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FHL3 ,FHL3 ,Q13643
  • Uniprot Accession= Q13643
  • Ensembl Transcript= ENST00000373016.3
  • Uniprot Name= FHL3
  • Name= Four and a half LIM domains protein 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 124
  • Number of Interaction partner in biogrid: 53
  • Number of Interaction partner in hippie: 258
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A1CF_ENST00000373993 A1CF Q9NQ94 APOBEC1 complementation factor chr10 Census Yes 1 intact, hippie 150 63 20 20 0
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact 108 912 75 75 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 Not Cancer Driver No 1 intact, hippie 104 213 29 29 0
ADAMTSL4_ENST00000369038 ADAMTSL4 Q6UY14 ADAMTS-like protein 4 chr1 Not Cancer Driver No 1 hippie 156 563 78 78 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 Not Cancer Driver No 1 hippie, biogrid 130 615 66 66 0
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 Not Cancer Driver No 1 intact 16 77 7 7 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 46 61 8 8 0
AMBP AMBP P02760 Protein AMBP chr9 Not Cancer Driver No 1 intact, hippie 57 61 15 15 0
AMH AMH P03971 Muellerian-inhibiting factor chr19 Not Cancer Driver No 1 hippie, biogrid 19 207 4 4 9
AMOTL1 AMOTL1 Q8IY63 Angiomotin-like protein 1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 136 851 121 121 0
ANKHD1 ANKHD1 Q8IWZ3 Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1 intact 293 1703 193 193 0
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 Q8IWZ3-6 Isoform 6 of Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1 hippie 297 1801 201 201 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 Census, Compendium Yes 1 hippie 175 586 78 78 1
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 Not Cancer Driver No 1 hippie 64 373 42 42 0
ASCL4 ASCL4 Q6XD76 Achaete-scute homolog 4 chr12 Not Cancer Driver No 1 intact, hippie 25 78 15 15 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 Not Cancer Driver No 1 hippie, biogrid 88 468 59 59 2
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 Not Cancer Driver No 1 hippie 63 327 55 55 0
ATXN2_ENST00000550104 ATXN2 Q99700 Ataxin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 146 1228 134 134 0
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 1 hippie 18 104 8 8 0
BAAT_ENST00000395051 BAAT Q14032 Bile acid-CoA:amino acid N-acyltransferase chr9 Not Cancer Driver No 1 intact 88 10 4 4 1
BARX2 BARX2 Q9UMQ3 Homeobox protein BarH-like 2 chr11 Not Cancer Driver No 1 intact, hippie 54 162 40 40 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 Census Yes 3 intact, hippie, biogrid 174 397 59 59 6
C1orf94 C1orf94 Q6P1W5 Uncharacterized protein C1orf94 chr1 Not Cancer Driver No 1 intact, hippie 136 387 102 102 0
C9orf116_ENST00000371789 C9orf116 Q5BN46-2 Isoform 2 of Piercer of microtubule wall 1 protein chr9 Not Cancer Driver No 1 hippie 12 46 2 2 0
CAMKK1_ENST00000348335 CAMKK1 Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 82 246 32 32 0
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 Not Cancer Driver No 1 intact, hippie 204 496 137 137 0
CBX8 CBX8 Q9HC52 Chromobox protein homolog 8 chr17 Not Cancer Driver No 1 hippie 59 309 51 51 0
CCAR1 CCAR1 Q8IX12 Cell division cycle and apoptosis regulator protein 1 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 145 771 76 76 0
CCDC198_ENST00000216445 CCDC198 Q9NVL8 Uncharacterized protein CCDC198 chr14 Not Cancer Driver No 2 intact, hippie 46 255 40 40 0
CCDC36_ENST00000452691 IHO1 Q8IYA8 Interactor of HORMAD1 protein 1 chr3 Not Cancer Driver No 1 intact 83 355 43 43 0
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 Census, Compendium Yes 1 hippie 29 46 8 8 0
CDC25B CDC25B P30305 M-phase inducer phosphatase 2 chr20 Not Cancer Driver No 1 hippie 80 328 43 43 0
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 1 hippie 61 224 26 26 0
CDC42EP1 CDC42EP1 Q00587 Cdc42 effector protein 1 chr22 Not Cancer Driver No 1 hippie 52 371 47 47 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 Not Cancer Driver No 1 hippie 17 44 3 3 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 hippie 335 157 130 130 13
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 Not Cancer Driver No 1 intact, hippie 124 224 38 38 8
CNNM3 CNNM3 Q8NE01 Metal transporter CNNM3 chr2 Not Cancer Driver No 2 intact, hippie 47 101 7 7 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 1 hippie 31 21 1 1 0
COBL_ENST00000265136 COBL O75128 Protein cordon-bleu chr7 Not Cancer Driver No 3 intact, hippie, biogrid 233 1149 216 216 0
CORO1A CORO1A P31146 Coronin-1A chr16 Not Cancer Driver No 1 hippie 51 126 15 15 1
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 hippie 25 277 23 23 0
CREB5 CREB5 Q02930 Cyclic AMP-responsive element-binding protein 5 chr7 Not Cancer Driver No 1 hippie 92 494 89 89 0
CRIP3_ENST00000274990 CRIP3 Q6Q6R5 Cysteine-rich protein 3 chr6 Not Cancer Driver No 1 intact, hippie 31 35 2 2 0
CRYBA2 CRYBA2 P53672 Beta-crystallin A2 chr2 Not Cancer Driver No 1 hippie 22 23 2 2 1
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 Not Cancer Driver No 1 intact, hippie 69 339 46 46 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 2 intact, hippie 48 94 4 4 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie, biogrid 138 207 38 38 2
CYSRT1 CYSRT1 B8A4K4 Cysteine-rich tail protein 1 chr9 Not Cancer Driver No 1 intact, hippie 9 142 5 5 0
DCDC2B DCDC2B A2VCK2 Doublecortin domain-containing protein 2B chr1 Not Cancer Driver No 2 intact, hippie 31 142 11 11 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DLGAP4_ENST00000339266 DLGAP4 Q9Y2H0 Disks large-associated protein 4 chr20 Not Cancer Driver No 1 intact, hippie 170 883 157 157 0
DMRT3 DMRT3 Q9NQL9 Doublesex- and mab-3-related transcription factor 3 chr9 Not Cancer Driver No 1 intact, hippie 94 345 71 71 0
DPPA4 DPPA4 Q7L190 Developmental pluripotency-associated protein 4 chr3 Not Cancer Driver No 1 hippie 94 180 46 46 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 Not Cancer Driver No 1 hippie 81 135 24 24 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 Not Cancer Driver No 1 intact, hippie 132 582 85 85 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EFCAB12_ENST00000326085 EFCAB12 Q6NXP0 EF-hand calcium-binding domain-containing protein 12 chr3 Not Cancer Driver No 1 intact, hippie 94 216 43 43 0
EIF4EBP2 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 Not Cancer Driver No 1 hippie 17 118 14 14 0
EPHA10 EPHA10 Q5JZY3 Ephrin type-A receptor 10 chr1 Not Cancer Driver No 1 intact, hippie 171 225 41 41 0
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 Not Cancer Driver No 1 intact, hippie 61 22 1 1 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie 298 396 70 70 3
EXOSC1 EXOSC1 Q9Y3B2 Exosome complex component CSL4 chr10 Not Cancer Driver No 1 hippie 14 14 2 2 1
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 Not Cancer Driver No 1 hippie 43 31 3 3 0
EYA4_ENST00000367895 EYA4 O95677 Eyes absent homolog 4 chr6 Not Cancer Driver No 1 hippie 183 337 108 108 2
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FADS6_ENST00000614223 FADS6 Q8N9I5 Fatty acid desaturase 6 chr17 Not Cancer Driver No 1 intact, hippie 36 27 2 2 0
FAM110A_ENST00000246100 FAM110A Q9BQ89 Protein FAM110A chr20 Not Cancer Driver No 1 intact, hippie 20 244 12 12 0
FAM126A FAM126A Q9BYI3 Hyccin chr7 Not Cancer Driver No 1 intact, hippie 42 223 18 18 2
FAM222B FAM222B Q8WU58 Protein FAM222B chr17 Not Cancer Driver No 1 intact, hippie 54 476 45 45 0
FAM71C GARIN6 Q8NEG0 Golgi associated RAB2 interactor protein 6 chr12 Not Cancer Driver No 1 intact 56 13 4 4 0
FAM90A1 FAM90A1 Q86YD7 Protein FAM90A1 chr12 Not Cancer Driver No 3 intact, hippie 123 461 121 121 0
FAM98C FAM98C Q17RN3 Protein FAM98C chr19 Not Cancer Driver No 1 hippie, biogrid 48 93 19 19 0
FBXL18_ENST00000453700 FBXL18 Q96ME1-3 Isoform 3 of F-box/LRR-repeat protein 18 chr7 Not Cancer Driver No 1 intact, hippie 46 19 1 1 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 2 intact, hippie, biogrid 173 241 26 26 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
FHL3 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 hippie 33 0 0 0 0
FHL5 FHL5 Q5TD97 Four and a half LIM domains protein 5 chr6 Not Cancer Driver No 1 hippie 106 0 0 0 0
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie 546 1442 288 288 7
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 45 245 33 33 0
FOSL2 FOSL2 P15408 Fos-related antigen 2 chr2 Not Cancer Driver No 2 intact, hippie 54 323 54 54 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 Not Cancer Driver No 1 hippie, biogrid 97 511 65 65 0
FOXN4 FOXN4 Q96NZ1 Forkhead box protein N4 chr12 Not Cancer Driver No 1 intact, hippie 60 377 34 34 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX Census, Compendium Yes 1 hippie 68 242 41 41 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 Census, Compendium Yes 1 hippie 72 370 49 49 6
GBX2 GBX2 P52951 Homeobox protein GBX-2 chr2 Not Cancer Driver No 1 hippie, biogrid 43 243 31 31 0
GCM2 GCM2 O75603 Chorion-specific transcription factor GCMb chr6 Not Cancer Driver No 5 intact, hippie 91 272 50 50 7
GUCD1_ENST00000407471 GUCD1 Q96NT3 Protein GUCD1 chr22 Not Cancer Driver No 1 intact, hippie 26 11 0 0 0
HAPLN2 HAPLN2 Q9GZV7 Hyaluronan and proteoglycan link protein 2 chr1 Not Cancer Driver No 1 intact, hippie 27 35 1 1 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX Not Cancer Driver No 1 intact, hippie 280 1345 181 181 1
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 Not Cancer Driver No 4 intact, hippie, biogrid 158 565 89 89 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 154 686 96 96 0
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 intact, hippie 52 23 3 3 1
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 Not Cancer Driver No 1 hippie 52 8 1 1 0
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 106 284 60 60 1
ITGA7_ENST00000555728 ITGA7 Q13683 Integrin alpha-7 chr12 Not Cancer Driver No 1 hippie 205 283 48 48 0
ITGB5 ITGB5 P18084 Integrin beta-5 chr3 Not Cancer Driver No 1 intact, hippie 86 27 3 3 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 107 531 71 71 3
KCTD3 KCTD3 Q9Y597 BTB/POZ domain-containing protein KCTD3 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 113 324 45 45 0
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 Not Cancer Driver No 1 hippie, biogrid 131 387 48 48 0
KIAA1671_ENST00000406486 KIAA1671 Q9BY89 Uncharacterized protein KIAA1671 chr22 Not Cancer Driver No 1 hippie, biogrid 14 1759 14 14 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 intact, hippie 245 683 113 113 0
KIRREL2 KIRREL2 Q6UWL6 Kin of IRRE-like protein 2 chr19 Not Cancer Driver No 2 intact, hippie 139 303 68 68 0
KLF12 KLF12 Q9Y4X4 Krueppel-like factor 12 chr13 Not Cancer Driver No 1 hippie 60 338 50 50 0
KLF3 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 5 intact, hippie 53 243 38 38 0
KLF8 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 hippie 71 270 53 53 0
KPRP KPRP Q5T749 Keratinocyte proline-rich protein chr1 Not Cancer Driver No 1 intact, hippie 198 193 68 68 0
KRTAP12-1 KRTAP12-1 P59990 Keratin-associated protein 12-1 chr21 Not Cancer Driver No 2 intact, hippie 23 0 0 0 0
KRTAP12-2 KRTAP12-2 P59991 Keratin-associated protein 12-2 chr21 Not Cancer Driver No 2 intact, hippie 28 0 0 0 0
KTI12 KTI12 Q96EK9 Protein KTI12 homolog chr1 Not Cancer Driver No 1 hippie 37 176 18 18 0
LARP4B LARP4B Q92615 La-related protein 4B chr10 Census Yes 3 hippie, biogrid 127 521 91 91 0
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 29 198 24 24 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 intact, hippie 178 687 116 116 0
LHB LHB P01229 Lutropin subunit beta chr19 Not Cancer Driver No 1 intact, hippie 20 0 0 0 1
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 1 intact, hippie 35 14 1 1 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 2 intact, hippie 117 261 40 40 0
LNX2 LNX2 Q8N448 Ligand of Numb protein X 2 chr13 Not Cancer Driver No 1 intact, hippie 85 277 35 35 0
MAP7D2_ENST00000379651 MAP7D2 Q96T17 MAP7 domain-containing protein 2 chrX Not Cancer Driver No 3 intact, hippie, biogrid 124 723 120 120 0
MAP7_ENST00000354570 MAP7 Q14244 Ensconsin chr6 Not Cancer Driver No 1 hippie, biogrid 122 745 122 122 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MED15 MED15 Q96RN5 Mediator of RNA polymerase II transcription subunit 15 chr22 Not Cancer Driver No 1 intact, hippie 95 558 72 72 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 Not Cancer Driver No 1 hippie 64 118 11 11 1
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 1 hippie 43 163 17 17 0
MPZL1 MPZL1 O95297 Myelin protein zero-like protein 1 chr1 Not Cancer Driver No 1 hippie 36 56 7 7 0
MRM3 MRM3 Q9HC36 rRNA methyltransferase 3, mitochondrial chr17 Not Cancer Driver No 2 intact, hippie 45 83 8 8 0
MRPL27 MRPL27 Q9P0M9 39S ribosomal protein L27, mitochondrial chr17 Not Cancer Driver No 1 hippie 16 35 2 2 0
MRRF MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 1 intact, hippie 23 118 9 9 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 Not Cancer Driver No 2 intact, hippie 124 1041 116 116 0
MSRB3 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 Not Cancer Driver No 1 hippie 49 42 14 14 1
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 Not Cancer Driver No 1 hippie 92 327 42 42 0
MTUS1 MTUS1 Q9ULD2 Microtubule-associated tumor suppressor 1 chr8 Not Cancer Driver No 3 hippie, biogrid 127 978 106 106 4
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 hippie 370 1208 329 329 0
MYBPC1_ENST00000550270 MYBPC1 Q00872 Myosin-binding protein C, slow-type chr12 Not Cancer Driver No 1 hippie 227 220 38 38 7
MYBPHL MYBPHL A2RUH7 Myosin-binding protein H-like chr1 Not Cancer Driver No 1 intact, hippie 36 84 6 6 0
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 Not Cancer Driver No 1 intact, hippie 608 1398 189 189 0
MYOZ3_ENST00000517768 MYOZ3 Q8TDC0 Myozenin-3 chr5 Not Cancer Driver No 1 hippie 40 211 27 27 0
MYPOP MYPOP Q86VE0 Myb-related transcription factor, partner of profilin chr19 Not Cancer Driver No 1 intact, hippie 30 361 25 25 0
MZF1 MZF1 P28698 Myeloid zinc finger 1 chr19 Not Cancer Driver No 1 hippie 77 468 49 49 0
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 23 0 0 0 0
NEBL NEBL O76041 Nebulette chr10 Not Cancer Driver No 1 hippie, biogrid 239 773 183 183 0
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 Not Cancer Driver No 1 hippie 42 223 29 29 0
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 Not Cancer Driver No 1 hippie 45 158 22 22 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 75 38 4 4 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 1208 2623 368 368 0
ODF3B ODF3B A8MYP8 Outer dense fiber protein 3B chr22 Not Cancer Driver No 1 intact, hippie 10 183 5 5 0
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 Not Cancer Driver No 1 hippie 66 82 12 12 2
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 Not Cancer Driver No 2 intact, hippie 226 407 123 123 0
PATL1 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 intact, hippie 79 499 49 49 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 intact 290 173 45 45 2
PHC2 PHC2 Q8IXK0 Polyhomeotic-like protein 2 chr1 Not Cancer Driver No 1 hippie 101 674 67 67 0
PHF21A PHF21A Q96BD5 PHD finger protein 21A chr11 Not Cancer Driver No 1 hippie 83 546 68 68 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 1 hippie 80 241 43 43 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 176 434 98 98 8
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 2 hippie, biogrid 144 869 114 114 0
PLEKHF2 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 32 36 4 4 0
PLEKHG4B PLEKHG4B Q96PX9 Pleckstrin homology domain-containing family G member 4B chr5 Not Cancer Driver No 1 intact, hippie 234 704 107 107 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 2 hippie, biogrid 112 312 34 34 0
POM121C_ENST00000607367 POM121C A8CG34 Nuclear envelope pore membrane protein POM 121C chr7 Not Cancer Driver No 1 hippie, biogrid 99 1117 91 91 0
POM121_ENST00000434423 POM121 Q96HA1 Nuclear envelope pore membrane protein POM 121 chr7 Not Cancer Driver No 1 hippie, biogrid 160 1072 130 130 0
PPIG_ENST00000448752 PPIG Q13427 Peptidyl-prolyl cis-trans isomerase G chr2 Not Cancer Driver No 1 intact, hippie 116 644 96 96 0
PPP1R32 PPP1R32 Q7Z5V6 Protein phosphatase 1 regulatory subunit 32 chr11 Not Cancer Driver No 1 intact, hippie 70 379 55 55 0
PRDM7_ENST00000449207 PRDM7 Q9NQW5 Histone-lysine N-methyltransferase PRDM7 chr16 Not Cancer Driver No 1 hippie, biogrid 62 280 26 26 0
PRR35 PRR35 P0CG20 Proline-rich protein 35 chr16 Not Cancer Driver No 1 intact, hippie 55 487 46 46 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 Not Cancer Driver No 1 hippie 57 108 12 12 0
PTP4A2 PTP4A2 Q12974 Protein tyrosine phosphatase type IVA 2 chr1 Not Cancer Driver No 1 hippie 14 3 1 1 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 Census, Compendium Yes 1 intact, hippie 73 192 25 25 0
QKI QKI Q96PU8 Protein quaking chr6 Census, Compendium Yes 1 hippie 52 174 27 27 0
QRICH1_ENST00000357496 QRICH1 Q2TAL8 Transcriptional regulator QRICH1 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 93 423 55 55 0
QSER1 QSER1 Q2KHR3 Glutamine and serine-rich protein 1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 178 1404 145 145 0
RAB40B RAB40B Q12829 Ras-related protein Rab-40B chr17 Not Cancer Driver No 1 hippie 32 39 5 5 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 3 intact, hippie 115 421 74 74 3
RASL12 RASL12 Q9NYN1 Ras-like protein family member 12 chr15 Not Cancer Driver No 1 hippie 37 49 8 8 0
RBM42 RBM42 Q9BTD8 RNA-binding protein 42 chr19 Not Cancer Driver No 1 hippie 78 338 48 48 0
RBMS1 RBMS1 P29558 RNA-binding motif, single-stranded-interacting protein 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 55 243 36 36 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie, biogrid 138 608 71 71 1
RFX3_ENST00000617270 RFX3 P48380 Transcription factor RFX3 chr9 Not Cancer Driver No 1 hippie 113 308 41 41 0
RFX6 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 Not Cancer Driver No 1 intact, hippie 239 422 94 94 3
RHEBL1 RHEBL1 Q8TAI7 GTPase RhebL1 chr12 Not Cancer Driver No 1 hippie 15 5 0 0 0
RNF146 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 Not Cancer Driver No 1 hippie 37 206 24 24 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 54 97 15 15 0
RSPH14 RSPH14 Q9UHP6 Radial spoke head 14 homolog chr22 Not Cancer Driver No 1 intact, hippie 56 15 1 1 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SAP30BP SAP30BP Q9UHR5 SAP30-binding protein chr17 Not Cancer Driver No 1 hippie 25 233 19 19 0
SAXO1 SAXO1 Q8IYX7 Stabilizer of axonemal microtubules 1 chr9 Not Cancer Driver No 3 intact, hippie 63 249 35 35 0
SBF2 SBF2 Q86WG5 Myotubularin-related protein 13 chr11 Not Cancer Driver No 1 hippie 221 367 55 55 0
SCO1 SCO1 O75880 Protein SCO1 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 35 79 7 7 1
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 39 17 2 2 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 120 612 59 59 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 Not Cancer Driver No 1 hippie 223 1327 188 188 5
SH3GLB2_ENST00000372559 SH3GLB2 Q9NR46 Endophilin-B2 chr9 Not Cancer Driver No 1 hippie 39 101 4 4 0
SHE SHE Q5VZ18 SH2 domain-containing adapter protein E chr1 Not Cancer Driver No 1 intact, hippie 65 405 52 52 0
SHKBP1 SHKBP1 Q8TBC3 SH3KBP1-binding protein 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 93 281 32 32 0
SLAIN1_ENST00000466548 SLAIN1 Q8ND83 SLAIN motif-containing protein 1 chr13 Not Cancer Driver No 2 intact, hippie 62 485 58 58 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 2 intact, hippie 37 96 2 2 4
SLC44A3 SLC44A3 Q8N4M1 Choline transporter-like protein 3 chr1 Not Cancer Driver No 1 intact, hippie 76 13 4 4 0
SLIRP SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 Not Cancer Driver No 2 intact, hippie, biogrid 7 41 3 3 0
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 intact, hippie 75 436 63 63 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SNRPB SNRPB P14678 Small nuclear ribonucleoprotein-associated proteins B and B' chr20 Not Cancer Driver No 1 intact, hippie 39 182 34 34 4
SNRPC SNRPC P09234 U1 small nuclear ribonucleoprotein C chr6 Not Cancer Driver No 1 intact, hippie 26 143 26 26 0
SNRPG_ENST00000272348 SNRPG P62308 Small nuclear ribonucleoprotein G chr2 Not Cancer Driver No 2 intact, hippie 8 9 3 3 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 62 488 56 56 0
SPATA8 SPATA8 Q6RVD6 Spermatogenesis-associated protein 8 chr15 Not Cancer Driver No 1 hippie 57 43 26 26 0
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 Not Cancer Driver No 1 intact, hippie 124 357 43 43 0
SRF SRF P11831 Serum response factor chr6 Not Cancer Driver No 1 hippie 44 443 42 42 0
SRGN SRGN P10124 Serglycin chr10 Not Cancer Driver No 1 hippie 25 87 13 13 0
SUGP2_ENST00000452918 SUGP2 Q8IX01 SURP and G-patch domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 124 651 74 74 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 165 572 87 87 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
TANC2 TANC2 Q9HCD6 Protein TANC2 chr17 Not Cancer Driver No 1 hippie, biogrid 278 999 127 127 1
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 1 intact, hippie 55 205 27 27 0
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 hippie 41 41 4 4 10
THAP7_ENST00000399133 THAP7 Q9BT49 THAP domain-containing protein 7 chr22 Not Cancer Driver No 1 intact, hippie 34 214 24 24 0
THEG THEG Q9P2T0 Testicular haploid expressed gene protein chr19 Not Cancer Driver No 1 hippie 84 238 62 62 0
THSD4 THSD4 Q6ZMP0 Thrombospondin type-1 domain-containing protein 4 chr15 Not Cancer Driver No 1 hippie, biogrid 172 410 62 62 0
THSD7A THSD7A Q9UPZ6 Thrombospondin type-1 domain-containing protein 7A chr7 Not Cancer Driver No 1 hippie, biogrid 408 224 74 74 0
TJAP1 TJAP1 Q5JTD0 Tight junction-associated protein 1 chr6 Not Cancer Driver No 3 hippie, biogrid 74 442 65 65 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 Not Cancer Driver No 1 intact, hippie 101 458 89 89 0
TMEM14B_ENST00000379542 TMEM14B Q9NUH8 Transmembrane protein 14B chr6 Not Cancer Driver No 1 hippie 13 0 0 0 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX Census Yes 1 hippie 7 44 7 7 0
TMX3 TMX3 Q96JJ7 Protein disulfide-isomerase TMX3 chr18 Not Cancer Driver No 1 intact, hippie 50 49 9 9 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 hippie 132 799 63 63 0
TOPBP1 TOPBP1 Q92547 DNA topoisomerase 2-binding protein 1 chr3 Not Cancer Driver No 1 hippie 169 577 59 59 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 Not Cancer Driver No 1 hippie 59 410 39 39 2
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 2 intact, hippie 59 87 11 11 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 Census, Compendium Yes 1 hippie, biogrid 110 617 51 51 0
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 intact, hippie 62 268 19 19 0
TRO TRO Q12816 Trophinin chrX Not Cancer Driver No 1 intact, hippie 220 593 81 81 0
TSGA10IP TSGA10IP Q3SY00 Testis-specific protein 10-interacting protein chr11 Not Cancer Driver No 1 intact, hippie 79 552 79 79 0
TTLL10_ENST00000379289 TTLL10 Q6ZVT0 Inactive polyglycylase TTLL10 chr1 Not Cancer Driver No 2 intact, hippie 64 314 22 22 0
TUBA3E TUBA3E Q6PEY2 Tubulin alpha-3E chain chr2 Not Cancer Driver No 1 hippie 92 35 9 9 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 2 intact, hippie 148 213 29 29 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 intact, hippie 16 16 3 3 0
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 Not Cancer Driver No 1 hippie 45 173 16 16 0
VWC2L VWC2L B2RUY7 von Willebrand factor C domain-containing protein 2-like chr2 Not Cancer Driver No 1 intact, hippie 75 10 4 4 0
WAPL_ENST00000618527 WAPL Q7Z5K2 Wings apart-like protein homolog chr10 Not Cancer Driver No 1 hippie 140 621 68 68 0
WDR25_ENST00000402312 WDR25 Q64LD2 WD repeat-containing protein 25 chr14 Not Cancer Driver No 1 hippie 75 198 19 19 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 278 1959 223 223 0
YPEL3_ENST00000566595 YPEL3 P61236 Protein yippee-like 3 chr16 Not Cancer Driver No 1 hippie 13 0 0 0 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
ZBTB21 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 3 intact, hippie, biogrid 136 645 75 75 0
ZCCHC14 ZCCHC14 Q8WYQ9 Zinc finger CCHC domain-containing protein 14 chr16 Not Cancer Driver No 1 intact, hippie 121 725 84 84 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 Not Cancer Driver No 1 intact, hippie 43 262 34 34 0
ZMYM4 ZMYM4 Q5VZL5 Zinc finger MYM-type protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 159 660 53 53 0
ZMYM6 ZMYM6 O95789 Zinc finger MYM-type protein 6 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 125 229 29 29 0
ZNF417 ZNF417 Q8TAU3 Zinc finger protein 417 chr19 Not Cancer Driver No 1 intact, hippie 76 156 23 23 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 Not Cancer Driver No 6 intact, hippie, biogrid 101 694 83 83 0
ZNF587 ZNF587 Q96SQ5 Zinc finger protein 587 chr19 Not Cancer Driver No 1 intact, hippie 81 155 22 22 0
ZSWIM9_ENST00000328759 ZSWIM9 Q86XI8 Uncharacterized protein ZSWIM9 chr19 Not Cancer Driver No 1 hippie 14 180 3 3 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 3 hippie, biogrid 83 385 52 52 0