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IGSF3_ENST00000369486 ,IGSF3 ,O75054
  • Number of Interaction partner in intact: 21
  • Number of Interaction partner in biogrid: 31
  • Number of Interaction partner in hippie: 60
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 1 hippie, biogrid 50 39 4 4 17
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 46 85 7 7 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 Not Cancer Driver No 1 hippie, biogrid 38 55 9 9 0
C11orf52 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 15 108 12 12 0
CACNG1 CACNG1 Q06432 Voltage-dependent calcium channel gamma-1 subunit chr17 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CD9 CD9 P21926 CD9 antigen chr12 Not Cancer Driver No 1 intact, hippie 22 0 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDR2 CDR2 Q01850 Cerebellar degeneration-related protein 2 chr16 Not Cancer Driver No 2 hippie, biogrid 50 287 26 26 0
CEACAM8 CEACAM8 P31997 Carcinoembryonic antigen-related cell adhesion molecule 8 chr19 Not Cancer Driver No 1 hippie, biogrid 75 136 23 23 0
CGB3 CGB3 A0A0F7RQP8 Chorionic gonadotropin beta subunit 3 chr19 Not Cancer Driver No 1 hippie 8 41 3 3 0
CGB5 CGB3 A0A0F7RQP8 Chorionic gonadotropin beta subunit 3 chr19 Not Cancer Driver No 1 hippie 19 41 7 7 0
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 hippie, biogrid 9 0 0 0 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 2 hippie, biogrid 31 27 3 3 0
GALNT10 GALNT10 Q86SR1 Polypeptide N-acetylgalactosaminyltransferase 10 chr5 Not Cancer Driver No 1 hippie, biogrid 85 95 17 17 0
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 74 33 6 6 19
GP5 GP5 P40197 Platelet glycoprotein V chr3 Not Cancer Driver No 1 hippie, biogrid 81 57 5 5 0
HDLBP_ENST00000391976 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie 195 555 87 87 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 31 14 14 0
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 Not Cancer Driver No 1 intact 47 77 30 30 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 21 31 7 7 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 103 49 11 11 12
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 65 21 4 4 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 hippie, biogrid 788 7 2 2 27
KTN1 KTN1 Q86UP2 Kinectin chr14 Census Yes 1 hippie, biogrid 138 964 102 102 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 3 hippie, biogrid 54 65 16 16 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 Not Cancer Driver No 1 hippie, biogrid 73 0 0 0 0
NAALADL2 NAALADL2 Q58DX5 Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 162 207 46 46 0
NEURL4 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 217 751 119 119 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie, biogrid 50 49 3 3 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 52 19 2 2 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 34 63 6 6 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 2 intact, hippie, biogrid 68 99 17 17 0
ST14 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 Not Cancer Driver No 1 hippie, biogrid 106 47 5 5 1
TMPRSS13_ENST00000445164 TMPRSS13 Q9BYE2 Transmembrane protease serine 13 chr11 Not Cancer Driver No 1 hippie, biogrid 122 199 75 75 0
TSPAN14_ENST00000372156 TSPAN14 Q8NG11 Tetraspanin-14 chr10 Not Cancer Driver No 1 intact, hippie 38 0 0 0 0
TSPAN15 TSPAN15 O95858 Tetraspanin-15 chr10 Not Cancer Driver No 1 intact, hippie 29 0 0 0 0
TSPAN5 TSPAN5 P62079 Tetraspanin-5 chr4 Not Cancer Driver No 1 intact, hippie 49 0 0 0 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0