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GNAI3 ,GNAI3 ,P08754
  • Uniprot Accession= P08754
  • Ensembl Transcript= ENST00000369851.5
  • Uniprot Name= GNAI3
  • Name= Guanine nucleotide-binding protein G(i) subunit alpha-3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 58
  • Number of Interaction partner in biogrid: 70
  • Number of Interaction partner in hippie: 197
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAAS AAAS Q9NRG9 Aladin chr12 Not Cancer Driver No 1 hippie, biogrid 58 116 12 12 3
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 1 hippie, biogrid 104 68 5 5 0
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 Census, Compendium Yes 1 hippie, biogrid 98 56 6 6 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
ADSL ADSL P30566 Adenylosuccinate lyase chr22 Not Cancer Driver No 1 hippie 68 36 9 9 27
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX Not Cancer Driver No 1 hippie 98 0 0 0 0
ALG6 ALG6 Q9Y672 Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase chr1 Not Cancer Driver No 1 hippie, biogrid 42 1 0 0 6
ANKRD13B ANKRD13B Q86YJ7 Ankyrin repeat domain-containing protein 13B chr17 Not Cancer Driver No 3 intact, hippie, biogrid 64 290 18 18 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
API5 API5 Q9BZZ5 Apoptosis inhibitor 5 chr11 Not Cancer Driver No 1 hippie 65 92 10 10 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact 228 887 124 124 0
ATP12A_ENST00000381946 ATP12A P54707 Potassium-transporting ATPase alpha chain 2 chr13 Not Cancer Driver No 1 hippie 203 117 24 24 0
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 130 147 16 16 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie, biogrid 168 341 64 64 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BCKDK BCKDK O14874 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 62 39 3 3 3
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
BZW1_ENST00000409600 BZW1 Q7L1Q6 eIF5-mimic protein 2 chr2 Not Cancer Driver No 1 hippie 43 49 8 8 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 Not Cancer Driver No 1 hippie 71 0 0 0 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 1 hippie 30 58 5 5 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 Not Cancer Driver No 1 hippie, biogrid 226 1481 173 173 0
CCDC88C CCDC88C Q9P219 Protein Daple chr14 Not Cancer Driver No 2 intact, hippie 270 1604 225 225 1
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 Not Cancer Driver No 1 hippie, biogrid 85 495 61 61 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 Not Cancer Driver No 1 hippie 107 0 0 0 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 Not Cancer Driver No 1 hippie 71 79 26 26 0
CD48_ENST00000368046 CD48 P09326 CD48 antigen chr1 Not Cancer Driver No 1 hippie 39 2 0 0 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 Not Cancer Driver No 1 hippie, biogrid 45 128 13 13 1
CD59_ENST00000395850 CD59 P13987 CD59 glycoprotein chr11 Not Cancer Driver No 1 hippie 18 0 0 0 1
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CDV3 CDV3 Q9UKY7 Protein CDV3 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 16 258 16 16 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 59 17 3 3 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 56 5 2 2 0
CLTCL1 CLTCL1 P53675 Clathrin heavy chain 2 chr22 Census, Compendium Yes 3 intact, hippie, biogrid 210 10 1 1 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 Not Cancer Driver No 1 hippie 129 9 1 1 0
CSNK1G1 CSNK1G1 Q9HCP0 Casein kinase I isoform gamma-1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 52 130 15 15 0
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 47 34 4 4 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 Not Cancer Driver No 1 hippie 87 8 0 0 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 18 7 0 0 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 Not Cancer Driver No 1 hippie 127 124 45 45 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 Not Cancer Driver No 1 hippie 84 0 0 0 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 Not Cancer Driver No 1 hippie 43 39 3 3 4
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX Not Cancer Driver No 1 hippie 40 109 12 12 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 Not Cancer Driver No 1 hippie 73 434 38 38 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 54 141 5 5 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF5_ENST00000392715 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 Not Cancer Driver No 1 hippie 64 185 23 23 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 intact 182 140 24 24 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FSCN1 FSCN1 Q16658 Fascin chr7 Not Cancer Driver No 1 hippie 58 81 5 5 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 Not Cancer Driver No 1 hippie, biogrid 93 283 35 35 0
FZD7 FZD7 O75084 Frizzled-7 chr2 Not Cancer Driver No 1 hippie 90 22 2 2 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact 85 352 65 65 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie 79 570 68 68 1
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 Not Cancer Driver No 4 intact, hippie, biogrid 52 11 3 3 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 Compendium Yes 4 intact, hippie, biogrid 50 24 0 0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie 42 11 0 0 1
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 3 intact, hippie, biogrid 54 10 0 0 15
GNAT2 GNAT2 P19087 Guanine nucleotide-binding protein G(t) subunit alpha-2 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 38 44 7 7 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 Not Cancer Driver No 5 intact, hippie, biogrid 45 24 2 2 16
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 4 intact, hippie, biogrid 50 21 0 0 7
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 Not Cancer Driver No 1 hippie 51 13 1 1 0
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 4 intact, hippie, biogrid 49 27 3 3 2
GNG10 GNG10 P50151 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 5 0 0 0 0
GNG11 GNG11 P61952 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 14 66 13 13 0
GNG3 GNG3 P63215 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 chr11 Not Cancer Driver No 1 intact, hippie 10 20 1 1 0
GNG4 GNG4 P50150 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 21 22 2 2 0
GNG5_ENST00000370645 GNG5 P63218 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 5 9 1 1 0
GNG7 GNG7 O60262 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 13 10 1 1 0
GPSM1 GPSM1 Q86YR5 G-protein-signaling modulator 1 chr9 Not Cancer Driver No 3 hippie, biogrid 68 344 35 35 0
GPSM2_ENST00000642355 GPSM2 P81274 G-protein-signaling modulator 2 chr1 Not Cancer Driver No 2 intact, hippie 79 240 21 21 0
GPSM3_ENST00000375043 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 Not Cancer Driver No 1 hippie 26 160 26 26 0
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 Not Cancer Driver No 1 intact, hippie 91 660 85 85 0
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 87 373 36 36 0
HTR1A HTR1A P08908 5-hydroxytryptamine receptor 1A chr5 Not Cancer Driver No 1 hippie 170 100 49 49 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 hippie, biogrid 788 7 2 2 27
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 114 404 58 58 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie 40 9 0 0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie 47 15 2 2 11
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 Not Cancer Driver No 1 hippie 79 21 6 6 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAN1B1 MAN1B1 Q9UKM7 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase chr9 Not Cancer Driver No 1 hippie, biogrid 74 172 22 22 2
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MMGT1 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 1 hippie 24 17 4 4 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 Not Cancer Driver No 3 intact, hippie 72 0 0 0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 2 intact, hippie 104 8 1 1 0
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie 101 560 51 51 0
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 Not Cancer Driver No 1 hippie 97 183 34 34 14
NDC1 NDC1 Q9BTX1 Nucleoporin NDC1 chr1 Not Cancer Driver No 3 hippie, biogrid 62 92 12 12 0
NDUFS5_ENST00000372967 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 Not Cancer Driver No 1 hippie 15 31 3 3 0
NGB NGB Q9NPG2 Neuroglobin chr14 Not Cancer Driver No 1 hippie 20 3 0 0 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie, biogrid 146 211 31 31 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 2 intact, hippie 168 57 8 8 25
NUCB1 NUCB1 Q02818 Nucleobindin-1 chr19 Not Cancer Driver No 1 hippie 56 352 43 43 0
NUCB2_ENST00000622082 NUCB2 P80303 Nucleobindin-2 chr11 Not Cancer Driver No 1 intact, hippie 49 265 40 40 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 151 126 24 24 41
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 83 386 39 39 0
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 1 hippie 45 128 18 18 0
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 Not Cancer Driver No 1 intact, hippie 226 407 123 123 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PCP2 PCP2 Q8IVA1 Purkinje cell protein 2 homolog chr19 Not Cancer Driver No 3 intact, hippie, biogrid 13 136 13 13 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 intact 290 173 45 45 2
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 hippie 73 19 3 3 0
PHF24 PHF24 Q9UPV7 PHD finger protein 24 chr9 Not Cancer Driver No 1 intact, hippie 104 196 56 56 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1 hippie 1669 38 11 11 30
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 24 9 0 0 0
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 Not Cancer Driver No 1 biogrid 46 76 10 10 0
PLD5 PLD5 Q8N7P1 Inactive phospholipase D5 chr1 Not Cancer Driver No 1 biogrid 152 62 18 18 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 Not Cancer Driver No 1 biogrid 27 24 6 6 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PLEKHH3 PLEKHH3 Q7Z736 Pleckstrin homology domain-containing family H member 3 chr17 Not Cancer Driver No 1 hippie, biogrid 85 356 43 43 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 Not Cancer Driver No 1 hippie 60 125 4 4 0
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 intact, hippie 48 51 9 9 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 Not Cancer Driver No 1 hippie, biogrid 69 152 19 19 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 Not Cancer Driver No 1 hippie 248 325 64 64 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 Not Cancer Driver No 1 hippie, biogrid 26 39 3 3 2
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 Not Cancer Driver No 1 intact, hippie 65 159 17 17 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 81 313 39 39 0
RASA3 RASA3 Q14644 Ras GTPase-activating protein 3 chr13 Not Cancer Driver No 1 hippie 118 101 19 19 0
RDH13 RDH13 Q8NBN7 Retinol dehydrogenase 13 chr19 Not Cancer Driver No 1 hippie, biogrid 42 48 7 7 0
RGS10 RGS10 O43665 Regulator of G-protein signaling 10 chr10 Not Cancer Driver No 1 hippie 24 85 8 8 0
RGS12 RGS12 O14924 Regulator of G-protein signaling 12 chr4 Not Cancer Driver No 4 intact, hippie, biogrid 208 835 129 129 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 Not Cancer Driver No 6 intact, hippie, biogrid 57 309 37 37 0
RGS16 RGS16 O15492 Regulator of G-protein signaling 16 chr1 Not Cancer Driver No 1 hippie 37 28 7 7 0
RGS17 RGS17 Q9UGC6 Regulator of G-protein signaling 17 chr6 Not Cancer Driver No 1 intact, hippie 45 48 11 11 0
RGS18 RGS18 Q9NS28 Regulator of G-protein signaling 18 chr1 Not Cancer Driver No 1 hippie 69 58 25 25 0
RGS19_ENST00000332298 RGS19 P49795 Regulator of G-protein signaling 19 chr20 Not Cancer Driver No 1 hippie 27 71 8 8 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 Not Cancer Driver No 1 hippie 30 50 4 4 0
RGS20 RGS20 O76081 Regulator of G-protein signaling 20 chr8 Not Cancer Driver No 1 hippie 59 194 36 36 0
RGS3 RGS3 P49796 Regulator of G-protein signaling 3 chr9 Not Cancer Driver No 1 hippie 157 619 82 82 0
RGS5_ENST00000313961 RGS5 O15539 Regulator of G-protein signaling 5 chr1 Not Cancer Driver No 1 hippie 45 21 5 5 0
RGS7_ENST00000366563 RGS7 P49802 Regulator of G-protein signaling 7 chr1 Census, Compendium Yes 1 hippie 196 150 50 50 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 93 284 36 36 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RIC8A_ENST00000526104 RIC8A Q9NPQ8 Synembryn-A chr11 Not Cancer Driver No 4 intact, hippie, biogrid 63 163 23 23 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 66 295 39 39 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 Compendium Yes 1 hippie 91 601 87 87 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 hippie, biogrid 38 150 25 25 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 Not Cancer Driver No 1 hippie 86 29 6 6 0
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 Not Cancer Driver No 1 hippie 94 525 56 56 0
SOX30 SOX30 O94993 Transcription factor SOX-30 chr5 Not Cancer Driver No 1 intact, hippie 103 659 89 89 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 Not Cancer Driver No 1 hippie, biogrid 70 241 32 32 0
STT3B STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 1 intact 60 136 9 9 0
STX6 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 33 78 11 11 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 Not Cancer Driver No 1 intact, hippie, biogrid 115 88 9 9 2
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TMEM222_ENST00000374076 TMEM222 Q9H0R3 Transmembrane protein 222 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 19 36 2 2 1
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 102 151 17 17 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TSHR TSHR P16473 Thyrotropin receptor chr14 Census Yes 1 hippie 128 38 9 9 39
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 59 52 11 11 8
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie 67 53 10 10 12
TXNDC5 TXNDC5 Q8NBS9 Thioredoxin domain-containing protein 5 chr6 Not Cancer Driver No 1 hippie 47 104 12 12 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 35 67 13 13 2
UBFD1 UBFD1 O14562 Ubiquitin domain-containing protein UBFD1 chr16 Not Cancer Driver No 1 hippie 30 228 18 18 0
USP33_ENST00000357428 USP33 Q8TEY7 Ubiquitin carboxyl-terminal hydrolase 33 chr1 Not Cancer Driver No 1 hippie, biogrid 138 256 48 48 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie 114 673 80 80 2
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 1 hippie 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0