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ITGB3BP_ENST00000271002 ,ITGB3BP ,Q13352
  • Uniprot Accession= Q13352
  • Ensembl Transcript= ENST00000271002.14
  • Uniprot Name= ITGB3BP
  • Name= Centromere protein R
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 13
  • Number of Interaction partner in hippie: 105
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCF1 ABCF1 Q8NE71 ATP-binding cassette sub-family F member 1 chr6 Not Cancer Driver No 1 hippie 106 445 64 64 0
ACAP3 ACAP3 Q96P50 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 chr1 Not Cancer Driver No 1 hippie 68 216 7 7 0
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 hippie 73 42 10 10 16
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 Not Cancer Driver No 1 hippie 227 131 29 29 9
AKT1S1_ENST00000391834 AKT1S1 Q96B36 Proline-rich AKT1 substrate 1 chr19 Not Cancer Driver No 1 hippie 23 256 23 23 0
ALDH2 ALDH2 P05091 Aldehyde dehydrogenase, mitochondrial chr12 Census Yes 1 hippie 60 44 1 1 0
ANKRD11_ENST00000642600 ANKRD11 Q6UB99 Ankyrin repeat domain-containing protein 11 chr16 Not Cancer Driver No 1 hippie 362 2289 299 299 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARFIP2_ENST00000254584 ARFIP2 P53365 Arfaptin-2 chr11 Not Cancer Driver No 1 hippie 37 144 15 15 0
ATP5MF ATP5MF P56134 ATP synthase subunit f, mitochondrial chr7 Not Cancer Driver No 1 hippie 22 0 0 0 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 Not Cancer Driver No 1 hippie 14 15 1 1 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie 98 861 79 79 0
C14orf119 C14orf119 Q9NWQ9 Uncharacterized protein C14orf119 chr14 Not Cancer Driver No 1 hippie 13 22 3 3 0
C2CD5_ENST00000333957 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 Not Cancer Driver No 1 hippie 136 250 40 40 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 Not Cancer Driver No 1 hippie 45 186 19 19 0
CENPH CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie, biogrid 28 85 7 7 0
CENPI_ENST00000423383 CENPI Q92674 Centromere protein I chrX Not Cancer Driver No 1 hippie 107 82 7 7 0
CENPK_ENST00000514814 CENPK Q9BS16 Centromere protein K chr5 Not Cancer Driver No 1 hippie 28 91 8 8 0
CENPN_ENST00000305850 CENPN Q96H22 Centromere protein N chr16 Not Cancer Driver No 1 hippie 47 22 5 5 0
CENPO_ENST00000260662 CENPO Q9BU64 Centromere protein O chr2 Not Cancer Driver No 4 hippie, biogrid 23 54 5 5 0
CENPP CENPP Q6IPU0 Centromere protein P chr9 Not Cancer Driver No 4 hippie, biogrid 30 40 4 4 0
CENPQ CENPQ Q7L2Z9 Centromere protein Q chr6 Not Cancer Driver No 3 hippie, biogrid 33 183 23 23 0
CENPT_ENST00000440851 CENPT Q96BT3 Centromere protein T chr16 Not Cancer Driver No 1 hippie 59 468 55 55 0
CENPU CENPU Q71F23 Centromere protein U chr4 Not Cancer Driver No 3 hippie, biogrid 51 298 42 42 0
CEP126 CEP126 Q9P2H0 Centrosomal protein of 126 kDa chr11 Not Cancer Driver No 1 hippie 197 840 151 151 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 Census Yes 2 hippie, biogrid 11 19 0 0 0
COBLL1_ENST00000375458 COBLL1 Q53SF7 Cordon-bleu protein-like 1 chr2 Not Cancer Driver No 1 hippie 165 951 150 150 0
COG1 COG1 Q8WTW3 Conserved oligomeric Golgi complex subunit 1 chr17 Not Cancer Driver No 1 hippie 88 204 18 18 0
CRELD1_ENST00000383811 CRELD1 Q96HD1 Protein disulfide isomerase CRELD1 chr3 Not Cancer Driver No 1 hippie 45 44 7 7 4
DDX24 DDX24 Q9GZR7 ATP-dependent RNA helicase DDX24 chr14 Not Cancer Driver No 1 hippie, biogrid 86 452 40 40 0
DGCR8 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 Census, Compendium Yes 1 hippie, biogrid 102 466 57 57 0
DNALI1 DNALI1 A0A499FIY3 Axonemal dynein light intermediate polypeptide 1 chr1 Not Cancer Driver No 1 hippie 28 192 16 16 0
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie 79 78 15 15 17
ENOX1 ENOX1 Q8TC92 Ecto-NOX disulfide-thiol exchanger 1 chr13 Not Cancer Driver No 1 hippie 130 321 70 70 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 hippie 173 241 26 26 37
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 45 245 33 33 0
FUNDC2 FUNDC2 Q9BWH2 FUN14 domain-containing protein 2 chrX Not Cancer Driver No 1 hippie 28 34 3 3 0
GATM GATM P50440 Glycine amidinotransferase, mitochondrial chr15 Not Cancer Driver No 1 hippie 69 33 8 8 15
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 1 hippie 67 434 42 42 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
GTPBP3_ENST00000324894 GTPBP3 Q969Y2 tRNA modification GTPase GTPBP3, mitochondrial chr19 Not Cancer Driver No 1 hippie 58 155 20 20 7
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie 137 510 70 70 0
HPF1 HPF1 Q9NWY4 Histone PARylation factor 1 chr4 Not Cancer Driver No 1 hippie 32 23 0 0 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 Not Cancer Driver No 1 hippie 59 335 37 37 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 hippie 52 23 3 3 1
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 Not Cancer Driver No 1 hippie 124 66 5 5 30
ITGB3BP_ENST00000271002 ITGB3BP Q13352 Centromere protein R chr1 Not Cancer Driver No 1 hippie 19 122 14 14 0
ITGB5 ITGB5 P18084 Integrin beta-5 chr3 Not Cancer Driver No 1 hippie 86 27 3 3 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KIAA0930_ENST00000336156 KIAA0930 Q6ICG6 Uncharacterized protein KIAA0930 chr22 Not Cancer Driver No 1 hippie 51 148 23 23 0
KIFC3_ENST00000379655 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 1 hippie 84 487 42 42 0
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 Not Cancer Driver No 1 hippie 57 308 38 38 2
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
LSAMP LSAMP Q13449 Limbic system-associated membrane protein chr3 Not Cancer Driver No 1 hippie 84 112 19 19 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 Not Cancer Driver No 1 hippie 59 90 8 8 0
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 75 483 74 74 46
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 Not Cancer Driver No 1 hippie 94 358 76 76 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 hippie 70 274 63 63 0
MRPS31 MRPS31 Q92665 28S ribosomal protein S31, mitochondrial chr13 Not Cancer Driver No 1 hippie 46 231 28 28 0
MSGN1 MSGN1 A6NI15 Mesogenin-1 chr2 Not Cancer Driver No 1 hippie 54 161 44 44 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 Not Cancer Driver No 1 hippie 92 327 42 42 0
NCBP3 NCBP3 Q53F19 Nuclear cap-binding protein subunit 3 chr17 Not Cancer Driver No 1 hippie 52 507 42 42 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 hippie 104 344 38 38 0
NRDE2 NRDE2 Q9H7Z3 Nuclear exosome regulator NRDE2 chr14 Not Cancer Driver No 1 hippie 135 373 50 50 0
NUP58 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 hippie 76 377 49 49 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
OS9 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 1 hippie 72 451 49 49 0
PBX3 PBX3 P40426 Pre-B-cell leukemia transcription factor 3 chr9 Not Cancer Driver No 1 hippie 59 290 40 40 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie 70 43 6 6 20
PIH1D2 PIH1D2 Q8WWB5 PIH1 domain-containing protein 2 chr11 Not Cancer Driver No 1 hippie 33 55 5 5 0
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 Not Cancer Driver No 1 hippie 99 392 49 49 0
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 1 hippie 63 102 16 16 0
PPHLN1_ENST00000610488 PPHLN1 Q8NEY8 Periphilin-1 chr12 Not Cancer Driver No 1 hippie 64 447 62 62 0
PSME1_ENST00000206451 PSME1 Q06323 Proteasome activator complex subunit 1 chr14 Not Cancer Driver No 1 hippie 20 80 8 8 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie 31 43 4 4 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 Not Cancer Driver No 1 hippie, biogrid 132 495 71 71 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 Not Cancer Driver No 1 hippie 287 1355 164 164 0
RPL13_ENST00000393099 RPL13 P26373 60S ribosomal protein L13 chr16 Not Cancer Driver No 1 hippie, biogrid 14 160 11 11 1
RPL28_ENST00000559463 RPL28 P46779 60S ribosomal protein L28 chr19 Not Cancer Driver No 1 hippie, biogrid 29 115 24 24 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie, biogrid 49 222 31 31 0
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 hippie 41 159 24 24 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 Compendium Yes 1 hippie 90 184 26 26 0
RXRG RXRG P48443 Retinoic acid receptor RXR-gamma chr1 Not Cancer Driver No 1 hippie 103 161 41 41 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 Not Cancer Driver No 1 hippie 48 187 30 30 0
SNAPC5_ENST00000395589 SNAPC5 O75971 snRNA-activating protein complex subunit 5 chr15 Not Cancer Driver No 1 hippie 9 95 9 9 0
SUOX_ENST00000356124 SUOX P51687 Sulfite oxidase, mitochondrial chr12 Not Cancer Driver No 1 hippie 68 184 32 32 11
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie 308 1423 192 192 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 Not Cancer Driver No 1 hippie 69 207 30 30 2
TRIML2 TRIML2 Q8N7C3 Probable E3 ubiquitin-protein ligase TRIML2 chr4 Not Cancer Driver No 1 hippie 165 77 28 28 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 hippie 129 716 68 68 0
UBR7 UBR7 Q8N806 Putative E3 ubiquitin-protein ligase UBR7 chr14 Not Cancer Driver No 1 hippie 41 103 13 13 0
UPF3B UPF3B Q9BZI7 Regulator of nonsense transcripts 3B chrX Not Cancer Driver No 1 hippie 98 428 91 91 1
UQCRB_ENST00000287022 UQCRB P14927 Cytochrome b-c1 complex subunit 7 chr8 Not Cancer Driver No 1 hippie 28 2 1 1 0
USHBP1 USHBP1 Q8N6Y0 Usher syndrome type-1C protein-binding protein 1 chr19 Not Cancer Driver No 1 hippie 118 583 95 95 0
USP20_ENST00000358355 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 Not Cancer Driver No 1 hippie 112 295 36 36 0
USP33_ENST00000357428 USP33 Q8TEY7 Ubiquitin carboxyl-terminal hydrolase 33 chr1 Not Cancer Driver No 1 hippie 138 256 48 48 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 hippie 105 203 10 10 39