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GCLM ,GCLM ,P48507
  • Uniprot Accession= P48507
  • Ensembl Transcript= ENST00000370238.7
  • Uniprot Name= GCLM
  • Name= Glutamate--cysteine ligase regulatory subunit
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 17
  • Number of Interaction partner in hippie: 47
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie 18 5 0 0 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 27 62 8 8 0
CPNE3 CPNE3 O75131 Copine-3 chr8 Not Cancer Driver No 1 hippie, biogrid 79 33 5 5 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 Not Cancer Driver No 1 hippie, biogrid 120 52 8 8 3
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 97 312 45 45 0
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 hippie 44 89 14 14 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 Not Cancer Driver No 4 hippie, biogrid 73 167 18 18 3
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie 52 24 4 4 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 Compendium Yes 1 hippie 50 24 0 0 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 36 25 6 6 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 Not Cancer Driver No 1 hippie 43 253 19 19 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 hippie 136 589 92 92 0
NAGK_ENST00000244204 NAGK Q9UJ70 N-acetyl-D-glucosamine kinase chr2 Not Cancer Driver No 1 hippie 46 5 1 1 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OSGIN1 OSGIN1 Q9UJX0 Oxidative stress-induced growth inhibitor 1 chr16 Not Cancer Driver No 1 hippie 57 79 10 10 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 31 33 2 2 0
PARP12 PARP12 Q9H0J9 Protein mono-ADP-ribosyltransferase PARP12 chr7 Not Cancer Driver No 2 hippie, biogrid 78 67 10 10 0
PCBP3 PCBP3 P57721 Poly(rC)-binding protein 3 chr21 Not Cancer Driver No 1 hippie, biogrid 65 230 48 48 0
PHLDA3 PHLDA3 Q9Y5J5 Pleckstrin homology-like domain family A member 3 chr1 Not Cancer Driver No 1 hippie 20 0 0 0 0
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 1 hippie, biogrid 267 142 11 11 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 Not Cancer Driver No 2 hippie, biogrid 49 18 5 5 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 2 hippie, biogrid 94 154 22 22 0
RNF7 RNF7 Q9UBF6 RING-box protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 hippie 74 513 48 48 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 Not Cancer Driver No 1 hippie, biogrid 111 149 27 27 0
SORD SORD Q00796 Sorbitol dehydrogenase chr15 Not Cancer Driver No 1 hippie, biogrid 29 41 7 7 3
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 Not Cancer Driver No 1 hippie 121 659 83 83 2
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 Census, Compendium Yes 1 hippie 33 54 8 8 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRPV5 TRPV5 Q9NQA5 Transient receptor potential cation channel subfamily V member 5 chr7 Not Cancer Driver No 2 hippie, biogrid 206 68 14 14 0
UROS_ENST00000368786 UROS P10746 Uroporphyrinogen-III synthase chr10 Not Cancer Driver No 3 hippie, biogrid 34 7 0 0 21
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WIF1 WIF1 Q9Y5W5 Wnt inhibitory factor 1 chr12 Census Yes 1 hippie, biogrid 74 30 3 3 0