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GNB1_ENST00000378609 ,GNB1 ,P62873
  • Uniprot Accession= P62873
  • Ensembl Transcript= ENST00000378609.8
  • Uniprot Name= GNB1
  • Name= Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 60
  • Number of Interaction partner in biogrid: 66
  • Number of Interaction partner in hippie: 233
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 Not Cancer Driver No 1 intact, hippie 40 157 20 20 0
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 74 36 6 6 0
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie 94 172 19 19 5
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 Not Cancer Driver No 1 hippie 67 161 10 10 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
AFP AFP P02771 Alpha-fetoprotein chr4 Not Cancer Driver No 1 hippie 107 24 5 5 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 hippie 77 84 9 9 2
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARHGEF18_ENST00000319670 ARHGEF18 Q6ZSZ5-2 Isoform 4 of Rho guanine nucleotide exchange factor 18 chr19 Not Cancer Driver No 1 hippie 120 610 58 58 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 hippie 205 1300 174 174 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie 86 31 2 2 4
ATP6V1B1 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 Not Cancer Driver No 1 hippie 77 66 14 14 9
ATXN10 ATXN10 Q9UBB4 Ataxin-10 chr22 Not Cancer Driver No 1 hippie 46 37 2 2 0
AVPR2_ENST00000337474 AVPR2 P30518 Vasopressin V2 receptor chrX Not Cancer Driver No 1 hippie 58 56 7 7 84
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 147 114 27 27 110
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 Not Cancer Driver No 1 hippie 436 1144 132 132 46
CACNA1B CACNA1B Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B chr9 Not Cancer Driver No 1 hippie 416 917 115 115 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 Not Cancer Driver No 1 hippie 455 744 146 146 14
CALCA_ENST00000361010 CALCA P06881 Calcitonin gene-related peptide 1 chr11 Not Cancer Driver No 1 intact, hippie 25 44 11 11 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 Not Cancer Driver No 1 intact, hippie 162 29 9 9 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 Not Cancer Driver No 1 hippie, biogrid 101 127 30 30 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 hippie, biogrid 63 46 3 3 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 71 95 12 12 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 1 hippie, biogrid 51 92 2 2 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 2 hippie, biogrid 83 72 10 10 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 hippie, biogrid 66 5 1 1 0
CCT6B CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 Not Cancer Driver No 1 hippie, biogrid 90 1 0 0 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie, biogrid 59 36 6 6 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 Not Cancer Driver No 1 hippie 71 79 26 26 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDKL2_ENST00000429927 CDKL2 Q92772 Cyclin-dependent kinase-like 2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 63 171 21 21 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 68 278 40 40 0
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 287 145 18 18 151
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHRM4 CHRM4 P08173 Muscarinic acetylcholine receptor M4 chr11 Not Cancer Driver No 1 intact, hippie 75 143 27 27 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 59 17 3 3 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 56 5 2 2 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 48 0 0 0 2
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
CSNK1G1 CSNK1G1 Q9HCP0 Casein kinase I isoform gamma-1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 52 130 15 15 0
CSNK1G2 CSNK1G2 P78368 Casein kinase I isoform gamma-2 chr19 Not Cancer Driver No 1 hippie, biogrid 43 111 13 13 0
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CTNNA3 CTNNA3 Q9UI47 Catenin alpha-3 chr10 Not Cancer Driver No 1 intact, hippie 269 186 50 50 1
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 42 24 3 3 9
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 Not Cancer Driver No 1 hippie 46 96 0 0 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 2 intact, hippie 132 514 82 82 0
DPF1_ENST00000456296 DPF1 Q92782 Zinc finger protein neuro-d4 chr19 Not Cancer Driver No 1 intact, hippie 32 85 7 7 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 Not Cancer Driver No 1 hippie 127 124 45 45 0
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX Not Cancer Driver No 1 hippie 40 109 12 12 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 Census, Compendium Yes 1 intact 346 74 28 28 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 intact, hippie 280 71 15 15 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 Not Cancer Driver No 1 hippie 90 35 7 7 4
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FAM160B2 FHIP2B Q86V87 FHF complex subunit HOOK interacting protein 2B chr8 Not Cancer Driver No 1 intact 75 139 14 14 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 152 230 43 43 74
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX Not Cancer Driver No 1 hippie 56 51 7 7 13
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
FRK FRK P42685 Tyrosine-protein kinase FRK chr6 Not Cancer Driver No 1 hippie, biogrid 87 18 2 2 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 Not Cancer Driver No 1 hippie 150 142 17 17 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 206 1015 184 184 0
GNA11 GNA11 P29992 Guanine nucleotide-binding protein subunit alpha-11 chr19 Census, Compendium Yes 2 hippie, biogrid 48 10 0 0 5
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 Not Cancer Driver No 1 hippie 41 20 0 0 0
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 Not Cancer Driver No 4 intact, hippie, biogrid 52 11 3 3 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 Compendium Yes 4 intact, hippie, biogrid 50 24 0 0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 5 intact, hippie, biogrid 42 11 0 0 1
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 54 10 0 0 15
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 2 hippie, biogrid 57 14 1 1 1
GNAS_ENST00000371075 GNAS O95467 Neuroendocrine secretory protein 55 chr20 Census, Compendium Yes 4 hippie, biogrid 71 221 65 65 0
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 Not Cancer Driver No 3 intact 43 39 6 6 3
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 hippie, biogrid 50 21 0 0 7
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 Not Cancer Driver No 1 hippie, biogrid 51 13 1 1 0
GNG10 GNG10 P50151 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 chr9 Not Cancer Driver No 2 hippie, biogrid 5 0 0 0 0
GNG11 GNG11 P61952 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 chr7 Not Cancer Driver No 1 hippie 14 66 13 13 0
GNG12 GNG12 Q9UBI6 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 chr1 Not Cancer Driver No 1 hippie 10 26 5 5 0
GNG13 GNG13 Q9P2W3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 chr16 Not Cancer Driver No 1 hippie 17 12 2 2 0
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 17 12 3 3 0
GNG3 GNG3 P63215 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 10 20 1 1 0
GNG4 GNG4 P50150 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 21 22 2 2 0
GNG5_ENST00000370645 GNG5 P63218 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 5 9 1 1 0
GNG7 GNG7 O60262 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 chr19 Not Cancer Driver No 2 hippie, biogrid 13 10 1 1 0
GNG8 GNG8 Q9UK08 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 chr19 Not Cancer Driver No 2 hippie, biogrid 2 16 1 1 0
GNGT1_ENST00000429473 GNGT1 P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 chr7 Not Cancer Driver No 6 intact, hippie, biogrid 14 25 4 4 0
GNGT2_ENST00000511673 GNGT2 O14610 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 chr17 Not Cancer Driver No 1 hippie 15 65 14 14 0
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 Not Cancer Driver No 2 intact, hippie 77 87 8 8 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 intact, hippie, biogrid 56 146 13 13 0
HACD1 HACD1 B0YJ81 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 chr10 Not Cancer Driver No 1 intact, hippie 74 63 21 21 0
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 41 9 9 14
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 87 373 36 36 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact 94 487 62 62 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 27 15 3 3 11
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie, biogrid 149 251 52 52 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 Not Cancer Driver No 1 intact, hippie 91 33 15 15 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 2 intact, hippie 336 666 69 69 2
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KALRN_ENST00000360013 KALRN O60229 Kalirin chr3 Not Cancer Driver No 1 hippie 544 732 128 128 0
KCNJ3 KCNJ3 P48549 G protein-activated inward rectifier potassium channel 1 chr2 Not Cancer Driver No 1 hippie 189 162 64 64 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 114 404 58 58 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 intact, hippie 22 0 0 0 1
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 Not Cancer Driver No 1 hippie 173 410 54 54 0
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX Not Cancer Driver No 1 hippie 218 124 33 33 0
MED9 MED9 Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 chr17 Not Cancer Driver No 1 hippie 16 127 15 15 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 intact 226 62 15 15 19
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 1 hippie 40 243 37 37 0
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie 37 187 32 32 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRGPRX1 MRGPRX1 Q96LB2 Mas-related G-protein coupled receptor member X1 chr11 Not Cancer Driver No 1 hippie 123 0 0 0 0
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 Not Cancer Driver No 1 intact 178 182 27 27 1
MTFR1 MTFR1 Q15390 Mitochondrial fission regulator 1 chr8 Not Cancer Driver No 1 hippie, biogrid 41 230 27 27 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 Not Cancer Driver No 2 intact, hippie 72 0 0 0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 1 hippie 104 8 1 1 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 Census, Compendium Yes 1 hippie 379 296 37 37 18
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 Not Cancer Driver No 1 hippie 97 183 34 34 14
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 Not Cancer Driver No 1 intact, hippie 76 54 9 9 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie, biogrid 146 211 31 31 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDCD3 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 intact, hippie 30 199 16 16 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 intact, hippie 61 79 15 15 1
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 57 299 30 30 2
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PAQR3 PAQR3 Q6TCH7 Progestin and adipoQ receptor family member 3 chr4 Not Cancer Driver No 1 hippie 38 0 0 0 0
PATJ PATJ Q8NI35 InaD-like protein chr1 Not Cancer Driver No 1 intact, hippie 261 918 142 142 0
PDCL PDCL Q13371 Phosducin-like protein chr9 Not Cancer Driver No 2 hippie, biogrid 33 146 13 13 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 intact 290 173 45 45 2
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 48 244 20 20 0
PFDN1 PFDN1 O60925 Prefoldin subunit 1 chr5 Not Cancer Driver No 1 hippie, biogrid 8 42 4 4 0
PFDN5 PFDN5 Q99471 Prefoldin subunit 5 chr12 Not Cancer Driver No 2 hippie, biogrid 18 3 0 0 0
PGAM2 PGAM2 P15259 Phosphoglycerate mutase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 46 81 14 14 3
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1 hippie 1669 38 11 11 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 Census, Compendium Yes 1 hippie 150 42 4 4 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 24 9 0 0 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PLEKHG2 PLEKHG2 Q9H7P9 Pleckstrin homology domain-containing family G member 2 chr19 Not Cancer Driver No 1 hippie 168 1053 139 139 1
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
PPIE_ENST00000324379 PPIE Q9UNP9 Peptidyl-prolyl cis-trans isomerase E chr1 Not Cancer Driver No 1 hippie 51 102 17 17 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 26 23 4 4 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 205 148 40 40 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
PSMB9 PSMB9 P28065 Proteasome subunit beta type-9 chr6 Not Cancer Driver No 1 intact, hippie 21 17 1 1 1
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 Not Cancer Driver No 1 intact, hippie 100 135 14 14 0
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 Not Cancer Driver No 1 hippie 86 124 25 25 5
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 hippie 134 425 55 55 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RADIL RADIL Q96JH8 Ras-associating and dilute domain-containing protein chr7 Not Cancer Driver No 1 hippie 173 381 62 62 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 Not Cancer Driver No 1 hippie 27 5 0 0 0
RASD1 RASD1 Q9Y272 Dexamethasone-induced Ras-related protein 1 chr17 Not Cancer Driver No 1 hippie 24 40 1 1 0
RASD2 RASD2 Q96D21 GTP-binding protein Rhes chr22 Not Cancer Driver No 1 hippie 59 14 2 2 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RGS6_ENST00000553530 RGS6 P49758 Regulator of G-protein signaling 6 chr14 Not Cancer Driver No 1 hippie 118 61 21 21 0
RHO RHO P08100 Rhodopsin chr3 Not Cancer Driver No 1 intact 68 18 3 3 69
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 hippie 212 366 50 50 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 66 295 39 39 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 Census, Compendium Yes 1 hippie 560 623 75 75 3
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SAMM50 SAMM50 Q9Y512 Sorting and assembly machinery component 50 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 51 34 1 1 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SMO SMO Q99835 Smoothened homolog chr7 Census, Compendium Yes 1 hippie 112 241 27 27 1
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 biogrid 89 256 31 31 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 16 93 9 9 79
SPAG1_ENST00000251809 SPAG1 Q07617 Sperm-associated antigen 1 chr8 Not Cancer Driver No 1 hippie 106 385 46 46 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie 308 1423 192 192 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 63 284 32 32 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 Not Cancer Driver No 1 intact, hippie, biogrid 115 88 9 9 2
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 Not Cancer Driver No 1 hippie 47 17 4 4 1
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 54 55 10 10 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 Not Cancer Driver No 1 hippie 67 153 16 16 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 1 hippie, biogrid 103 53 18 18 13
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 50 52 3 3 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UQCRB_ENST00000287022 UQCRB P14927 Cytochrome b-c1 complex subunit 7 chr8 Not Cancer Driver No 1 hippie 28 2 1 1 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
VAC14 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 1 hippie 97 116 19 19 3
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 188 110 28 28 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 35 9 1 1 0
VDAC3_ENST00000022615 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR26 WDR26 Q9H7D7 WD repeat-containing protein 26 chr1 Not Cancer Driver No 1 hippie 71 187 9 9 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0