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HMGN2 ,HMGN2 ,P05204
  • Uniprot Accession= P05204
  • Ensembl Transcript= ENST00000361427.5
  • Uniprot Name= HMGN2
  • Name= Non-histone chromosomal protein HMG-17
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 78
  • Number of Interaction partner in biogrid: 16
  • Number of Interaction partner in hippie: 124
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCF1 ABCF1 Q8NE71 ATP-binding cassette sub-family F member 1 chr6 Not Cancer Driver No 1 hippie 106 445 64 64 0
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 Not Cancer Driver No 1 intact, hippie 36 87 9 9 0
ALPK3 ALPK3 Q96L96 Alpha-protein kinase 3 chr15 Not Cancer Driver No 1 intact, hippie 264 1436 176 176 0
ANKRD31 ANKRD31 Q8N7Z5 Ankyrin repeat domain-containing protein 31 chr5 Not Cancer Driver No 1 intact, hippie 62 1144 34 34 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARHGAP27 ARHGAP27 Q6ZUM4 Rho GTPase-activating protein 27 chr17 Not Cancer Driver No 1 intact, hippie 91 516 57 57 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX Not Cancer Driver No 1 hippie 125 464 76 76 0
ASF1A ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 1 hippie, biogrid 18 69 2 2 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 intact, hippie 205 1300 174 174 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATPAF2 ATPAF2 Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 chr17 Not Cancer Driver No 1 intact, hippie 25 66 4 4 1
ATRIP ATRIP Q8WXE1 ATR-interacting protein chr3 Not Cancer Driver No 1 hippie, biogrid 76 383 32 32 0
ATXN7L1 ATXN7L1 Q9ULK2 Ataxin-7-like protein 1 chr7 Not Cancer Driver No 1 intact, hippie 60 710 48 48 0
BAZ2B BAZ2B Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B chr2 Not Cancer Driver No 1 intact, hippie 293 1491 206 206 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 Not Cancer Driver No 1 intact, hippie 45 95 7 7 0
CAST_ENST00000395813 CAST P20810 Calpastatin chr5 Not Cancer Driver No 1 intact, hippie 73 708 73 73 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 1 intact, hippie 23 119 18 18 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 1 hippie, biogrid 15 50 4 4 0
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 Not Cancer Driver No 1 intact, hippie 393 1469 213 213 0
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 Not Cancer Driver No 2 intact, hippie, biogrid 18 110 6 6 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FLYWCH1 FLYWCH1 Q4VC44 FLYWCH-type zinc finger-containing protein 1 chr16 Not Cancer Driver No 1 hippie 66 432 38 38 0
GBE1 GBE1 Q04446 1,4-alpha-glucan-branching enzyme chr3 Not Cancer Driver No 2 hippie, biogrid 101 8 0 0 9
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 Not Cancer Driver No 1 intact, hippie 83 261 33 33 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 Not Cancer Driver No 1 hippie 77 87 8 8 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 Not Cancer Driver No 1 intact 46 125 19 19 0
H2BFS H2BC12L P57053 Histone H2B type F-S chr21 Not Cancer Driver No 1 intact 1 86 1 1 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 Not Cancer Driver No 1 hippie 487 1344 129 129 1
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 Not Cancer Driver No 1 intact 37 210 35 35 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 66 224 66 66 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 Not Cancer Driver No 1 intact 66 213 63 63 0
HIST1H2AH H2AC12 Q96KK5 Histone H2A type 1-H chr6 Not Cancer Driver No 1 intact 31 55 12 12 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 31 14 14 0
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 Not Cancer Driver No 1 intact 47 77 30 30 0
HIST2H3C H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 1 51 0 0 0
HIST2H3D H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 29 51 11 11 0
HIST3H3 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 37 51 10 10 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 21 31 7 7 0
HMGN1 HMGN1 P05114 Non-histone chromosomal protein HMG-14 chr21 Not Cancer Driver No 2 hippie, biogrid 12 100 12 12 0
HMGN2 HMGN2 P05204 Non-histone chromosomal protein HMG-17 chr1 Not Cancer Driver No 1 hippie 10 90 10 10 0
HMGN4 HMGN4 O00479 High mobility group nucleosome-binding domain-containing protein 4 chr6 Not Cancer Driver No 1 hippie, biogrid 9 90 9 9 0
HNF4G_ENST00000354370 HNF4G Q14541 Hepatocyte nuclear factor 4-gamma chr8 Not Cancer Driver No 1 intact, hippie 122 96 29 29 0
HPF1 HPF1 Q9NWY4 Histone PARylation factor 1 chr4 Not Cancer Driver No 1 hippie 32 23 0 0 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 Not Cancer Driver No 1 hippie 41 103 25 25 0
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 Not Cancer Driver No 1 intact, hippie 120 26 4 4 3
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 1 hippie 107 266 27 27 0
KCNK16_ENST00000373229 KCNK16 Q96T55 Potassium channel subfamily K member 16 chr6 Not Cancer Driver No 1 intact, hippie 63 14 1 1 0
KDM8_ENST00000286096 KDM8 Q8N371 Bifunctional peptidase and arginyl-hydroxylase JMJD5 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 52 29 6 6 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KLHL36 KLHL36 Q8N4N3 Kelch-like protein 36 chr16 Compendium Yes 2 intact, hippie, biogrid 67 48 3 3 0
KMT5A KMT5A Q9NQR1-2 Isoform 2 of N-lysine methyltransferase KMT5A chr12 Not Cancer Driver No 1 intact, hippie 41 225 22 22 0
LRRIQ4 LRRIQ4 A6NIV6 Leucine-rich repeat and IQ domain-containing protein 4 chr3 Not Cancer Driver No 1 intact, hippie 101 75 12 12 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MEGF10_ENST00000503335 MEGF10 Q96KG7 Multiple epidermal growth factor-like domains protein 10 chr5 Not Cancer Driver No 1 intact, hippie 216 204 42 42 2
MON2 MON2 Q7Z3U7 Protein MON2 homolog chr12 Not Cancer Driver No 1 intact, hippie 201 151 16 16 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 Not Cancer Driver No 1 intact, hippie 72 0 0 0 0
MXRA5 MXRA5 Q9NR99 Matrix-remodeling-associated protein 5 chrX Not Cancer Driver No 1 hippie 753 1392 397 397 1
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYL2 MYL2 P10916 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform chr12 Not Cancer Driver No 1 intact, hippie 44 34 8 8 6
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NEK11 NEK11 Q8NG66 Serine/threonine-protein kinase Nek11 chr3 Not Cancer Driver No 1 hippie 91 264 45 45 0
NIFK NIFK Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein chr2 Not Cancer Driver No 1 hippie, biogrid 32 148 15 15 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 Not Cancer Driver No 1 hippie 300 71 20 20 9
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OSER1 OSER1 Q9NX31 Oxidative stress-responsive serine-rich protein 1 chr20 Not Cancer Driver No 1 intact, hippie 32 221 28 28 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie 119 320 34 34 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 74 172 23 23 0
PCF11 PCF11 O94913 Pre-mRNA cleavage complex 2 protein Pcf11 chr11 Not Cancer Driver No 1 intact, hippie 211 1250 189 189 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PCLO PCLO Q9Y6V0 Protein piccolo chr7 Not Cancer Driver No 1 intact, hippie 1611 4237 1301 1301 0
PDCD11 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 1 intact, hippie 212 487 64 64 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 Not Cancer Driver No 1 intact, hippie 57 187 32 32 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX Not Cancer Driver No 1 intact, hippie 154 603 93 93 1
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PYGB PYGB P11216 Glycogen phosphorylase, brain form chr20 Not Cancer Driver No 1 intact, hippie, biogrid 118 29 5 5 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 32 65 15 15 0
RABEP1 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 Census, Compendium Yes 1 hippie 81 520 57 57 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 intact, hippie 41 12 3 3 0
RHOXF2 RHOXF2 Q9BQY4 Rhox homeobox family member 2 chrX Not Cancer Driver No 1 intact, hippie 32 156 23 23 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 hippie 68 253 33 33 0
RND1 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 Not Cancer Driver No 1 hippie 45 9 1 1 0
RPF2 RPF2 Q9H7B2 Ribosome production factor 2 homolog chr6 Not Cancer Driver No 1 intact, hippie 37 92 9 9 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 intact, hippie 21 70 13 13 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 hippie, biogrid 21 107 11 11 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie, biogrid 19 69 14 14 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX Compendium Yes 1 hippie 106 145 18 18 13
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 1 intact, hippie 23 81 7 7 0
SHOC2 SHOC2 Q9UQ13 Leucine-rich repeat protein SHOC-2 chr10 Not Cancer Driver No 1 hippie 55 110 12 12 2
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 intact, hippie 75 436 63 63 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 intact, hippie 64 141 35 35 3
SPATS1 SPATS1 Q496A3 Spermatogenesis-associated serine-rich protein 1 chr6 Not Cancer Driver No 1 intact, hippie 39 154 18 18 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie 78 343 46 46 0
STAC3 STAC3 Q96MF2 SH3 and cysteine-rich domain-containing protein 3 chr12 Not Cancer Driver No 1 intact, hippie 50 192 30 30 1
SUN2_ENST00000405510 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 Not Cancer Driver No 1 hippie 74 214 18 18 0
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie 308 1423 192 192 0
SYNE1 SYNE1 Q8NF91 Nesprin-1 chr6 Not Cancer Driver No 1 intact, hippie 1694 2530 530 530 2
TBC1D4 TBC1D4 O60343 TBC1 domain family member 4 chr13 Not Cancer Driver No 1 hippie 173 590 90 90 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 Not Cancer Driver No 1 intact, hippie 87 331 39 39 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 Census Yes 1 intact, hippie 40 179 24 24 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 Not Cancer Driver No 1 hippie 38 81 12 12 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 102 151 17 17 0
TPPP TPPP O94811 Tubulin polymerization-promoting protein chr5 Not Cancer Driver No 1 intact, hippie 33 149 21 21 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 Not Cancer Driver No 1 hippie 34 59 8 8 0
UBAC1 UBAC1 Q9BSL1 Ubiquitin-associated domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 38 241 23 23 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
USF3 USF3 Q68DE3 Basic helix-loop-helix domain-containing protein USF3 chr3 Not Cancer Driver No 1 hippie 286 2015 259 259 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
UTRN UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 intact, hippie 476 1283 183 183 0
WDR49 WDR49 Q8IV35 WD repeat-containing protein 49 chr3 Not Cancer Driver No 1 intact, hippie 232 73 31 31 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 Not Cancer Driver No 1 intact, hippie 278 1959 223 223 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact, hippie 26 77 9 9 2
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0