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INTS7 ,INTS7 ,Q9NVH2
  • Uniprot Accession= Q9NVH2
  • Ensembl Transcript= ENST00000366994.7
  • Uniprot Name= INTS7
  • Name= Integrator complex subunit 7
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 29
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 90
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 Not Cancer Driver No 1 hippie 63 163 23 23 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BUB3 BUB3 O43684 Mitotic checkpoint protein BUB3 chr10 Not Cancer Driver No 1 intact, hippie 46 60 6 6 0
CA8 CA8 P35219 Carbonic anhydrase-related protein chr8 Not Cancer Driver No 1 hippie 56 32 2 2 1
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 Not Cancer Driver No 1 hippie, biogrid 42 60 5 5 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 Not Cancer Driver No 1 hippie, biogrid 105 18 6 6 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 Not Cancer Driver No 1 hippie, biogrid 79 47 11 11 0
CD3D CD3D P04234 T-cell surface glycoprotein CD3 delta chain chr11 Not Cancer Driver No 1 hippie, biogrid 23 2 1 1 0
CD79B_ENST00000006750 CD79B P40259 B-cell antigen receptor complex-associated protein beta chain chr17 Census, Compendium Yes 2 intact, hippie, biogrid 25 43 10 10 1
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 intact, hippie 198 634 64 64 0
CLEC14A CLEC14A Q86T13 C-type lectin domain family 14 member A chr14 Not Cancer Driver No 2 hippie, biogrid 147 182 60 60 0
CLEC4C_ENST00000360345 CLEC4C Q8WTT0 C-type lectin domain family 4 member C chr12 Not Cancer Driver No 1 hippie, biogrid 58 5 1 1 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 Not Cancer Driver No 1 hippie 121 624 87 87 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 hippie 57 167 24 24 0
DGCR2 DGCR2 P98153 Integral membrane protein DGCR2/IDD chr22 Not Cancer Driver No 1 hippie, biogrid 90 178 24 24 0
DLK1 DLK1 P80370 Protein delta homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 81 0 0 0 0
ELOA_ENST00000613537 ELOA Q14241 Elongin-A chr1 Not Cancer Driver No 1 hippie 77 652 62 62 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EVI2A_ENST00000461237 EVI2A P22794 Protein EVI2A chr17 Not Cancer Driver No 1 hippie, biogrid 31 131 22 22 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 3 hippie, biogrid 54 171 16 16 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FGD1 FGD1 P98174 FYVE, RhoGEF and PH domain-containing protein 1 chrX Not Cancer Driver No 1 intact, hippie 139 520 74 74 5
FNDC4 FNDC4 Q9H6D8 Fibronectin type III domain-containing protein 4 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 25 141 19 19 0
GOLT1B GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 intact, hippie 26 0 0 0 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 Not Cancer Driver No 3 hippie, biogrid 37 30 4 4 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 intact, hippie 39 206 19 19 0
HS3ST4 HS3ST4 Q9Y661 Heparan sulfate glucosamine 3-O-sulfotransferase 4 chr16 Not Cancer Driver No 1 hippie, biogrid 115 216 18 18 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 69 0 0 0 0
INTS1 INTS1 Q8N201 Integrator complex subunit 1 chr7 Not Cancer Driver No 2 hippie, biogrid 234 368 43 43 1
INTS10 INTS10 Q9NVR2 Integrator complex subunit 10 chr8 Not Cancer Driver No 2 intact, hippie 61 49 6 6 0
INTS11_ENST00000435064 INTS11 Q5TA45 Integrator complex subunit 11 chr1 Not Cancer Driver No 1 hippie 64 24 2 2 0
INTS13 INTS13 Q9NVM9 Integrator complex subunit 13 chr12 Not Cancer Driver No 2 intact, hippie 89 300 44 44 0
INTS2 INTS2 Q9H0H0 Integrator complex subunit 2 chr17 Not Cancer Driver No 2 hippie, biogrid 149 97 8 8 0
INTS3_ENST00000435409 INTS3 Q68E01 Integrator complex subunit 3 chr1 Not Cancer Driver No 1 hippie 125 213 25 25 0
INTS5 INTS5 Q6P9B9 Integrator complex subunit 5 chr11 Not Cancer Driver No 2 hippie, biogrid 123 189 22 22 0
INTS6 INTS6 Q9UL03 Integrator complex subunit 6 chr13 Not Cancer Driver No 1 hippie 96 389 49 49 0
INTS8 INTS8 Q75QN2 Integrator complex subunit 8 chr8 Not Cancer Driver No 1 hippie, biogrid 104 102 10 10 1
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 Not Cancer Driver No 1 hippie, biogrid 35 24 10 10 9
KIF1C KIF1C O43896 Kinesin-like protein KIF1C chr17 Not Cancer Driver No 1 intact, hippie 131 695 94 94 1
KLRG2 KLRG2 A4D1S0 Killer cell lectin-like receptor subfamily G member 2 chr7 Not Cancer Driver No 1 hippie, biogrid 51 238 30 30 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LRRC25_ENST00000595840 LRRC25 Q8N386 Leucine-rich repeat-containing protein 25 chr19 Not Cancer Driver No 1 hippie, biogrid 40 89 14 14 0
MGARP MGARP Q8TDB4 Protein MGARP chr4 Not Cancer Driver No 1 hippie, biogrid 25 207 22 22 0
MGRN1_ENST00000399577 MGRN1 O60291 E3 ubiquitin-protein ligase MGRN1 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 76 228 37 37 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 Census, Compendium Yes 3 intact, hippie, biogrid 159 528 132 132 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 2 intact, hippie, biogrid 249 57 21 21 0
OPALIN OPALIN Q96PE5 Opalin chr10 Not Cancer Driver No 1 hippie, biogrid 29 86 18 18 0
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 26 101 9 9 5
PALD1 PALD1 Q9ULE6 Paladin chr10 Not Cancer Driver No 1 hippie, biogrid 132 154 21 21 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 120 461 39 39 0
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 56 141 37 37 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PMEL_ENST00000552882 PMEL P40967 Melanocyte protein PMEL chr12 Not Cancer Driver No 2 intact, hippie, biogrid 83 180 15 15 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 intact, hippie 112 312 34 34 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 intact, hippie 41 12 1 1 8
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 intact, hippie 179 0 0 0 4
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 68 320 41 41 0
RALA RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 34 34 3 3 5
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 Not Cancer Driver No 1 hippie, biogrid 56 293 25 25 0
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 63 16 5 5 3
SEM1_ENST00000356686 SEM1 Q6ZVN7 Putative protein SEM1, isoform 2 chr7 Not Cancer Driver No 1 hippie 2 52 1 1 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 Not Cancer Driver No 2 hippie, biogrid 82 64 10 10 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 Not Cancer Driver No 1 hippie, biogrid 19 318 16 16 4
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SPACA1 SPACA1 Q9HBV2 Sperm acrosome membrane-associated protein 1 chr6 Not Cancer Driver No 3 hippie, biogrid 65 79 9 9 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie 27 0 0 0 6
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 Not Cancer Driver No 1 hippie, biogrid 22 27 1 1 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 intact, hippie 42 302 26 26 0
TMEFF1 TMEFF1 Q8IYR6 Tomoregulin-1 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 50 65 9 9 0
TMEM154 TMEM154 Q6P9G4 Transmembrane protein 154 chr4 Not Cancer Driver No 1 hippie, biogrid 22 88 9 9 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 Not Cancer Driver No 1 intact 46 66 13 13 3
TMEM74 TMEM74 Q96NL1 Transmembrane protein 74 chr8 Not Cancer Driver No 1 hippie, biogrid 93 127 42 42 0
TMEM9_ENST00000485839 TMEM9 Q9P0T7 Proton-transporting V-type ATPase complex assembly regulator TMEM9 chr1 Not Cancer Driver No 1 hippie, biogrid 22 23 3 3 0
TNFRSF17 TNFRSF17 Q02223 Tumor necrosis factor receptor superfamily member 17 chr16 Census Yes 2 hippie, biogrid 28 1 0 0 0
TNFSF8 TNFSF8 P32971 Tumor necrosis factor ligand superfamily member 8 chr9 Not Cancer Driver No 1 hippie, biogrid 34 30 2 2 0
TOR1AIP2_ENST00000482587 TOR1AIP2 Q9H496 Torsin-1A-interacting protein 2, isoform IFRG15 chr1 Not Cancer Driver No 2 hippie, biogrid 12 7 0 0 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM52 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 Not Cancer Driver No 1 hippie, biogrid 23 147 13 13 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UPK2 UPK2 O00526 Uroplakin-2 chr11 Not Cancer Driver No 1 hippie, biogrid 15 9 1 1 0
VPS26A_ENST00000263559 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 intact, hippie 27 44 2 2 0
VSIG1_ENST00000217957 VSIG1 Q86XK7 V-set and immunoglobulin domain-containing protein 1 chrX Not Cancer Driver No 2 hippie, biogrid 55 137 20 20 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX Not Cancer Driver No 3 intact, hippie, biogrid 73 70 13 13 0
VSTM1 VSTM1 Q6UX27 V-set and transmembrane domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 72 126 40 40 0
ZP2 ZP2 Q05996 Zona pellucida sperm-binding protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 129 65 14 14 0