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KDM4A ,KDM4A ,O75164
  • Uniprot Accession= O75164
  • Ensembl Transcript= ENST00000372396.3
  • Uniprot Name= KDM4A
  • Name= Lysine-specific demethylase 4A
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 48
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 71
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 34 18 1 1 4
AFAP1L1 AFAP1L1 Q8TED9 Actin filament-associated protein 1-like 1 chr5 Not Cancer Driver No 1 hippie, biogrid 109 402 58 58 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 41 83 12 12 9
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie 27 92 10 10 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 1 hippie, biogrid 40 41 2 2 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 Not Cancer Driver No 1 hippie, biogrid 10 7 0 0 0
CCL22 CCL22 O00626 C-C motif chemokine 22 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 19 0 0 0 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie 40 1 0 0 0
CHAF1B CHAF1B Q13112 Chromatin assembly factor 1 subunit B chr21 Not Cancer Driver No 1 hippie, biogrid 65 186 30 30 0
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 Not Cancer Driver No 1 hippie, biogrid 36 244 34 34 0
CSTA CSTA P01040 Cystatin-A chr3 Not Cancer Driver No 1 hippie, biogrid 16 54 9 9 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 2 intact, hippie 151 65 9 9 0
DCD_ENST00000293371 DCD P81605 Dermcidin chr12 Not Cancer Driver No 1 hippie, biogrid 25 67 19 19 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 intact 126 50 8 8 4
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 50 152 21 21 0
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 19 128 8 8 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 186 119 17 17 7
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 intact, hippie 95 296 54 54 0
FBXL4_ENST00000229971 FBXL4 Q9UKA2 F-box/LRR-repeat protein 4 chr6 Not Cancer Driver No 1 hippie 82 23 2 2 7
FBXO22 FBXO22 Q8NEZ5 F-box only protein 22 chr15 Not Cancer Driver No 1 hippie 65 15 3 3 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 25 31 14 14 0
HIST3H3 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 37 51 10 10 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 2 intact 21 31 7 7 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 Not Cancer Driver No 1 hippie 122 337 44 44 0
KDM4B KDM4B O94953 Lysine-specific demethylase 4B chr19 Not Cancer Driver No 2 intact, hippie, biogrid 133 429 49 49 3
KDM4C KDM4C Q9H3R0 Lysine-specific demethylase 4C chr9 Not Cancer Driver No 1 hippie 124 309 40 40 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 Not Cancer Driver No 1 intact, hippie, biogrid 219 388 58 58 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 intact, hippie 104 275 38 38 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 Not Cancer Driver No 1 intact, hippie 92 310 47 47 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 1 intact, hippie 121 215 35 35 0
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 intact, hippie 88 109 20 20 1
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 intact, hippie 101 128 22 22 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MYL12B_ENST00000237500 MYL12B O14950 Myosin regulatory light chain 12B chr18 Not Cancer Driver No 1 intact, hippie, biogrid 23 61 13 13 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 hippie 352 2347 340 340 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PLPBP PLPBP O94903 Pyridoxal phosphate homeostasis protein chr8 Not Cancer Driver No 1 intact, hippie 30 96 12 12 3
POC1B POC1B Q8TC44 POC1 centriolar protein homolog B chr12 Not Cancer Driver No 1 intact, hippie, biogrid 52 86 8 8 1
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX Not Cancer Driver No 1 intact, hippie 185 347 45 45 3
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 179 214 31 31 2
POLDIP3_ENST00000252115 POLDIP3 Q9BY77 Polymerase delta-interacting protein 3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 39 301 29 29 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 Census, Compendium Yes 1 intact, hippie 409 239 44 44 3
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 23 23 3 3 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 Not Cancer Driver No 1 hippie 45 39 6 6 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 Not Cancer Driver No 1 hippie 58 50 8 8 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 Not Cancer Driver No 1 hippie 38 20 1 1 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 Not Cancer Driver No 1 hippie 77 471 66 66 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 Not Cancer Driver No 1 hippie 56 226 29 29 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie, biogrid 18 76 7 7 0
SNRPD2_ENST00000588301 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 19 67 12 12 0
SPRR1B SPRR1B P22528 Cornifin-B chr1 Not Cancer Driver No 1 intact, hippie, biogrid 24 73 20 20 0
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 41 198 34 34 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 27 0 0 0 6
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 2 intact, hippie, biogrid 75 135 14 14 9
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 70 231 30 30 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 254 781 156 156 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 102 151 17 17 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 intact, hippie 2891 282 1466 1466 83
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 Not Cancer Driver No 1 intact, hippie, biogrid 59 244 54 54 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 intact, hippie 554 402 59 59 8
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 intact, hippie, biogrid 41 52 9 9 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 intact, hippie 146 329 36 36 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX Census, Compendium Yes 1 hippie 75 400 55 55 30
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 Not Cancer Driver No 1 hippie, biogrid 61 125 19 19 0
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 Not Cancer Driver No 1 intact, hippie 50 292 7 7 0
ZNF131 ZNF131 P52739 Zinc finger protein 131 chr5 Not Cancer Driver No 1 hippie 79 266 41 41 0
ZNF414_ENST00000255616 ZNF414 Q96IQ9 Zinc finger protein 414 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 24 240 19 19 0