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FLAD1 ,FLAD1 ,Q8NFF5
  • Uniprot Accession= Q8NFF5
  • Ensembl Transcript= ENST00000292180.7
  • Uniprot Name= FLAD1
  • Name= FAD synthase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 13
  • Number of Interaction partner in biogrid: 44
  • Number of Interaction partner in hippie: 99
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 123 203 25 25 5
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 69 28 5 5 12
ANKRD39 ANKRD39 Q53RE8 Ankyrin repeat domain-containing protein 39 chr2 Not Cancer Driver No 1 hippie, biogrid 19 38 2 2 0
ANXA7 ANXA7 P20073 Annexin A7 chr10 Not Cancer Driver No 1 hippie 68 215 37 37 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 Not Cancer Driver No 1 intact, hippie 36 101 6 6 9
AUH AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 34 29 0 0 1
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie, biogrid 115 546 73 73 10
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 6 6 2
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 1 hippie 61 224 26 26 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CELA2A CELA2A P08217 Chymotrypsin-like elastase family member 2A chr1 Not Cancer Driver No 1 hippie, biogrid 39 4 4 4 2
CLVS2 CLVS2 Q5SYC1 Clavesin-2 chr6 Not Cancer Driver No 1 intact, hippie 123 79 30 30 0
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 Not Cancer Driver No 1 intact, hippie 55 67 10 10 0
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 Not Cancer Driver No 1 intact, hippie 27 23 6 6 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 50 13 2 2 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 intact, hippie 138 270 43 43 22
DUS1L_ENST00000306796 DUS1L Q6P1R4 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like chr17 Not Cancer Driver No 1 hippie, biogrid 52 110 10 10 0
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX Not Cancer Driver No 1 hippie 40 109 12 12 0
EYA4_ENST00000367895 EYA4 O95677 Eyes absent homolog 4 chr6 Not Cancer Driver No 1 hippie 183 337 108 108 2
FAM19A3_ENST00000361886 TAFA3 Q7Z5A8 Chemokine-like protein TAFA-3 chr1 Not Cancer Driver No 1 intact, hippie 17 6 0 0 0
FLAD1 FLAD1 Q8NFF5 FAD synthase chr1 Not Cancer Driver No 2 intact, hippie 81 59 6 6 1
FOXD3 FOXD3 Q9UJU5 Forkhead box protein D3 chr1 Not Cancer Driver No 1 hippie, biogrid 32 261 17 17 0
FSCN3 FSCN3 Q9NQT6 Fascin-3 chr7 Not Cancer Driver No 2 hippie, biogrid 101 5 0 0 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
GEMIN4 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 hippie 101 24 1 1 0
GFM1_ENST00000486715 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 74 79 7 7 4
GOLGA6L2 GOLGA6L2 Q8N9W4 Golgin subfamily A member 6-like protein 2 chr15 Not Cancer Driver No 1 hippie 57 830 50 50 0
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 Not Cancer Driver No 1 hippie 84 134 27 27 0
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 36 25 6 6 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
ISCA1 ISCA1 Q9BUE6 Iron-sulfur cluster assembly 1 homolog, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 8 11 1 1 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 Not Cancer Driver No 1 hippie 189 1278 142 142 2
KLHL14 KLHL14 Q9P2G3 Kelch-like protein 14 chr18 Not Cancer Driver No 3 intact, hippie, biogrid 117 81 10 10 0
L3MBTL3_ENST00000368136 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 Not Cancer Driver No 1 intact, hippie 117 351 59 59 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MCUR1 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 30 65 0 0 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
MDP1 MDP1 Q86V88 Magnesium-dependent phosphatase 1 chr14 Not Cancer Driver No 1 hippie 25 35 8 8 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 Not Cancer Driver No 1 hippie 28 105 13 13 0
MRPS26 MRPS26 Q9BYN8 28S ribosomal protein S26, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 18 102 6 6 0
MRRF MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 23 118 9 9 0
MTIF3_ENST00000381120 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 26 180 19 19 0
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 58 150 8 8 2
NIF3L1_ENST00000409357 NIF3L1 Q9GZT8 NIF3-like protein 1 chr2 Not Cancer Driver No 1 hippie 55 43 3 3 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie 21 37 3 3 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 Not Cancer Driver No 1 hippie, biogrid 36 278 29 29 0
PDE6H PDE6H Q13956 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr12 Not Cancer Driver No 1 hippie, biogrid 15 59 14 14 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 52 50 10 10 0
PFAS PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 Not Cancer Driver No 1 hippie, biogrid 157 380 36 36 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHO2 PLEKHO2 Q8TD55 Pleckstrin homology domain-containing family O member 2 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 61 402 56 56 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PRTFDC1 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 2 intact, hippie 29 3 0 0 0
PSG1_ENST00000436291 PSG1 P11464 Pregnancy-specific beta-1-glycoprotein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 168 78 29 29 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 Not Cancer Driver No 1 hippie, biogrid 44 21 6 6 3
PTP4A1 PTP4A1 Q93096 Protein tyrosine phosphatase type IVA 1 chr6 Not Cancer Driver No 1 hippie 21 2 0 0 0
PTP4A2 PTP4A2 Q12974 Protein tyrosine phosphatase type IVA 2 chr1 Not Cancer Driver No 1 hippie 14 3 1 1 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie 49 140 25 25 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 202 578 75 75 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie 54 143 15 15 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 2 intact, hippie 68 363 43 43 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
SCGB1C1 SCGB1C1 Q8TD33 Secretoglobin family 1C member 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 39 17 2 2 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie, biogrid 41 82 10 10 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 hippie 2 181 2 2 0
SORD SORD Q00796 Sorbitol dehydrogenase chr15 Not Cancer Driver No 1 hippie, biogrid 29 41 7 7 3
SPANXN4 SPANXN4 Q5MJ08 Sperm protein associated with the nucleus on the X chromosome N4 chrX Not Cancer Driver No 1 hippie, biogrid 15 99 15 15 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie, biogrid 62 64 5 5 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 Not Cancer Driver No 1 hippie 26 13 4 4 0
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 Not Cancer Driver No 1 hippie 66 91 14 14 2
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 1 hippie 205 1735 195 195 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 hippie 132 799 63 63 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 74 110 11 11 0
TRIM23 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 Not Cancer Driver No 2 intact, hippie 91 39 2 2 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 37 73 7 7 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 50 3 3 1
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 66 218 29 29 0
UBA52_ENST00000595683 UBA52 P62987 Ubiquitin-60S ribosomal protein L40 chr19 Not Cancer Driver No 1 hippie, biogrid 19 45 8 8 0
UBAP2 UBAP2 Q5T6F2 Ubiquitin-associated protein 2 chr9 Not Cancer Driver No 1 hippie, biogrid 108 1036 98 98 0
VWA8 VWA8 A3KMH1 von Willebrand factor A domain-containing protein 8 chr13 Not Cancer Driver No 1 hippie, biogrid 246 384 36 36 0
ZNF689 ZNF689 Q96CS4 Zinc finger protein 689 chr16 Not Cancer Driver No 1 hippie, biogrid 63 169 15 15 0