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IKBKG_ENST00000611071 ,IKBKG ,Q9Y6K9
  • Uniprot Accession= Q9Y6K9
  • Ensembl Transcript= ENST00000611071.4
  • Uniprot Name= IKBKG
  • Name= NF-kappa-B essential modulator
  • Chromosome= chrX
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 250
  • Number of Interaction partner in biogrid: 41
  • Number of Interaction partner in hippie: 510
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 Not Cancer Driver No 1 hippie 284 245 40 40 31
ACAP1 ACAP1 Q15027 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 chr17 Not Cancer Driver No 1 hippie 95 266 37 37 0
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 Not Cancer Driver No 1 hippie 97 287 40 40 0
ACBD6_ENST00000367595 ACBD6 Q9BR61 Acyl-CoA-binding domain-containing protein 6 chr1 Not Cancer Driver No 1 intact, hippie 22 58 5 5 0
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 2 intact, hippie 73 42 10 10 16
ADAP2 ADAP2 Q9NPF8 Arf-GAP with dual PH domain-containing protein 2 chr17 Not Cancer Driver No 1 intact, hippie 42 30 5 5 0
AIP AIP O00170 AH receptor-interacting protein chr11 Not Cancer Driver No 1 hippie 32 64 9 9 1
AKR7A2 AKR7A2 O43488 Aflatoxin B1 aldehyde reductase member 2 chr1 Not Cancer Driver No 1 hippie 35 90 3 3 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 intact, hippie 108 158 24 24 4
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 hippie 303 575 114 114 16
ALMS1 ALMS1 Q8TCU4 Alstrom syndrome protein 1 chr2 Not Cancer Driver No 1 intact, hippie 537 3518 441 441 0
AMMECR1L_ENST00000393001 AMMECR1L Q6DCA0 AMMECR1-like protein chr2 Not Cancer Driver No 1 intact, hippie 44 84 6 6 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 intact, hippie 161 909 128 128 0
AMOTL1 AMOTL1 Q8IY63 Angiomotin-like protein 1 chr11 Not Cancer Driver No 1 intact, hippie 136 851 121 121 0
ANGPTL8_ENST00000252453 ANGPTL8 Q6UXH0 Angiopoietin-like protein 8 chr19 Not Cancer Driver No 1 hippie 17 26 6 6 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 intact, hippie 59 61 12 12 0
APRT APRT P07741 Adenine phosphoribosyltransferase chr16 Not Cancer Driver No 1 hippie 16 0 0 0 8
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 1 hippie 17 0 0 0 0
ARF5 ARF5 P84085 ADP-ribosylation factor 5 chr7 Not Cancer Driver No 1 hippie 22 11 2 2 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie 18 5 0 0 0
ARGLU1 ARGLU1 Q9NWB6 Arginine and glutamate-rich protein 1 chr13 Not Cancer Driver No 1 intact, hippie 37 246 33 33 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 Not Cancer Driver No 1 hippie 25 50 6 6 0
ARL6IP4_ENST00000543566 ARL6IP4 Q66PJ3-3 Isoform 3 of ADP-ribosylation factor-like protein 6-interacting protein 4 chr12 Not Cancer Driver No 1 hippie 16 386 15 15 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 77 511 56 56 0
ARNTL2 ARNTL2 Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 79 264 38 38 0
ARPP19_ENST00000567669 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 Not Cancer Driver No 1 intact, hippie 17 112 17 17 0
ASAP1 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie 183 584 108 108 0
ASAP2 ASAP2 O43150 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie 141 453 63 63 0
ASAP3 ASAP3 Q8TDY4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 chr1 Not Cancer Driver No 1 hippie 99 389 48 48 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 intact, hippie 469 225 39 39 41
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 60 85 8 8 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 intact, hippie 19 9 2 2 0
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 Census, Compendium Yes 1 intact, hippie 338 106 14 14 1
ATRIP ATRIP Q8WXE1 ATR-interacting protein chr3 Not Cancer Driver No 1 hippie 76 383 32 32 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 36 178 21 21 0
AVPI1 AVPI1 Q5T686 Arginine vasopressin-induced protein 1 chr10 Not Cancer Driver No 1 hippie 21 115 14 14 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 Census, Compendium Yes 4 intact, hippie 36 151 25 25 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 Census, Compendium Yes 1 hippie 24 72 5 5 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 1 hippie 69 83 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
C19orf12 C19orf12 Q9NSK7 Protein C19orf12 chr19 Not Cancer Driver No 1 intact, hippie 23 7 0 0 15
C19orf57_ENST00000586783 BRME1 Q0VDD7 Break repair meiotic recombinase recruitment factor 1 chr19 Not Cancer Driver No 1 intact 91 632 88 88 0
CAAP1 CAAP1 Q9H8G2 Caspase activity and apoptosis inhibitor 1 chr9 Not Cancer Driver No 1 intact, hippie 28 234 18 18 0
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 intact, hippie 287 368 52 52 1
CALB1 CALB1 P05937 Calbindin chr8 Not Cancer Driver No 1 intact, hippie 46 0 0 0 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 intact, hippie 42 212 19 19 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 intact, hippie 19 115 15 15 7
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 Not Cancer Driver No 1 intact, hippie 57 84 10 10 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 40 41 2 2 0
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 Not Cancer Driver No 1 hippie 94 474 40 40 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 Census, Compendium Yes 2 intact, hippie 303 530 140 140 5
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 1 intact, hippie 53 126 7 7 1
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 142 106 12 12 1
CCAR1 CCAR1 Q8IX12 Cell division cycle and apoptosis regulator protein 1 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 145 771 76 76 0
CCDC138 CCDC138 Q96M89 Coiled-coil domain-containing protein 138 chr2 Not Cancer Driver No 1 intact, hippie 76 202 25 25 0
CCDC14 CCDC14 Q49A88-6 Isoform 6 of Coiled-coil domain-containing protein 14 chr3 Not Cancer Driver No 1 intact, hippie 88 585 61 61 0
CCHCR1_ENST00000376266 CCHCR1 Q8TD31 Coiled-coil alpha-helical rod protein 1 chr6 Not Cancer Driver No 1 hippie 116 565 88 88 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 216 104 46 46 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 Not Cancer Driver No 1 hippie 39 56 6 6 2
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 7 intact, hippie, biogrid 52 214 31 31 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 Not Cancer Driver No 1 intact, hippie 155 1138 99 99 6
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 1 intact, hippie 52 52 5 5 3
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CENPF CENPF P49454 Centromere protein F chr1 Not Cancer Driver No 2 hippie, biogrid 387 2136 260 260 0
CETN3_ENST00000283122 CETN3 O15182 Centrin-3 chr5 Not Cancer Driver No 1 intact, hippie 13 19 1 1 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 Not Cancer Driver No 22 intact, hippie, biogrid 74 116 9 9 0
CIAPIN1 CIAPIN1 Q6FI81 Anamorsin chr16 Not Cancer Driver No 1 hippie, biogrid 27 119 8 8 0
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 intact, hippie 32 27 5 5 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 190 71 6 6 1
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 1 intact, hippie 31 21 1 1 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 Not Cancer Driver No 1 hippie 155 370 61 61 0
COMMD7 COMMD7 Q86VX2 COMM domain-containing protein 7 chr20 Not Cancer Driver No 1 hippie 29 21 0 0 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 intact, hippie 163 157 18 18 4
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 Not Cancer Driver No 1 intact, hippie 55 67 10 10 0
CPNE2_ENST00000535318 CPNE2 Q96FN4 Copine-2 chr16 Not Cancer Driver No 1 hippie 62 32 4 4 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 2 intact, hippie 412 1796 247 247 33
CSE1L CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie 109 32 5 5 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 intact, hippie 44 46 3 3 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 intact, hippie 59 132 16 16 2
CUEDC1_ENST00000407144 CUEDC1 Q9NWM3 CUE domain-containing protein 1 chr17 Not Cancer Driver No 1 intact, hippie 53 325 44 44 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
CWF19L2 CWF19L2 Q2TBE0 CWF19-like protein 2 chr11 Not Cancer Driver No 1 intact, hippie 119 615 83 83 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
D2HGDH D2HGDH Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 61 46 1 1 0
DAP3_ENST00000343043 DAP3 P51398 28S ribosomal protein S29, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 58 82 14 14 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 intact, hippie 193 114 11 11 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 intact 126 50 8 8 4
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 Census Yes 1 hippie 29 160 27 27 0
DDX19B DDX19B Q9UMR2 ATP-dependent RNA helicase DDX19B chr16 Not Cancer Driver No 1 hippie 44 113 9 9 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 133 301 47 47 18
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DNAJC8 DNAJC8 O75937 DnaJ homolog subfamily C member 8 chr1 Not Cancer Driver No 1 hippie 29 188 23 23 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 Not Cancer Driver No 1 hippie 262 454 53 53 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 intact, hippie 505 495 62 62 21
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 Not Cancer Driver No 1 hippie 46 208 20 20 0
ECPAS_ENST00000338205 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 intact, hippie 176 240 22 22 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie 109 100 14 14 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 intact, hippie 74 121 17 17 3
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 Not Cancer Driver No 1 hippie 35 206 8 8 2
EGLN2_ENST00000303961 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 Not Cancer Driver No 1 hippie 52 201 17 17 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF1AX EIF1AX P47813 Eukaryotic translation initiation factor 1A, X-chromosomal chrX Census, Compendium Yes 1 hippie 39 67 28 28 0
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 40 307 34 34 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 1 hippie 120 449 53 53 6
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 intact, hippie 182 140 24 24 0
EPPK1 EPPK1 P58107 Epiplakin chr8 Not Cancer Driver No 1 intact, hippie 417 1336 67 67 0
ERC1 ERC1 Q8IUD2 ELKS/Rab6-interacting/CAST family member 1 chr12 Census Yes 1 hippie 127 1013 119 119 0
ESYT1_ENST00000394048 ESYT1 Q9BSJ8 Extended synaptotagmin-1 chr12 Not Cancer Driver No 1 hippie 126 278 32 32 0
F10 F10 P00742 Coagulation factor X chr13 Not Cancer Driver No 1 hippie 98 120 24 24 26
F7 F7 P08709 Coagulation factor VII chr13 Not Cancer Driver No 1 intact, hippie 74 50 7 7 108
FADD FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 26 45 10 10 1
FAM83H FAM83H Q6ZRV2 Protein FAM83H chr8 Not Cancer Driver No 1 intact, hippie 151 893 95 95 1
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 intact, hippie 291 309 42 42 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 1 hippie 85 52 8 8 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 70 150 20 20 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 Census, Compendium Yes 1 hippie 200 64 27 27 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 hippie 253 259 41 41 13
FRMD8 FRMD8 Q9BZ67 FERM domain-containing protein 8 chr11 Not Cancer Driver No 1 hippie 50 119 12 12 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie 85 352 65 65 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 Not Cancer Driver No 1 hippie 13 20 2 2 0
GADD45GIP1 GADD45GIP1 Q8TAE8 Growth arrest and DNA damage-inducible proteins-interacting protein 1 chr19 Not Cancer Driver No 1 hippie 19 193 19 19 0
GART_ENST00000381815 GART P22102 Trifunctional purine biosynthetic protein adenosine-3 chr21 Not Cancer Driver No 1 intact, hippie 96 50 6 6 0
GCC1 GCC1 Q96CN9 GRIP and coiled-coil domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 118 508 69 69 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 intact, hippie 327 117 16 16 0
GEMIN2 GEMIN2 O14893 Gem-associated protein 2 chr14 Not Cancer Driver No 1 intact, hippie 39 99 6 6 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 intact, hippie 65 288 42 42 62
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 Not Cancer Driver No 1 hippie, biogrid 32 77 14 14 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 1 hippie 67 434 42 42 0
GIT2 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 1 hippie 83 492 47 47 0
GLO1 GLO1 Q04760 Lactoylglutathione lyase chr6 Not Cancer Driver No 1 hippie 24 46 7 7 0
GNGT1_ENST00000429473 GNGT1 P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 chr7 Not Cancer Driver No 1 hippie 14 25 4 4 0
GOLGA3_ENST00000450791 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 1 hippie 221 1272 189 189 0
GPKOW GPKOW Q92917 G-patch domain and KOW motifs-containing protein chrX Not Cancer Driver No 1 hippie 80 396 71 71 0
GRK4 GRK4 P32298 G protein-coupled receptor kinase 4 chr4 Not Cancer Driver No 1 intact, hippie 70 32 2 2 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 2 intact, hippie 56 146 13 13 0
GSTM3_ENST00000361066 GSTM3 P21266 Glutathione S-transferase Mu 3 chr1 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
GTF2E1 GTF2E1 P29083 General transcription factor IIE subunit 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 71 264 48 48 0
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 Not Cancer Driver No 1 intact, hippie 181 54 8 8 0
GYG2 GYG2 O15488 Glycogenin-2 chrX Not Cancer Driver No 1 intact, hippie 70 217 28 28 0
H1F0 H1-0 P07305 Histone H1.0 chr22 Not Cancer Driver No 1 intact 16 194 16 16 0
HBZ HBZ P02008 Hemoglobin subunit zeta chr16 Not Cancer Driver No 1 hippie 9 0 0 0 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 Not Cancer Driver No 1 hippie 103 446 94 94 0
HDDC2 HDDC2 Q7Z4H3 5'-deoxynucleotidase HDDC2 chr6 Not Cancer Driver No 1 hippie 26 74 7 7 0
HDLBP_ENST00000391976 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie 195 555 87 87 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HLA-DQA1 HLA-DQA1 A0A173ADG5 HLA class II histocompatibility antigen DQ alpha chain chr6 Not Cancer Driver No 1 hippie 29 5 0 0 0
HNRNPCL2 HNRNPCL2 B2RXH8 Heterogeneous nuclear ribonucleoprotein C-like 2 chr1 Not Cancer Driver No 1 hippie, biogrid 51 199 41 41 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 intact, hippie 77 504 45 45 0
HPCAL1_ENST00000381765 HPCAL1 P37235 Hippocalcin-like protein 1 chr2 Not Cancer Driver No 1 hippie 34 44 9 9 0
HPD HPD P32754 4-hydroxyphenylpyruvate dioxygenase chr12 Not Cancer Driver No 1 intact, hippie 61 40 9 9 3
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 4 intact, hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 4 intact, hippie, biogrid 100 254 43 43 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie 94 268 35 35 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 intact, hippie 119 141 28 28 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 intact, hippie 73 282 35 35 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 intact, hippie 112 235 27 27 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 67 283 26 26 2
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 hippie 336 666 69 69 2
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 Not Cancer Driver No 1 intact 130 28 4 4 4
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 Not Cancer Driver No 1 intact, hippie 20 17 6 6 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 Census, Compendium Yes 1 intact, hippie 14 34 4 4 0
IDE IDE P14735 Insulin-degrading enzyme chr10 Not Cancer Driver No 1 intact, hippie 90 96 8 8 0
IDH3A IDH3A P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 41 47 11 11 0
IFIT5 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 Not Cancer Driver No 1 hippie 43 19 0 0 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 27 intact, hippie, biogrid 106 211 31 31 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 hippie 108 76 13 13 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 6 intact, hippie 6 301 6 6 22
IL1B IL1B P01584 Interleukin-1 beta chr2 Not Cancer Driver No 1 intact, hippie 39 16 3 3 0
INHA INHA P05111 Inhibin alpha chain chr2 Not Cancer Driver No 3 hippie, biogrid 48 144 15 15 0
INO80E INO80E Q8NBZ0 INO80 complex subunit E chr16 Not Cancer Driver No 1 hippie 21 210 21 21 0
IPO7 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie 138 202 30 30 0
IPO9 IPO9 Q96P70 Importin-9 chr1 Not Cancer Driver No 1 hippie 145 102 22 22 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 2 intact, hippie 71 337 39 39 0
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 Not Cancer Driver No 1 hippie 68 116 20 20 2
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 intact, hippie 139 43 10 10 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 167 63 10 10 7
KANSL2 KANSL2 Q9H9L4 KAT8 regulatory NSL complex subunit 2 chr12 Not Cancer Driver No 1 intact, hippie 53 304 27 27 0
KCMF1 KCMF1 Q9P0J7 E3 ubiquitin-protein ligase KCMF1 chr2 Not Cancer Driver No 1 hippie 48 270 36 36 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 237 57 12 12 0
KIAA1671_ENST00000406486 KIAA1671 Q9BY89 Uncharacterized protein KIAA1671 chr22 Not Cancer Driver No 1 intact, hippie 14 1759 14 14 0
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 intact, hippie 122 586 67 67 0
KIR3DX1_ENST00000610811 KIR3DX1 A0A087WZE3 Putative killer cell immunoglobulin-like receptor-like protein KIR3DX1 chr19 Not Cancer Driver No 1 hippie 102 77 14 14 0
KLHL21 KLHL21 Q9UJP4 Kelch-like protein 21 chr1 Not Cancer Driver No 1 hippie 43 63 7 7 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 hippie 65 121 18 18 0
KPNA6 KPNA6 O60684 Importin subunit alpha-7 chr1 Not Cancer Driver No 1 hippie 70 97 17 17 0
KPNA7 KPNA7 A9QM74 Importin subunit alpha-8 chr7 Not Cancer Driver No 1 hippie 36 66 2 2 0
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 hippie 83 152 28 28 16
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 Not Cancer Driver No 1 hippie 86 160 31 31 18
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 intact, hippie 57 179 21 21 4
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie 65 221 37 37 3
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 1 intact 133 97 10 10 1
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LENG8 LENG8 Q96PV6 Leukocyte receptor cluster member 8 chr19 Not Cancer Driver No 1 intact, hippie 137 515 97 97 0
LGALS2 LGALS2 P05162 Galectin-2 chr22 Not Cancer Driver No 1 hippie 19 36 4 4 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 intact, hippie 88 687 81 81 0
LMCD1 LMCD1 Q9NZU5 LIM and cysteine-rich domains protein 1 chr3 Not Cancer Driver No 1 intact, hippie 63 110 24 24 0
LNX2 LNX2 Q8N448 Ligand of Numb protein X 2 chr13 Not Cancer Driver No 1 intact, hippie 85 277 35 35 0
LPXN_ENST00000395074 LPXN O60711 Leupaxin chr11 Not Cancer Driver No 1 intact, hippie 43 134 16 16 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 131 18 2 2 1
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 Not Cancer Driver No 3 hippie, biogrid 44 200 21 21 0
LUC7L2 LUC7L2 Q9Y383 Putative RNA-binding protein Luc7-like 2 chr7 Not Cancer Driver No 1 intact, hippie 59 262 45 45 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
LZIC_ENST00000377213 LZIC Q8WZA0 Protein LZIC chr1 Not Cancer Driver No 1 intact, hippie 13 65 5 5 0
LZTR1_ENST00000646124 LZTR1 Q8N653 Leucine-zipper-like transcriptional regulator 1 chr22 Census, Compendium Yes 1 intact, hippie 160 106 18 18 26
MACROD1 MACROD1 Q9BQ69 ADP-ribose glycohydrolase MACROD1 chr11 Not Cancer Driver No 1 hippie 24 45 1 1 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 Census, Compendium Yes 1 hippie 75 139 12 12 1
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 7 intact, hippie, biogrid 94 543 52 52 0
MAP3K2_ENST00000344908 MAP3K2 Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 chr2 Not Cancer Driver No 1 hippie 75 313 47 47 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact, hippie 104 333 66 66 6
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie 26 109 11 11 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 Not Cancer Driver No 1 intact 91 151 16 16 8
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie 70 411 58 58 0
MCM10 MCM10 Q7L590 Protein MCM10 homolog chr10 Not Cancer Driver No 1 intact, hippie 152 535 102 102 1
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 2 intact, hippie 101 128 22 22 0
MED7 MED7 O43513 Mediator of RNA polymerase II transcription subunit 7 chr5 Not Cancer Driver No 1 intact, hippie 32 132 19 19 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 Not Cancer Driver No 1 hippie 175 159 31 31 3
MIB2_ENST00000504599 MIB2 Q96AX9 E3 ubiquitin-protein ligase MIB2 chr1 Not Cancer Driver No 1 hippie 88 307 31 31 0
MPHOSPH9_ENST00000541076 MPHOSPH9 A0A8I5IG87 M-phase phosphoprotein 9 chr12 Not Cancer Driver No 1 intact, hippie 125 943 92 92 0
MPP5 PALS1 Q8N3R9 Protein PALS1 chr14 Not Cancer Driver No 1 intact 70 337 33 33 0
MPRIP_ENST00000341712 MPRIP Q6WCQ1 Myosin phosphatase Rho-interacting protein chr17 Not Cancer Driver No 1 hippie 118 735 95 95 0
MRFAP1L1 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 1 intact, hippie 92 37 4 4 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 Not Cancer Driver No 1 hippie 100 211 20 20 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 Census, Compendium Yes 1 hippie 379 296 37 37 18
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
MUC13 MUC13 Q9H3R2 Mucin-13 chr3 Not Cancer Driver No 1 hippie 86 231 37 37 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 Census Yes 1 hippie 40 1050 19 19 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 Census, Compendium Yes 1 hippie 37 47 1 1 2
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 Not Cancer Driver No 1 intact, hippie 258 1134 136 136 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 intact, hippie 19 70 13 13 0
MYL5 MYL5 Q02045 Myosin light chain 5 chr4 Not Cancer Driver No 1 intact, hippie 21 44 6 6 0
MYL6_ENST00000548293 MYL6 P60660 Myosin light polypeptide 6 chr12 Not Cancer Driver No 1 intact, hippie 13 17 1 1 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 intact, hippie 110 66 11 11 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 intact, hippie 126 61 6 6 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 intact, hippie 176 342 41 41 3
MZT2A MZT2A Q6P582 Mitotic-spindle organizing protein 2A chr2 Not Cancer Driver No 1 hippie 16 114 14 14 0
NAP1L5 NAP1L5 Q96NT1 Nucleosome assembly protein 1-like 5 chr4 Not Cancer Driver No 1 intact, hippie 23 152 18 18 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 Not Cancer Driver No 1 intact, hippie 176 1231 160 160 0
NECAB3 NECAB3 Q96P71 N-terminal EF-hand calcium-binding protein 3 chr20 Not Cancer Driver No 1 hippie 39 169 17 17 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEFM NEFM P07197 Neurofilament medium polypeptide chr8 Not Cancer Driver No 1 hippie, biogrid 182 767 147 147 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 3 intact, hippie 104 344 38 38 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact, hippie 86 510 46 46 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 5 intact, hippie 37 102 9 9 1
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 Not Cancer Driver No 2 intact, hippie, biogrid 42 223 29 29 0
NFKBIE NFKBIE O00221 NF-kappa-B inhibitor epsilon chr6 Census, Compendium Yes 1 hippie 41 284 16 16 0
NHP2 NHP2 Q9NX24 H/ACA ribonucleoprotein complex subunit 2 chr5 Not Cancer Driver No 1 hippie 26 20 4 4 2
NLRP2 NLRP2 Q9NX02 NACHT, LRR and PYD domains-containing protein 2 chr19 Not Cancer Driver No 1 hippie 257 60 15 15 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 Not Cancer Driver No 1 hippie 158 94 13 13 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 Not Cancer Driver No 1 hippie 169 40 4 4 15
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 Not Cancer Driver No 1 intact, hippie 9 11 1 1 0
NRBF2 NRBF2 Q96F24 Nuclear receptor-binding factor 2 chr10 Not Cancer Driver No 1 intact, hippie 34 224 25 25 0
NSFL1C_ENST00000216879 NSFL1C Q9UNZ2 NSFL1 cofactor p47 chr20 Not Cancer Driver No 1 hippie 56 266 39 39 0
NTMT1_ENST00000613644 NTMT1 Q9BV86 N-terminal Xaa-Pro-Lys N-methyltransferase 1 chr9 Not Cancer Driver No 1 hippie 27 1 0 0 0
NTPCR NTPCR Q9BSD7 Cancer-related nucleoside-triphosphatase chr1 Not Cancer Driver No 1 hippie 30 31 2 2 0
NUMBL NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 1 hippie 42 467 23 23 0
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie 154 221 19 19 1
NUP43 NUP43 Q8NFH3 Nucleoporin Nup43 chr6 Not Cancer Driver No 1 intact, hippie 47 103 9 9 0
ODAM ODAM A1E959 Odontogenic ameloblast-associated protein chr4 Not Cancer Driver No 1 intact, hippie 51 140 18 18 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OSBPL10 OSBPL10 Q9BXB5 Oxysterol-binding protein-related protein 10 chr3 Not Cancer Driver No 1 intact, hippie 113 366 63 63 0
OSGIN1 OSGIN1 Q9UJX0 Oxidative stress-induced growth inhibitor 1 chr16 Not Cancer Driver No 1 hippie 57 79 10 10 0
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 1 intact, hippie 45 128 18 18 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 intact, hippie 119 320 34 34 0
PARP10_ENST00000313028 PARP10 Q53GL7 Protein mono-ADP-ribosyltransferase PARP10 chr8 Not Cancer Driver No 1 hippie 122 552 68 68 0
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 Not Cancer Driver No 1 hippie 221 301 57 57 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 100 605 86 86 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 Not Cancer Driver No 1 hippie 142 110 28 28 1
PCSK5 PCSK5 Q92824 Proprotein convertase subtilisin/kexin type 5 chr9 Not Cancer Driver No 1 hippie 319 168 25 25 0
PDCL PDCL Q13371 Phosducin-like protein chr9 Not Cancer Driver No 1 intact, hippie 33 146 13 13 0
PFDN5 PFDN5 Q99471 Prefoldin subunit 5 chr12 Not Cancer Driver No 1 hippie 18 3 0 0 0
PHF7 PHF7 Q9BWX1 PHD finger protein 7 chr3 Not Cancer Driver No 1 intact, hippie 44 62 5 5 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie 58 142 23 23 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 93 137 14 14 0
PIM2 PIM2 Q9P1W9 Serine/threonine-protein kinase pim-2 chrX Not Cancer Driver No 1 hippie 43 47 10 10 0
PLBD1 PLBD1 Q6P4A8 Phospholipase B-like 1 chr12 Not Cancer Driver No 1 hippie, biogrid 71 21 2 2 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHB2_ENST00000409279 PLEKHB2 Q96CS7 Pleckstrin homology domain-containing family B member 2 chr2 Not Cancer Driver No 1 intact, hippie 40 42 11 11 0
PLEKHJ1_ENST00000589097 PLEKHJ1 Q9NW61 Pleckstrin homology domain-containing family J member 1 chr19 Not Cancer Driver No 1 intact, hippie 10 9 0 0 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 Not Cancer Driver No 1 intact, hippie 59 369 37 37 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
PNMA8A PNMA8A Q86V59 Paraneoplastic antigen-like protein 8A chr19 Not Cancer Driver No 1 intact, hippie 82 290 55 55 0
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 intact, hippie 39 85 6 6 0
POLR2B_ENST00000314595 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 1 intact, hippie 166 173 25 25 0
POLR2D POLR2D O15514 DNA-directed RNA polymerase II subunit RPB4 chr2 Not Cancer Driver No 1 intact, hippie 13 54 2 2 0
POLR2E POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 1 intact, hippie 31 36 3 3 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 intact, hippie 155 113 17 17 15
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie 164 865 126 126 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie 65 243 31 31 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 intact, hippie 26 23 4 4 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 2 intact, hippie 41 12 1 1 8
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 hippie 72 17 1 1 0
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 Not Cancer Driver No 1 hippie 41 0 0 0 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 205 148 40 40 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 Not Cancer Driver No 1 hippie 107 170 26 26 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie 110 120 16 16 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 Not Cancer Driver No 1 hippie 147 28 9 9 0
PRKD3 PRKD3 O94806 Serine/threonine-protein kinase D3 chr2 Not Cancer Driver No 1 intact, hippie 125 183 20 20 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 intact, hippie 538 421 61 61 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPF18 PRPF18 Q99633 Pre-mRNA-splicing factor 18 chr10 Not Cancer Driver No 1 hippie 52 93 18 18 0
PSG11 PSG11 Q9UQ72 Pregnancy-specific beta-1-glycoprotein 11 chr19 Not Cancer Driver No 1 hippie, biogrid 115 34 9 9 0
PSG1_ENST00000436291 PSG1 P11464 Pregnancy-specific beta-1-glycoprotein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 168 78 29 29 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 intact, hippie 27 30 5 5 0
PSMB5 PSMB5 P28074 Proteasome subunit beta type-5 chr14 Not Cancer Driver No 1 intact, hippie 39 9 0 0 0
PSMB8 PSMB8 P28062 Proteasome subunit beta type-8 chr6 Not Cancer Driver No 1 hippie 43 62 7 7 3
PSMD13_ENST00000532097 PSMD13 Q9UNM6 26S proteasome non-ATPase regulatory subunit 13 chr11 Not Cancer Driver No 1 intact, hippie 30 13 3 3 0
PTS PTS Q03393 6-pyruvoyl tetrahydrobiopterin synthase chr11 Not Cancer Driver No 1 hippie, biogrid 9 22 1 1 24
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 Not Cancer Driver No 1 hippie 16 39 4 4 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie 31 43 4 4 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 Not Cancer Driver No 1 hippie 26 39 3 3 2
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 Not Cancer Driver No 1 hippie 145 1118 133 133 0
RAB11FIP3 RAB11FIP3 O75154 Rab11 family-interacting protein 3 chr16 Not Cancer Driver No 1 hippie 51 605 33 33 0
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 Not Cancer Driver No 1 hippie 37 26 3 3 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie 74 255 27 27 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RADIL RADIL Q96JH8 Ras-associating and dilute domain-containing protein chr7 Not Cancer Driver No 1 hippie 173 381 62 62 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 Not Cancer Driver No 1 hippie 65 381 46 46 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 1 intact 72 41 3 3 2
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 Not Cancer Driver No 1 intact, hippie 99 750 76 76 1
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 Not Cancer Driver No 5 intact, hippie 52 140 14 14 2
RBM26_ENST00000438737 RBM26 Q5T8P6 RNA-binding protein 26 chr13 Not Cancer Driver No 1 intact, hippie 117 834 100 100 0
RBM34 RBM34 P42696 RNA-binding protein 34 chr1 Not Cancer Driver No 1 intact, hippie 50 267 34 34 0
RBM8A_ENST00000632555 RBM8A Q9Y5S9 RNA-binding protein 8A chr1 Not Cancer Driver No 1 intact, hippie 35 135 32 32 0
RBP1_ENST00000619087 RBP1 P09455 Retinol-binding protein 1 chr3 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 intact, hippie 208 105 12 12 139
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 6 intact, hippie 82 277 39 39 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 intact, hippie 63 143 20 20 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 Not Cancer Driver No 1 hippie 30 112 7 7 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RNF7 RNF7 Q9UBF6 RING-box protein 2 chr3 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie 203 299 71 71 5
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 Census Yes 1 hippie 498 191 55 55 0
RPAP3 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 intact, hippie 59 334 37 37 0
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 Not Cancer Driver No 1 intact, hippie 27 12 1 1 1
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 intact, hippie 14 29 4 4 0
RPL41 RPL41 P62945 60S ribosomal protein L41 chr12 Not Cancer Driver No 1 intact, hippie 4 25 4 4 0
RPLP0_ENST00000228306 RPLP0 P05388 60S acidic ribosomal protein P0 chr12 Not Cancer Driver No 1 intact, hippie 44 36 4 4 0
RPLP2_ENST00000530797 RPLP2 P05387 60S acidic ribosomal protein P2 chr11 Not Cancer Driver No 1 intact, hippie 12 59 5 5 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 intact, hippie 50 69 3 3 0
RPS10_ENST00000467531 RPS10 P46783 40S ribosomal protein S10 chr6 Not Cancer Driver No 1 intact, hippie 25 100 19 19 0
RPS12 RPS12 P25398 40S ribosomal protein S12 chr6 Not Cancer Driver No 1 hippie 17 0 0 0 0
RPS14_ENST00000521466 RPS14 P62263 40S ribosomal protein S14 chr5 Not Cancer Driver No 1 intact, hippie 14 96 13 13 0
RPS15A_ENST00000565420 RPS15A P62244 40S ribosomal protein S15a chr16 Not Cancer Driver No 1 intact, hippie 6 4 0 0 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 Not Cancer Driver No 1 intact, hippie 16 14 1 1 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 Not Cancer Driver No 1 intact, hippie 18 53 8 8 0
RPS27 RPS27 P42677 40S ribosomal protein S27 chr1 Not Cancer Driver No 1 intact, hippie 10 29 7 7 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 Not Cancer Driver No 1 intact, hippie 4 22 2 2 0
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 1 intact, hippie 21 85 5 5 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 Not Cancer Driver No 1 intact, hippie 22 48 4 4 0
RPS5_ENST00000601521 RPS5 P46782 40S ribosomal protein S5 chr19 Not Cancer Driver No 1 intact, hippie 38 40 8 8 0
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 54 194 16 16 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 Not Cancer Driver No 1 hippie 147 403 57 57 0
RUSC1 RUSC1 Q9BVN2 AP-4 complex accessory subunit RUSC1 chr1 Not Cancer Driver No 1 intact, hippie 99 640 69 69 0
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 6 2 2 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie 174 1071 153 153 7
SCLT1 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 intact, hippie 98 398 61 61 0
SDCCAG8 SDCCAG8 Q86SQ7 Serologically defined colon cancer antigen 8 chr1 Not Cancer Driver No 2 hippie, biogrid 110 487 73 73 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 Not Cancer Driver No 1 hippie, biogrid 111 149 27 27 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 Not Cancer Driver No 1 hippie 73 285 38 38 0
SEPT9 SEPTIN9 Q9UHD8 Septin-9 chr17 Not Cancer Driver No 1 intact 84 332 50 50 2
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie 35 221 26 26 2
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 31 29 1 1 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 Census, Compendium Yes 1 intact, hippie 58 86 16 16 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 4 intact, hippie 34 237 16 16 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 Census Yes 1 intact, hippie 68 470 52 52 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie 52 52 6 6 0
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 intact, hippie 75 436 63 63 0
SMC2 SMC2 O95347 Structural maintenance of chromosomes protein 2 chr9 Not Cancer Driver No 1 hippie 145 573 88 88 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 Not Cancer Driver No 1 intact, hippie 175 539 55 55 0
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 hippie 2 181 2 2 0
SNURF SNURF Q9Y675 SNRPN upstream reading frame protein chr15 Not Cancer Driver No 1 intact 19 67 19 19 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 Not Cancer Driver No 1 hippie 70 235 39 39 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 Not Cancer Driver No 1 hippie, biogrid 317 877 126 126 2
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 intact, hippie 54 267 32 32 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie 73 329 32 32 0
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 intact, hippie 82 265 31 31 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 intact, hippie 42 170 15 15 0
STX11 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 1 intact, hippie 71 48 7 7 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 3 intact, hippie 10 76 7 7 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 165 572 87 87 0
SURF6 SURF6 O75683 Surfeit locus protein 6 chr9 Not Cancer Driver No 1 hippie, biogrid 58 337 56 56 0
SYNC SYNC Q9H7C4 Syncoilin chr1 Not Cancer Driver No 2 hippie, biogrid 30 358 22 22 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 Not Cancer Driver No 1 hippie, biogrid 153 830 90 90 2
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 Not Cancer Driver No 1 hippie 104 103 36 36 5
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 2 intact, hippie 81 232 34 34 0
TAB2_ENST00000637181 TAB2 Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 chr6 Not Cancer Driver No 1 intact, hippie 87 573 73 73 2
TAB3 TAB3 Q8N5C8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 chrX Not Cancer Driver No 1 hippie 130 654 116 116 0
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 Not Cancer Driver No 1 hippie 40 258 31 31 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 5 intact, hippie, biogrid 42 302 26 26 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 Not Cancer Driver No 1 hippie 45 203 22 22 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 Not Cancer Driver No 1 hippie 51 1 0 0 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 Not Cancer Driver No 1 intact, hippie 156 60 9 9 11
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 5 intact, hippie, biogrid 101 42 5 5 12
TCEANC_ENST00000380600 TCEANC Q8N8B7 Transcription elongation factor A N-terminal and central domain-containing protein chrX Not Cancer Driver No 1 intact, hippie 38 138 12 12 0
TCP10L TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 1 intact, hippie 32 213 32 32 0
TCP11L1_ENST00000432887 TCP11L1 Q9NUJ3 T-complex protein 11-like protein 1 chr11 Not Cancer Driver No 1 intact, hippie 59 74 8 8 0
TCP11_ENST00000512012 TCP11 Q8WWU5 T-complex protein 11 homolog chr6 Not Cancer Driver No 1 intact, hippie 78 112 13 13 0
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie 91 57 15 15 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 Not Cancer Driver No 1 intact, hippie 219 126 22 22 10
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie 89 80 6 6 1
TIMM50_ENST00000607714 TIMM50 Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 chr19 Not Cancer Driver No 1 intact, hippie 39 75 7 7 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 Not Cancer Driver No 1 hippie 123 0 0 0 1
TMA16 TMA16 Q96EY4 Translation machinery-associated protein 16 chr4 Not Cancer Driver No 1 intact, hippie 25 112 10 10 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 4 intact, hippie 24 45 3 3 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 Census, Compendium Yes 1 hippie 98 231 33 33 1
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 2 intact, hippie 58 111 15 15 12
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 3 intact, hippie 85 625 83 83 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 3 intact, hippie 43 316 36 36 0
TNPO2 TNPO2 O14787 Transportin-2 chr19 Not Cancer Driver No 1 hippie 99 76 10 10 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 1 intact, hippie 284 1830 265 265 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 1 intact, hippie 205 1735 195 195 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 Not Cancer Driver No 3 hippie, biogrid 33 234 29 29 8
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 intact, hippie 17 43 6 6 0
TPX2 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 Not Cancer Driver No 1 hippie 92 695 86 86 0
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 Not Cancer Driver No 1 intact, hippie 26 74 5 5 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 hippie 51 63 9 9 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 hippie 63 4 1 1 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 Not Cancer Driver No 1 hippie 59 410 39 39 2
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 1 hippie 61 101 9 9 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 Not Cancer Driver No 1 hippie 53 1 0 0 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM22 TRIM22 Q8IYM9 E3 ubiquitin-protein ligase TRIM22 chr11 Not Cancer Driver No 1 hippie 93 26 1 1 0
TRIM23 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 Not Cancer Driver No 1 hippie 91 39 2 2 0
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 Not Cancer Driver No 1 hippie 67 153 16 16 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 intact, hippie 87 430 41 41 0
TRIM29 TRIM29 Q14134 Tripartite motif-containing protein 29 chr11 Not Cancer Driver No 1 hippie 121 351 72 72 0
TRIM31 TRIM31 Q9BZY9 E3 ubiquitin-protein ligase TRIM31 chr6 Not Cancer Driver No 1 intact, hippie 55 152 21 21 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRIM40_ENST00000376724 TRIM40 Q6P9F5 E3 ubiquitin ligase TRIM40 chr6 Not Cancer Driver No 1 hippie 44 84 12 12 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 Not Cancer Driver No 1 intact, hippie 69 385 38 38 0
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 Not Cancer Driver No 1 hippie 71 77 11 11 0
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 Not Cancer Driver No 1 hippie 386 2196 370 370 1
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 intact, hippie 62 268 19 19 0
TRPC4AP TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 Not Cancer Driver No 1 hippie 84 70 7 7 0
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 Not Cancer Driver No 1 intact, hippie 27 16 0 0 0
TTYH2 TTYH2 Q9BSA4 Protein tweety homolog 2 chr17 Not Cancer Driver No 1 intact, hippie 63 68 19 19 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 59 52 11 11 8
TUBA3C TUBA3C P0DPH7 Tubulin alpha-3C chain chr13 Not Cancer Driver No 1 intact 185 36 14 14 0
TUBA3D TUBA3D P0DPH8 Tubulin alpha-3D chain chr2 Not Cancer Driver No 1 hippie 74 36 4 4 0
TUBA4B TUBA4B Q9H853 Putative tubulin-like protein alpha-4B chr2 Not Cancer Driver No 1 intact, hippie 43 27 3 3 0
TUBA8 TUBA8 Q9NY65 Tubulin alpha-8 chain chr22 Not Cancer Driver No 1 intact, hippie 50 32 0 0 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 40 63 11 11 5
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 intact, hippie 91 61 16 16 2
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie 51 44 10 10 3
TXLNA_ENST00000373610 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 intact, hippie 68 481 59 59 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 Not Cancer Driver No 1 intact, hippie 119 197 17 17 0
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 Not Cancer Driver No 1 hippie 101 27 8 8 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 2 intact, hippie, biogrid 20 102 8 8 0
UBC UBC P0CG48 Polyubiquitin-C chr12 Not Cancer Driver No 3 intact 97 312 53 53 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 Not Cancer Driver No 1 hippie 21 13 4 4 0
UBE2D4 UBE2D4 Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 chr7 Not Cancer Driver No 1 hippie 13 21 1 1 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UBXN6 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 64 132 26 26 0
USO1_ENST00000514213 USO1 O60763 General vesicular transport factor p115 chr4 Not Cancer Driver No 1 intact, hippie 78 368 28 28 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 Not Cancer Driver No 1 intact, hippie 92 425 49 49 0
USP18 USP18 Q9UMW8 Ubl carboxyl-terminal hydrolase 18 chr22 Not Cancer Driver No 1 intact, hippie 34 29 8 8 0
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 Not Cancer Driver No 1 hippie 88 213 39 39 0
USP32 USP32 Q8NFA0 Ubiquitin carboxyl-terminal hydrolase 32 chr17 Not Cancer Driver No 1 hippie, biogrid 182 401 43 43 0
USP54 USP54 Q70EL1 Inactive ubiquitin carboxyl-terminal hydrolase 54 chr10 Not Cancer Driver No 1 hippie 186 1268 143 143 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 hippie 170 215 45 45 0
UTP20 UTP20 O75691 Small subunit processome component 20 homolog chr12 Not Cancer Driver No 1 intact, hippie 324 314 35 35 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie 11 17 1 1 0
VARS VARS1 P26640 Valine--tRNA ligase chr6 Not Cancer Driver No 1 intact 145 251 26 26 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 intact, hippie 84 316 57 57 1
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie 30 35 3 3 0
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 intact, hippie 139 431 75 75 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie 112 64 7 7 0
XPO7 XPO7 Q9UIA9 Exportin-7 chr8 Not Cancer Driver No 1 hippie 132 59 8 8 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 hippie 87 118 11 11 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact, hippie 30 81 10 10 0
ZBTB3 ZBTB3 Q9H5J0 Zinc finger and BTB domain-containing protein 3 chr11 Not Cancer Driver No 1 intact, hippie 68 352 35 35 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 Not Cancer Driver No 1 hippie 90 396 44 44 0
ZFAND5 ZFAND5 O76080 AN1-type zinc finger protein 5 chr9 Not Cancer Driver No 1 hippie 31 162 19 19 0
ZNF587 ZNF587 Q96SQ5 Zinc finger protein 587 chr19 Not Cancer Driver No 1 intact, hippie 81 155 22 22 0
ZNF835 ZNF835 Q9Y2P0 Zinc finger protein 835 chr19 Not Cancer Driver No 1 intact, hippie 202 228 91 91 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 Not Cancer Driver No 2 hippie, biogrid 38 291 27 27 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 87 158 25 25 0