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KDM5B_ENST00000367265 ,KDM5B ,Q9UGL1
  • Uniprot Accession= Q9UGL1
  • Ensembl Transcript= ENST00000367265.7
  • Uniprot Name= KDM5B
  • Name= Lysine-specific demethylase 5B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 7
  • Number of Interaction partner in hippie: 83
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCA4 ABCA4 P78363 Retinal-specific phospholipid-transporting ATPase ABCA4 chr1 Not Cancer Driver No 1 intact 363 244 33 33 226
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact 73 29 5 5 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARID1B_ENST00000350026 ARID1B Q8NFD5 AT-rich interactive domain-containing protein 1B chr6 Census, Compendium Yes 1 hippie 251 1890 206 206 0
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 Census, Compendium Yes 1 hippie 114 547 77 77 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 Not Cancer Driver No 1 hippie 124 827 89 89 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 Not Cancer Driver No 1 hippie 436 1144 132 132 46
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 Not Cancer Driver No 1 hippie 323 1045 141 141 18
CALML5 CALML5 Q9NZT1 Calmodulin-like protein 5 chr10 Not Cancer Driver No 1 intact 34 98 21 21 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 intact 30 2 0 0 0
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 hippie 72 477 63 63 0
CDC14A_ENST00000336454 CDC14A Q9UNH5 Dual specificity protein phosphatase CDC14A chr1 Not Cancer Driver No 1 intact 91 246 43 43 3
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie 44 198 15 15 0
CDX2 CDX2 Q99626 Homeobox protein CDX-2 chr13 Census, Compendium Yes 1 hippie 39 271 35 35 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHST3 CHST3 Q7LGC8 Carbohydrate sulfotransferase 3 chr10 Not Cancer Driver No 1 intact 49 55 4 4 5
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 Not Cancer Driver No 1 hippie, biogrid 36 244 34 34 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 Not Cancer Driver No 1 intact 31 16 3 3 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie 151 481 83 83 1
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 Not Cancer Driver No 1 hippie 46 304 31 31 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 Not Cancer Driver No 1 hippie 56 264 11 11 0
DHX37 DHX37 Q8IY37 Probable ATP-dependent RNA helicase DHX37 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 165 433 66 66 5
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DNAJB12_ENST00000444643 DNAJB12 Q9NXW2 DnaJ homolog subfamily B member 12 chr10 Not Cancer Driver No 1 intact 43 227 20 20 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELF3_ENST00000367283 ELF3 P78545 ETS-related transcription factor Elf-3 chr1 Census, Compendium Yes 1 intact 94 145 34 34 0
ELF4 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX Census, Compendium Yes 1 hippie 88 486 60 60 0
ESRP1_ENST00000642581 ESRP1 Q6NXG1 Epithelial splicing regulatory protein 1 chr8 Not Cancer Driver No 1 intact 120 41 5 5 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FAM90A1 FAM90A1 Q86YD7 Protein FAM90A1 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 123 461 121 121 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 75 20 3 3 7
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 Not Cancer Driver No 1 hippie 63 369 33 33 1
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 Not Cancer Driver No 1 hippie 132 322 79 79 2
FST FST P19883 Follistatin chr5 Not Cancer Driver No 1 intact 50 20 7 7 0
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 Not Cancer Driver No 1 hippie 413 426 147 147 11
GTF2A1 GTF2A1 P52655 Transcription initiation factor IIA subunit 1 chr14 Not Cancer Driver No 1 hippie 49 260 38 38 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 hippie 91 570 50 50 0
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 Not Cancer Driver No 1 intact, hippie, biogrid 122 337 44 44 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 Not Cancer Driver No 1 hippie 59 349 46 46 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 1 hippie 35 14 1 1 0
MAF_ENST00000393350 MAF O75444 Transcription factor Maf chr16 Census, Compendium Yes 1 hippie 39 331 37 37 11
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 1 hippie 26 384 25 25 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 Not Cancer Driver No 1 hippie 50 246 46 46 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 hippie 70 274 63 63 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 hippie 78 283 32 32 0
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 Not Cancer Driver No 1 hippie 48 169 18 18 0
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 Census, Compendium Yes 1 hippie 71 415 64 64 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 hippie 352 2347 340 340 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 Census Yes 1 hippie 83 298 37 37 0
ONECUT2 ONECUT2 O95948 One cut domain family member 2 chr18 Not Cancer Driver No 1 hippie 76 408 54 54 0
PALD1 PALD1 Q9ULE6 Paladin chr10 Not Cancer Driver No 1 intact 132 154 21 21 0
PAX9 PAX9 P55771 Paired box protein Pax-9 chr14 Not Cancer Driver No 1 hippie 52 198 32 32 1
PCNX1 PCNX1 Q96RV3 Pecanex-like protein 1 chr14 Not Cancer Driver No 1 hippie 281 1059 127 127 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLPBP PLPBP O94903 Pyridoxal phosphate homeostasis protein chr8 Not Cancer Driver No 1 intact, hippie 30 96 12 12 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact, hippie 38 27 6 6 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRDM13 PRDM13 Q9H4Q3 PR domain zinc finger protein 13 chr6 Not Cancer Driver No 1 hippie 92 416 48 48 0
PRPF4 PRPF4 O43172 U4/U6 small nuclear ribonucleoprotein Prp4 chr9 Not Cancer Driver No 1 hippie, biogrid 61 152 15 15 2
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 Not Cancer Driver No 1 intact 102 18 3 3 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie 53 169 23 23 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 hippie 67 138 19 19 0
RBM15B RBM15B Q8NDT2 Putative RNA-binding protein 15B chr3 Not Cancer Driver No 1 hippie 76 597 48 48 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 Not Cancer Driver No 1 hippie 47 324 28 28 0
RHOBTB2_ENST00000251822 RHOBTB2 Q9BYZ6 Rho-related BTB domain-containing protein 2 chr8 Not Cancer Driver No 1 hippie 99 131 18 18 6
RNF43_ENST00000577716 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 Census, Compendium Yes 1 hippie 121 437 54 54 0
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 Not Cancer Driver No 1 hippie 67 200 40 40 0
SLC39A6_ENST00000590986 SLC39A6 Q13433 Zinc transporter ZIP6 chr18 Not Cancer Driver No 1 hippie 86 360 37 37 0
SLITRK3 SLITRK3 O94933 SLIT and NTRK-like protein 3 chr3 Not Cancer Driver No 1 hippie 335 321 127 127 0
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 Not Cancer Driver No 1 hippie 175 876 133 133 4
SNAPC4 SNAPC4 Q5SXM2 snRNA-activating protein complex subunit 4 chr9 Not Cancer Driver No 1 hippie, biogrid 143 1094 96 96 0
SPDEF SPDEF O95238 SAM pointed domain-containing Ets transcription factor chr6 Not Cancer Driver No 1 intact 47 110 24 24 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 hippie 129 241 34 34 1
TFAP2C TFAP2C Q92754 Transcription factor AP-2 gamma chr20 Not Cancer Driver No 1 hippie 76 282 41 41 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 Not Cancer Driver No 1 intact 63 47 8 8 3
TMEM121B TMEM121B Q9BXQ6 Transmembrane protein 121B chr22 Not Cancer Driver No 1 hippie 26 203 4 4 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TSPYL6 TSPYL6 Q8N831 Testis-specific Y-encoded-like protein 6 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 78 204 38 38 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
USP38 USP38 Q8NB14 Ubiquitin carboxyl-terminal hydrolase 38 chr4 Not Cancer Driver No 1 hippie 94 180 21 21 0
VGLL3 VGLL3 A8MV65 Transcription cofactor vestigial-like protein 3 chr3 Not Cancer Driver No 1 hippie 98 273 85 85 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 Not Cancer Driver No 1 intact 77 37 5 5 0
ZNF217 ZNF217 O75362 Zinc finger protein 217 chr20 Not Cancer Driver No 1 hippie 169 760 136 136 0