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HS2ST1 ,HS2ST1 ,Q7LGA3
  • Uniprot Accession= Q7LGA3
  • Ensembl Transcript= ENST00000370550.9
  • Uniprot Name= HS2ST1
  • Name= Heparan sulfate 2-O-sulfotransferase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 78
  • Number of Interaction partner in hippie: 93
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCB8 ABCB8 Q9NUT2 Mitochondrial potassium channel ATP-binding subunit chr7 Not Cancer Driver No 1 hippie, biogrid 117 55 5 5 0
ACAD10_ENST00000313698 ACAD10 Q6JQN1 Acyl-CoA dehydrogenase family member 10 chr12 Not Cancer Driver No 1 hippie, biogrid 143 91 19 19 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
AGPAT5 AGPAT5 Q9NUQ2 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon chr8 Not Cancer Driver No 1 hippie, biogrid 33 39 5 5 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 Not Cancer Driver No 1 hippie 73 229 30 30 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie, biogrid 128 418 71 71 17
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 Not Cancer Driver No 1 hippie, biogrid 101 49 1 1 0
ATP12A_ENST00000381946 ATP12A P54707 Potassium-transporting ATPase alpha chain 2 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 203 117 24 24 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 200 115 29 29 31
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 130 147 16 16 0
BRI3BP BRI3BP Q8WY22 BRI3-binding protein chr12 Not Cancer Driver No 1 hippie, biogrid 30 18 3 3 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 Not Cancer Driver No 1 hippie, biogrid 28 72 12 12 0
CDS2 CDS2 O95674 Phosphatidate cytidylyltransferase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 49 4 4 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 Not Cancer Driver No 1 hippie, biogrid 76 23 6 6 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 73 409 55 55 0
CSPG5 CSPG5 O95196 Chondroitin sulfate proteoglycan 5 chr3 Not Cancer Driver No 1 hippie, biogrid 75 397 46 46 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 211 86 11 11 3
DCAF6_ENST00000312263 DCAF6 Q58WW2 DDB1- and CUL4-associated factor 6 chr1 Not Cancer Driver No 1 hippie, biogrid 127 460 70 70 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DIAPH3 DIAPH3 Q9NSV4 Protein diaphanous homolog 3 chr13 Not Cancer Driver No 3 hippie, biogrid 189 492 78 78 0
DNAJC11 DNAJC11 Q9NVH1 DnaJ homolog subfamily C member 11 chr1 Not Cancer Driver No 1 hippie, biogrid 66 123 14 14 0
DPY19L1 DPY19L1 Q2PZI1 Probable C-mannosyltransferase DPY19L1 chr7 Not Cancer Driver No 1 hippie, biogrid 86 26 0 0 0
DYM DYM Q7RTS9 Dymeclin chr18 Not Cancer Driver No 3 intact, hippie, biogrid 78 21 0 0 3
EPHX4 EPHX4 Q8IUS5 Epoxide hydrolase 4 chr1 Not Cancer Driver No 1 hippie, biogrid 60 1 0 0 0
ERGIC1 ERGIC1 Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 38 26 2 2 0
ERGIC3_ENST00000348547 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 Not Cancer Driver No 1 hippie, biogrid 53 23 3 3 0
ERMP1 ERMP1 Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 chr9 Not Cancer Driver No 1 hippie, biogrid 80 93 4 4 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 96 26 5 5 0
FUT1_ENST00000645652 FUT1 P19526 Galactoside alpha-(1,2)-fucosyltransferase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 63 17 3 3 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 Not Cancer Driver No 1 hippie 47 138 17 17 0
GPAA1 GPAA1 O43292 Glycosylphosphatidylinositol anchor attachment 1 protein chr8 Not Cancer Driver No 1 hippie, biogrid 55 20 3 3 5
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 Not Cancer Driver No 1 hippie, biogrid 82 75 19 19 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 291 43 5 5 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 2 intact, hippie, biogrid 128 125 60 60 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 Not Cancer Driver No 1 hippie, biogrid 94 85 22 22 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HS2ST1 HS2ST1 Q7LGA3 Heparan sulfate 2-O-sulfotransferase 1 chr1 Not Cancer Driver No 1 intact 60 44 8 8 3
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
ITGA7_ENST00000555728 ITGA7 Q13683 Integrin alpha-7 chr12 Not Cancer Driver No 1 hippie, biogrid 205 283 48 48 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 Not Cancer Driver No 1 hippie 62 28 12 12 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LMF1 LMF1 Q96S06 Lipase maturation factor 1 chr16 Not Cancer Driver No 1 hippie, biogrid 57 44 5 5 0
LRBA LRBA P50851 Lipopolysaccharide-responsive and beige-like anchor protein chr4 Not Cancer Driver No 1 hippie, biogrid 350 709 82 82 1
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 91 300 19 19 0
NMNAT3 NMNAT3 Q96T66 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 32 53 6 6 0
NOMO1 NOMO1 Q15155 Nodal modulator 1 chr16 Not Cancer Driver No 1 hippie, biogrid 130 128 23 23 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 151 126 24 24 41
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 62 104 13 13 2
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 Not Cancer Driver No 1 hippie, biogrid 67 60 13 13 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 Not Cancer Driver No 1 hippie, biogrid 129 254 37 37 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 Not Cancer Driver No 1 hippie 137 99 7 7 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 33 121 12 12 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 41 266 38 38 0
PGRMC2_ENST00000296425 PGRMC2 O15173 Membrane-associated progesterone receptor component 2 chr4 Not Cancer Driver No 1 hippie, biogrid 16 83 4 4 0
PIGK PIGK Q92643 GPI-anchor transamidase chr1 Not Cancer Driver No 1 hippie, biogrid 54 37 9 9 5
PIGS PIGS Q96S52 GPI transamidase component PIG-S chr17 Not Cancer Driver No 1 hippie, biogrid 59 32 4 4 2
PIGT PIGT Q969N2 GPI transamidase component PIG-T chr20 Not Cancer Driver No 1 hippie, biogrid 51 36 6 6 1
PIGU PIGU Q9H490 Phosphatidylinositol glycan anchor biosynthesis class U protein chr20 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 2
PON2 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 46 13 3 3 0
PON3 PON3 Q15166 Serum paraoxonase/lactonase 3 chr7 Not Cancer Driver No 1 hippie, biogrid 69 32 6 6 0
PTDSS2 PTDSS2 Q9BVG9 Phosphatidylserine synthase 2 chr11 Not Cancer Driver No 1 hippie, biogrid 41 92 4 4 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 Census, Compendium Yes 1 hippie, biogrid 560 623 75 75 3
SAAL1 SAAL1 Q96ER3 Protein SAAL1 chr11 Not Cancer Driver No 1 hippie, biogrid 46 75 11 11 0
SCFD2 SCFD2 Q8WU76 Sec1 family domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 96 24 4 4 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SERINC2_ENST00000373709 SERINC2 Q96SA4 Serine incorporator 2 chr1 Not Cancer Driver No 1 hippie, biogrid 49 6 0 0 0
SLC5A3 SLC5A3 P53794 Sodium/myo-inositol cotransporter chr21 Not Cancer Driver No 1 hippie, biogrid 81 73 6 6 0
SLC7A1 SLC7A1 P30825 High affinity cationic amino acid transporter 1 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 89 17 3 3 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 Not Cancer Driver No 1 hippie, biogrid 70 15 2 2 0
SOGA3 SOGA3 Q5TF21 Protein SOGA3 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 180 792 137 137 0
SPG7 SPG7 Q9UQ90 Paraplegin chr16 Not Cancer Driver No 1 hippie, biogrid 97 181 29 29 4
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 68 99 17 17 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
TBC1D23 TBC1D23 Q9NUY8 TBC1 domain family member 23 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 75 147 19 19 0
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 399 46 46 0
TMEM184A TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 Not Cancer Driver No 1 hippie, biogrid 59 76 17 17 0
TMEM258 TMEM258 P61165 Transmembrane protein 258 chr11 Not Cancer Driver No 1 hippie 13 0 0 0 0
TMX3 TMX3 Q96JJ7 Protein disulfide-isomerase TMX3 chr18 Not Cancer Driver No 1 hippie, biogrid 50 49 9 9 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 Not Cancer Driver No 1 hippie, biogrid 58 18 1 1 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TSPAN17_ENST00000515708 TSPAN17 Q96FV3 Tetraspanin-17 chr5 Not Cancer Driver No 2 hippie, biogrid 23 0 0 0 0
USE1 USE1 Q9NZ43 Vesicle transport protein USE1 chr19 Not Cancer Driver No 1 hippie, biogrid 31 101 19 19 0
USP9Y USP9Y O00507 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y chrY Not Cancer Driver No 1 intact, hippie, biogrid 83 349 6 6 0
UXS1_ENST00000409501 UXS1 Q8NBZ7 UDP-glucuronic acid decarboxylase 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 70 69 9 9 0
VAC14 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 97 116 19 19 3