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INTS11_ENST00000435064 ,INTS11 ,Q5TA45
  • Uniprot Accession= Q5TA45
  • Ensembl Transcript= ENST00000435064.5
  • Uniprot Name= INTS11
  • Name= Integrator complex subunit 11
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 40
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 84
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 21 30 1 1 0
ANXA7 ANXA7 P20073 Annexin A7 chr10 Not Cancer Driver No 1 intact, hippie 68 215 37 37 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact, hippie 17 112 9 9 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
C1orf94 C1orf94 Q6P1W5 Uncharacterized protein C1orf94 chr1 Not Cancer Driver No 1 intact, hippie 136 387 102 102 0
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 27 62 8 8 0
CCDC120_ENST00000606812 CCDC120 Q96HB5 Coiled-coil domain-containing protein 120 chrX Not Cancer Driver No 1 intact, hippie 71 555 67 67 0
COMMD5 COMMD5 Q9GZQ3 COMM domain-containing protein 5 chr8 Not Cancer Driver No 1 hippie 30 32 3 3 0
CREB5 CREB5 Q02930 Cyclic AMP-responsive element-binding protein 5 chr7 Not Cancer Driver No 1 hippie 92 494 89 89 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 20 19 0 0 4
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DHDH DHDH Q9UQ10 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase chr19 Not Cancer Driver No 1 hippie 54 18 2 2 0
DSE DSE Q9UL01 Dermatan-sulfate epimerase chr6 Not Cancer Driver No 1 intact, hippie 151 37 1 1 1
ENY2 ENY2 Q9NPA8 Transcription and mRNA export factor ENY2 chr8 Not Cancer Driver No 1 hippie 17 11 4 4 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM222B FAM222B Q8WU58 Protein FAM222B chr17 Not Cancer Driver No 1 intact, hippie 54 476 45 45 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 Not Cancer Driver No 1 intact, hippie 29 319 26 26 0
HSF4 HSF4 Q9ULV5 Heat shock factor protein 4 chr16 Not Cancer Driver No 1 intact, hippie 37 327 25 25 4
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
INF2 INF2 Q27J81 Inverted formin-2 chr14 Not Cancer Driver No 1 hippie 120 635 49 49 30
INTS1 INTS1 Q8N201 Integrator complex subunit 1 chr7 Not Cancer Driver No 1 hippie 234 368 43 43 1
INTS10 INTS10 Q9NVR2 Integrator complex subunit 10 chr8 Not Cancer Driver No 4 intact, hippie 61 49 6 6 0
INTS13 INTS13 Q9NVM9 Integrator complex subunit 13 chr12 Not Cancer Driver No 2 intact, hippie 89 300 44 44 0
INTS14_ENST00000313182 INTS14 Q96SY0 Integrator complex subunit 14 chr15 Not Cancer Driver No 1 hippie 63 118 12 12 0
INTS2 INTS2 Q9H0H0 Integrator complex subunit 2 chr17 Not Cancer Driver No 1 hippie 149 97 8 8 0
INTS3_ENST00000435409 INTS3 Q68E01 Integrator complex subunit 3 chr1 Not Cancer Driver No 2 intact, hippie 125 213 25 25 0
INTS4 INTS4 Q96HW7 Integrator complex subunit 4 chr11 Not Cancer Driver No 1 hippie 117 82 7 7 0
INTS5 INTS5 Q6P9B9 Integrator complex subunit 5 chr11 Not Cancer Driver No 1 hippie 123 189 22 22 0
INTS6 INTS6 Q9UL03 Integrator complex subunit 6 chr13 Not Cancer Driver No 1 hippie 96 389 49 49 0
INTS7 INTS7 Q9NVH2 Integrator complex subunit 7 chr1 Not Cancer Driver No 1 hippie 106 88 17 17 0
INTS9 INTS9 Q9NV88 Integrator complex subunit 9 chr8 Not Cancer Driver No 5 intact, hippie 68 50 5 5 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 hippie 65 121 18 18 0
KRTAP15-1 KRTAP15-1 Q3LI76 Keratin-associated protein 15-1 chr21 Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
KRTAP26-1 KRTAP26-1 Q6PEX3 Keratin-associated protein 26-1 chr21 Not Cancer Driver No 1 intact, hippie 54 0 0 0 0
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 29 198 24 24 0
LENG8 LENG8 Q96PV6 Leukocyte receptor cluster member 8 chr19 Not Cancer Driver No 1 intact, hippie 137 515 97 97 0
LY86 LY86 O95711 Lymphocyte antigen 86 chr6 Not Cancer Driver No 1 hippie 29 0 0 0 0
MDFI MDFI Q99750 MyoD family inhibitor chr6 Not Cancer Driver No 1 hippie 25 152 15 15 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NABP1 NABP1 Q96AH0 SOSS complex subunit B2 chr2 Not Cancer Driver No 1 intact, hippie 25 102 11 11 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 Not Cancer Driver No 1 hippie 25 125 17 17 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 Not Cancer Driver No 1 hippie 10 4 0 0 0
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 Not Cancer Driver No 1 hippie 46 287 19 19 2
OTX1_ENST00000366671 OTX1 P32242 Homeobox protein OTX1 chr2 Not Cancer Driver No 1 hippie 68 248 39 39 0
OXER1 OXER1 Q8TDS5 Oxoeicosanoid receptor 1 chr2 Not Cancer Driver No 1 intact, hippie 42 38 3 3 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 Not Cancer Driver No 1 intact, hippie 120 459 54 54 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 Not Cancer Driver No 1 intact, hippie 43 92 13 13 0
PLSCR4_ENST00000446574 PLSCR4 Q9NRQ2 Phospholipid scramblase 4 chr3 Not Cancer Driver No 1 hippie 68 108 11 11 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie 56 230 20 20 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 2 intact, hippie 41 12 1 1 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 1 intact, hippie 37 12 0 0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 2 intact, hippie 179 0 0 0 4
PROP1 PROP1 O75360 Homeobox protein prophet of Pit-1 chr5 Not Cancer Driver No 1 intact, hippie 35 194 32 32 7
PRR35 PRR35 P0CG20 Proline-rich protein 35 chr16 Not Cancer Driver No 1 intact, hippie 55 487 46 46 0
PTPRN2 PTPRN2 Q92932 Receptor-type tyrosine-protein phosphatase N2 chr7 Not Cancer Driver No 1 intact, hippie 274 580 169 169 0
RAD9B RAD9B Q6WBX8 Cell cycle checkpoint control protein RAD9B chr12 Not Cancer Driver No 1 hippie 46 40 6 6 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 intact, hippie 9 25 0 0 1
RPLP1 RPLP1 P05386 60S acidic ribosomal protein P1 chr15 Not Cancer Driver No 1 intact, hippie 6 45 2 2 0
SEM1_ENST00000356686 SEM1 Q6ZVN7 Putative protein SEM1, isoform 2 chr7 Not Cancer Driver No 1 hippie 2 52 1 1 0
SNRPC SNRPC P09234 U1 small nuclear ribonucleoprotein C chr6 Not Cancer Driver No 1 intact, hippie 26 143 26 26 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SPAG8_ENST00000396638 SPAG8 Q99932 Sperm-associated antigen 8 chr9 Not Cancer Driver No 1 intact, hippie 46 399 36 36 0
SPIC SPIC Q8N5J4 Transcription factor Spi-C chr12 Not Cancer Driver No 1 intact, hippie 43 15 1 1 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 Not Cancer Driver No 1 intact, hippie 44 253 25 25 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 1 hippie 122 516 93 93 0
TFG TFG Q92734 Protein TFG chr3 Census, Compendium Yes 1 intact, hippie 45 290 34 34 3
THBS3 THBS3 P49746 Thrombospondin-3 chr1 Not Cancer Driver No 1 hippie 100 283 24 24 0
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 Not Cancer Driver No 1 intact, hippie 26 13 4 4 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 Census Yes 1 intact, hippie 40 179 24 24 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 1 intact, hippie 62 30 6 6 1
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 Not Cancer Driver No 1 hippie 88 213 39 39 0
VAC14 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 1 hippie 97 116 19 19 3
VENTX VENTX O95231 Homeobox protein VENTX chr10 Not Cancer Driver No 1 intact, hippie 45 198 31 31 0
YPEL3_ENST00000566595 YPEL3 P61236 Protein yippee-like 3 chr16 Not Cancer Driver No 1 hippie 13 0 0 0 0
ZC3H10 ZC3H10 Q96K80 Zinc finger CCCH domain-containing protein 10 chr12 Not Cancer Driver No 1 intact, hippie 41 336 31 31 0
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 Not Cancer Driver No 1 intact, hippie 187 246 113 113 1