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GNG12 ,GNG12 ,Q9UBI6
  • Uniprot Accession= Q9UBI6
  • Ensembl Transcript= ENST00000370982.3
  • Uniprot Name= GNG12
  • Name= Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 81
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 hippie, biogrid 74 311 43 43 0
BCKDK BCKDK O14874 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 62 39 3 3 3
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 intact, hippie 94 75 21 21 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 Not Cancer Driver No 1 hippie 68 32 2 2 1
CAT CAT P04040 Catalase chr11 Not Cancer Driver No 1 intact, hippie 70 176 18 18 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDKL2_ENST00000429927 CDKL2 Q92772 Cyclin-dependent kinase-like 2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 63 171 21 21 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 intact, hippie 48 121 30 30 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 59 17 3 3 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 56 5 2 2 0
CLUAP1_ENST00000576634 CLUAP1 Q96AJ1 Clusterin-associated protein 1 chr16 Not Cancer Driver No 1 hippie 48 203 22 22 0
COPE_ENST00000262812 COPE O14579 Coatomer subunit epsilon chr19 Not Cancer Driver No 1 hippie 29 47 6 6 0
CSNK1G1 CSNK1G1 Q9HCP0 Casein kinase I isoform gamma-1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 52 130 15 15 0
CYB5A CYB5A P00167 Cytochrome b5 chr18 Not Cancer Driver No 1 hippie, biogrid 20 70 12 12 1
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 Not Cancer Driver No 1 intact, hippie 43 63 9 9 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 Census Yes 1 hippie 77 27 14 14 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact 147 211 38 38 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM160B1 FHIP2A Q5W0V3 FHF complex subunit HOOK interacting protein 2A chr10 Not Cancer Driver No 1 intact 92 130 13 13 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 56 20 3 3 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 Compendium Yes 1 hippie, biogrid 52 32 4 4 0
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 1 hippie, biogrid 57 14 1 1 1
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 Not Cancer Driver No 1 hippie 45 24 2 2 16
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 hippie 50 21 0 0 7
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 Not Cancer Driver No 1 hippie 51 13 1 1 0
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 1 hippie 49 27 3 3 2
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 intact, hippie, biogrid 56 146 13 13 0
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 87 373 36 36 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 intact, hippie 91 570 50 50 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
INSRR INSRR P14616 Insulin receptor-related protein chr1 Not Cancer Driver No 1 intact 262 228 37 37 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 13 204 8 8 0
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 Not Cancer Driver No 1 hippie, biogrid 50 4 0 0 1
MED20 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 1 hippie 22 0 0 0 0
MED23 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 1 intact, hippie 158 28 2 2 1
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 Not Cancer Driver No 1 hippie 62 454 56 56 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 226 62 15 15 19
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 58 143 16 16 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
NIPSNAP2 NIPSNAP2 O75323 Protein NipSnap homolog 2 chr7 Not Cancer Driver No 1 hippie 30 6 1 1 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PDCL PDCL Q13371 Phosducin-like protein chr9 Not Cancer Driver No 1 hippie, biogrid 33 146 13 13 0
PFKFB4 PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 chr3 Not Cancer Driver No 1 hippie, biogrid 71 44 3 3 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 24 9 0 0 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 78 58 13 13 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 Not Cancer Driver No 1 hippie, biogrid 27 5 0 0 0
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 52 19 2 2 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 66 295 39 39 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 Not Cancer Driver No 1 hippie, biogrid 141 297 18 18 8
TBP TBP P20226 TATA-box-binding protein chr6 Not Cancer Driver No 1 hippie 40 164 14 14 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 102 151 17 17 0
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 50 52 3 3 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZNF518A ZNF518A Q6AHZ1 Zinc finger protein 518A chr10 Not Cancer Driver No 1 intact, hippie 151 717 80 80 0