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FOXC1_ENST00000645831 ,FOXC1 ,Q12948
  • Uniprot Accession= Q12948
  • Ensembl Transcript= ENST00000645831.1
  • Uniprot Name= FOXC1
  • Name= Forkhead box protein C1
  • Chromosome= chr6
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 6
  • Number of Interaction partner in biogrid: 20
  • Number of Interaction partner in hippie: 93
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 Not Cancer Driver No 1 hippie, biogrid 73 78 22 22 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 hippie, biogrid 29 195 9 9 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX Census, Compendium Yes 1 hippie 291 1285 226 226 1
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie 14 103 6 6 2
C5orf24_ENST00000435259 C5orf24 Q7Z6I8 UPF0461 protein C5orf24 chr5 Not Cancer Driver No 1 hippie 22 182 22 22 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 Not Cancer Driver No 1 hippie 102 528 62 62 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 hippie 25 277 23 23 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 Not Cancer Driver No 1 hippie 157 641 134 134 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie 44 37 2 2 0
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 Not Cancer Driver No 1 hippie 71 223 57 57 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 Not Cancer Driver No 1 hippie 42 357 30 30 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact 121 195 27 27 2
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 75 20 3 3 7
FEV FEV Q99581 Protein FEV chr2 Census Yes 1 hippie 15 55 0 0 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 1 intact 100 295 53 53 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 Not Cancer Driver No 1 hippie 33 411 24 24 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 Not Cancer Driver No 1 hippie 63 369 33 33 1
FOXD4 FOXD4 Q12950 Forkhead box protein D4 chr9 Not Cancer Driver No 1 hippie 77 327 55 55 0
FOXI1 FOXI1 Q12951 Forkhead box protein I1 chr5 Not Cancer Driver No 1 hippie 91 253 66 66 0
FOXJ2 FOXJ2 Q9P0K8 Forkhead box protein J2 chr12 Not Cancer Driver No 1 hippie 81 483 65 65 0
FOXL1 FOXL1 Q12952 Forkhead box protein L1 chr16 Not Cancer Driver No 1 hippie 62 212 26 26 0
FOXS1 FOXS1 O43638 Forkhead box protein S1 chr20 Not Cancer Driver No 1 hippie 67 226 41 41 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 Census, Compendium Yes 1 hippie 72 370 49 49 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 Census, Compendium Yes 2 intact, hippie 111 364 87 87 2
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 Not Cancer Driver No 1 hippie 76 510 67 67 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 hippie 25 203 20 20 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
HOXB9 HOXB9 P17482 Homeobox protein Hox-B9 chr17 Not Cancer Driver No 1 hippie 28 191 27 27 0
HOXC13 HOXC13 P31276 Homeobox protein Hox-C13 chr12 Census, Compendium Yes 1 hippie 48 203 33 33 0
HOXD13 HOXD13 P35453 Homeobox protein Hox-D13 chr2 Census, Compendium Yes 1 hippie 43 113 12 12 9
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 hippie, biogrid 149 251 52 52 0
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 29 130 7 7 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 hippie 13 204 8 8 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 Compendium Yes 1 hippie 56 177 29 29 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 hippie 75 483 74 74 46
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 Not Cancer Driver No 1 hippie 89 267 62 62 0
METTL6 METTL6 Q8TCB7 tRNA N(3)-methylcytidine methyltransferase METTL6 chr3 Not Cancer Driver No 3 hippie, biogrid 38 20 0 0 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
NAGK_ENST00000244204 NAGK Q9UJ70 N-acetyl-D-glucosamine kinase chr2 Not Cancer Driver No 1 hippie, biogrid 46 5 1 1 0
NDUFA11_ENST00000308961 NDUFA11 Q86Y39 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 chr19 Not Cancer Driver No 1 hippie 6 0 0 0 0
NFIA_ENST00000403491 NFIA Q12857 Nuclear factor 1 A-type chr1 Not Cancer Driver No 1 hippie 78 347 55 55 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 Census Yes 1 hippie 63 254 36 36 3
NFIC NFIC P08651 Nuclear factor 1 C-type chr19 Not Cancer Driver No 1 hippie 61 327 44 44 0
NFIX_ENST00000592199 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 hippie 60 305 40 40 6
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 119 320 34 34 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PAX7_ENST00000420770 PAX7 P23759 Paired box protein Pax-7 chr1 Census Yes 1 hippie 97 401 77 77 1
PAX9 PAX9 P55771 Paired box protein Pax-9 chr14 Not Cancer Driver No 1 hippie 52 198 32 32 1
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 Census Yes 1 hippie 82 290 57 57 0
PBX2 PBX2 P40425 Pre-B-cell leukemia transcription factor 2 chr6 Not Cancer Driver No 1 hippie 57 297 43 43 0
PITX2_ENST00000354925 PITX2 Q99697 Pituitary homeobox 2 chr4 Not Cancer Driver No 1 hippie 74 185 43 43 13
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 Not Cancer Driver No 1 hippie 95 433 50 50 0
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 1 hippie, biogrid 37 12 0 0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 2 hippie, biogrid 179 0 0 0 4
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 hippie 60 68 10 10 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 3 hippie, biogrid 50 65 9 9 0
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 43 71 7 7 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 174 291 99 99 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 Census, Compendium Yes 1 intact 70 167 14 14 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 Not Cancer Driver No 1 intact 82 164 24 24 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RECQL_ENST00000421138 RECQL P46063 ATP-dependent DNA helicase Q1 chr12 Not Cancer Driver No 1 hippie 67 91 5 5 0
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 6 2 2 0
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 Not Cancer Driver No 1 hippie 454 949 334 334 0
SATB1_ENST00000454909 SATB1 Q01826 DNA-binding protein SATB1 chr3 Compendium Yes 1 hippie 130 482 84 84 12
SATB2 SATB2 Q9UPW6 DNA-binding protein SATB2 chr2 Not Cancer Driver No 1 hippie 164 412 100 100 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 Not Cancer Driver No 1 hippie, biogrid 19 318 16 16 4
SLC9A3R2 SLC9A3R2 Q15599 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 chr16 Not Cancer Driver No 1 hippie, biogrid 26 328 26 26 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX Compendium Yes 1 hippie 143 309 41 41 0
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 Not Cancer Driver No 1 hippie 116 363 48 48 0
SOX15_ENST00000538513 SOX15 O60248 Protein SOX-15 chr17 Not Cancer Driver No 1 hippie 18 227 18 18 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 Compendium Yes 1 hippie 81 378 59 59 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 Not Cancer Driver No 1 hippie 182 665 162 162 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 hippie 130 744 118 118 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 Not Cancer Driver No 1 hippie 136 680 101 101 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 hippie 63 332 44 44 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TBXT TBXT O15178 T-box transcription factor T chr6 Not Cancer Driver No 1 hippie 110 253 69 69 1
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 Not Cancer Driver No 1 hippie 52 157 24 24 1
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 310 16 16 0
TFAP2C TFAP2C Q92754 Transcription factor AP-2 gamma chr20 Not Cancer Driver No 1 intact 76 282 41 41 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TLX1 TLX1 P31314 T-cell leukemia homeobox protein 1 chr10 Census Yes 1 hippie 28 223 17 17 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 Census Yes 1 hippie 40 179 24 24 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
UBP1 UBP1 Q9NZI7 Upstream-binding protein 1 chr3 Not Cancer Driver No 1 hippie 58 233 29 29 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0