Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
AIM2 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 73 | 78 | 22 | 22 | 0 |
APPL1 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | Not Cancer Driver | No | 1 | hippie | 67 | 292 | 31 | 31 | 1 |
ARID4B | ARID4B | Q4LE39 | AT-rich interactive domain-containing protein 4B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 1005 | 118 | 118 | 0 |
ASF1A | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 69 | 2 | 2 | 0 |
ASXL1_ENST00000613218 | ASXL1 | Q8IXJ9 | Polycomb group protein ASXL1 | chr20 | Census, Compendium | Yes | 1 | hippie | 205 | 1300 | 174 | 174 | 0 |
ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie | 200 | 115 | 29 | 29 | 31 |
BCL11A | BCL11A | Q9H165 | B-cell lymphoma/leukemia 11A | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 210 | 677 | 171 | 171 | 3 |
BCL11B | BCL11B | Q9C0K0 | B-cell lymphoma/leukemia 11B | chr14 | Census, Compendium | Yes | 1 | hippie, biogrid | 156 | 699 | 114 | 114 | 2 |
BPTF_ENST00000321892 | BPTF | Q12830 | Nucleosome-remodeling factor subunit BPTF | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 309 | 2187 | 218 | 218 | 2 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRD1_ENST00000216267 | BRD1 | O95696 | Bromodomain-containing protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 171 | 425 | 68 | 68 | 0 |
BRD2_ENST00000374831 | BRD2 | P25440 | Bromodomain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 108 | 632 | 85 | 85 | 0 |
BRD3 | BRD3 | Q15059 | Bromodomain-containing protein 3 | chr9 | Census | Yes | 1 | hippie | 87 | 566 | 68 | 68 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BRMS1L | BRMS1L | Q5PSV4 | Breast cancer metastasis-suppressor 1-like protein | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 160 | 17 | 17 | 0 |
CALCOCO2_ENST00000258947 | CALCOCO2 | Q13137 | Calcium-binding and coiled-coil domain-containing protein 2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 212 | 19 | 19 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CDC16_ENST00000356221 | CDC16 | Q13042 | Cell division cycle protein 16 homolog | chr13 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 68 | 54 | 7 | 7 | 0 |
CDK2AP1 | CDK2AP1 | O14519 | Cyclin-dependent kinase 2-associated protein 1 | chr12 | Not Cancer Driver | No | 4 | hippie, biogrid | 10 | 76 | 8 | 8 | 0 |
CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | Not Cancer Driver | No | 1 | hippie | 17 | 44 | 3 | 3 | 0 |
CENPA | CENPA | P49450 | Histone H3-like centromeric protein A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 50 | 4 | 4 | 0 |
CEP70_ENST00000484888 | CEP70 | Q8NHQ1 | Centrosomal protein of 70 kDa | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 79 | 223 | 32 | 32 | 0 |
CHAF1A | CHAF1A | Q13111 | Chromatin assembly factor 1 subunit A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 133 | 767 | 99 | 99 | 0 |
CHAF1B | CHAF1B | Q13112 | Chromatin assembly factor 1 subunit B | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 186 | 30 | 30 | 0 |
CHD3_ENST00000330494 | CHD3 | Q12873 | Chromodomain-helicase-DNA-binding protein 3 | chr17 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 235 | 1015 | 122 | 122 | 18 |
CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | Census, Compendium | Yes | 6 | intact, hippie, biogrid | 419 | 974 | 177 | 177 | 6 |
CHD5 | CHD5 | Q8TDI0 | Chromodomain-helicase-DNA-binding protein 5 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 365 | 931 | 183 | 183 | 0 |
CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CPNE5 | CPNE5 | Q9HCH3 | Copine-5 | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 78 | 83 | 8 | 8 | 0 |
CROT_ENST00000331536 | CROT | Q9UKG9 | Peroxisomal carnitine O-octanoyltransferase | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 107 | 32 | 2 | 2 | 0 |
CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 71 | 75 | 8 | 8 | 4 |
CSNK2A2 | CSNK2A2 | P19784 | Casein kinase II subunit alpha' | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 43 | 13 | 1 | 1 | 0 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
DPY30 | DPY30 | Q9C005 | Protein dpy-30 homolog | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 57 | 6 | 6 | 0 |
EDEM1 | EDEM1 | Q92611 | ER degradation-enhancing alpha-mannosidase-like protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 54 | 141 | 5 | 5 | 0 |
EED_ENST00000263360 | EED | O75530 | Polycomb protein EED | chr11 | Census | Yes | 2 | hippie, biogrid | 64 | 79 | 11 | 11 | 6 |
EIF3D | EIF3D | O15371 | Eukaryotic translation initiation factor 3 subunit D | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 200 | 26 | 26 | 0 |
ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | Not Cancer Driver | No | 1 | hippie | 211 | 829 | 117 | 117 | 9 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | Census, Compendium | Yes | 1 | hippie, biogrid | 120 | 284 | 44 | 44 | 11 |
FAM219A | FAM219A | Q8IW50 | Protein FAM219A | chr9 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 19 | 167 | 18 | 18 | 0 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 176 | 181 | 14 | 14 | 3 |
FBXO44_ENST00000251547 | FBXO44 | Q9H4M3 | F-box only protein 44 | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 27 | 3 | 3 | 0 |
FHL2_ENST00000408995 | FHL2 | Q14192 | Four and a half LIM domains protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 0 | 0 | 0 | 0 |
FOXC1_ENST00000645831 | FOXC1 | Q12948 | Forkhead box protein C1 | chr6 | Not Cancer Driver | No | 1 | hippie | 33 | 411 | 24 | 24 | 32 |
FOXG1 | FOXG1 | P55316 | Forkhead box protein G1 | chr14 | Not Cancer Driver | No | 1 | hippie | 132 | 322 | 79 | 79 | 2 |
FOXJ2 | FOXJ2 | Q9P0K8 | Forkhead box protein J2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 81 | 483 | 65 | 65 | 0 |
FOXP1_ENST00000318789 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | Census, Compendium | Yes | 1 | hippie | 109 | 448 | 71 | 71 | 3 |
FOXP2_ENST00000350908 | FOXP2 | O15409 | Forkhead box protein P2 | chr7 | Not Cancer Driver | No | 1 | hippie | 156 | 444 | 100 | 100 | 1 |
FOXQ1 | FOXQ1 | Q9C009 | Forkhead box protein Q1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 245 | 4 | 4 | 0 |
FOXS1 | FOXS1 | O43638 | Forkhead box protein S1 | chr20 | Not Cancer Driver | No | 1 | hippie | 67 | 226 | 41 | 41 | 0 |
GATAD1 | GATAD1 | Q8WUU5 | GATA zinc finger domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 131 | 4 | 4 | 1 |
GATAD2A_ENST00000360315 | GATAD2A | Q86YP4 | Transcriptional repressor p66-alpha | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 88 | 548 | 77 | 77 | 0 |
GOLGA2_ENST00000611957 | GOLGA2 | Q08379 | Golgin subfamily A member 2 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 115 | 854 | 96 | 96 | 0 |
GPSM3_ENST00000375043 | GPSM3 | Q9Y4H4 | G-protein-signaling modulator 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 26 | 160 | 26 | 26 | 0 |
HAT1 | HAT1 | O14929 | Histone acetyltransferase type B catalytic subunit | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 14 | 2 | 2 | 0 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 9 | intact, hippie, biogrid | 47 | 135 | 10 | 10 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | Not Cancer Driver | No | 8 | intact, hippie, biogrid | 46 | 145 | 14 | 14 | 0 |
HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 40 | 352 | 40 | 40 | 0 |
HJURP | HJURP | Q8NCD3 | Holliday junction recognition protein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 572 | 85 | 85 | 0 |
HMG20A | HMG20A | Q9NP66 | High mobility group protein 20A | chr15 | Not Cancer Driver | No | 1 | hippie | 58 | 308 | 44 | 44 | 0 |
HMGXB4 | HMGXB4 | Q9UGU5 | HMG domain-containing protein 4 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 475 | 56 | 56 | 0 |
HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
HSPA2_ENST00000247207 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 93 | 286 | 38 | 38 | 0 |
IKZF1 | IKZF1 | Q13422 | DNA-binding protein Ikaros | chr7 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 143 | 326 | 92 | 92 | 5 |
IKZF3 | IKZF3 | Q9UKT9 | Zinc finger protein Aiolos | chr17 | Census, Compendium | Yes | 1 | hippie, biogrid | 106 | 284 | 60 | 60 | 1 |
KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 266 | 27 | 27 | 0 |
KLF3 | KLF3 | P57682 | Krueppel-like factor 3 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 53 | 243 | 38 | 38 | 0 |
KPNA1 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 65 | 121 | 18 | 18 | 0 |
KPNA5 | KPNA5 | O15131 | Importin subunit alpha-6 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 133 | 13 | 13 | 0 |
L3MBTL2 | L3MBTL2 | Q969R5 | Lethal(3)malignant brain tumor-like protein 2 | chr22 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 95 | 210 | 38 | 38 | 0 |
LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 350 | 44 | 44 | 0 |
LIN37 | LIN37 | Q96GY3 | Protein lin-37 homolog | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 239 | 34 | 34 | 0 |
LIN52 | LIN52 | Q52LA3 | Protein lin-52 homolog | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 42 | 3 | 3 | 0 |
LIN9 | LIN9 | Q5TKA1 | Protein lin-9 homolog | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 219 | 25 | 25 | 0 |
LOX | LOX | P28300 | Protein-lysine 6-oxidase | chr5 | Compendium | Yes | 1 | intact, hippie | 44 | 172 | 11 | 11 | 4 |
LOXL1 | LOXL1 | Q08397 | Lysyl oxidase homolog 1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 49 | 337 | 14 | 14 | 0 |
LOXL3 | LOXL3 | P58215 | Lysyl oxidase homolog 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 91 | 86 | 17 | 17 | 0 |
MAGEA3 | MAGEA3 | P43357 | Melanoma-associated antigen 3 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 103 | 18 | 18 | 0 |
MAGEE1 | MAGEE1 | Q9HCI5 | Melanoma-associated antigen E1 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 218 | 528 | 123 | 123 | 0 |
MBD2 | MBD2 | Q9UBB5 | Methyl-CpG-binding domain protein 2 | chr18 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 26 | 384 | 25 | 25 | 0 |
MBD3 | MBD3 | O95983 | Methyl-CpG-binding domain protein 3 | chr19 | Not Cancer Driver | No | 8 | intact, hippie, biogrid | 50 | 246 | 46 | 46 | 0 |
MBD3L1_ENST00000305625 | MBD3L1 | Q8WWY6 | Methyl-CpG-binding domain protein 3-like 1 | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 41 | 68 | 18 | 18 | 0 |
MBD3L2 | MBD3L2 | Q8NHZ7 | Methyl-CpG-binding domain protein 3-like 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 188 | 7 | 7 | 0 |
MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 287 | 749 | 159 | 159 | 3 |
MTA1 | MTA1 | Q13330 | Metastasis-associated protein MTA1 | chr14 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 92 | 327 | 42 | 42 | 0 |
MTA2 | MTA2 | O94776 | Metastasis-associated protein MTA2 | chr11 | Not Cancer Driver | No | 8 | intact, hippie, biogrid | 78 | 283 | 32 | 32 | 0 |
MTA3 | MTA3 | Q9BTC8 | Metastasis-associated protein MTA3 | chr2 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 48 | 169 | 18 | 18 | 0 |
MTF2 | MTF2 | Q9Y483 | Metal-response element-binding transcription factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 225 | 28 | 28 | 0 |
MTNR1A | MTNR1A | P48039 | Melatonin receptor type 1A | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 0 | 0 | 0 | 0 |
MYBL2 | MYBL2 | P10244 | Myb-related protein B | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 111 | 506 | 85 | 85 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
NCAPH2_ENST00000420993 | NCAPH2 | Q6IBW4 | Condensin-2 complex subunit H2 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 335 | 39 | 39 | 0 |
NDUFA2 | NDUFA2 | O43678 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 0 | 0 | 0 | 0 |
NDUFA7 | NDUFA7 | O95182 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 103 | 13 | 13 | 0 |
NFATC1 | NFATC1 | O95644 | Nuclear factor of activated T-cells, cytoplasmic 1 | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 173 | 713 | 130 | 130 | 0 |
NFATC2 | NFATC2 | Q13469 | Nuclear factor of activated T-cells, cytoplasmic 2 | chr20 | Census, Compendium | Yes | 1 | hippie, biogrid | 194 | 722 | 162 | 162 | 0 |
NFX1 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | Not Cancer Driver | No | 1 | hippie | 121 | 491 | 46 | 46 | 0 |
NGB | NGB | Q9NPG2 | Neuroglobin | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 3 | 0 | 0 | 0 |
NME7 | NME7 | Q9Y5B8 | Nucleoside diphosphate kinase 7 | chr1 | Not Cancer Driver | No | 1 | hippie | 53 | 0 | 0 | 0 | 0 |
NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | Census, Compendium | Yes | 1 | hippie | 363 | 686 | 87 | 87 | 3 |
NOXA1 | NOXA1 | Q86UR1 | NADPH oxidase activator 1 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 27 | 215 | 14 | 14 | 0 |
NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 552 | 76 | 76 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 30 | 0 | 0 | 5 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 119 | 320 | 34 | 34 | 0 |
PHF1 | PHF1 | O43189 | PHD finger protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 277 | 29 | 29 | 0 |
PHF12 | PHF12 | Q96QT6 | PHD finger protein 12 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 619 | 68 | 68 | 0 |
PHF20L1 | PHF20L1 | A8MW92 | PHD finger protein 20-like protein 1 | chr8 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 163 | 645 | 87 | 87 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PRDM16 | PRDM16 | Q9HAZ2 | Histone-lysine N-methyltransferase PRDM16 | chr1 | Census | Yes | 1 | hippie | 254 | 830 | 152 | 152 | 1 |
PRKAB2 | PRKAB2 | O43741 | 5'-AMP-activated protein kinase subunit beta-2 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 31 | 110 | 12 | 12 | 0 |
PRKAR1A_ENST00000536854 | PRKAR1A | P10644 | cAMP-dependent protein kinase type I-alpha regulatory subunit | chr17 | Census, Compendium | Yes | 1 | hippie | 39 | 66 | 11 | 11 | 17 |
PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 20 | 25 | 5 | 5 | 0 |
PWWP2A | PWWP2A | Q96N64 | PWWP domain-containing protein 2A | chr5 | Census | Yes | 1 | hippie, biogrid | 57 | 601 | 46 | 46 | 0 |
PYHIN1 | PYHIN1 | Q6K0P9 | Pyrin and HIN domain-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 174 | 291 | 99 | 99 | 0 |
QPRT | QPRT | Q15274 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | chr16 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 29 | 7 | 1 | 1 | 0 |
RBBP4 | RBBP4 | Q09028 | Histone-binding protein RBBP4 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 53 | 169 | 23 | 23 | 0 |
RBBP7_ENST00000380087 | RBBP7 | Q16576 | Histone-binding protein RBBP7 | chrX | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 67 | 138 | 19 | 19 | 0 |
RBPMS_ENST00000320203 | RBPMS | Q93062 | RNA-binding protein with multiple splicing | chr8 | Not Cancer Driver | No | 1 | hippie | 23 | 87 | 11 | 11 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 203 | 22 | 22 | 0 |
RPGRIP1 | RPGRIP1 | Q96KN7 | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 219 | 680 | 110 | 110 | 6 |
RUNX1_ENST00000344691 | RUNX1 | Q01196 | Runt-related transcription factor 1 | chr21 | Census, Compendium | Yes | 1 | hippie | 81 | 360 | 58 | 58 | 2 |
SALL1 | SALL1 | Q9NSC2 | Sal-like protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 454 | 949 | 334 | 334 | 0 |
SALL4 | SALL4 | Q9UJQ4 | Sal-like protein 4 | chr20 | Census, Compendium | Yes | 1 | hippie, biogrid | 238 | 738 | 188 | 188 | 1 |
SAP130_ENST00000259235 | SAP130 | Q9H0E3 | Histone deacetylase complex subunit SAP130 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 119 | 940 | 107 | 107 | 0 |
SAP30 | SAP30 | O75446 | Histone deacetylase complex subunit SAP30 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 123 | 17 | 17 | 0 |
SBK3 | SBK3 | P0C264 | Uncharacterized serine/threonine-protein kinase SBK3 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 1 | 157 | 0 | 0 | 0 |
SHPRH | SHPRH | Q149N8 | E3 ubiquitin-protein ligase SHPRH | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 227 | 359 | 51 | 51 | 0 |
SIN3A_ENST00000360439 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | Compendium | Yes | 1 | hippie, biogrid | 172 | 617 | 73 | 73 | 0 |
SIN3B | SIN3B | O75182 | Paired amphipathic helix protein Sin3b | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 130 | 316 | 32 | 32 | 0 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 164 | 12 | 12 | 0 |
SLC25A32 | SLC25A32 | Q9H2D1 | Mitochondrial folate transporter/carrier | chr8 | Not Cancer Driver | No | 1 | hippie | 45 | 4 | 0 | 0 | 1 |
SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 1 | intact, hippie | 79 | 137 | 12 | 12 | 0 |
SMARCA1_ENST00000371122 | SMARCA1 | P28370 | Probable global transcription activator SNF2L1 | chrX | Compendium | Yes | 1 | hippie, biogrid | 143 | 309 | 41 | 41 | 0 |
SMARCA5 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 116 | 363 | 48 | 48 | 0 |
SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 62 | 488 | 56 | 56 | 0 |
SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 1 | hippie | 39 | 312 | 39 | 39 | 0 |
SOX6_ENST00000528429 | SOX6 | P35712 | Transcription factor SOX-6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 130 | 744 | 118 | 118 | 0 |
SRF | SRF | P11831 | Serum response factor | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 44 | 443 | 42 | 42 | 0 |
STMN2_ENST00000220876 | STMN2 | Q93045 | Stathmin-2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 122 | 23 | 23 | 0 |
SUDS3 | SUDS3 | Q9H7L9 | Sin3 histone deacetylase corepressor complex component SDS3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 249 | 28 | 28 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
SUZ12 | SUZ12 | Q15022 | Polycomb protein SUZ12 | chr17 | Census, Compendium | Yes | 2 | hippie, biogrid | 83 | 483 | 46 | 46 | 3 |
TCF19_ENST00000376255 | TCF19 | Q9Y242 | Transcription factor 19 | chr6 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 33 | 228 | 24 | 24 | 0 |
TCF20 | TCF20 | Q9UGU0 | Transcription factor 20 | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 234 | 1811 | 214 | 214 | 1 |
TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 310 | 16 | 16 | 0 |
TEX11_ENST00000344304 | TEX11 | Q8IYF3 | Testis-expressed protein 11 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 139 | 30 | 3 | 3 | 2 |
THRSP | THRSP | Q92748 | Thyroid hormone-inducible hepatic protein | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 47 | 7 | 7 | 0 |
TRAF1 | TRAF1 | Q13077 | TNF receptor-associated factor 1 | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 51 | 63 | 9 | 9 | 0 |
TRAF3IP1 | TRAF3IP1 | Q8TDR0 | TRAF3-interacting protein 1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 507 | 60 | 60 | 4 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRIM27 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | Census | Yes | 1 | intact, hippie | 59 | 87 | 11 | 11 | 0 |
TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | Not Cancer Driver | No | 1 | hippie | 119 | 492 | 60 | 60 | 3 |
TRPS1_ENST00000220888 | TRPS1 | Q9UHF7 | Zinc finger transcription factor Trps1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 348 | 800 | 216 | 216 | 7 |
TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 61 | 77 | 14 | 14 | 0 |
UHRF2 | UHRF2 | Q96PU4 | E3 ubiquitin-protein ligase UHRF2 | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 253 | 22 | 22 | 0 |
USHBP1 | USHBP1 | Q8N6Y0 | Usher syndrome type-1C protein-binding protein 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 118 | 583 | 95 | 95 | 0 |
WDR77 | WDR77 | Q9BQA1 | Methylosome protein 50 | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 41 | 2 | 2 | 0 |
ZBED1 | ZBED1 | O96006 | E3 SUMO-protein ligase ZBED1 | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 137 | 97 | 12 | 12 | 0 |
ZBTB1 | ZBTB1 | Q9Y2K1 | Zinc finger and BTB domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 70 | 271 | 27 | 27 | 0 |
ZBTB2 | ZBTB2 | Q8N680 | Zinc finger and BTB domain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 75 | 216 | 30 | 30 | 0 |
ZBTB33 | ZBTB33 | Q86T24 | Transcriptional regulator Kaiso | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 110 | 352 | 58 | 58 | 0 |
ZBTB46_ENST00000302995 | ZBTB46 | Q86UZ6 | Zinc finger and BTB domain-containing protein 46 | chr20 | Not Cancer Driver | No | 3 | hippie, biogrid | 115 | 301 | 68 | 68 | 0 |
ZBTB7A_ENST00000601588 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | Not Cancer Driver | No | 1 | hippie | 60 | 285 | 30 | 30 | 0 |
ZBTB7C_ENST00000590800 | ZBTB7C | A1YPR0 | Zinc finger and BTB domain-containing protein 7C | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 91 | 249 | 40 | 40 | 0 |
ZGPAT | ZGPAT | Q8N5A5 | Zinc finger CCCH-type with G patch domain-containing protein | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 346 | 49 | 49 | 0 |
ZMYND8_ENST00000311275 | ZMYND8 | Q9ULU4 | Protein kinase C-binding protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 176 | 830 | 124 | 124 | 0 |
ZNF219 | ZNF219 | Q9P2Y4 | Zinc finger protein 219 | chr14 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 44 | 628 | 37 | 37 | 0 |
ZNF512B | ZNF512B | Q96KM6 | Zinc finger protein 512B | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 101 | 694 | 83 | 83 | 0 |
ZNF784 | ZNF784 | Q8NCA9 | Zinc finger protein 784 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 215 | 21 | 21 | 0 |
ZNF827 | ZNF827 | Q17R98 | Zinc finger protein 827 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 158 | 754 | 123 | 123 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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