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HIST3H3 ,H3-4 ,Q16695
  • Uniprot Accession= Q16695
  • Ensembl Transcript= ENST00000366696.1
  • Uniprot Name= H3-4
  • Name= Histone H3.1t
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 120
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 0
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AMPD3_ENST00000529507 AMPD3 Q01432 AMP deaminase 3 chr11 Not Cancer Driver No 1 intact 132 207 38 38 10
ANKRD18A ANKRD18A Q8IVF6 Ankyrin repeat domain-containing protein 18A chr9 Not Cancer Driver No 1 intact 69 336 18 18 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 Not Cancer Driver No 1 intact 127 17 1 1 0
ARHGEF1_ENST00000354532 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 Not Cancer Driver No 1 intact 127 457 67 67 0
ARID3B ARID3B Q8IVW6 AT-rich interactive domain-containing protein 3B chr15 Not Cancer Driver No 1 intact 72 394 57 57 0
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 Not Cancer Driver No 1 intact 105 328 39 39 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 intact 115 546 73 73 10
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact 50 150 30 30 0
BRPF3 BRPF3 Q9ULD4 Bromodomain and PHD finger-containing protein 3 chr6 Not Cancer Driver No 1 intact 143 633 74 74 0
BSND BSND Q8WZ55 Barttin chr1 Not Cancer Driver No 1 intact 57 209 36 36 4
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 1 intact 83 62 10 10 7
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 Not Cancer Driver No 1 intact 74 75 16 16 4
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 Not Cancer Driver No 1 intact 31 154 25 25 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 1 intact 23 119 18 18 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 2 intact 21 116 12 12 0
CBX6 CBX6 O95503 Chromobox protein homolog 6 chr22 Not Cancer Driver No 1 intact 57 335 54 54 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 Not Cancer Driver No 1 intact 155 1138 99 99 6
CEP290 CEP290 O15078 Centrosomal protein of 290 kDa chr12 Not Cancer Driver No 1 intact 255 1421 152 152 3
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 intact 25 277 23 23 0
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 Not Cancer Driver No 1 intact 36 118 9 9 0
DDX10 DDX10 Q13206 Probable ATP-dependent RNA helicase DDX10 chr11 Census Yes 1 intact 93 400 46 46 0
DENND3 DENND3 A2RUS2 DENN domain-containing protein 3 chr8 Not Cancer Driver No 1 intact 192 118 22 22 0
DMD DMD P11532 Dystrophin chrX Not Cancer Driver No 1 intact 895 1399 329 329 14
DNAH10 DNAH10 Q8IVF4 Dynein axonemal heavy chain 10 chr12 Not Cancer Driver No 1 intact 802 220 31 31 0
DNAH5 DNAH5 Q8TE73 Dynein axonemal heavy chain 5 chr5 Not Cancer Driver No 1 intact 1431 296 111 111 12
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 Not Cancer Driver No 1 intact 365 458 69 69 0
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 intact 146 255 60 60 0
ELK4 ELK4 P28324 ETS domain-containing protein Elk-4 chr1 Census Yes 1 intact 46 239 26 26 0
ELMO3 ELMO3 Q96BJ8-3 Isoform 3 of Engulfment and cell motility protein 3 chr16 Not Cancer Driver No 1 intact 77 175 20 20 0
EML5_ENST00000380664 EML5 Q05BV3 Echinoderm microtubule-associated protein-like 5 chr14 Not Cancer Driver No 1 intact 255 140 11 11 0
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 Not Cancer Driver No 1 intact 204 372 62 62 1
FDXACB1 FDXACB1 Q9BRP7 Ferredoxin-fold anticodon-binding domain-containing protein 1 chr11 Not Cancer Driver No 1 intact 60 26 2 2 0
GATAD1 GATAD1 Q8WUU5 GATA zinc finger domain-containing protein 1 chr7 Not Cancer Driver No 1 intact 14 131 4 4 1
H1F0 H1-0 P07305 Histone H1.0 chr22 Not Cancer Driver No 1 intact 16 194 16 16 0
H1FX H1-10 Q92522 Histone H1.10 chr3 Not Cancer Driver No 1 intact 12 198 12 12 0
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 2 intact 20 68 10 10 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 Not Cancer Driver No 1 intact 23 71 16 16 0
H2BFS H2BC12L P57053 Histone H2B type F-S chr21 Not Cancer Driver No 1 intact 1 86 1 1 0
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 Not Cancer Driver No 1 intact 37 210 35 35 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 66 224 66 66 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 Not Cancer Driver No 1 intact 66 213 63 63 0
HIST1H2AH H2AC12 Q96KK5 Histone H2A type 1-H chr6 Not Cancer Driver No 1 intact 31 55 12 12 0
HIST1H2AJ H2AC14 Q99878 Histone H2A type 1-J chr6 Not Cancer Driver No 1 intact 28 56 11 11 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HIST1H2BL H2BC13 Q99880 Histone H2B type 1-L chr6 Not Cancer Driver No 1 intact 34 74 20 20 0
HIST1H2BM H2BC14 Q99879 Histone H2B type 1-M chr6 Not Cancer Driver No 1 intact 37 75 23 23 0
HIST1H2BN H2BC15 Q99877 Histone H2B type 1-N chr6 Not Cancer Driver No 1 intact 21 82 11 11 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 25 31 14 14 0
HIST2H2AB H2AC21 Q8IUE6 Histone H2A type 2-B chr1 Not Cancer Driver No 1 intact 33 61 17 17 0
HIST2H2AC H2AC20 Q16777 Histone H2A type 2-C chr1 Not Cancer Driver No 1 intact 39 56 18 18 0
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 Not Cancer Driver No 1 intact 47 77 30 30 0
HIST2H3C H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 1 51 0 0 0
HIST2H3D H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 29 51 11 11 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 2 intact 21 31 7 7 0
HLA-DOA HLA-DOA P06340 HLA class II histocompatibility antigen, DO alpha chain chr6 Not Cancer Driver No 1 intact 39 7 1 1 0
HMGN2 HMGN2 P05204 Non-histone chromosomal protein HMG-17 chr1 Not Cancer Driver No 1 intact 10 90 10 10 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 intact 77 504 45 45 0
HOOK1 HOOK1 Q9UJC3 Protein Hook homolog 1 chr1 Not Cancer Driver No 1 intact 97 427 59 59 0
HTR7 HTR7 P34969 5-hydroxytryptamine receptor 7 chr10 Not Cancer Driver No 1 intact 102 24 1 1 0
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 Not Cancer Driver No 1 intact 122 337 44 44 0
MAGOH MAGOH P61326 Protein mago nashi homolog chr1 Not Cancer Driver No 1 intact 15 6 0 0 0
MALSU1 MALSU1 Q96EH3 Mitochondrial assembly of ribosomal large subunit protein 1 chr7 Not Cancer Driver No 1 intact 17 34 0 0 0
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 Not Cancer Driver No 1 intact 62 454 56 56 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 intact 84 292 35 35 1
MYLK2 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 Not Cancer Driver No 1 intact 118 277 64 64 2
NASP NASP P49321 Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 1 intact 95 615 81 81 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 Not Cancer Driver No 1 intact 247 51 10 10 4
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 intact 85 569 68 68 0
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 Not Cancer Driver No 1 intact 173 713 130 130 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 intact 116 510 72 72 0
NUP50 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 intact 58 333 40 40 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 intact 227 1008 107 107 0
OTUD6B_ENST00000404789 OTUD6B Q8N6M0 Deubiquitinase OTUD6B chr8 Not Cancer Driver No 1 intact 35 152 18 18 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 Not Cancer Driver No 1 intact 93 137 14 14 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 intact 30 157 13 13 0
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 Not Cancer Driver No 1 intact 121 106 6 6 0
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 intact 677 2130 272 272 2
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 intact 144 869 114 114 0
POLK POLK Q9UBT6 DNA polymerase kappa chr5 Not Cancer Driver No 1 intact 97 293 36 36 0
PPP4R3A_ENST00000554943 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 Not Cancer Driver No 1 intact 89 255 29 29 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 intact 254 830 152 152 1
PRKCH PRKCH P24723 Protein kinase C eta type chr14 Not Cancer Driver No 1 intact 89 92 13 13 0
PSMB10 PSMB10 P40306 Proteasome subunit beta type-10 chr16 Not Cancer Driver No 1 intact 22 36 5 5 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 Not Cancer Driver No 1 intact 216 803 116 116 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 Not Cancer Driver No 1 intact 47 324 28 28 0
REPS2 REPS2 Q8NFH8 RalBP1-associated Eps domain-containing protein 2 chrX Not Cancer Driver No 1 intact 94 464 68 68 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 intact 41 12 3 3 0
RIPPLY1 RIPPLY1 Q0D2K3 Protein ripply1 chrX Not Cancer Driver No 1 intact 19 56 8 8 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 intact 14 29 4 4 0
SEC11A_ENST00000268220 SEC11A P67812 Signal peptidase complex catalytic subunit SEC11A chr15 Not Cancer Driver No 1 intact 20 0 0 0 0
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 Census, Compendium Yes 1 intact 349 1072 195 195 5
SMYD4 SMYD4 Q8IYR2 SET and MYND domain-containing protein 4 chr17 Not Cancer Driver No 1 intact 72 101 6 6 0
SPACA9 SPACA9 Q96E40 Sperm acrosome-associated protein 9 chr9 Not Cancer Driver No 1 intact 29 70 6 6 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 1 intact 1046 707 294 294 21
TAZ_ENST00000612460 TAFAZZIN Q16635 Tafazzin chrX Not Cancer Driver No 1 intact 33 12 0 0 10
TBC1D28 TBC1D28 Q2M2D7 TBC1 domain family member 28 chr17 Not Cancer Driver No 1 intact 36 61 12 12 0
THSD7B THSD7B Q9C0I4 Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1 intact 652 94 19 19 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact 58 111 15 15 12
TSPYL4 TSPYL4 Q9UJ04 Testis-specific Y-encoded-like protein 4 chr6 Not Cancer Driver No 1 intact 32 268 17 17 0
TTC17 TTC17 Q96AE7 Tetratricopeptide repeat protein 17 chr11 Not Cancer Driver No 1 intact 161 276 46 46 0
UBA52_ENST00000595683 UBA52 P62987 Ubiquitin-60S ribosomal protein L40 chr19 Not Cancer Driver No 1 intact 19 45 8 8 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 Not Cancer Driver No 1 intact 161 539 68 68 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact 188 110 28 28 0
VPS13B VPS13B Q7Z7G8 Intermembrane lipid transfer protein VPS13B chr8 Not Cancer Driver No 1 intact 660 635 106 106 5
VWF VWF P04275 von Willebrand factor chr12 Not Cancer Driver No 1 intact 456 91 16 16 43
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 Not Cancer Driver No 1 intact 22 187 17 17 0
ZNF395 ZNF395 Q9H8N7 Zinc finger protein 395 chr8 Not Cancer Driver No 1 intact 70 342 46 46 0
ZNF674 ZNF674 Q2M3X9 Zinc finger protein 674 chrX Not Cancer Driver No 1 intact 80 139 27 27 0
ZNF800_ENST00000393312 ZNF800 Q2TB10 Zinc finger protein 800 chr7 Not Cancer Driver No 1 intact 108 397 72 72 0