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GNG5_ENST00000370645 ,GNG5 ,P63218
  • Uniprot Accession= P63218
  • Ensembl Transcript= ENST00000370645.8
  • Uniprot Name= GNG5
  • Name= Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 50
  • Number of Interaction partner in hippie: 66
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 74 36 6 6 0
AGPS AGPS O00116 Alkyldihydroxyacetonephosphate synthase, peroxisomal chr2 Not Cancer Driver No 1 hippie, biogrid 68 151 10 10 6
AMOTL2_ENST00000422605 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 Not Cancer Driver No 1 hippie 94 741 93 93 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
C1QL4 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 19 101 5 5 0
CARNMT1 CARNMT1 Q8N4J0 Carnosine N-methyltransferase chr9 Not Cancer Driver No 1 hippie 42 75 1 1 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
COX7A2L COX7A2L O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
CYB5R1 CYB5R1 Q9UHQ9 NADH-cytochrome b5 reductase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 43 22 1 1 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 42 24 3 3 9
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 84 0 0 0 0
EPS15 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 Census, Compendium Yes 1 intact 106 543 66 66 0
EPS15L1_ENST00000248070 EPS15L1 Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 chr19 Not Cancer Driver No 1 hippie 109 603 76 76 0
FSD1 FSD1 Q9BTV5 Fibronectin type III and SPRY domain-containing protein 1 chr19 Not Cancer Driver No 2 hippie, biogrid 66 90 17 17 0
FYTTD1 FYTTD1 Q96QD9 UAP56-interacting factor chr3 Not Cancer Driver No 2 hippie, biogrid 51 281 48 48 0
GNA11 GNA11 P29992 Guanine nucleotide-binding protein subunit alpha-11 chr19 Census, Compendium Yes 1 hippie, biogrid 48 10 0 0 5
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 Compendium Yes 1 hippie, biogrid 52 32 4 4 0
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 52 11 3 3 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 Compendium Yes 3 intact, hippie, biogrid 50 24 0 0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 42 11 0 0 1
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 1 hippie, biogrid 57 14 1 1 1
GNAS_ENST00000371075 GNAS O95467 Neuroendocrine secretory protein 55 chr20 Census, Compendium Yes 3 hippie, biogrid 71 221 65 65 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 45 24 2 2 16
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 50 21 0 0 7
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 Not Cancer Driver No 2 hippie, biogrid 51 13 1 1 0
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 2 hippie, biogrid 49 27 3 3 2
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 Not Cancer Driver No 2 hippie, biogrid 60 16 1 1 1
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 intact, hippie 115 854 96 96 0
GULP1 GULP1 Q9UBP9 PTB domain-containing engulfment adapter protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 38 148 19 19 0
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 72 19 2 2 5
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 41 9 9 14
IER3IP1 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 3 0 0 0 2
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
KRT40_ENST00000398486 KRT40 Q6A162 Keratin, type I cytoskeletal 40 chr17 Not Cancer Driver No 1 intact, hippie 70 6 1 1 0
MAIP1 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 28 12 0 0 0
MDFI MDFI Q99750 MyoD family inhibitor chr6 Not Cancer Driver No 1 hippie 25 152 15 15 0
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
NDUFA3 NDUFA3 O95167 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 chr19 Not Cancer Driver No 1 hippie, biogrid 7 27 4 4 0
NDUFA8 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 1 hippie, biogrid 25 33 1 1 2
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 2 intact, hippie, biogrid 37 102 9 9 1
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OCIAD2 OCIAD2 Q56VL3 OCIA domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 21 27 4 4 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie, biogrid 150 106 19 19 0
PDCL PDCL Q13371 Phosducin-like protein chr9 Not Cancer Driver No 1 hippie, biogrid 33 146 13 13 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PMS1 PMS1 P54277 PMS1 protein homolog 1 chr2 Census Yes 1 intact, hippie, biogrid 114 283 38 38 0
PPP1R3C PPP1R3C Q9UQK1 Protein phosphatase 1 regulatory subunit 3C chr10 Not Cancer Driver No 2 intact, hippie, biogrid 37 16 0 0 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 23 23 3 3 0
PREB PREB Q9HCU5 Prolactin regulatory element-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 56 91 10 10 0
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 Not Cancer Driver No 1 hippie 74 144 25 25 0
PTGES2 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 Not Cancer Driver No 1 hippie, biogrid 30 30 1 1 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 16 38 2 2 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 4
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 86 29 6 6 0
SCCPDH SCCPDH Q8NBX0 Saccharopine dehydrogenase-like oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 56 26 1 1 0
SERP2 SERP2 Q8N6R1 Stress-associated endoplasmic reticulum protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 4 22 0 0 0
SLC25A20 SLC25A20 O43772 Mitochondrial carnitine/acylcarnitine carrier protein chr3 Not Cancer Driver No 1 hippie, biogrid 39 17 3 3 3
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 49 32 4 4 1
SLC25A41 SLC25A41 Q8N5S1 Mitochondrial carrier protein SCaMC-3L chr19 Not Cancer Driver No 3 hippie, biogrid 54 59 7 7 0
SLC6A5 SLC6A5 Q9Y345 Sodium- and chloride-dependent glycine transporter 2 chr11 Not Cancer Driver No 1 hippie, biogrid 181 169 38 38 7
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 73 228 43 43 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 intact, hippie 51 63 9 9 0
UXS1_ENST00000409501 UXS1 Q8NBZ7 UDP-glucuronic acid decarboxylase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 70 69 9 9 0
VDAC3_ENST00000022615 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0