | 5 | 0 |
ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 43 | 5 | 5 | 5 |
AFDN_ENST00000447894 | AFDN | P55196 | Afadin | chr6 | Census | Yes | 1 | hippie | 248 | 1247 | 180 | 180 | 0 |
ANAPC15_ENST00000538393 | ANAPC15 | P60006 | Anaphase-promoting complex subunit 15 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 117 | 14 | 14 | 0 |
ANKRD50 | ANKRD50 | Q9ULJ7 | Ankyrin repeat domain-containing protein 50 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 205 | 432 | 71 | 71 | 0 |
ARHGAP12 | ARHGAP12 | Q8IWW6 | Rho GTPase-activating protein 12 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 497 | 56 | 56 | 0 |
ARHGAP26 | ARHGAP26 | Q9UNA1 | Rho GTPase-activating protein 26 | chr5 | Census | Yes | 1 | hippie, biogrid | 99 | 259 | 26 | 26 | 1 |
ASAP1 | ASAP1 | Q9ULH1 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 183 | 584 | 108 | 108 | 0 |
ASAP2 | ASAP2 | O43150 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 141 | 453 | 63 | 63 | 0 |
BAIAP2 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 85 | 330 | 52 | 52 | 0 |
BAIAP2L1 | BAIAP2L1 | Q9UHR4 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 293 | 42 | 42 | 0 |
BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | Not Cancer Driver | No | 1 | hippie | 86 | 142 | 26 | 26 | 5 |
BRK1 | BRK1 | Q8WUW1 | Protein BRICK1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 14 | 1 | 1 | 0 |
C11orf52 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 108 | 12 | 12 | 0 |
C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 103 | 6 | 6 | 2 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 2 | 0 | 0 | 0 |
CCDC61 | CCDC61 | Q9Y6R9 | Centrosomal protein CCDC61 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 44 | 348 | 32 | 32 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 287 | 145 | 18 | 18 | 151 |
CHCHD2 | CHCHD2 | Q9Y6H1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 114 | 21 | 21 | 1 |
CTDP1 | CTDP1 | Q9Y5B0 | RNA polymerase II subunit A C-terminal domain phosphatase | chr18 | Not Cancer Driver | No | 1 | hippie | 121 | 624 | 87 | 87 | 0 |
CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 96 | 0 | 0 | 0 |
CYFIP2 | CYFIP2 | Q96F07 | Cytoplasmic FMR1-interacting protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 211 | 86 | 11 | 11 | 3 |
DHPS | DHPS | P49366 | Deoxyhypusine synthase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 69 | 4 | 4 | 1 |
ENAH | ENAH | Q8N8S7 | Protein enabled homolog | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 514 | 61 | 61 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
EVL_ENST00000402714 | EVL | Q9UI08 | Ena/VASP-like protein | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 335 | 37 | 37 | 0 |
FAAP100 | FAAP100 | Q0VG06 | Fanconi anemia core complex-associated protein 100 | chr17 | Not Cancer Driver | No | 1 | hippie | 93 | 207 | 31 | 31 | 0 |
FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | Census, Compendium | Yes | 1 | intact | 152 | 230 | 43 | 43 | 74 |
FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | Census, Compendium | Yes | 1 | intact | 113 | 162 | 28 | 28 | 0 |
FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 122 | 15 | 15 | 0 |
GNL2 | GNL2 | Q13823 | Nucleolar GTP-binding protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 446 | 51 | 51 | 0 |
HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
ITIH6 | ITIH6 | Q6UXX5 | Inter-alpha-trypsin inhibitor heavy chain H6 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 257 | 528 | 119 | 119 | 0 |
KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
KHDRBS2 | KHDRBS2 | Q5VWX1 | KH domain-containing, RNA-binding, signal transduction-associated protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 168 | 268 | 140 | 140 | 0 |
KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | intact, hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 93 | 10 | 10 | 0 |
LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | Census | Yes | 1 | hippie, biogrid | 86 | 94 | 13 | 13 | 1 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie, biogrid | 95 | 84 | 12 | 12 | 0 |
MAK16 | MAK16 | Q9BXY0 | Protein MAK16 homolog | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 130 | 19 | 19 | 0 |
MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
MMGT1 | MMGT1 | Q8N4V1 | ER membrane protein complex subunit 5 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 24 | 17 | 4 | 4 | 0 |
NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 48 | 111 | 17 | 17 | 0 |
NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 89 | 88 | 19 | 19 | 0 |
NCKAP1_ENST00000361354 | NCKAP1 | Q9Y2A7 | Nck-associated protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 129 | 44 | 3 | 3 | 0 |
NHS | NHS | Q6T4R5 | Nance-Horan syndrome protein | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 277 | 1515 | 254 | 254 | 0 |
NHSL1 | NHSL1 | Q5SYE7 | NHS-like protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 1535 | 58 | 58 | 0 |
NIP7 | NIP7 | Q9Y221 | 60S ribosome subunit biogenesis protein NIP7 homolog | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 1 | 0 | 0 | 0 |
NMNAT1 | NMNAT1 | Q9HAN9 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 49 | 7 | 7 | 28 |
NPM3 | NPM3 | O75607 | Nucleoplasmin-3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 78 | 11 | 11 | 0 |
NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie | 284 | 10 | 0 | 0 | 14 |
NSA2 | NSA2 | O95478 | Ribosome biogenesis protein NSA2 homolog | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 134 | 17 | 17 | 0 |
OCLN | OCLN | Q16625 | Occludin | chr5 | Not Cancer Driver | No | 1 | biogrid | 54 | 244 | 21 | 21 | 1 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 22 | 3 | 3 | 1 |
PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | Census, Compendium | Yes | 1 | hippie, biogrid | 158 | 186 | 21 | 21 | 0 |
POLR1A | POLR1A | O95602 | DNA-directed RNA polymerase I subunit RPA1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 208 | 361 | 64 | 64 | 2 |
PPAN | PPAN | Q9NQ55 | Suppressor of SWI4 1 homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 65 | 257 | 42 | 42 | 0 |
PPAN-P2RY11_ENST00000428358 | PPAN-P2RY11 | Q9NQ55-3 | Isoform 3 of Suppressor of SWI4 1 homolog | chr19 | Not Cancer Driver | No | 1 | biogrid | 81 | 275 | 52 | 52 | 0 |
PPP1R13L_ENST00000360957 | PPP1R13L | Q8WUF5 | RelA-associated inhibitor | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 657 | 90 | 90 | 0 |
PPP2R2D | PPP2R2D | Q66LE6 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 65 | 9 | 9 | 0 |
PUM3 | PUM3 | Q15397 | Pumilio homolog 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 74 | 170 | 19 | 19 | 0 |
RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
RPL26L1 | RPL26L1 | Q9UNX3 | 60S ribosomal protein L26-like 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 107 | 11 | 11 | 0 |
RRS1 | RRS1 | Q15050 | Ribosome biogenesis regulatory protein homolog | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 315 | 18 | 18 | 0 |
SET | SET | Q01105 | Protein SET | chr9 | Census, Compendium | Yes | 1 | hippie, biogrid | 35 | 221 | 26 | 26 | 2 |
SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 39 | 7 | 7 | 0 |
SH3KBP1 | SH3KBP1 | Q96B97 | SH3 domain-containing kinase-binding protein 1 | chrX | Not Cancer Driver | No | 1 | hippie | 102 | 530 | 82 | 82 | 0 |
SLMAP | SLMAP | Q14BN4 | Sarcolemmal membrane-associated protein | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 77 | 464 | 38 | 38 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 97 | 111 | 19 | 19 | 5 |
SORBS3 | SORBS3 | O60504 | Vinexin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 577 | 56 | 56 | 0 |
STRN | STRN | O43815 | Striatin | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 97 | 348 | 43 | 43 | 0 |
TACC3 | TACC3 | Q9Y6A5 | Transforming acidic coiled-coil-containing protein 3 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 707 | 81 | 81 | 0 |
THOC5_ENST00000397872 | THOC5 | Q13769 | THO complex subunit 5 homolog | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 88 | 173 | 25 | 25 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
UBE2O | UBE2O | Q9C0C9 | (E3-independent) E2 ubiquitin-conjugating enzyme | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 129 | 716 | 68 | 68 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 1 | intact | 170 | 215 | 45 | 45 | 0 |
VASP | VASP | P50552 | Vasodilator-stimulated phosphoprotein | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 39 | 335 | 34 | 34 | 0 |
WASF1_ENST00000392586 | WASF1 | Q92558 | Wiskott-Aldrich syndrome protein family member 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 445 | 49 | 49 | 0 |
WASF2 | WASF2 | Q9Y6W5 | Wiskott-Aldrich syndrome protein family member 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 400 | 43 | 43 | 0 |
WASF3 | WASF3 | Q9UPY6 | Wiskott-Aldrich syndrome protein family member 3 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 386 | 84 | 84 | 0 |
WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 108 | 9 | 9 | 3 |
WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | Not Cancer Driver | No | 1 | hippie | 112 | 422 | 57 | 57 | 0 |
YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 26 | 77 | 9 | 9 | 2 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|