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IBA57 ,IBA57 ,Q5T440
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 57
  • Number of Interaction partner in hippie: 80
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 123 203 25 25 5
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 69 28 5 5 12
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 23 33 3 3 0
ARHGAP22_ENST00000249601 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 Not Cancer Driver No 2 hippie, biogrid 138 449 90 90 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AUH AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 34 29 0 0 1
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 1 hippie 18 104 8 8 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 6 6 2
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 22 83 9 9 3
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 2 hippie, biogrid 50 13 2 2 0
CZIB CZIB Q9NWV4 CXXC motif containing zinc binding protein chr1 Not Cancer Driver No 1 hippie 19 2 1 1 0
DNAJC19 DNAJC19 Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 chr3 Not Cancer Driver No 1 hippie, biogrid 19 27 6 6 0
ECHDC2 ECHDC2 Q86YB7 Enoyl-CoA hydratase domain-containing protein 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 43 10 1 1 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EIF4A1 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 2 hippie, biogrid 48 35 7 7 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 74 30 2 2 0
GFM1_ENST00000486715 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 74 79 7 7 4
GFM2_ENST00000509430 GFM2 Q969S9 Ribosome-releasing factor 2, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 75 100 10 10 2
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 49 147 20 20 0
GTF2E2 GTF2E2 P29084 Transcription initiation factor IIE subunit beta chr8 Not Cancer Driver No 2 hippie, biogrid 34 130 16 16 2
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 2 hippie, biogrid 10 29 2 2 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 36 25 6 6 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 61 82 6 6 2
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
IMPDH1_ENST00000626419 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 Not Cancer Driver No 2 hippie, biogrid 75 13 1 1 7
ISCA1 ISCA1 Q9BUE6 Iron-sulfur cluster assembly 1 homolog, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 8 11 1 1 0
ISCA2 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 Not Cancer Driver No 2 hippie, biogrid 13 38 3 3 1
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 99 175 15 15 10
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
LUC7L LUC7L Q9NQ29 Putative RNA-binding protein Luc7-like 1 chr16 Not Cancer Driver No 2 hippie, biogrid 50 254 41 41 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
METTL15 METTL15 A6NJ78 12S rRNA N4-methylcytidine (m4C) methyltransferase chr11 Not Cancer Driver No 1 hippie, biogrid 46 92 14 14 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MINDY3 MINDY3 Q9H8M7 Ubiquitin carboxyl-terminal hydrolase MINDY-3 chr10 Not Cancer Driver No 1 hippie 73 17 2 2 0
MINOS1 MICOS10 Q5TGZ0 MICOS complex subunit MIC10 chr1 Not Cancer Driver No 1 hippie 5 0 0 0 0
MRPL11 MRPL11 Q9Y3B7 39S ribosomal protein L11, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 25 12 1 1 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 Not Cancer Driver No 1 hippie 28 105 13 13 0
MRRF MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 3 hippie, biogrid 23 118 9 9 0
MTERF3 MTERF3 Q96E29 Transcription termination factor 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 53 62 5 5 0
MTG1 MTG1 Q9BT17 Mitochondrial ribosome-associated GTPase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 43 16 3 3 0
MTIF2_ENST00000403721 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 101 112 9 9 0
MTIF3_ENST00000381120 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 26 180 19 19 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
MTRF1L MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 31 183 12 12 0
NIT1 NIT1 Q86X76 Deaminated glutathione amidase chr1 Not Cancer Driver No 1 hippie, biogrid 41 18 3 3 0
NME4 NME4 O00746 Nucleoside diphosphate kinase, mitochondrial chr16 Not Cancer Driver No 1 hippie 13 41 4 4 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie, biogrid 101 349 64 64 0
OXLD1 OXLD1 Q5BKU9 Oxidoreductase-like domain-containing protein 1 chr17 Not Cancer Driver No 2 hippie, biogrid 23 84 17 17 0
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 hippie 49 28 5 5 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 52 50 10 10 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PMPCB PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 55 22 3 3 5
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 Not Cancer Driver No 1 hippie, biogrid 25 43 4 4 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
SLIRP SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 41 3 3 0
SPX SPX Q9BT56 Spexin chr12 Not Cancer Driver No 1 hippie, biogrid 22 40 8 8 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 6
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 21 111 2 2 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 25 110 15 15 1
TMEM184A TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 Not Cancer Driver No 2 hippie, biogrid 59 76 17 17 0
TMEM70 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 26 24 4 4 1
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 74 110 11 11 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 hippie 48 123 10 10 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 37 73 7 7 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 50 3 3 1