Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AARS2 | AARS2 | Q5JTZ9 | Alanine--tRNA ligase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 123 | 203 | 25 | 25 | 5 |
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 28 | 5 | 5 | 12 |
| ANKRD39 | ANKRD39 | Q53RE8 | Ankyrin repeat domain-containing protein 39 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 38 | 2 | 2 | 0 |
| ANXA7 | ANXA7 | P20073 | Annexin A7 | chr10 | Not Cancer Driver | No | 1 | hippie | 68 | 215 | 37 | 37 | 0 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 34 | 103 | 14 | 14 | 0 |
| APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 101 | 6 | 6 | 9 |
| AUH | AUH | Q13825 | Methylglutaconyl-CoA hydratase, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 29 | 0 | 0 | 1 |
| BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
| BICD2_ENST00000375512 | BICD2 | Q8TD16 | Protein bicaudal D homolog 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 546 | 73 | 73 | 10 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 103 | 6 | 6 | 2 |
| CDC25C | CDC25C | P30307 | M-phase inducer phosphatase 3 | chr5 | Not Cancer Driver | No | 1 | hippie | 61 | 224 | 26 | 26 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 1 | hippie | 48 | 121 | 30 | 30 | 0 |
| CELA2A | CELA2A | P08217 | Chymotrypsin-like elastase family member 2A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 4 | 4 | 4 | 2 |
| CLVS2 | CLVS2 | Q5SYC1 | Clavesin-2 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 123 | 79 | 30 | 30 | 0 |
| COPS3 | COPS3 | Q9UNS2 | COP9 signalosome complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 55 | 67 | 10 | 10 | 0 |
| COX8A | COX8A | P10176 | Cytochrome c oxidase subunit 8A, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 1 | 0 | 0 | 0 |
| CRABP2_ENST00000368221 | CRABP2 | P29373 | Cellular retinoic acid-binding protein 2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 27 | 23 | 6 | 6 | 0 |
| CS | CS | O75390 | Citrate synthase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 13 | 2 | 2 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | Census | Yes | 1 | intact, hippie | 138 | 270 | 43 | 43 | 22 |
| DUS1L_ENST00000306796 | DUS1L | Q6P1R4 | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 110 | 10 | 10 | 0 |
| DUSP9 | DUSP9 | Q99956 | Dual specificity protein phosphatase 9 | chrX | Not Cancer Driver | No | 1 | hippie | 40 | 109 | 12 | 12 | 0 |
| EYA4_ENST00000367895 | EYA4 | O95677 | Eyes absent homolog 4 | chr6 | Not Cancer Driver | No | 1 | hippie | 183 | 337 | 108 | 108 | 2 |
| FAM19A3_ENST00000361886 | TAFA3 | Q7Z5A8 | Chemokine-like protein TAFA-3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 6 | 0 | 0 | 0 |
| FLAD1 | FLAD1 | Q8NFF5 | FAD synthase | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 81 | 59 | 6 | 6 | 1 |
| FOXD3 | FOXD3 | Q9UJU5 | Forkhead box protein D3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 261 | 17 | 17 | 0 |
| FSCN3 | FSCN3 | Q9NQT6 | Fascin-3 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 101 | 5 | 0 | 0 | 0 |
| FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 88 | 312 | 53 | 53 | 0 |
| GEMIN4 | GEMIN4 | P57678 | Gem-associated protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 24 | 1 | 1 | 0 |
| GFM1_ENST00000486715 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 79 | 7 | 7 | 4 |
| GOLGA6L2 | GOLGA6L2 | Q8N9W4 | Golgin subfamily A member 6-like protein 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 57 | 830 | 50 | 50 | 0 |
| GRB7_ENST00000394209 | GRB7 | Q14451 | Growth factor receptor-bound protein 7 | chr17 | Not Cancer Driver | No | 1 | hippie | 84 | 134 | 27 | 27 | 0 |
| HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 29 | 2 | 2 | 0 |
| HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | hippie | 36 | 25 | 6 | 6 | 0 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 61 | 82 | 6 | 6 | 2 |
| IMMP1L | IMMP1L | Q96LU5 | Mitochondrial inner membrane protease subunit 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 3 | 0 | 0 | 0 |
| IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 7 | 7 | 0 |
| ISCA1 | ISCA1 | Q9BUE6 | Iron-sulfur cluster assembly 1 homolog, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 11 | 1 | 1 | 0 |
| KDM6B_ENST00000448097 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | Not Cancer Driver | No | 1 | hippie | 189 | 1278 | 142 | 142 | 2 |
| KLHL14 | KLHL14 | Q9P2G3 | Kelch-like protein 14 | chr18 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 117 | 81 | 10 | 10 | 0 |
| L3MBTL3_ENST00000368136 | L3MBTL3 | Q96JM7 | Lethal(3)malignant brain tumor-like protein 3 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 117 | 351 | 59 | 59 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 519 | 90 | 17 | 17 | 23 |
| MCUR1 | MCUR1 | Q96AQ8 | Mitochondrial calcium uniporter regulator 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 65 | 0 | 0 | 0 |
| MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 8 | 1 | 1 | 3 |
| MDP1 | MDP1 | Q86V88 | Magnesium-dependent phosphatase 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 25 | 35 | 8 | 8 | 0 |
| METTL17_ENST00000339374 | METTL17 | Q9H7H0 | Methyltransferase-like protein 17, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 95 | 16 | 16 | 0 |
| MGST3 | MGST3 | O14880 | Microsomal glutathione S-transferase 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 0 | 0 | 0 | 0 |
| MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
| MRPL58 | MRPL58 | Q14197 | Peptidyl-tRNA hydrolase ICT1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 28 | 105 | 13 | 13 | 0 |
| MRPS26 | MRPS26 | Q9BYN8 | 28S ribosomal protein S26, mitochondrial | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 102 | 6 | 6 | 0 |
| MRRF | MRRF | Q96E11 | Ribosome-recycling factor, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 118 | 9 | 9 | 0 |
| MTIF3_ENST00000381120 | MTIF3 | Q9H2K0 | Translation initiation factor IF-3, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 180 | 19 | 19 | 0 |
| MTMR14 | MTMR14 | Q8NCE2 | Myotubularin-related protein 14 | chr3 | Not Cancer Driver | No | 1 | hippie | 58 | 150 | 8 | 8 | 2 |
| NIF3L1_ENST00000409357 | NIF3L1 | Q9GZT8 | NIF3-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 55 | 43 | 3 | 3 | 0 |
| NUDT21 | NUDT21 | O43809 | Cleavage and polyadenylation specificity factor subunit 5 | chr16 | Not Cancer Driver | No | 1 | hippie | 21 | 37 | 3 | 3 | 0 |
| NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
| OTP | OTP | Q5XKR4 | Homeobox protein orthopedia | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 278 | 29 | 29 | 0 |
| PDE6H | PDE6H | Q13956 | Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 59 | 14 | 14 | 0 |
| PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
| PDK1_ENST00000282077 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 52 | 50 | 10 | 10 | 0 |
| PFAS | PFAS | O15067 | Phosphoribosylformylglycinamidine synthase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 380 | 36 | 36 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLEKHO2 | PLEKHO2 | Q8TD55 | Pleckstrin homology domain-containing family O member 2 | chr15 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 61 | 402 | 56 | 56 | 0 |
| PMPCA | PMPCA | Q10713 | Mitochondrial-processing peptidase subunit alpha | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 23 | 3 | 3 | 4 |
| PRTFDC1 | PRTFDC1 | Q9NRG1 | Phosphoribosyltransferase domain-containing protein 1 | chr10 | Not Cancer Driver | No | 2 | intact, hippie | 29 | 3 | 0 | 0 | 0 |
| PSG1_ENST00000436291 | PSG1 | P11464 | Pregnancy-specific beta-1-glycoprotein 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 168 | 78 | 29 | 29 | 0 |
| PSPH_ENST00000275605 | PSPH | P78330 | Phosphoserine phosphatase | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 21 | 6 | 6 | 3 |
| PTP4A1 | PTP4A1 | Q93096 | Protein tyrosine phosphatase type IVA 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 21 | 2 | 0 | 0 | 0 |
| PTP4A2 | PTP4A2 | Q12974 | Protein tyrosine phosphatase type IVA 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 14 | 3 | 1 | 1 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 140 | 25 | 25 | 0 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
| RCC1_ENST00000373833 | RCC1 | P18754 | Regulator of chromosome condensation | chr1 | Not Cancer Driver | No | 1 | hippie | 54 | 143 | 15 | 15 | 0 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
| REL | REL | Q04864 | Proto-oncogene c-Rel | chr2 | Census | Yes | 2 | intact, hippie | 68 | 363 | 43 | 43 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| SCGB1C1 | SCGB1C1 | Q8TD33 | Secretoglobin family 1C member 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| SDCBP_ENST00000260130 | SDCBP | O00560 | Syntenin-1 | chr8 | Not Cancer Driver | No | 1 | hippie | 39 | 17 | 2 | 2 | 0 |
| SH3GLB1_ENST00000370558 | SH3GLB1 | Q9Y371 | Endophilin-B1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 82 | 10 | 10 | 0 |
| SIRT4 | SIRT4 | Q9Y6E7 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 4 | 0 | 0 | 0 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | Census, Compendium | Yes | 1 | hippie | 198 | 195 | 17 | 17 | 8 |
| SMN1_ENST00000503079 | SMN1 | Q16637-2 | Isoform SMN-delta5 of Survival motor neuron protein | chr5 | Not Cancer Driver | No | 1 | hippie | 2 | 181 | 2 | 2 | 0 |
| SORD | SORD | Q00796 | Sorbitol dehydrogenase | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 41 | 7 | 7 | 3 |
| SPANXN4 | SPANXN4 | Q5MJ08 | Sperm protein associated with the nucleus on the X chromosome N4 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 99 | 15 | 15 | 0 |
| ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 64 | 5 | 5 | 0 |
| TBRG4_ENST00000494076 | TBRG4 | Q969Z0 | FAST kinase domain-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 60 | 2 | 2 | 0 |
| TCF4_ENST00000564999 | TCF4 | P15884 | Transcription factor 4 | chr18 | Compendium | Yes | 1 | hippie | 141 | 662 | 136 | 136 | 13 |
| TK1 | TK1 | P04183 | Thymidine kinase, cytosolic | chr17 | Not Cancer Driver | No | 1 | hippie | 26 | 13 | 4 | 4 | 0 |
| TKFC | TKFC | Q3LXA3 | Triokinase/FMN cyclase | chr11 | Not Cancer Driver | No | 1 | hippie | 66 | 91 | 14 | 14 | 2 |
| TNRC6B | TNRC6B | Q9UPQ9 | Trinucleotide repeat-containing gene 6B protein | chr22 | Not Cancer Driver | No | 1 | hippie | 205 | 1735 | 195 | 195 | 0 |
| TNS2_ENST00000314250 | TNS2 | Q63HR2 | Tensin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 132 | 799 | 63 | 63 | 0 |
| TRAP1 | TRAP1 | Q12931 | Heat shock protein 75 kDa, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 110 | 11 | 11 | 0 |
| TRIM23 | TRIM23 | P36406 | E3 ubiquitin-protein ligase TRIM23 | chr5 | Not Cancer Driver | No | 2 | intact, hippie | 91 | 39 | 2 | 2 | 0 |
| TRUB2 | TRUB2 | O95900 | Pseudouridylate synthase TRUB2, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 73 | 7 | 7 | 0 |
| TSFM_ENST00000454289 | TSFM | P43897 | Elongation factor Ts, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 74 | 7 | 7 | 2 |
| TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 50 | 3 | 3 | 1 |
| TULP3_ENST00000448120 | TULP3 | O75386 | Tubby-related protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 66 | 218 | 29 | 29 | 0 |
| UBA52_ENST00000595683 | UBA52 | P62987 | Ubiquitin-60S ribosomal protein L40 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 45 | 8 | 8 | 0 |
| UBAP2 | UBAP2 | Q5T6F2 | Ubiquitin-associated protein 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 1036 | 98 | 98 | 0 |
| VWA8 | VWA8 | A3KMH1 | von Willebrand factor A domain-containing protein 8 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 246 | 384 | 36 | 36 | 0 |
| ZNF689 | ZNF689 | Q96CS4 | Zinc finger protein 689 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 169 | 15 | 15 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|