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HSPG2 ,HSPG2 ,P98160
  • Uniprot Accession= P98160
  • Ensembl Transcript= ENST00000374695.7
  • Uniprot Name= HSPG2
  • Name= Basement membrane-specific heparan sulfate proteoglycan core protein
  • Chromosome= chr1
  • Driver status= Compendium
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 89
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AC244197.3 IDS B3KWA1 Iduronate 2-sulfatase (Hunter syndrome), isoform CRA_e chrX Not Cancer Driver No 1 hippie, biogrid 57 21 3 3 0
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 Not Cancer Driver No 1 hippie 106 439 64 64 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 Compendium Yes 1 hippie 160 1136 139 139 0
ATN1_ENST00000396684 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 hippie 141 1176 139 139 6
B4GALT4 B4GALT4 O60513 Beta-1,4-galactosyltransferase 4 chr3 Not Cancer Driver No 1 hippie, biogrid 49 14 4 4 0
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 Not Cancer Driver No 1 hippie 119 154 25 25 3
BRICD5_ENST00000562360 BRICD5 Q6PL45 BRICHOS domain-containing protein 5 chr16 Not Cancer Driver No 1 hippie, biogrid 43 82 11 11 0
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 Not Cancer Driver No 1 hippie 436 1144 132 132 46
CAMKV CAMKV Q8NCB2 CaM kinase-like vesicle-associated protein chr3 Not Cancer Driver No 1 hippie, biogrid 87 226 30 30 0
CCDC22 CCDC22 O60826 Coiled-coil domain-containing protein 22 chrX Not Cancer Driver No 1 hippie 62 243 18 18 2
CCN2 CCN2 P29279 CCN family member 2 chr6 Not Cancer Driver No 1 hippie 58 0 0 0 0
CLEC14A CLEC14A Q86T13 C-type lectin domain family 14 member A chr14 Not Cancer Driver No 1 hippie 147 182 60 60 0
CNN1 CNN1 P51911 Calponin-1 chr19 Not Cancer Driver No 1 hippie 56 200 39 39 0
COL13A1 COL13A1 Q5TAT6 Collagen alpha-1(XIII) chain chr10 Not Cancer Driver No 1 hippie 126 690 126 126 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 Not Cancer Driver No 1 hippie 91 219 28 28 1
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 Not Cancer Driver No 1 hippie, biogrid 69 140 44 44 3
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FBLN1 FBLN1 P23142 Fibulin-1 chr22 Compendium Yes 1 hippie 122 22 3 3 0
FBLN2_ENST00000295760 FBLN2 P98095 Fibulin-2 chr3 Census Yes 1 hippie 151 340 44 44 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 Not Cancer Driver No 1 hippie 466 110 16 16 360
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 2 hippie, biogrid 31 27 3 3 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 Not Cancer Driver No 2 hippie, biogrid 30 29 2 2 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 Not Cancer Driver No 1 hippie 18 183 5 5 0
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 Not Cancer Driver No 1 hippie, biogrid 16 21 3 3 0
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 Not Cancer Driver No 1 hippie 38 22 4 4 0
FGFBP1 FGFBP1 Q14512 Fibroblast growth factor-binding protein 1 chr4 Not Cancer Driver No 1 hippie 28 81 8 8 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 152 230 43 43 74
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 hippie 173 241 26 26 37
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 Not Cancer Driver No 1 hippie, biogrid 22 154 17 17 0
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie 546 1442 288 288 7
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 Not Cancer Driver No 1 hippie 299 103 20 20 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FNDC5_ENST00000640867 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 17 74 8 8 0
GAA_ENST00000390015 GAA P10253 Lysosomal alpha-glucosidase chr17 Not Cancer Driver No 1 hippie, biogrid 101 147 18 18 131
GAR1 GAR1 Q9NY12 H/ACA ribonucleoprotein complex subunit 1 chr4 Not Cancer Driver No 1 hippie 23 141 14 14 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 Not Cancer Driver No 1 hippie, biogrid 72 53 15 15 0
GFI1B GFI1B Q5VTD9 Zinc finger protein Gfi-1b chr9 Not Cancer Driver No 1 hippie 50 142 23 23 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 Not Cancer Driver No 1 hippie 385 1352 327 327 7
GPC5 GPC5 P78333 Glypican-5 chr13 Census Yes 1 hippie, biogrid 239 117 56 56 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 Not Cancer Driver No 1 hippie 124 118 12 12 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
IDS IDS P22304 Iduronate 2-sulfatase chrX Not Cancer Driver No 1 hippie, biogrid 91 85 13 13 126
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 183 265 37 37 6
IL17F IL17F Q96PD4 Interleukin-17F chr6 Not Cancer Driver No 1 hippie, biogrid 42 34 11 11 1
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 Not Cancer Driver No 1 hippie, biogrid 92 23 5 5 0
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 Not Cancer Driver No 1 hippie 37 43 1 1 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 Not Cancer Driver No 1 hippie 166 26 0 0 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie 103 84 10 10 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 Census, Compendium Yes 1 hippie 357 275 55 55 2
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 Not Cancer Driver No 1 hippie 150 844 104 104 5
LAMA1 LAMA1 P25391 Laminin subunit alpha-1 chr18 Not Cancer Driver No 1 hippie 600 329 71 71 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 Not Cancer Driver No 1 hippie, biogrid 91 86 17 17 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MTDH MTDH Q86UE4 Protein LYRIC chr8 Not Cancer Driver No 1 hippie 83 516 81 81 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NID1 NID1 P14543 Nidogen-1 chr1 Not Cancer Driver No 1 hippie 246 340 72 72 0
NID2 NID2 Q14112 Nidogen-2 chr14 Not Cancer Driver No 1 hippie 270 415 96 96 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 Not Cancer Driver No 1 hippie 31 75 10 10 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 Census Yes 1 hippie 37 99 22 22 2
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 hippie 33 121 12 12 0
PI15 PI15 O43692 Peptidase inhibitor 15 chr8 Not Cancer Driver No 1 hippie, biogrid 87 4 1 1 0
PRELP PRELP P51888 Prolargin chr1 Not Cancer Driver No 1 hippie 63 55 13 13 0
PRG2 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie, biogrid 45 65 15 15 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSAT1 PSAT1 Q9Y617 Phosphoserine aminotransferase chr9 Not Cancer Driver No 1 hippie, biogrid 54 3 1 1 3
PTTG1_ENST00000520452 PTTG1 O95997 Securin chr5 Not Cancer Driver No 1 hippie 17 141 6 6 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 174 291 99 99 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SIRPD SIRPD Q9H106 Signal-regulatory protein delta chr20 Not Cancer Driver No 1 hippie, biogrid 58 66 17 17 0
SKI SKI P12755 Ski oncogene chr1 Census Yes 1 hippie 44 432 26 26 14
SPARC SPARC P09486 SPARC chr5 Not Cancer Driver No 1 hippie 60 69 5 5 2
TCAP TCAP O15273 Telethonin chr17 Not Cancer Driver No 1 hippie 16 94 10 10 3
TINAGL1 TINAGL1 Q9GZM7 Tubulointerstitial nephritis antigen-like chr1 Not Cancer Driver No 3 hippie, biogrid 62 89 15 15 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TTR TTR P02766 Transthyretin chr18 Not Cancer Driver No 1 hippie 28 25 8 8 75
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 66 218 29 29 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VWA1 VWA1 Q6PCB0 von Willebrand factor A domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 18 221 10 10 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
ZNF408 ZNF408 Q9H9D4 Zinc finger protein 408 chr11 Not Cancer Driver No 2 hippie, biogrid 79 432 40 40 2
ZNF444 ZNF444 Q8N0Y2 Zinc finger protein 444 chr19 Not Cancer Driver No 1 hippie, biogrid 17 221 13 13 0