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ICMT ,ICMT ,O60725
  • Uniprot Accession= O60725
  • Ensembl Transcript= ENST00000343813.9
  • Uniprot Name= ICMT
  • Name= Protein-S-isoprenylcysteine O-methyltransferase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 18
  • Number of Interaction partner in hippie: 51
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
AQP6_ENST00000315520 AQP6 Q13520 Aquaporin-6 chr12 Not Cancer Driver No 1 intact, hippie 48 22 4 4 0
ARL13B ARL13B Q3SXY8 ADP-ribosylation factor-like protein 13B chr3 Not Cancer Driver No 1 intact, hippie 62 251 40 40 3
ARMC8_ENST00000469044 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 71 7 0 0 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CLN6 CLN6 Q9NWW5 Ceroid-lipofuscinosis neuronal protein 6 chr15 Not Cancer Driver No 1 intact, hippie 28 13 0 0 24
CLUAP1_ENST00000576634 CLUAP1 Q96AJ1 Clusterin-associated protein 1 chr16 Not Cancer Driver No 1 hippie 48 203 22 22 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 Not Cancer Driver No 1 hippie 31 7 0 0 0
DUSP28_ENST00000343217 DUSP28 Q4G0W2 Dual specificity phosphatase 28 chr2 Not Cancer Driver No 1 hippie 11 55 4 4 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX Not Cancer Driver No 1 intact, hippie 51 327 34 34 0
FAM120C FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 162 508 77 77 0
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
GCA GCA P28676 Grancalcin chr2 Not Cancer Driver No 2 intact, hippie, biogrid 30 29 1 1 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 97 0 0 0 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 Not Cancer Driver No 1 intact, hippie 21 12 2 2 5
KCNJ6_ENST00000645093 KCNJ6 P48051 G protein-activated inward rectifier potassium channel 2 chr21 Not Cancer Driver No 1 intact, hippie 106 75 13 13 1
LRRC25_ENST00000595840 LRRC25 Q8N386 Leucine-rich repeat-containing protein 25 chr19 Not Cancer Driver No 1 hippie, biogrid 40 89 14 14 0
MFSD4A MFSD4A Q8N468 Major facilitator superfamily domain-containing protein 4A chr1 Not Cancer Driver No 1 hippie 56 29 3 3 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 Census Yes 1 intact, hippie 40 1050 19 19 0
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 Not Cancer Driver No 1 hippie, biogrid 42 43 3 3 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 Not Cancer Driver No 2 hippie, biogrid 69 208 29 29 0
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 Not Cancer Driver No 1 intact, hippie, biogrid 102 42 14 14 16
PDZK1IP1_ENST00000371885 PDZK1IP1 Q13113 PDZK1-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 22 21 0 0 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PPM1E PPM1E Q8WY54 Protein phosphatase 1E chr17 Not Cancer Driver No 1 intact, hippie, biogrid 114 384 53 53 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 205 148 40 40 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 34 49 10 10 0
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 19 201 11 11 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 Not Cancer Driver No 1 hippie 58 344 24 24 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 50 69 3 3 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 51 13 2 2 48
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 Not Cancer Driver No 2 hippie, biogrid 59 64 9 9 0
TMEM41B_ENST00000611268 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 19 47 3 3 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 hippie 82 87 10 10 3
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 41 10 2 2 0
VIPR2 VIPR2 P41587 Vasoactive intestinal polypeptide receptor 2 chr7 Not Cancer Driver No 1 hippie, biogrid 74 0 0 0 0