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HSPA6 ,HSPA6 ,P17066
  • Uniprot Accession= P17066
  • Ensembl Transcript= ENST00000309758.5
  • Uniprot Name= HSPA6
  • Name= Heat shock 70 kDa protein 6
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 70
  • Number of Interaction partner in biogrid: 58
  • Number of Interaction partner in hippie: 235
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABHD15 ABHD15 Q6UXT9 Protein ABHD15 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 50 41 3 3 0
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 1 intact, hippie 55 360 39 39 0
ADCK5 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 intact, hippie 51 5 2 2 0
AGBL4 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 65 72 2 2 0
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 intact, hippie 58 108 10 10 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 intact, hippie 108 158 24 24 4
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 hippie, biogrid 47 5 2 2 26
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 1 hippie 55 41 9 9 1
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie 168 341 64 64 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 1 hippie 14 163 14 14 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 2 hippie, biogrid 29 195 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie, biogrid 57 571 57 57 7
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 55 402 49 49 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie, biogrid 37 63 7 7 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 Census Yes 1 intact, hippie 44 259 23 23 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 intact, hippie 791 310 43 43 39
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
C22orf15_ENST00000402217 C22orf15 Q8WYQ4 Uncharacterized protein C22orf15 chr22 Not Cancer Driver No 1 intact, hippie 14 60 6 6 0
C3orf38 C3orf38 Q5JPI3 Uncharacterized protein C3orf38 chr3 Not Cancer Driver No 1 hippie, biogrid 40 50 6 6 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CCDC117 CCDC117 Q8IWD4 Coiled-coil domain-containing protein 117 chr22 Not Cancer Driver No 1 hippie, biogrid 27 255 22 22 0
CCNI2_ENST00000378731 CCNI2 Q6ZMN8 Cyclin-I2 chr5 Not Cancer Driver No 1 hippie, biogrid 15 126 0 0 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDK20 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 Not Cancer Driver No 1 hippie, biogrid 36 32 1 1 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie, biogrid 50 34 2 2 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CISH_ENST00000348721 CISH Q9NSE2 Cytokine-inducible SH2-containing protein chr3 Not Cancer Driver No 1 hippie 33 97 8 8 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLTA CLTA P09496 Clathrin light chain A chr9 Not Cancer Driver No 1 hippie, biogrid 20 192 12 12 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 190 71 6 6 1
CLUAP1_ENST00000576634 CLUAP1 Q96AJ1 Clusterin-associated protein 1 chr16 Not Cancer Driver No 1 hippie 48 203 22 22 0
COMMD6_ENST00000377615 COMMD6 Q7Z4G1 COMM domain-containing protein 6 chr13 Not Cancer Driver No 1 intact, hippie 11 12 2 2 0
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 1 hippie 106 147 11 11 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CPLANE2 CPLANE2 Q9BU20 Ciliogenesis and planar polarity effector 2 chr1 Not Cancer Driver No 1 hippie 37 21 3 3 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 intact, hippie 41 18 1 1 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 151 65 9 9 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
CYP4F12_ENST00000324632 CYP4F12 Q9HCS2 Cytochrome P450 4F12 chr19 Not Cancer Driver No 1 intact, hippie 138 18 4 4 0
DHRS13 DHRS13 Q6UX07 Dehydrogenase/reductase SDR family member 13 chr17 Not Cancer Driver No 1 hippie, biogrid 26 101 8 8 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie 37 153 16 16 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie 50 174 27 27 0
DNAJA4_ENST00000394852 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 Not Cancer Driver No 1 hippie 43 110 6 6 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 2 hippie, biogrid 35 196 26 26 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 52 141 21 21 2
DNAJB2 DNAJB2 P25686 DnaJ homolog subfamily B member 2 chr2 Not Cancer Driver No 2 hippie, biogrid 51 239 40 40 1
DNAJB4 DNAJB4 Q9UDY4 DnaJ homolog subfamily B member 4 chr1 Not Cancer Driver No 1 intact, hippie 41 160 20 20 0
DNAJB5_ENST00000312316 DNAJB5 O75953 DnaJ homolog subfamily B member 5 chr9 Not Cancer Driver No 1 hippie 49 147 18 18 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie 33 198 17 17 3
DNAJB7 DNAJB7 Q7Z6W7 DnaJ homolog subfamily B member 7 chr22 Not Cancer Driver No 1 hippie 43 138 21 21 0
DNAJB8_ENST00000319153 DNAJB8 Q8NHS0 DnaJ homolog subfamily B member 8 chr3 Not Cancer Driver No 1 hippie 64 92 30 30 0
DNAJC13 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 1 hippie, biogrid 276 141 17 17 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie, biogrid 41 102 9 9 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 Not Cancer Driver No 1 hippie 43 39 3 3 4
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 hippie 77 294 39 39 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 Not Cancer Driver No 1 intact, hippie 46 253 20 20 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF4B_ENST00000262056 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 hippie 94 589 90 90 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX Not Cancer Driver No 1 intact, hippie 51 327 34 34 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 90 92 11 11 1
F12 F12 P00748 Coagulation factor XII chr5 Not Cancer Driver No 1 hippie, biogrid 53 104 9 9 13
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FAM83F FAM83F Q8NEG4 Protein FAM83F chr22 Not Cancer Driver No 1 hippie, biogrid 65 255 27 27 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 Not Cancer Driver No 1 hippie 133 440 48 48 1
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 152 230 43 43 74
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FUNDC1 FUNDC1 Q8IVP5 FUN14 domain-containing protein 1 chrX Not Cancer Driver No 1 hippie 16 24 2 2 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GAL GAL P22466 Galanin peptides chr11 Not Cancer Driver No 1 hippie, biogrid 17 36 2 2 1
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 74 33 6 6 19
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 hippie, biogrid 50 21 0 0 7
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 Not Cancer Driver No 1 intact, hippie 94 220 38 38 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 intact, hippie 112 124 25 25 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 intact, hippie 47 135 10 10 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 intact, hippie 39 206 19 19 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 3 hippie, biogrid 24 200 13 13 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 119 141 28 28 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie, biogrid 80 351 24 24 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 73 282 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie 149 251 52 52 0
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 29 130 7 7 0
HTRA3 HTRA3 P83110 Serine protease HTRA3 chr4 Not Cancer Driver No 1 intact, hippie 64 57 11 11 0
IFT27 IFT27 Q9BW83 Intraflagellar transport protein 27 homolog chr22 Not Cancer Driver No 1 hippie 14 0 0 0 1
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 6 301 6 6 22
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie, biogrid 45 71 9 9 0
INPPL1 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 Not Cancer Driver No 1 hippie 174 566 76 76 4
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 Not Cancer Driver No 1 hippie 47 11 3 3 0
IQCB1 IQCB1 Q15051 IQ calmodulin-binding motif-containing protein 1 chr3 Not Cancer Driver No 1 hippie 72 88 8 8 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KIAA1191_ENST00000510164 KIAA1191 Q96A73 Putative monooxygenase p33MONOX chr5 Not Cancer Driver No 1 hippie, biogrid 25 288 22 22 0
KLHL34 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 intact, hippie, biogrid 103 77 12 12 0
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 Census Yes 1 hippie 75 246 67 67 0
KRT222 KRT222 Q8N1A0 Keratin-like protein KRT222 chr17 Not Cancer Driver No 1 intact, hippie 51 132 18 18 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LIME1 LIME1 Q9H400 Lck-interacting transmembrane adapter 1 chr20 Not Cancer Driver No 1 hippie, biogrid 22 193 17 17 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LRRC28 LRRC28 Q86X40 Leucine-rich repeat-containing protein 28 chr15 Not Cancer Driver No 1 hippie, biogrid 52 0 0 0 0
LRRC8E LRRC8E Q6NSJ5 Volume-regulated anion channel subunit LRRC8E chr19 Not Cancer Driver No 1 hippie, biogrid 77 35 0 0 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 10 17 1 1 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 104 75 27 27 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 Not Cancer Driver No 1 intact, hippie 40 85 10 10 0
MAP3K1 MAP3K1 Q13233 Mitogen-activated protein kinase kinase kinase 1 chr5 Census, Compendium Yes 1 hippie 184 820 62 62 3
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 2 intact, hippie 94 543 52 52 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 76 446 42 42 0
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie 37 187 32 32 0
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 hippie, biogrid 37 45 3 3 0
MOCS3 MOCS3 O95396 Adenylyltransferase and sulfurtransferase MOCS3 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 61 15 5 5 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 hippie, biogrid 126 61 6 6 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NDRG2 NDRG2 Q9UN36 Protein NDRG2 chr14 Not Cancer Driver No 1 hippie, biogrid 45 111 8 8 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 intact, hippie 102 167 40 40 3
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 2 intact, hippie 104 344 38 38 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact, hippie 86 510 46 46 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie 207 201 33 33 0
NPHP4 NPHP4 O75161 Nephrocystin-4 chr1 Not Cancer Driver No 1 intact, hippie 176 469 54 54 17
NR1I3_ENST00000367982 NR1I3 Q14994 Nuclear receptor subfamily 1 group I member 3 chr1 Not Cancer Driver No 1 hippie, biogrid 60 23 5 5 0
NTNG1_ENST00000370073 NTNG1 Q9Y2I2 Netrin-G1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 149 1 0 0 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF5_ENST00000537026 NXF5 Q9H1B4 Nuclear RNA export factor 5 chrX Not Cancer Driver No 1 hippie, biogrid 92 4 3 3 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 Not Cancer Driver No 1 intact, hippie 76 8 4 4 0
ODF3L1 ODF3L1 Q8IXM7 Outer dense fiber protein 3-like protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 32 122 18 18 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 intact, hippie 57 299 30 30 2
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie 200 1144 170 170 2
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 intact, hippie 33 121 12 12 0
PELI3 PELI3 Q8N2H9 E3 ubiquitin-protein ligase pellino homolog 3 chr11 Not Cancer Driver No 1 hippie, biogrid 48 216 25 25 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 1 hippie 96 418 47 47 3
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PNPLA5 PNPLA5 Q7Z6Z6 Patatin-like phospholipase domain-containing protein 5 chr22 Not Cancer Driver No 1 hippie, biogrid 78 33 8 8 0
POC1A POC1A Q8NBT0 POC1 centriolar protein homolog A chr3 Not Cancer Driver No 2 hippie, biogrid 51 88 8 8 1
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 1 intact, hippie 28 16 1 1 1
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 70 73 12 12 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 Not Cancer Driver No 1 intact, hippie 14 124 13 13 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 Not Cancer Driver No 1 intact, hippie 172 151 43 43 5
PRKCI PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie 110 120 16 16 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie 70 116 11 11 0
PRODH_ENST00000610940 PRODH O43272 Proline dehydrogenase 1, mitochondrial chr22 Not Cancer Driver No 1 intact, hippie, biogrid 62 67 8 8 16
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSMB2 PSMB2 P49721 Proteasome subunit beta type-2 chr1 Not Cancer Driver No 1 hippie 24 0 0 0 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 42 12 0 0 0
PTMA PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie 10 111 10 10 0
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 Not Cancer Driver No 1 intact, hippie 102 516 60 60 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 intact, hippie 62 341 24 24 0
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 intact, hippie 89 169 38 38 22
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 73 413 30 30 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 intact, hippie 68 363 43 43 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RELB RELB Q01201 Transcription factor RelB chr19 Not Cancer Driver No 1 intact, hippie 65 348 39 39 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 Not Cancer Driver No 1 hippie, biogrid 50 150 21 21 0
RFPL2 RFPL2 O75678 Ret finger protein-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 77 71 21 21 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 intact, hippie 63 143 20 20 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 Not Cancer Driver No 1 hippie 25 82 15 15 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPAP3 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 59 334 37 37 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 94 178 32 32 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX Compendium Yes 1 hippie 106 145 18 18 13
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 54 194 16 16 0
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 66 117 12 12 0
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SKI SKI P12755 Ski oncogene chr1 Census Yes 1 hippie 44 432 26 26 14
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SNIP1 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 intact, hippie 58 285 40 40 1
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 Census, Compendium Yes 1 intact, hippie 22 66 3 3 2
SPDL1 SPDL1 Q96EA4 Protein Spindly chr5 Not Cancer Driver No 1 hippie 75 342 43 43 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 intact, hippie 70 231 30 30 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 Not Cancer Driver No 1 intact 20 30 2 2 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 222 761 107 107 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 intact, hippie 81 232 34 34 0
TEDC1_ENST00000392523 TEDC1 Q86SX3 Tubulin epsilon and delta complex protein 1 chr14 Not Cancer Driver No 1 hippie 25 160 6 6 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 63 220 34 34 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 191 1663 176 176 1
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 Not Cancer Driver No 1 hippie 141 35 3 3 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact, hippie 58 111 15 15 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 intact, hippie 48 229 28 28 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 intact, hippie 17 43 6 6 0
TRABD_ENST00000395827 TRABD Q9H4I3 TraB domain-containing protein chr22 Not Cancer Driver No 1 hippie, biogrid 38 66 6 6 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 75 507 60 60 4
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 hippie 85 49 7 7 0
TSSK1B TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 Not Cancer Driver No 1 hippie, biogrid 104 114 36 36 0
TTC30B TTC30B Q8N4P2 Tetratricopeptide repeat protein 30B chr2 Not Cancer Driver No 1 intact, hippie, biogrid 80 74 13 13 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 59 52 11 11 8
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie 67 53 10 10 12
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 Not Cancer Driver No 1 hippie 101 27 8 8 0
UBL4A UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 1 hippie 22 16 5 5 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 Not Cancer Driver No 1 hippie, biogrid 39 215 18 18 0
VILL_ENST00000383759 VILL O15195 Villin-like protein chr3 Not Cancer Driver No 1 intact, hippie, biogrid 100 222 28 28 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 Not Cancer Driver No 1 hippie 65 180 18 18 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZFYVE21_ENST00000311141 ZFYVE21 Q9BQ24 Zinc finger FYVE domain-containing protein 21 chr14 Not Cancer Driver No 1 hippie 28 19 0 0 0