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IL6R ,IL6R ,P08887
  • Uniprot Accession= P08887
  • Ensembl Transcript= ENST00000368485.7
  • Uniprot Name= IL6R
  • Name= Interleukin-6 receptor subunit alpha
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 9
  • Number of Interaction partner in hippie: 28
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
C12orf4 C12orf4 Q9NQ89 Protein C12orf4 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 70 111 8 8 1
CETN2 CETN2 P41208 Centrin-2 chrX Not Cancer Driver No 2 intact, hippie, biogrid 33 97 11 11 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 Not Cancer Driver No 1 hippie 41 34 5 5 0
COPRS COPRS Q9NQ92 Coordinator of PRMT5 and differentiation stimulator chr17 Not Cancer Driver No 2 intact, hippie, biogrid 15 181 15 15 0
CRYZL1 CRYZL1 O95825 Quinone oxidoreductase-like protein 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 30 1 0 0 0
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 Not Cancer Driver No 1 intact, hippie 78 70 2 2 0
FAAP100 FAAP100 Q0VG06 Fanconi anemia core complex-associated protein 100 chr17 Not Cancer Driver No 1 intact, hippie 93 207 31 31 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX Not Cancer Driver No 2 intact, hippie, biogrid 109 24 5 5 0
FANCL_ENST00000233741 FANCL Q9NW38 E3 ubiquitin-protein ligase FANCL chr2 Not Cancer Driver No 2 intact, hippie, biogrid 47 11 0 0 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie 21 75 1 1 0
GATD1 GATD1 Q8NB37 Glutamine amidotransferase-like class 1 domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 24 2 0 0 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
IL6 IL6 P05231 Interleukin-6 chr7 Not Cancer Driver No 1 hippie 35 58 7 7 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 Not Cancer Driver No 1 hippie 55 165 23 23 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 Census, Compendium Yes 2 intact, hippie 102 315 40 40 2
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 Census, Compendium Yes 1 intact, hippie 147 120 7 7 2
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 260 1212 220 220 0
MID1 MID1 O15344 E3 ubiquitin-protein ligase Midline-1 chrX Not Cancer Driver No 1 intact, hippie, biogrid 86 86 16 16 4
PPP1R21 PPP1R21 Q6ZMI0 Protein phosphatase 1 regulatory subunit 21 chr2 Not Cancer Driver No 2 hippie, biogrid 86 315 33 33 0
PSMD9 PSMD9 O00233 26S proteasome non-ATPase regulatory subunit 9 chr12 Not Cancer Driver No 1 hippie 22 173 16 16 0
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 Not Cancer Driver No 1 hippie 374 87 10 10 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 Not Cancer Driver No 2 intact, hippie, biogrid 115 88 9 9 2
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie 139 431 75 75 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0