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HAX1 ,HAX1 ,O00165
  • Uniprot Accession= O00165
  • Ensembl Transcript= ENST00000328703.11
  • Uniprot Name= HAX1
  • Name= HCLS1-associated protein X-1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 121
  • Number of Interaction partner in biogrid: 242
  • Number of Interaction partner in hippie: 397
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABCB11 ABCB11 O95342 Bile salt export pump chr2 Not Cancer Driver No 1 hippie 233 124 24 24 21
ABCB1_ENST00000265724 ABCB1 P08183 ATP-dependent translocase ABCB1 chr7 Compendium Yes 1 hippie 367 103 31 31 0
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 Not Cancer Driver No 1 hippie 243 74 14 14 72
ABCB6 ABCB6 Q9NP58 ATP-binding cassette sub-family B member 6 chr2 Not Cancer Driver No 1 hippie, biogrid 87 27 1 1 11
ABCC4_ENST00000376887 ABCC4 O15439 ATP-binding cassette sub-family C member 4 chr13 Not Cancer Driver No 1 hippie 174 97 6 6 0
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 Not Cancer Driver No 1 hippie, biogrid 75 21 2 2 0
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 2 hippie, biogrid 74 36 6 6 0
ACBD5_ENST00000375888 ACBD5 Q5T8D3 Acyl-CoA-binding domain-containing protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 65 330 45 45 0
ADCK2 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 62 9 1 1 0
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 Not Cancer Driver No 1 hippie, biogrid 195 271 42 42 0
ADGRL1 ADGRL1 O94910 Adhesion G protein-coupled receptor L1 chr19 Not Cancer Driver No 1 hippie 163 562 57 57 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 72 162 10 10 22
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 2 intact, hippie, biogrid 88 166 22 22 11
AKAP10 AKAP10 O43572 A-kinase anchor protein 10, mitochondrial chr17 Not Cancer Driver No 1 hippie 51 304 16 16 0
AKAP11 AKAP11 Q9UKA4 A-kinase anchor protein 11 chr13 Not Cancer Driver No 1 hippie, biogrid 196 922 91 91 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 hippie, biogrid 47 5 2 2 26
ALMS1 ALMS1 Q8TCU4 Alstrom syndrome protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 537 3518 441 441 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 hippie 173 788 103 103 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 Not Cancer Driver No 1 hippie 73 229 30 30 0
AMPH AMPH P49418 Amphiphysin chr7 Not Cancer Driver No 2 hippie, biogrid 202 473 131 131 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 770 2844 566 566 4
APOD APOD P05090 Apolipoprotein D chr3 Not Cancer Driver No 3 intact, hippie, biogrid 34 13 2 2 0
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 2 hippie, biogrid 84 181 32 32 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 Not Cancer Driver No 1 hippie, biogrid 254 358 63 63 0
ARGLU1 ARGLU1 Q9NWB6 Arginine and glutamate-rich protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 37 246 33 33 0
ARHGAP19 ARHGAP19 Q14CB8 Rho GTPase-activating protein 19 chr10 Not Cancer Driver No 1 hippie, biogrid 70 179 21 21 0
ARHGAP36 ARHGAP36 Q6ZRI8 Rho GTPase-activating protein 36 chrX Not Cancer Driver No 1 intact, hippie, biogrid 194 132 61 61 0
ATG2B ATG2B Q96BY7 Autophagy-related protein 2 homolog B chr14 Not Cancer Driver No 1 hippie, biogrid 264 679 111 111 0
ATP4A ATP4A P20648 Potassium-transporting ATPase alpha chain 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 201 121 30 30 0
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP6V0A1_ENST00000343619 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 Not Cancer Driver No 1 hippie 98 85 14 14 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie, biogrid 37 63 7 7 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 Not Cancer Driver No 1 intact, hippie 81 0 0 0 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 45 190 19 19 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 Not Cancer Driver No 1 hippie 189 934 147 147 0
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 Not Cancer Driver No 1 hippie, biogrid 139 466 64 64 0
C12orf74_ENST00000544406 C12orf74 Q6ZR37-3 Isoform 3 of Pleckstrin homology domain-containing family G member 7 chr12 Not Cancer Driver No 1 hippie, biogrid 29 159 26 26 0
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 hippie, biogrid 287 368 52 52 1
CALB2 CALB2 P22676 Calretinin chr16 Not Cancer Driver No 2 intact, hippie, biogrid 54 39 8 8 0
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 3 intact, hippie, biogrid 83 62 10 10 7
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 Not Cancer Driver No 3 intact, hippie, biogrid 86 273 28 28 6
CAMKV CAMKV Q8NCB2 CaM kinase-like vesicle-associated protein chr3 Not Cancer Driver No 3 intact, hippie, biogrid 87 226 30 30 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 Census, Compendium Yes 1 hippie 39 94 17 17 0
CCDC138 CCDC138 Q96M89 Coiled-coil domain-containing protein 138 chr2 Not Cancer Driver No 1 hippie, biogrid 76 202 25 25 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 44 198 15 15 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 Not Cancer Driver No 1 hippie, biogrid 168 235 59 59 0
CDK20 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 36 32 1 1 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 Not Cancer Driver No 1 hippie, biogrid 217 1136 128 128 0
CDKAL1 CDKAL1 Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase chr6 Not Cancer Driver No 1 hippie, biogrid 80 120 14 14 0
CDKN3 CDKN3 Q16667 Cyclin-dependent kinase inhibitor 3 chr14 Not Cancer Driver No 1 hippie 13 33 1 1 9
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHCHD4_ENST00000396914 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 Not Cancer Driver No 1 hippie 18 82 8 8 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 58 86 16 16 0
CKB CKB P12277 Creatine kinase B-type chr14 Not Cancer Driver No 1 hippie, biogrid 31 102 4 4 0
CLCC1 CLCC1 Q96S66 Chloride channel CLIC-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 37 196 19 19 1
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 Not Cancer Driver No 2 hippie, biogrid 69 224 25 25 11
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 190 71 6 6 1
CLUAP1_ENST00000576634 CLUAP1 Q96AJ1 Clusterin-associated protein 1 chr16 Not Cancer Driver No 1 hippie 48 203 22 22 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 Not Cancer Driver No 2 hippie, biogrid 69 156 27 27 0
CNTN1 CNTN1 Q12860 Contactin-1 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 265 220 50 50 0
COX14_ENST00000550654 COX14 Q96I36 Cytochrome c oxidase assembly protein COX14 chr12 Not Cancer Driver No 1 intact, hippie 4 7 0 0 1
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 17 5 1 1 1
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 122 96 15 15 0
CRYBG3 CRYBG3 Q68DQ2 Very large A-kinase anchor protein chr3 Not Cancer Driver No 1 hippie, biogrid 179 1770 71 71 0
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 Not Cancer Driver No 1 intact, hippie 20 0 0 0 0
CTDSP2 CTDSP2 O14595 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 chr12 Not Cancer Driver No 1 hippie 35 18 0 0 0
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 Not Cancer Driver No 1 hippie 78 465 56 56 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 64 102 2 2 0
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 Not Cancer Driver No 3 intact, hippie, biogrid 209 252 77 77 0
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 Not Cancer Driver No 1 intact, hippie 46 382 31 31 0
DCX_ENST00000635795 DCX O43602 Neuronal migration protein doublecortin chrX Not Cancer Driver No 3 intact, hippie, biogrid 118 155 49 49 50
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 biogrid 126 50 8 8 4
DDX20 DDX20 Q9UHI6 Probable ATP-dependent RNA helicase DDX20 chr1 Not Cancer Driver No 1 hippie, biogrid 89 299 33 33 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 Not Cancer Driver No 1 hippie, biogrid 160 441 60 60 0
DGKH DGKH Q86XP1 Diacylglycerol kinase eta chr13 Not Cancer Driver No 1 hippie, biogrid 138 326 43 43 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie, biogrid 62 54 8 8 1
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 37 153 16 16 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie, biogrid 50 174 27 27 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 21 21 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 hippie, biogrid 35 196 26 26 0
DNAJB8_ENST00000319153 DNAJB8 Q8NHS0 DnaJ homolog subfamily B member 8 chr3 Not Cancer Driver No 1 hippie, biogrid 64 92 30 30 0
DNAJC11 DNAJC11 Q9NVH1 DnaJ homolog subfamily C member 11 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 66 123 14 14 0
DNAJC15 DNAJC15 Q9Y5T4 DnaJ homolog subfamily C member 15 chr13 Not Cancer Driver No 1 hippie, biogrid 19 25 4 4 0
DNAJC19 DNAJC19 Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 chr3 Not Cancer Driver No 1 hippie, biogrid 19 27 6 6 0
DNAJC25 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie, biogrid 37 39 3 3 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 25 83 7 7 3
DNAJC4_ENST00000321685 DNAJC4 Q9NNZ3 DnaJ homolog subfamily C member 4 chr11 Not Cancer Driver No 1 hippie, biogrid 19 180 13 13 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie, biogrid 41 102 9 9 0
DNM1 DNM1 Q05193 Dynamin-1 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 98 280 23 23 4
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 3 intact, hippie, biogrid 67 212 23 23 7
DPP6 DPP6 P42658 Dipeptidyl aminopeptidase-like protein 6 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 244 181 45 45 1
DPYSL2_ENST00000311151 DPYSL2 Q16555 Dihydropyrimidinase-related protein 2 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 86 146 32 32 0
DPYSL3_ENST00000398514 DPYSL3 Q14195 Dihydropyrimidinase-related protein 3 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 93 128 14 14 0
DPYSL4 DPYSL4 O14531 Dihydropyrimidinase-related protein 4 chr10 Not Cancer Driver No 1 hippie, biogrid 105 102 15 15 0
DPYSL5 DPYSL5 Q9BPU6 Dihydropyrimidinase-related protein 5 chr2 Not Cancer Driver No 3 hippie, biogrid 132 115 28 28 2
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 intact, hippie 70 273 34 34 0
DUSP21 DUSP21 Q9H596 Dual specificity protein phosphatase 21 chrX Not Cancer Driver No 1 hippie 49 0 0 0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 Not Cancer Driver No 1 hippie 84 0 0 0 0
DUSP23_ENST00000368109 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 Not Cancer Driver No 1 hippie 6 13 1 1 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 Not Cancer Driver No 1 hippie 56 14 6 6 0
DYRK4_ENST00000010132 DYRK4 Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 111 178 33 33 0
ECT2L ECT2L Q008S8 Epithelial cell-transforming sequence 2 oncogene-like chr6 Census Yes 1 hippie, biogrid 131 31 7 7 0
EDIL3 EDIL3 O43854 EGF-like repeat and discoidin I-like domain-containing protein 3 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 135 44 16 16 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF3D EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 Not Cancer Driver No 1 hippie 63 200 26 26 0
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 1 hippie 29 125 8 8 1
ELP1 ELP1 O95163 Elongator complex protein 1 chr9 Not Cancer Driver No 1 hippie 143 157 23 23 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie, biogrid 48 29 3 3 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
EPB41L1 EPB41L1 Q9H4G0 Band 4.1-like protein 1 chr20 Not Cancer Driver No 2 hippie, biogrid 151 577 109 109 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie, biogrid 275 314 41 41 1
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 1 intact, hippie 38 22 3 3 0
ESPL1 ESPL1 Q14674 Separin chr12 Not Cancer Driver No 1 hippie, biogrid 211 380 39 39 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie, biogrid 94 646 93 93 0
FAM13B FAM13B Q9NYF5 Protein FAM13B chr5 Not Cancer Driver No 1 hippie, biogrid 93 575 64 64 0
FBXO25 FBXO25 Q8TCJ0 F-box only protein 25 chr8 Not Cancer Driver No 1 hippie 33 20 0 0 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
FLII FLII Q13045 Protein flightless-1 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 128 206 32 32 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 56 20 3 3 0
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 hippie, biogrid 49 23 2 2 0
GEMIN4 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 101 24 1 1 0
GEMIN6 GEMIN6 Q8WXD5 Gem-associated protein 6 chr2 Not Cancer Driver No 1 hippie, biogrid 19 71 12 12 0
GEMIN7_ENST00000591607 GEMIN7 Q9H840 Gem-associated protein 7 chr19 Not Cancer Driver No 1 hippie, biogrid 32 48 7 7 0
GEMIN8_ENST00000398355 GEMIN8 Q9NWZ8 Gem-associated protein 8 chrX Not Cancer Driver No 1 hippie, biogrid 42 126 29 29 0
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 2 intact, hippie, biogrid 54 10 0 0 15
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 1 hippie, biogrid 57 14 1 1 1
GNAS_ENST00000371075 GNAS O95467 Neuroendocrine secretory protein 55 chr20 Census, Compendium Yes 1 hippie, biogrid 71 221 65 65 0
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 Not Cancer Driver No 3 hippie, biogrid 17 12 3 3 0
GPD2_ENST00000438166 GPD2 P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 3 intact, hippie, biogrid 88 67 7 7 0
GPM6A_ENST00000393658 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 Not Cancer Driver No 3 intact, hippie, biogrid 83 15 5 5 0
GPM6B_ENST00000356942 GPM6B Q13491 Neuronal membrane glycoprotein M6-b chrX Not Cancer Driver No 3 intact, hippie, biogrid 39 14 3 3 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 97 0 0 0 0
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 Not Cancer Driver No 1 hippie, biogrid 83 261 33 33 0
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 Not Cancer Driver No 1 intact, hippie 84 134 27 27 0
GRIA2_ENST00000264426 GRIA2 P42262 Glutamate receptor 2 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 290 50 16 16 14
GRK6_ENST00000355472 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie, biogrid 65 68 10 10 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie, biogrid 56 146 13 13 0
GZMH GZMH P20718 Granzyme H chr14 Not Cancer Driver No 1 hippie, biogrid 47 50 14 14 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 Not Cancer Driver No 1 hippie 103 446 94 94 0
HEATR6 HEATR6 Q6AI08 HEAT repeat-containing protein 6 chr17 Not Cancer Driver No 1 hippie, biogrid 124 250 28 28 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 Not Cancer Driver No 1 hippie 158 565 89 89 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 66 224 66 66 0
HIST1H2BL H2BC13 Q99880 Histone H2B type 1-L chr6 Not Cancer Driver No 1 intact 34 74 20 20 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 Not Cancer Driver No 1 hippie, biogrid 127 75 16 16 6
HNF4G_ENST00000354370 HNF4G Q14541 Hepatocyte nuclear factor 4-gamma chr8 Not Cancer Driver No 1 hippie 122 96 29 29 0
HOXB1 HOXB1 P14653 Homeobox protein Hox-B1 chr17 Not Cancer Driver No 1 hippie, biogrid 71 276 68 68 1
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 Not Cancer Driver No 3 intact, hippie, biogrid 24 42 4 4 3
HPCAL1_ENST00000381765 HPCAL1 P37235 Hippocalcin-like protein 1 chr2 Not Cancer Driver No 3 hippie, biogrid 34 44 9 9 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 2 intact, hippie 336 666 69 69 2
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie, biogrid 669 2091 329 329 21
IFT27 IFT27 Q9BW83 Intraflagellar transport protein 27 homolog chr22 Not Cancer Driver No 1 hippie 14 0 0 0 1
IL1A IL1A P01583 Interleukin-1 alpha chr2 Not Cancer Driver No 3 intact, hippie 30 35 6 6 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 2 hippie, biogrid 45 71 9 9 0
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 intact 190 280 57 57 64
INTS8 INTS8 Q75QN2 Integrator complex subunit 8 chr8 Not Cancer Driver No 1 hippie, biogrid 104 102 10 10 1
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 1 intact, hippie, biogrid 71 337 39 39 0
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie, biogrid 297 798 203 203 0
ITPR2 ITPR2 Q14571 Inositol 1,4,5-trisphosphate receptor type 2 chr12 Not Cancer Driver No 1 hippie, biogrid 359 394 57 57 1
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 intact, hippie 65 173 21 21 3
KIAA0513 KIAA0513 O60268 Uncharacterized protein KIAA0513 chr16 Not Cancer Driver No 1 hippie 66 219 43 43 0
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 Not Cancer Driver No 1 hippie, biogrid 110 337 63 63 0
KMT2C_ENST00000355193 KMT2C Q8NEZ4 Histone-lysine N-methyltransferase 2C chr7 Census, Compendium Yes 1 hippie 835 3599 517 517 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX Not Cancer Driver No 3 intact, hippie, biogrid 228 442 75 75 54
LACTB LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 44 121 3 3 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 47 93 10 10 0
LAS1L LAS1L Q9Y4W2 Ribosomal biogenesis protein LAS1L chrX Not Cancer Driver No 1 hippie, biogrid 100 279 49 49 0
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 3 hippie, biogrid 29 198 24 24 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 intact, hippie, biogrid 178 687 116 116 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 93 146 29 29 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 63 222 25 25 1
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 Not Cancer Driver No 1 intact, hippie 30 1 0 0 0
LRRC49_ENST00000260382 LRRC49 Q8IUZ0 Leucine-rich repeat-containing protein 49 chr15 Not Cancer Driver No 1 hippie, biogrid 117 124 21 21 0
MAGED2 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie, biogrid 99 326 53 53 1
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 Compendium Yes 3 intact, hippie, biogrid 367 1726 340 340 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 Compendium Yes 1 hippie, biogrid 89 144 20 20 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 116 276 41 41 0
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 Not Cancer Driver No 1 hippie 88 107 16 16 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 37 120 16 16 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 3 intact, hippie, biogrid 128 750 126 126 18
MATN4_ENST00000372754 MATN4 O95460 Matrilin-4 chr20 Not Cancer Driver No 1 hippie 148 34 5 5 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie, biogrid 70 411 58 58 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 Not Cancer Driver No 1 hippie, biogrid 59 264 47 47 0
MFSD4A MFSD4A Q8N468 Major facilitator superfamily domain-containing protein 4A chr1 Not Cancer Driver No 1 hippie 56 29 3 3 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie, biogrid 122 282 34 34 1
MICAL3 MICAL3 Q7RTP6 [F-actin]-monooxygenase MICAL3 chr22 Not Cancer Driver No 1 hippie 248 1264 159 159 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 3 hippie, biogrid 40 243 37 37 0
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie 37 187 32 32 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie, biogrid 110 101 8 8 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
MTM1 MTM1 Q13496 Myotubularin chrX Not Cancer Driver No 1 hippie 112 79 9 9 57
MTO1_ENST00000370300 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 70 61 2 2 1
MTR MTR Q99707 Methionine synthase chr1 Not Cancer Driver No 1 hippie, biogrid 151 104 17 17 2
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 Not Cancer Driver No 1 hippie, biogrid 42 43 3 3 0
NAPB_ENST00000377026 NAPB Q9H115 Beta-soluble NSF attachment protein chr20 Not Cancer Driver No 3 intact, hippie, biogrid 30 29 2 2 0
NAPG NAPG Q99747 Gamma-soluble NSF attachment protein chr18 Not Cancer Driver No 1 hippie, biogrid 35 56 3 3 0
NBEAL2 NBEAL2 Q6ZNJ1 Neurobeachin-like protein 2 chr3 Not Cancer Driver No 1 intact, hippie 295 515 59 59 8
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie, biogrid 101 560 51 51 0
NCALD NCALD P61601 Neurocalcin-delta chr8 Not Cancer Driver No 3 intact, hippie, biogrid 37 34 4 4 0
NCAM1_ENST00000316851 NCAM1 P13591 Neural cell adhesion molecule 1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 207 290 70 70 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 1 hippie, biogrid 80 313 45 45 0
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 44 90 11 11 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 Not Cancer Driver No 1 hippie 126 463 60 60 4
NEFL NEFL P07196 Neurofilament light polypeptide chr8 Not Cancer Driver No 1 hippie, biogrid 92 285 39 39 12
NELFCD NELFCD Q8IXH7 Negative elongation factor C/D chr20 Not Cancer Driver No 1 hippie, biogrid 69 53 1 1 0
NISCH_ENST00000479054 NISCH Q9Y2I1 Nischarin chr3 Not Cancer Driver No 1 hippie, biogrid 160 418 43 43 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 Not Cancer Driver No 1 intact, hippie 310 116 43 43 0
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 Not Cancer Driver No 1 hippie, biogrid 73 102 8 8 0
NPAS1_ENST00000449844 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 53 309 23 23 0
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 30 110 5 5 0
NTM_ENST00000374786 NTM Q9P121 Neurotrimin chr11 Not Cancer Driver No 3 intact, hippie, biogrid 126 48 14 14 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 2 intact, hippie 168 57 8 8 25
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 intact 249 57 21 21 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 75 38 4 4 0
NUDT19 NUDT19 A8MXV4 Acyl-coenzyme A diphosphatase NUDT19 chr19 Not Cancer Driver No 1 hippie, biogrid 27 131 5 5 0
NUF2_ENST00000367900 NUF2 Q9BZD4 Kinetochore protein Nuf2 chr1 Not Cancer Driver No 1 hippie, biogrid 97 74 20 20 0
NUP188 NUP188 Q5SRE5 Nucleoporin NUP188 chr9 Not Cancer Driver No 1 hippie, biogrid 190 152 20 20 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 233 553 60 60 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 52 34 4 4 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 114 131 17 17 60
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
PANK4 PANK4 Q9NVE7 4'-phosphopantetheine phosphatase chr1 Not Cancer Driver No 1 hippie, biogrid 92 71 15 15 0
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 49 28 5 5 0
PCNT PCNT O95613 Pericentrin chr21 Not Cancer Driver No 1 hippie, biogrid 436 2474 337 337 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PELO PELO Q9BRX2 Protein pelota homolog chr5 Not Cancer Driver No 1 intact, hippie 38 67 10 10 0
PEX1 PEX1 O43933 Peroxisome biogenesis factor 1 chr7 Not Cancer Driver No 1 hippie, biogrid 143 304 36 36 14
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 1 hippie, biogrid 41 266 38 38 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 Not Cancer Driver No 1 hippie, biogrid 80 70 8 8 9
PGRMC2_ENST00000296425 PGRMC2 O15173 Membrane-associated progesterone receptor component 2 chr4 Not Cancer Driver No 1 hippie, biogrid 16 83 4 4 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 48 50 6 6 4
PI16 PI16 Q6UXB8 Peptidase inhibitor 16 chr6 Not Cancer Driver No 1 hippie 64 256 28 28 0
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 1 hippie, biogrid 267 142 11 11 1
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 93 137 14 14 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie, biogrid 154 268 61 61 2
PKD2 PKD2 Q13563 Polycystin-2 chr4 Not Cancer Driver No 1 intact, hippie 113 375 35 35 10
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 Not Cancer Driver No 1 hippie, biogrid 99 392 49 49 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 Census, Compendium Yes 1 hippie, biogrid 409 239 44 44 3
POLR1D POLR1D P0DPB6 DNA-directed RNA polymerases I and III subunit RPAC2 chr13 Not Cancer Driver No 1 intact, hippie 17 87 13 13 7
POLR2B_ENST00000314595 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 1 hippie, biogrid 166 173 25 25 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 hippie, biogrid 155 113 17 17 15
PPAT PPAT Q06203 Amidophosphoribosyltransferase chr4 Not Cancer Driver No 1 hippie, biogrid 66 48 4 4 0
PPEF1 PPEF1 O14829 Serine/threonine-protein phosphatase with EF-hands 1 chrX Not Cancer Driver No 1 intact, hippie 127 66 10 10 0
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 Not Cancer Driver No 1 intact, hippie 144 130 29 29 0
PPP3CC_ENST00000240139 PPP3CC P48454 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform chr8 Not Cancer Driver No 1 intact, hippie 47 91 7 7 0
PPP3R1 PPP3R1 P63098 Calcineurin subunit B type 1 chr2 Not Cancer Driver No 1 hippie, biogrid 19 1 0 0 0
PRKACG PRKACG P22612 cAMP-dependent protein kinase catalytic subunit gamma chr9 Not Cancer Driver No 1 intact, hippie, biogrid 74 23 7 7 1
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 Not Cancer Driver No 1 hippie 35 25 2 2 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 Not Cancer Driver No 2 intact, hippie, biogrid 60 125 4 4 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 hippie, biogrid 48 51 9 9 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 Not Cancer Driver No 1 intact, hippie 100 135 14 14 0
PTPN14 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 Compendium Yes 1 hippie, biogrid 173 582 99 99 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 51 138 8 8 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 Not Cancer Driver No 1 hippie 141 364 62 62 4
RAB14 RAB14 P61106 Ras-related protein Rab-14 chr9 Not Cancer Driver No 1 hippie, biogrid 20 41 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 Not Cancer Driver No 1 intact, hippie, biogrid 25 43 4 4 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB6A_ENST00000336083 RAB6A P20340 Ras-related protein Rab-6A chr11 Not Cancer Driver No 1 hippie, biogrid 22 45 6 6 0
RAB6B RAB6B Q9NRW1 Ras-related protein Rab-6B chr3 Not Cancer Driver No 3 intact, hippie, biogrid 39 42 5 5 0
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 114 407 40 40 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 2 intact, hippie, biogrid 89 169 38 38 22
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 intact, hippie 10 18 1 1 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 Not Cancer Driver No 1 intact, hippie, biogrid 60 244 26 26 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 intact, hippie 75 400 48 48 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 Not Cancer Driver No 1 hippie, biogrid 38 20 1 1 0
RGS1 RGS1 Q08116 Regulator of G-protein signaling 1 chr1 Not Cancer Driver No 1 hippie 50 45 12 12 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 52 79 5 5 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX Not Cancer Driver No 1 hippie 61 123 15 15 0
RNF217 RNF217 Q8TC41 E3 ubiquitin-protein ligase RNF217 chr6 Not Cancer Driver No 1 hippie 70 203 13 13 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPAP1 RPAP1 Q9BWH6 RNA polymerase II-associated protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 181 448 71 71 0
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 2 intact, hippie 42 243 17 17 0
SCAMP1 SCAMP1 O15126 Secretory carrier-associated membrane protein 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 29 117 14 14 0
SCO1 SCO1 O75880 Protein SCO1 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 35 79 7 7 1
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 1 intact, hippie 184 597 77 77 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 31 29 1 1 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 intact, hippie 63 43 1 1 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 Not Cancer Driver No 1 hippie, biogrid 110 21 7 7 2
SLC25A28 SLC25A28 Q96A46 Mitoferrin-2 chr10 Not Cancer Driver No 1 intact, hippie 43 80 0 0 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 37 96 2 2 4
SLC25A51_ENST00000242275 SLC25A51 Q9H1U9 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 chr9 Not Cancer Driver No 1 hippie, biogrid 31 21 0 0 0
SLC33A1_ENST00000643144 SLC33A1 O00400 Acetyl-coenzyme A transporter 1 chr3 Not Cancer Driver No 1 intact, hippie 64 54 8 8 2
SLC38A10 SLC38A10 Q9HBR0 Putative sodium-coupled neutral amino acid transporter 10 chr17 Not Cancer Driver No 1 hippie, biogrid 128 719 82 82 0
SLCO4A1 SLCO4A1 Q96BD0 Solute carrier organic anion transporter family member 4A1 chr20 Not Cancer Driver No 1 hippie, biogrid 106 66 5 5 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 hippie 2 181 2 2 0
SMN2_ENST00000380741 SMN2 Q16637 Survival motor neuron protein chr5 Not Cancer Driver No 1 biogrid 1 220 1 1 18
SMPD4 SMPD4 Q9NXE4 Sphingomyelin phosphodiesterase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 114 80 12 12 1
SNAP47_ENST00000366759 SNAP47 Q5SQN1 Synaptosomal-associated protein 47 chr1 Not Cancer Driver No 1 hippie, biogrid 51 192 20 20 0
SNAP91_ENST00000369694 SNAP91 O60641 Clathrin coat assembly protein AP180 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 203 636 118 118 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 2 hippie, biogrid 21 107 13 13 5
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 Not Cancer Driver No 1 hippie 81 299 48 48 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SRMS SRMS Q9H3Y6 Tyrosine-protein kinase Srms chr20 Not Cancer Driver No 1 intact, hippie, biogrid 77 48 11 11 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 Not Cancer Driver No 1 hippie 129 658 85 85 0
STARD8_ENST00000374597 STARD8 Q92502 StAR-related lipid transfer protein 8 chrX Not Cancer Driver No 1 hippie, biogrid 145 574 86 86 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 Census, Compendium Yes 1 intact, hippie 93 144 19 19 5
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 74 270 39 39 0
STPG3 STPG3 Q8N7X2 Protein STPG3 chr9 Not Cancer Driver No 1 hippie 23 309 20 20 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie, biogrid 35 112 14 14 12
STX17_ENST00000534052 STX17 P56962 Syntaxin-17 chr9 Not Cancer Driver No 1 hippie, biogrid 27 81 4 4 0
STX1A STX1A Q16623 Syntaxin-1A chr7 Not Cancer Driver No 3 intact, hippie, biogrid 35 136 11 11 0
STX1B STX1B P61266 Syntaxin-1B chr16 Not Cancer Driver No 3 hippie, biogrid 38 155 20 20 2
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 97 111 23 23 18
SULT1C4 SULT1C4 O75897 Sulfotransferase 1C4 chr2 Not Cancer Driver No 1 hippie, biogrid 57 19 5 5 0
SURF1 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 17 82 6 6 11
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 intact, hippie 308 1423 192 192 0
SYN1 SYN1 P17600 Synapsin-1 chrX Not Cancer Driver No 3 intact, hippie, biogrid 75 445 27 27 0
SYN2 SYN2 Q92777 Synapsin-2 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 56 295 21 21 0
SYP SYP P08247 Synaptophysin chrX Not Cancer Driver No 1 hippie, biogrid 36 93 8 8 1
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 Not Cancer Driver No 3 hippie, biogrid 104 103 36 36 5
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX Not Cancer Driver No 1 hippie 379 1152 219 219 5
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 intact, hippie 42 302 26 26 0
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 112 53 10 10 1
TBC1D32 TBC1D32 Q96NH3 Protein broad-minded chr6 Not Cancer Driver No 1 hippie 173 110 19 19 0
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 113 154 23 23 5
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie, biogrid 68 169 23 23 0
TIMM29 TIMM29 Q9BSF4 Mitochondrial import inner membrane translocase subunit Tim29 chr19 Not Cancer Driver No 1 hippie 9 4 0 0 0
TMEM263_ENST00000551813 TMEM263 Q8WUH6 Transmembrane protein 263 chr12 Not Cancer Driver No 1 hippie, biogrid 6 63 3 3 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact, hippie 58 111 15 15 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 intact, hippie 48 229 28 28 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 Not Cancer Driver No 1 hippie, biogrid 58 18 1 1 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 Not Cancer Driver No 1 hippie 137 593 81 81 0
TOX3 TOX3 O15405 TOX high mobility group box family member 3 chr16 Not Cancer Driver No 1 hippie, biogrid 85 485 72 72 0
TPCN1_ENST00000335509 TPCN1 Q9ULQ1 Two pore channel protein 1 chr12 Not Cancer Driver No 1 intact, hippie 114 99 18 18 0
TPCN2 TPCN2 Q8NHX9 Two pore channel protein 2 chr11 Not Cancer Driver No 1 intact, hippie 73 16 0 0 0
TRABD_ENST00000395827 TRABD Q9H4I3 TraB domain-containing protein chr22 Not Cancer Driver No 1 hippie, biogrid 38 66 6 6 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRMU TRMU O75648 Mitochondrial tRNA-specific 2-thiouridylase 1 chr22 Not Cancer Driver No 1 hippie, biogrid 40 28 5 5 2
TSC2 TSC2 P49815 Tuberin chr16 Census, Compendium Yes 1 hippie, biogrid 192 563 50 50 53
TSC22D1 TSC22D1 Q15714 TSC22 domain family protein 1 chr13 Not Cancer Driver No 1 intact, hippie 110 1023 98 98 0
TSSK6 TSSK6 Q9BXA6 Testis-specific serine/threonine-protein kinase 6 chr19 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 0
TTC37 TTC37 Q6PGP7 Tetratricopeptide repeat protein 37 chr5 Not Cancer Driver No 1 hippie, biogrid 164 59 3 3 3
TTC3_ENST00000355666 TTC3 P53804 E3 ubiquitin-protein ligase TTC3 chr21 Not Cancer Driver No 1 hippie, biogrid 255 723 83 83 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 3 intact, hippie, biogrid 59 52 11 11 8
TUBA1C_ENST00000301072 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 intact, hippie 39 50 5 5 0
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 hippie 91 61 16 16 2
TUBGCP2_ENST00000368563 TUBGCP2 Q9BSJ2 Gamma-tubulin complex component 2 chr10 Not Cancer Driver No 1 hippie 124 93 16 16 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie 109 156 16 16 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 Not Cancer Driver No 1 intact 119 197 17 17 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 1 hippie, biogrid 20 102 8 8 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
USP30 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 Not Cancer Driver No 1 hippie, biogrid 76 136 26 26 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS13A VPS13A Q96RL7 Intermembrane lipid transfer protein VPS13A chr9 Not Cancer Driver No 1 hippie, biogrid 375 208 18 18 6
VPS13B VPS13B Q7Z7G8 Intermembrane lipid transfer protein VPS13B chr8 Not Cancer Driver No 1 hippie, biogrid 660 635 106 106 5
VSNL1_ENST00000404666 VSNL1 P62760 Visinin-like protein 1 chr2 Not Cancer Driver No 3 hippie, biogrid 28 15 3 3 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 Not Cancer Driver No 1 hippie, biogrid 181 792 100 100 5
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 hippie, biogrid 166 105 13 13 0
WRAP73 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 Not Cancer Driver No 1 hippie, biogrid 50 5 0 0 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 1 hippie 89 55 6 6 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 Not Cancer Driver No 1 intact, hippie 24 35 2 2 1
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 Not Cancer Driver No 1 hippie, biogrid 19 21 2 2 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 Not Cancer Driver No 1 intact, hippie 112 136 14 14 1
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact, hippie 26 77 9 9 2
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
ZNF420 ZNF420 Q8TAQ5 Zinc finger protein 420 chr19 Not Cancer Driver No 1 intact, hippie 110 154 24 24 0
ZNRD1 POLR1H Q9P1U0 DNA-directed RNA polymerase I subunit RPA12 chr6 Not Cancer Driver No 1 intact 6 14 1 1 0
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 1 hippie 115 99 26 26 0