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KHDRBS1 ,KHDRBS1 ,Q07666
  • Uniprot Accession= Q07666
  • Ensembl Transcript= ENST00000327300.11
  • Uniprot Name= KHDRBS1
  • Name= KH domain-containing, RNA-binding, signal transduction-associated protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 29
  • Number of Interaction partner in hippie: 304
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie 56 361 38 38 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 hippie 126 87 11 11 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 Not Cancer Driver No 1 hippie 120 500 56 56 6
ALG13 ALG13 Q9NP73 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 chrX Not Cancer Driver No 1 hippie 163 520 83 83 2
AMPH AMPH P49418 Amphiphysin chr7 Not Cancer Driver No 1 hippie 202 473 131 131 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 hippie 412 2406 345 345 22
ARHGEF4 ARHGEF4 Q9NR80 Rho guanine nucleotide exchange factor 4 chr2 Not Cancer Driver No 1 hippie 114 287 61 61 0
ARHGEF9 ARHGEF9 O43307 Rho guanine nucleotide exchange factor 9 chrX Not Cancer Driver No 1 hippie 97 88 7 7 2
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATXN2L_ENST00000336783 ATXN2L Q8WWM7 Ataxin-2-like protein chr16 Not Cancer Driver No 1 hippie, biogrid 135 1000 131 131 0
ATXN2_ENST00000550104 ATXN2 Q99700 Ataxin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 146 1228 134 134 0
AZIN1 AZIN1 O14977 Antizyme inhibitor 1 chr8 Not Cancer Driver No 1 hippie 39 10 2 2 0
BAIAP2L1 BAIAP2L1 Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 chr7 Not Cancer Driver No 1 hippie 76 293 42 42 0
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 hippie 74 311 43 43 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 50 150 30 30 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 Not Cancer Driver No 1 hippie 86 142 26 26 5
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BTBD1 BTBD1 Q9H0C5 BTB/POZ domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie 48 50 1 1 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 147 114 27 27 110
C8orf82 C8orf82 Q6P1X6 UPF0598 protein C8orf82 chr8 Not Cancer Driver No 1 hippie, biogrid 11 11 0 0 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 142 106 12 12 1
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CBX6 CBX6 O95503 Chromobox protein homolog 6 chr22 Not Cancer Driver No 1 hippie 57 335 54 54 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 Not Cancer Driver No 1 hippie 80 456 60 60 0
CD2BP2 CD2BP2 O95400 CD2 antigen cytoplasmic tail-binding protein 2 chr16 Not Cancer Driver No 1 hippie 49 259 40 40 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 hippie 100 618 77 77 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 Not Cancer Driver No 1 hippie 56 166 17 17 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 Not Cancer Driver No 1 hippie 19 129 13 13 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 Not Cancer Driver No 1 hippie 64 131 21 21 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 hippie, biogrid 163 157 18 18 4
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 Not Cancer Driver No 1 hippie 96 338 67 67 1
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 hippie 38 160 25 25 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 Not Cancer Driver No 1 hippie 76 91 5 5 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 Not Cancer Driver No 1 hippie 72 100 12 12 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie 41 18 1 1 0
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie 151 481 83 83 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 Not Cancer Driver No 1 hippie 34 13 0 0 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 Not Cancer Driver No 1 hippie, biogrid 91 362 48 48 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 hippie, biogrid 110 180 30 30 0
DHX38 DHX38 Q92620 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 chr16 Not Cancer Driver No 1 hippie, biogrid 139 622 83 83 1
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie 182 331 42 42 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 132 514 82 82 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 1 hippie 120 460 67 67 0
DLG2_ENST00000398309 DLG2 Q15700 Disks large homolog 2 chr11 Not Cancer Driver No 1 hippie 224 303 107 107 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX Not Cancer Driver No 1 hippie 94 322 30 30 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 Not Cancer Driver No 1 hippie 116 232 55 55 0
DNMBP DNMBP Q6XZF7 Dynamin-binding protein chr10 Not Cancer Driver No 1 hippie 208 758 92 92 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 Not Cancer Driver No 1 hippie 480 266 79 79 2
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 Not Cancer Driver No 1 hippie 365 458 69 69 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 Census, Compendium Yes 1 hippie 175 682 100 100 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 Not Cancer Driver No 1 hippie 31 7 0 0 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 hippie 77 294 39 39 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EFEMP1_ENST00000355426 EFEMP1 Q12805 EGF-containing fibulin-like extracellular matrix protein 1 chr2 Not Cancer Driver No 1 hippie 95 73 21 21 1
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EMG1 EMG1 Q92979 Ribosomal RNA small subunit methyltransferase NEP1 chr12 Not Cancer Driver No 1 hippie, biogrid 28 58 4 4 1
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 211 829 117 117 9
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FADD FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 26 45 10 10 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 75 20 3 3 7
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 1 hippie 85 52 8 8 0
FNBP4 FNBP4 Q8N3X1 Formin-binding protein 4 chr11 Not Cancer Driver No 1 hippie 119 926 106 106 0
FRK FRK P42685 Tyrosine-protein kinase FRK chr6 Not Cancer Driver No 1 hippie 87 18 2 2 0
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 hippie 68 388 42 42 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GAS7 GAS7 O60861 Growth arrest-specific protein 7 chr17 Census Yes 1 hippie 78 318 57 57 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX Census, Compendium Yes 1 hippie 68 242 41 41 5
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 hippie 64 299 29 29 3
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 52 24 4 4 0
GPHN_ENST00000315266 GPHN Q9NQX3 Gephyrin chr14 Census Yes 1 hippie 126 305 41 41 2
GRAP GRAP Q13588 GRB2-related adapter protein chr17 Not Cancer Driver No 1 hippie 10 0 0 0 1
GRAP2_ENST00000407075 GRAP2 O75791 GRB2-related adapter protein 2 chr22 Not Cancer Driver No 1 hippie 59 151 20 20 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 55 180 8 8 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 hippie 112 124 25 25 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 Not Cancer Driver No 1 hippie 158 565 89 89 0
HMMR_ENST00000358715 HMMR O75330 Hyaluronan mediated motility receptor chr5 Not Cancer Driver No 1 hippie 81 454 47 47 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 2 hippie, biogrid 70 290 58 58 4
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 hippie, biogrid 42 227 35 35 0
HNRNPDL HNRNPDL O14979 Heterogeneous nuclear ribonucleoprotein D-like chr4 Not Cancer Driver No 1 hippie 51 297 36 36 2
HNRNPH3 HNRNPH3 P31942 Heterogeneous nuclear ribonucleoprotein H3 chr10 Not Cancer Driver No 1 hippie 42 188 18 18 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie 75 302 59 59 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 2 hippie, biogrid 67 304 25 25 0
HNRNPUL2 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 hippie 71 418 35 35 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie 190 280 57 57 64
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 Not Cancer Driver No 1 hippie 161 1072 133 133 2
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 hippie 139 43 10 10 1
ITPRID2 ITPRID2 P28290 Protein ITPRID2 chr2 Not Cancer Driver No 1 hippie 158 1006 129 129 0
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie 214 797 107 107 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 Not Cancer Driver No 1 hippie 207 680 92 92 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 167 63 10 10 7
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie 53 362 43 43 0
KHDRBS2 KHDRBS2 Q5VWX1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 chr6 Not Cancer Driver No 3 hippie, biogrid 168 268 140 140 0
KHDRBS3 KHDRBS3 O75525 KH domain-containing, RNA-binding, signal transduction-associated protein 3 chr8 Not Cancer Driver No 2 hippie, biogrid 64 230 40 40 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie 226 83 33 33 21
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 hippie 13 204 8 8 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 149 534 114 114 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 108 16 3 3 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MATN2 MATN2 O00339 Matrilin-2 chr8 Not Cancer Driver No 1 hippie 151 167 26 26 0
MATR3_ENST00000509990 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 98 611 68 68 3
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 Not Cancer Driver No 1 hippie 39 0 0 0 5
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MED12 MED12 Q93074 Mediator of RNA polymerase II transcription subunit 12 chrX Census, Compendium Yes 1 hippie 409 974 175 175 5
MIA2_ENST00000640607 MIA2 Q96PC5 Melanoma inhibitory activity protein 2 chr14 Not Cancer Driver No 1 hippie 214 961 155 155 0
MKRN1 MKRN1 Q9UHC7 E3 ubiquitin-protein ligase makorin-1 chr7 Not Cancer Driver No 1 hippie 42 155 16 16 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 hippie 58 143 16 16 0
MPHOSPH8 MPHOSPH8 Q99549 M-phase phosphoprotein 8 chr13 Not Cancer Driver No 1 hippie 105 523 66 66 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 hippie 78 283 32 32 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 hippie 110 66 11 11 0
MYO7A MYO7A Q13402 Unconventional myosin-VIIa chr11 Not Cancer Driver No 1 hippie 298 369 58 58 50
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 hippie 37 181 12 12 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie 48 111 17 17 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 1 hippie 89 88 19 19 0
NCKAP5 NCKAP5 O14513 Nck-associated protein 5 chr2 Not Cancer Driver No 1 hippie 450 1677 408 408 0
NCKIPSD NCKIPSD Q9NZQ3 NCK-interacting protein with SH3 domain chr3 Census Yes 1 hippie 63 260 28 28 0
NCOA5 NCOA5 Q9HCD5 Nuclear receptor coactivator 5 chr20 Not Cancer Driver No 1 hippie 84 478 70 70 0
NCSTN NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 hippie, biogrid 94 72 11 11 1
NGB NGB Q9NPG2 Neuroglobin chr14 Not Cancer Driver No 1 hippie 20 3 0 0 0
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 Not Cancer Driver No 1 hippie 108 259 32 32 1
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OSTF1 OSTF1 Q92882 Osteoclast-stimulating factor 1 chr9 Not Cancer Driver No 1 hippie 18 51 2 2 0
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 Not Cancer Driver No 1 hippie 56 318 47 47 0
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 Not Cancer Driver No 1 hippie 51 301 27 27 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 Not Cancer Driver No 2 hippie, biogrid 52 290 31 31 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 hippie 65 166 24 24 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 1 hippie 80 241 43 43 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PIR_ENST00000380420 PIR O00625 Pirin chrX Not Cancer Driver No 1 hippie 29 185 16 16 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 248 142 30 30 1
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 hippie 677 2130 272 272 2
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 hippie 152 919 121 121 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 113 31 6 6 9
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 26 23 4 4 0
PPP1R13B PPP1R13B Q96KQ4 Apoptosis-stimulating of p53 protein 1 chr14 Not Cancer Driver No 1 hippie 115 821 92 92 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 Census, Compendium Yes 1 hippie 39 66 11 11 17
PRKRIP1_ENST00000397912 PRKRIP1 Q9H875 PRKR-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 22 184 22 22 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 50 18 1 1 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PSTPIP1 PSTPIP1 O43586 Proline-serine-threonine phosphatase-interacting protein 1 chr15 Not Cancer Driver No 1 hippie 46 225 26 26 3
PTBP2_ENST00000426398 PTBP2 Q9UKA9 Polypyrimidine tract-binding protein 2 chr1 Not Cancer Driver No 1 hippie 84 136 20 20 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 Census, Compendium Yes 1 hippie 243 382 67 67 18
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 42 12 0 0 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 Census, Compendium Yes 1 hippie 73 192 25 25 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 174 291 99 99 0
RALY RALY Q9UKM9 RNA-binding protein Raly chr20 Not Cancer Driver No 1 hippie 58 187 32 32 0
RAPSN RAPSN Q13702 43 kDa receptor-associated protein of the synapse chr11 Not Cancer Driver No 1 hippie 38 10 0 0 8
RARA RARA P10276 Retinoic acid receptor alpha chr17 Census, Compendium Yes 1 hippie 70 167 14 14 0
RARRES1 RARRES1 P49788 Retinoic acid receptor responder protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 24 79 3 3 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RBFOX2_ENST00000449924 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 1 hippie 44 173 22 22 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 Census, Compendium Yes 1 hippie, biogrid 118 686 91 91 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBM7_ENST00000540163 RBM7 Q9Y580 RNA-binding protein 7 chr11 Not Cancer Driver No 1 hippie 36 194 27 27 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX Not Cancer Driver No 1 hippie 82 380 81 81 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 33 23 0 0 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 1 hippie 82 277 39 39 4
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 Not Cancer Driver No 1 hippie 111 855 96 96 0
RNF181 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 Not Cancer Driver No 1 hippie 15 63 8 8 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 13 4 1 1 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 hippie 74 513 48 48 0
RUSC2 RUSC2 Q8N2Y8 AP-4 complex accessory subunit RUSC2 chr9 Not Cancer Driver No 1 hippie 161 1142 115 115 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie 174 1071 153 153 7
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 1 hippie 42 243 17 17 0
SCG5 SCG5 P05408 Neuroendocrine protein 7B2 chr15 Not Cancer Driver No 1 hippie 25 174 21 21 0
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 Not Cancer Driver No 1 hippie 110 627 106 106 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 Census Yes 1 hippie, biogrid 59 595 48 48 0
SH3GL1 SH3GL1 Q99961 Endophilin-A2 chr19 Census Yes 1 hippie 45 245 33 33 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 Not Cancer Driver No 1 hippie 76 214 50 50 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 102 530 82 82 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 141 797 101 101 0
SH3YL1 SH3YL1 Q96HL8 SH3 domain-containing YSC84-like protein 1 chr2 Not Cancer Driver No 1 hippie 35 108 11 11 0
SKAP2 SKAP2 O75563 Src kinase-associated phosphoprotein 2 chr7 Not Cancer Driver No 1 hippie 51 157 19 19 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SMARCAD1_ENST00000354268 SMARCAD1 Q9H4L7 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 chr4 Not Cancer Driver No 1 hippie 129 388 50 50 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 hippie 64 141 35 35 3
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SNRPN_ENST00000577565 SNRPN P63162 Small nuclear ribonucleoprotein-associated protein N chr15 Not Cancer Driver No 1 hippie 92 184 79 79 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SNX30 SNX30 Q5VWJ9 Sorting nexin-30 chr9 Not Cancer Driver No 1 hippie 36 98 4 4 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 Not Cancer Driver No 1 hippie 71 231 23 23 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 161 1111 133 133 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 hippie 63 332 44 44 0
SPATA13_ENST00000382095 SPATA13 Q96N96 Spermatogenesis-associated protein 13 chr13 Not Cancer Driver No 1 hippie 68 263 32 32 0
SPOP SPOP O43791 Speckle-type POZ protein chr17 Census, Compendium Yes 1 hippie 147 25 5 5 6
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 2 hippie, biogrid 53 130 11 11 1
SRP54 SRP54 P61011 Signal recognition particle 54 kDa protein chr14 Not Cancer Driver No 1 hippie 53 115 13 13 7
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie 78 343 46 46 0
SRRM1 SRRM1 Q8IYB3 Serine/arginine repetitive matrix protein 1 chr1 Not Cancer Driver No 1 hippie 129 795 122 122 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 Census Yes 1 hippie, biogrid 31 125 27 27 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie, biogrid 35 112 14 14 12
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie, biogrid 93 285 39 39 0
TBL1X TBL1X O60907 F-box-like/WD repeat-containing protein TBL1X chrX Not Cancer Driver No 1 hippie 85 181 35 35 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie 198 1350 151 151 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 hippie 58 111 15 15 12
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 Not Cancer Driver No 1 hippie 52 56 1 1 1
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TNS3 TNS3 Q68CZ2 Tensin-3 chr7 Not Cancer Driver No 1 hippie 238 864 143 143 0
TOB1 TOB1 P50616 Protein Tob1 chr17 Not Cancer Driver No 1 hippie 35 214 18 18 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 Not Cancer Driver No 1 hippie, biogrid 74 37 7 7 0
TSPOAP1 TSPOAP1 O95153 Peripheral-type benzodiazepine receptor-associated protein 1 chr17 Not Cancer Driver No 1 hippie 268 1522 213 213 0
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie, biogrid 67 53 10 10 12
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 hippie 91 61 16 16 2
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 78 191 28 28 0
UBA52_ENST00000595683 UBA52 P62987 Ubiquitin-60S ribosomal protein L40 chr19 Not Cancer Driver No 1 hippie 19 45 8 8 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 hippie 86 73 6 6 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 hippie 141 136 22 22 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
USO1_ENST00000514213 USO1 O60763 General vesicular transport factor p115 chr4 Not Cancer Driver No 1 hippie, biogrid 78 368 28 28 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 hippie 165 113 19 19 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WBP11 WBP11 Q9Y2W2 WW domain-binding protein 11 chr12 Not Cancer Driver No 1 hippie, biogrid 86 606 79 79 0
WBP4 WBP4 O75554 WW domain-binding protein 4 chr13 Not Cancer Driver No 1 hippie 44 309 37 37 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 hippie 30 41 2 2 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 hippie 41 312 41 41 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0
YLPM1 YLPM1 P49750 YLP motif-containing protein 1 chr14 Not Cancer Driver No 1 hippie 251 1985 226 226 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 137 597 117 117 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 26 77 9 9 2
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 Not Cancer Driver No 1 hippie 60 285 30 30 0
ZDHHC6 ZDHHC6 Q9H6R6 Palmitoyltransferase ZDHHC6 chr10 Not Cancer Driver No 1 hippie 43 11 3 3 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 Not Cancer Driver No 1 hippie 73 324 45 45 0
ZNF451 ZNF451 Q9Y4E5 E3 SUMO-protein ligase ZNF451 chr6 Not Cancer Driver No 1 hippie 169 191 25 25 0